MinJaniceLuMD

PubMed

• 8 citations
  Tucatinib has Selective Activity in HER2-Positive Cancers and Significant Combined Activity with Approved and Novel Breast Cancer-Targeted Therapies.
  Neil A O'Brien, Holly K T Huang, Martina S J McDermott, Athena M Madrid, Tong Luo, Raul Ayala, Shawnt Issakhanian, Ke Wei Gong, Ming Lu, Jun Zhang, Dennis J Slamon> ;Molecular Cancer Therapeutics. 2022 May 4
• 2 citations
  Characterization of disease-propagating stem cells responsible for myeloproliferative neoplasm-blast phase.
  Xiaoli Wang, Raajit K Rampal, Cing Siang Hu, Joseph Tripodi, Noushin Farnoud, Bruce Petersen, Michael R Rossi, Minal Patel, Erin McGovern, Vesna Najfeld, Camelia Iancu...> ;JCI Insight. 2022 Apr 22
• 1 citations
  Combined Drug Targeting of p53-dependent and -independent Pathways Depletes Myelofibrosis Hematopoietic Stem/Progenitor Cells.
  Min Lu, Lijuan Xia, Nada Elmansy, Cara Clementelli, Douglas Tremblay> ;Leukemia. 2021 Oct 12
• 17 citations
  Transient expansion of TP53 mutated clones in polycythemia vera patients treated with idasanutlin
  Bridget K. Marcellino, Noushin Farnoud, Bruno Cassinat, Min Lu, Emanuelle Verger, Erin McGovern, Minal Patel, Juan S. Medina-Martinez, Max Levine, Juanes E. Arango Oss...> ;Blood Advances. 2020 Nov 24
• 64 citations
  Disruption of IRE1α through its kinase domain attenuates multiple myeloma.
  Jonathan M. Harnoss, Adrien Le Thomas, Anna Shemorry, Scot A. Marsters, David A. Lawrence, Min Lu, Yung-Chia Ariel Chen, Jing Qing, Klara Totpal, David Kan, Ehud Segal...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Aug 13
• 62 citations
  Oral Idasanutlin in Patients with Polycythemia Vera
  John Mascarenhas, Min Lu, Heidi E. Kosiorek, Elizabeth Virtgaym, Lijuan Xia, Lonette Sandy, Ruben A. Mesa, Bruce Petersen, Noushin Farnoud, Vesna Najfeld, Raajit K. Ra...> ;Blood. 2019 Aug 8
• 43 citations
  Advanced forms of MPNs are accompanied by chromosomal abnormalities that lead to dysregulation of TP53.
  Bridget K. Marcellino, Ronald Hoffman, Joseph Tripodi, Min Lu, Heidi E. Kosiorek, John Mascarenhas, Raajit K. Rampal, Amylou C. Dueck, Vesna Najfeld> ;Blood Advances. 2018 Dec 26
• 104 citations
  Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
  Tsun-Kai Chang, David A. Lawrence, Min Lu, Jenille Tan, Jonathan M. Harnoss, Scot A. Marsters, Peter Liu, Wendy Sandoval, Scott E. Martin, Avi Ashkenazi> ;Molecular Cell. 2018 Aug 16
• 2 citations
  A phase II study of panobinostat in patients with primary myelofibrosis (PMF) and post-polycythemia vera/essential thrombocythemia myelofibrosis (post-PV/ET MF).
  John Mascarenhas, Lonette Sandy, Min Lu, James Yoon, Bruce Petersen, David Zhang, Fei Ye, Carrie Newsom, Vesna Najfeld, Tsivia Hochman, Judith D Goldberg, Ronald Hoffman> ;Leukemia Research. 2017 Feb 1
• 28 citations
  Group I Paks Promote Skeletal Myoblast Differentiation In Vivo and In Vitro.
  Giselle A. Joseph, Min Lu, Maria Radu, Jennifer K. Lee, Steven J. Burden, Jonathan Chernoff, Robert S. Krauss> ;Molecular and Cellular Biology. 2017 Feb 1
• 8 citations
  Alox5 Blockade Eradicates JAK2V617F-Induced Polycythemia Vera in Mice
  Yaoyu Chen, Yi Shan, Min Lu, Ngoc DeSouza, Zhiru Guo, Ronald Hoffman, Ai-Bing Liang, Shaoguang Li> ;Cancer Research. 2017 Jan 1
• 57 citations
  Lipocalin produced by myelofibrosis cells affects the fate of both hematopoietic and marrow microenvironmental cells
  Min Lu, Lijuan Xia, Yen-Chun Liu, Tsivia Hochman, Laetizia Bizzari, Daniel Aruch, Jane Lew, Rona Singer Weinberg, Judith D. Goldberg, Ronald Hoffman> ;Blood. 2015 Aug 20
• 54 citations
  The orally bioavailable MDM2 antagonist RG7112 and pegylated interferon α 2a target JAK2V617F-positive progenitor and stem cells.
