MustaphaEzzeddineMD

Neurology • Winston Salem, NC

Vascular Neurology, Neurocritical Care

Professor, Vice Chair for Clinical Affairs

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Office
1 Medical Center Boulevard
Winston Salem, NC 27157
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Education & Training

Duke University HospitalResidency, Neurology, 1993 - 1997
American University of Beirut Faculty of MedicineClass of 1993

Certifications & Licensure

NC State Medical License 1993 - 2024
MN State Medical License 2007 - 2020
NJ State Medical License 2005 - 2007
GA State Medical License 2002 - 2005
DC State Medical License 2001 - 2002
MD State Medical License 2000 - 2002
MA State Medical License 1997 - 2000
American Board of Psychiatry and Neurology Neurology
American Board of Psychiatry and Neurology Vascular Neurology
Neurocritical careNeurocritical care

Clinical Trials

Albumin in Acute Ischemic Stroke Trial Start of enrollment: 2006 Jun 01
Terminated
Phase 3
Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial Start of enrollment: 2010 May 28
Terminated
Phase 3
Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial Start of enrollment: 2012 Apr 01
Completed
Phase 3
Solitaire™ With the Intention For Thrombectomy as PRIMary Endovascular Treatment (SWIFT PRIME) Trial Start of enrollment: 2012 Dec 01
Completed
Not Applicable
Study of Procoagulation Markers in Stroke Patients Start of enrollment: 2012 Aug 01
Completed
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial Start of enrollment: 2014 Dec 09
Recruiting
Not Applicable
Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke 3 Start of enrollment: 2016 Apr 01
Terminated
Not Applicable
AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke Start of enrollment: 2018 Jan 19
Terminated
Phase 3
Sleep for Stroke Management and Recovery Trial Start of enrollment: 2019 May 09
Recruiting
Not Applicable
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Publications & Presentations

PubMed

New challenges for emergent neuroimaging: beyond the NISSAN study.
Mustapha A. Ezzeddine, David S Liebeskind, Adnan I. Qureshi> ;Journal of Neuroimaging. 2009 Apr 1
Antihypertensive treatment of acute cerebral hemorrhage.
Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH) investigators> ;Critical care medicine.
10 citations
Patient Experiences with Ambulatory Telehealth in Neurology: Results of a Mixed Methods Study
Sharon Thomson, Lauren Strauss, Rachel Graham, Mustapha Ezzeddine, Kristen A. Dodenhoff, Alexander Ambrosini, Laura Daniela Smith, Laura Silla, Caroline Caraci, Amy K ...> ;Neurology. Clinical Practice. 2021 Mar 10
2 citations
Patterns and Predictors of Extra-Corporeal Membrane Oxygenation Related Cerebral Microbleeds.
Karan Topiwala, Haitham M. Hussein, Kamran Masood, Andrew Zhang, Bhavani Kashyap, Jason A. Bartos, Hüseyin Gürkan Töre, Eva Mistry, Bentho Oladi, Bharathi D. Jagadeesa...> ;Journal of Stroke and Cerebrovascular Diseases. 2022 Jan 1
29 citations
Rapid Implementation of Outpatient Teleneurology in Rural Appalachia: Barriers and Disparities.
, , , , , , , , , , , , , , , , > ;Neurology. Clinical Practice. 2021 Jun 1
6 citations
Neurotoxicity of antibodies in cancer therapy: A review.
Erika Horta, Connie Bongiorno, Mustapha A. Ezzeddine, Elizabeth Neil> ;Clinical Neurology and Neurosurgery. 2020 Jan 1
Intensive vs Standard Treatment of Hyperglycemia and Functional Outcome in Patients With Acute Ischemic Stroke: The SHINE Randomized Clinical Trial.
Johnston KC, Bruno A, Pauls Q, Hall CE, Barrett KM, Barsan W, Fansler A, