Tait Shanafelt, MD, Oncology, Palo Alto, CA

TaitDShanafeltMD

Oncology Palo Alto, CA

Hematologic Oncology

Professor, Internal Medicine, Mayo Medical School

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Summary

  • Dr. Shanafelt's clinical and scientific interests are focused on the treatment of patients with chronic lymphocytic leukemia (CLL). CLL is the most common leukemia in adults and, although treatable, it is currently an incurable illness. Dr. Shanafelt's research on CLL spans the continuum from the laboratory to the clinic. He is currently the principle investigator on multiple clinical trials testing new treatments for patients with CLL as well as being involved in the design and conduct of CLL trials for the Eastern Cooperative Oncology Group. His laboratory work involves identifying prognostic tools that help predict which CLL patients will experience a more aggressive disease course as well as research to identify new compounds for treating the disease. The mechanism of action of promising compounds are further explored in different micro-environments to evaluate in vivo modulators of drug induced killing/apoptosis. Promising candidate drugs are then taken in to phase I/II clinical trials for patients with CLL. Dr. Shanafelt's other academic interest is physician well-being and its impact on patient care. He is the director of the Mayo Clinic Department of Medicine Program on Physician Well-being, a clinical laboratory evaluating personal and organizational factors that contribute to physician satisfaction. His research in this area has involved physicians at all stages of their career from medical school to practice had has include several multi-center and national studies. This research is intended to identify personal and organizational factors that can be modified in order to promote physician well-being and enhance the quality of care physicians deliver.

Education & Training

  • Mayo School of Graduate Medical Education
    Mayo School of Graduate Medical EducationFELLOWSHIP
  • University of Washington
    University of WashingtonRESIDENCY
  • University of Colorado Denver School of Medicine
    University of Colorado Denver School of MedicineMEDICAL_SCHOOL
  • Washington State UniversityOTHER_TRAINING
  • Washington State UniversityOTHER_TRAINING

Certifications & Licensure

  • CA State Medical License
    CA State Medical License 2017 - 2022
  • ID State Medical License
    ID State Medical License 2014 - 2018
  • ND State Medical License
    ND State Medical License 2014 - 2017
  • CO State Medical License
    CO State Medical License 2013 - 2019
  • MO State Medical License
    MO State Medical License 2013 - 2018
  • KY State Medical License
    KY State Medical License 2013 - 2018
  • FL State Medical License
    FL State Medical License 2013 - 2016
  • American Board of Internal Medicine Internal Medicine
  • American Board of Internal Medicine Hematology
  • American Board of Internal Medicine Medical Oncology
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Awards, Honors, & Recognition

  • Best Research Poster Award Winner CDIM, 2005
  • Mayo Clinic Summerskill Award Mayo Clinic, 2005
  • Hematology/Oncology Outstanding Achievement Award Mayo Clinic, 2005
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Clinical Trials

Publications & Presentations

PubMed

Books/Book Chapters

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Abstracts/Posters

  • Developmental DNA Methylation Subtype Predicts Progression to Treatment and Survival in High-Count Monoclonal B Lymphocytosis
    Tait D. Shanafelt, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
  • The AKT Inhibitor MK2206 In Combination With Rituximab and Bendamustine Is Tolerable and Active In Relapsed Or Refractory Chronic Lymphocytic Leukemia: Results From a ...
    Wei Ding, MD, PhD, Shanafelt TD, Clive S. Zent, MD, Jose F. Leis, MD, PhD, Betsy R. LaPlant, Timothy G. Call, MD, Curtis A Hanson, Charles Erlichmanm, Thomas Habermann..., ASH Annual Meeting, 1/1/2013
  • CD49d Is The Strongest Flow Cytometry-Based Predictor Of Overall Survival In Chronic Lymphocytic Leukemia.
    Pietro Bulian, MD, Shanafelt TD, Chris Fegan, MBBS, Antonella Zucchetto, Lilla Cro, PhD, Holger Nuckel, MD, Luca Baldini, Antonina Kurtova, MS, Alessandra Ferrajoli, M..., Blood, ASH Annual Meeting, 1/1/2013
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Lectures

  • 50th Annual Louis F. Bishop Keynote: Reducing Burnout and Promoting Engagement: Individual and Organizational Approaches to Physician Well-being 
    2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
  • Clinician Wellness Intensive I Featuring the 50th Annual Louis F. Bishop Keynote 
    2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
  • Ibrutinib-Based Therapy Improves Anti-Tumor T Cell Killing Function Allowing Effective Pairing with Anti-PD-L1 Immunotherapy Compared to Traditional FCR Chemoimmunothe... 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
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Authored Content

  • Burnout, Depression, Career Satisfaction, and Work-Life Integration by Physician Race/EthnicityAugust 2020
  • Resilience and Burnout Among Physicians and the General US Working PopulationJuly 2020
  • Resilience and Burnout Among Physicians and the General US Working PopulationJuly 2020
  • Understanding and Addressing Sources of Anxiety Among Health Care Professionals During the COVID-19 PandemicApril 2020
  • Seeking Solutions to Physician BurnoutAugust 2018
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Press Mentions

  • Burnout in the Age of COVID-19
    Burnout in the Age of COVID-19August 10, 2020
  • COVID-19: FAQs-Congenital Heart Surgery Recovery and Defining a "New Normal"
    COVID-19: FAQs-Congenital Heart Surgery Recovery and Defining a "New Normal"July 14, 2020
  • Courage, Fortitude, and Effective Leadership of Surgical Teams During COVID-19
    Courage, Fortitude, and Effective Leadership of Surgical Teams During COVID-19July 10, 2020
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Grant Support

  • The Role Of Oxidative Stress In CLL B-Cell ApoptosisNational Cancer Institute2006–2010

Professional Memberships