  Min Lu, Lijuan Xia, Yan Li, Xiaoli Wang, Ronald Hoffman> ;Blood. 2014 Jul 31
• 406 citations
  Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis.
  Min Lu, David A. Lawrence, Scot A. Marsters, Diego Acosta-Alvear, Philipp Kimmig, Aaron S Mendez, Adrienne W. Paton, James C. Paton, Peter Walter, Avi Ashkenazi> ;Science. 2014 Jul 4
• 78 citations
  E-cadherin couples death receptors to the cytoskeleton to regulate apoptosis.
  Min Lu, Scot A. Marsters, Xiaofen Ye, Elizabeth Luis, Lino C. Gonzalez, Avi Ashkenazi> ;Molecular Cell. 2014 Jun 19
• 66 citations
  Apoptosis initiation through the cell-extrinsic pathway.
  Pradeep M. Nair, Min Lu, Sean Petersen, Avi Ashkenazi> ;Methods in Enzymology. 2014 Jan 1
• 16 citations
  Molecular epidemiological survey of hemoglobinopathies in the Wuxi region of Jiangsu Province, eastern China.
  Min Lin, Zhi-Jun Han, Qian Wang, Lei Zheng, Yan Wang, Hui Yang, Yue Huang, Fen Lin, Xiao-Fen Zhan, Chun-Ping Lin, Jiao-Ren Wu, Zhao-Yun Luo, Jing-Bo Liu, Zhi-He Yan, S...> ;Hemoglobin. 2013 Sep 5
• 63 citations
  A phase I study of panobinostat (LBH589) in patients with primary myelofibrosis (PMF) and post‐polycythaemia vera/essential thrombocythaemia myelofibrosis (post‐PV/ET MF)
  John Mascarenhas, Min Lu, Timmy Li, Bruce Petersen, Tsivia Hochman, Vesna Najfeld, Judith D. Goldberg, Ronald Hoffman> ;British Journal of Haematology. 2013 Apr 1
• 110 citations
  Structures of a Na+-coupled, substrate-bound MATE multidrug transporter
  Min Lu, Jindrich Symersky, Martha Radchenko, Akiko Koide, Yi Guo, Rongxin Nie, Shohei Koide> ;Proceedings of the National Academy of Sciences of the United States of America. 2013 Feb 5
• 67 citations
  Spleens of myelofibrosis patients contain malignant hematopoietic stem cells
  Xiaoli Wang, Sonam Prakash, Min Lu, Joseph Tripodi, Fei Ye, Vesna Najfeld, Yan Li, Myron Schwartz, Rona Singer Weinberg, Paul Roda, Attilio Orazi, Ronald Hoffman> ;The Journal of Clinical Investigation. 2012 Nov 1
• 5 citations
  p53 as a target in myeloproliferative neoplasms.
  Min Lu, Ronald Hoffman> ;Oncotarget. 2012 Oct 28
• 49 citations
  Combination treatment in vitro with Nutlin, a small-molecule antagonist of MDM2, and pegylated interferon-α 2a specifically targets JAK2V617F-positive polycythemia ver...
  Min Lu, Xiaoli Wang, Yan Li, Joseph Tripodi, Goar Mosoyan, John Mascarenhas, Marina Kremyanskaya, Vesna Najfeld, Ronald Hoffman> ;Blood. 2012 Oct 11
• 16 citations
  Revelation of a catalytic calcium-binding site elucidates unusual metal dependence of a human apyrase.
  David Rooklin, Min Lu, Yingkai Zhang> ;Journal of the American Chemical Society. 2012 Sep 19
• 18 citations
  Prevention of Doxorubicin Cardiopathic Changes by a Benzyl Styryl Sulfone in Mice
  Min Lu, Salim Merali, Ronald E. Gordon, Jian-Dong Jiang, Yan Li, John Mandeli, Xunbao Duan, John T. Fallon, James F. Holland> ;Genes & Cancer. 2011 Oct 1
• 50 citations
  Protein-RNA and Protein-Protein Recognition by Dual KH1/2 Domains of the Neuronal Splicing Factor Nova-1
  Marianna Teplova, Lucy Malinina, Jennifer C. Darnell, Jikui Song, Min Lu, Ruben Abagyan, Kiran Musunuru, Alexei Teplov, Stephen K. Burley, Robert B. Darnell, Dinshaw J...> ;Structure. 2011 Jul 13
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Abstracts/Posters

• Significance of Abnormalities of PPM1D in Myeloproliferative Neoplasms
  Min Lu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Expansion of Prior Existing TP53 Mutated Clones in Polycythemia Vera Patients Treated with Idasanutlin
  Min Lu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

• A Novel Combination of Drugs Which Target Both the Intrinsic and Extrinsic Apoptotic Pathways to Eliminate Myelofibrosis CD34+ Cells 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019