MikaelLeeRinneMD

PubMed

• 1 citations
  Phase Ib study of sabatolimab (MBG453), a novel immunotherapy targeting TIM-3 antibody, in combination with decitabine or azacitidine in high- or very high-risk myelod...
  Andrew M Brunner, Jordi Esteve, Kimmo Porkka, Steve Knapper, Elie Traer, Sebastian Scholl, Guillermo Garcia-Manero, Norbert Vey, Martin Wermke, Jeroen J W M Janssen, R...> ;American Journal of Hematology. 2024 Feb 1
• 3 citations
  Inaugural Results of the Individualized Screening Trial of Innovative Glioblastoma Therapy: A Phase II Platform Trial for Newly Diagnosed Glioblastoma Using Bayesian A...
  Rifaquat Rahman, Lorenzo Trippa, Eudocia Q Lee, Isabel Arrillaga-Romany, Geoffrey Fell, Mehdi Touat, Christine McCluskey, Jennifer Wiley, Sarah Gaffey, Jan Drappatz, M...> ;Journal of Clinical Oncology. 2023 Dec 20
• 3 citations
  Sabatolimab (MBG453) model-informed drug development for dose selection in patients with myelodysplastic syndrome/acute myeloid leukemia and solid tumors.
  Siyan Xu, Na Zhang, Mikael L Rinne, Haiying Sun, Andrew M Stein> ;CPT. 2023 Nov 1
• 39 citations
  Activity of PD-1 blockade with Nivolumab among patients with recurrent atypical/anaplastic meningioma: Phase II trial results.
  Wenya Linda Bi, Lakshmi Nayak, David Meredith, Joseph Driver, Ziming Du, Samantha E Hoffman, Yvonne Y. Li, Eudocia Q. Lee, Rameen Beroukhim, Mikael L. Rinne, Ricardo M...> ;Neuro-Oncology. 2021 May 20
• 12 citations
  A phase I, dose-escalation study of oral PIM447 in Japanese patients with relapsed and/or refractory multiple myeloma
  Shinsuke Iida, Kazutaka Sunami, Hironobu Minami, Kiyohiko Hatake, Risa Sekiguchi, Kazuto Natsume, Norifumi Ishikawa, Mikael L. Rinne, Masafumi Taniwaki> ;International Journal of Hematology. 2021 Feb 27
• 47 citations
  Individualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT): A Bayesian Adaptive Platform Trial to Develop Precision Medicines for Patients With Gliobl...
  Brian M. Alexander, Lorenzo Trippa, Sarah C. Gaffey, Isabel Arrillaga-Romany, Eudocia Q. Lee, Mikael L. Rinne, Manmeet Ahluwalia, Howard Colman, Geoffrey Fell, Evanthi...> ;JCO Precision Oncology. 2019 Mar 27
• 90 citations
  Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial.
  Patrick Y. Wen, Mehdi Touat, Brian M. Alexander, Ingo K. Mellinghoff, Shakti Ramkissoon, Christine McCluskey, Kristine Pelton, Sam Haidar, Sankha S. Basu, Sarah C. Gaf...> ;Journal of Clinical Oncology. 2019 Feb 4
• 50 citations
  PD-1 inhibition has only limited clinical benefit in patients with recurrent high-grade glioma.
  Sylvia Kurz, David Hastie, Raymond Y. Huang, Prashin Unadkat, Mikael L. Rinne, Lakshmi Nayak, Eudocia Q. Lee, David A. Reardon, Patrick Y. Wen> ;Neurology. 2018 Oct 2
• 19 citations
  Synergistic interactions with PI3K inhibition that induce apoptosis
  Yaara Zwang, Oliver Jonas, Casandra Chen, Mikael L. Rinne, John G. Doench, Federica Piccioni, Li Tan, Hai-Tsang Huang, Jinhua Wang, Young Jin Ham, Joyce T. O’Connell, ...> ;Elife. 2017 May 31
• 70 citations
  Central nervous system involvement by Waldenström macroglobulinaemia (Bing-Neel syndrome): a multi-institutional retrospective study
  Jorge J. Castillo, Shirley D'Sa, Michael P. Lunn, Monique C. Minnema, Alessandra Tedeschi, Frederick Lansigan, M. Lia Palomba, Marzia Varettoni, Ramón García-Sanz, Lak...> ;British Journal of Haematology. 2016 Mar 1
• 126 citations
  Extent of resection and overall survival for patients with atypical and malignant meningioma
  Ayal A. Aizer, Wenya Linda Bi, Manjinder Singh Kandola, Eudocia Q. Lee, Lakshmi Nayak, Mikael L. Rinne, Andrew D. Norden, Rameen Beroukhim, David A. Reardon, Patrick Y...> ;Cancer. 2015 Dec 15
• 66 citations
  TERT promoter mutations and monoallelic activation of TERT in cancer.
  Franklin W. Huang, Craig M. Bielski, Mikael L. Rinne, William C. Hahn, William R. Sellers, Frank Stegmeier, Levi A. Garraway, Gregory V. Kryukov> ;Oncogenesis. 2015 Dec 14
• 40 citations
  Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma.
  Shakti Ramkissoon, Wenya Linda Bi, Steven E. Schumacher, Lori A. Ramkissoon, Sam Haidar, David S. Knoff, Adrian M. Dubuc, Loreal Brown, Margot Burns, Jane Cryan, Malak...> ;Neuro-Oncology. 2015 Oct 1
• 63 citations
  A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma
  Ayal A. Aizer, Malak Abedalthagafi, Wenya Linda Bi, M.C. Horvath, Nils D. Arvold, Ossama Al-Mefty, Eudocia Q. Lee, Lakshmi Nayak, Mikael L. Rinne, Andrew D. Norden, Da...> ;Neuro-Oncology. 2015 Aug 30
• 65 citations
  Rapid Intraoperative Molecular Characterization of Glioma
  Ganesh M. Shankar, Joshua M. Francis, Mikael L. Rinne, Shakti Ramkissoon, Franklin W. Huang, Andrew S. Venteicher, Elliot H. Akama-Garren, Yun Jee Kang, Nina Lelic, Ja...> ;JAMA Oncology. 2015 Aug 1
• 87 citations
  Phase II study of panobinostat in combination with bevacizumab for recurrent glioblastoma and anaplastic glioma
  Eudocia Q. Lee, David A. Reardon, David Schiff, Jan Drappatz, Alona Muzikansky, Sean Grimm, Andrew D. Norden, Lakshmi Nayak, Rameen Beroukhim, Mikael L. Rinne, Andrew ...> ;Neuro-Oncology. 2015 Jun 1
• 1 citations
  Treating anaplastic oligodendrogliomas and WHO grade 2 gliomas: PCV or temozolomide? The case for temozolomide.
  Mikael L. Rinne, Patrick Y. Wen> ;Oncology. 2015 Apr 15
• 27 citations
  Phase 2 study of bosutinib, a Src inhibitor, in adults with recurrent glioblastoma
  Jennie Taylor, Jorg Dietrich, Elizabeth R. Gerstner, Andrew D. Norden, Mikael L. Rinne, Daniel P. Cahill, Anat Stemmer-Rachamimov, Patrick Y. Wen, Rebecca A. Betensky,...> ;Journal of Neuro-Oncology. 2015 Feb 1
• 37 citations
  Phase II trial of triple tyrosine kinase receptor inhibitor nintedanib in recurrent high-grade gliomas
  Andrew D. Norden, David Schiff, Manmeet Ahluwalia, Glenn J. Lesser, Lakshmi Nayak, Eudocia Q. Lee, Mikael L. Rinne, Alona Muzikansky, Jorg Dietrich, Benjamin Purow, Li...> ;Journal of Neuro-Oncology. 2015 Jan 1
• 72 citations
  Adjuvant radiation therapy, local recurrence, and the need for salvage therapy in atypical meningioma
  Ayal A. Aizer, Nils D. Arvold, Paul J. Catalano, Elizabeth B. Claus, Alexandra J. Golby, Mark D. Johnson, Ossama Al-Mefty, Patrick Y. Wen, David A. Reardon, Eudocia Q....> ;Neuro-Oncology. 2014 Nov 1
• 40 citations
  A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy
  Eudocia Q. Lee, Alona Muzikansky, Jan Drappatz, Santosh Kesari, Eric T. Wong, Camilo E. Fadul, David A. Reardon, Andrew D. Norden, Lakshmi Nayak, Mikael L. Rinne, Bria...> ;Neuro-Oncology. 2014 Nov 1
• 19 citations
  Retrospective study of carmustine or lomustine with bevacizumab in recurrent glioblastoma patients who have failed prior bevacizumab.
  Rifaquat Rahman, Kelly Hempfling, Andrew D. Norden, David A. Reardon, Lakshmi Nayak, Mikael L. Rinne, Rameen Beroukhim, Lisa Doherty, Sandra Ruland, Arun Rai, Jennifer...> ;Neuro-Oncology. 2014 Nov 1
• 26 citations
  Update on bevacizumab and other angiogenesis inhibitors for brain cancer.
  Mikael L. Rinne, Eudocia Q. Lee, Lakshmi Nayak, Andrew D. Norden, Rameen Beroukhim, Patrick Y. Wen, David A. Reardon> ;Expert Opinion on Emerging Drugs. 2013 Jun 2
• 32 citations
  Central Nervous System Complications of Cancer Therapy
  Mikael L. Rinne, Eudocia Q. Lee, Patrick Y. Wen> ;The Journal of Supportive Oncology. 2012 Apr 27
• 411 citations
  Emerging insights into the molecular and cellular basis of glioblastoma
  Gavin P. Dunn, Mikael L. Rinne, Jill Wykosky, Giannicola Genovese, Steven N. Quayle, Ian F. Dunn, Pankaj K. Agarwalla, Milan G. Chheda, Benito Campos, Alan Wang, Camer...> ;Genes & Development. 2012 Apr 15
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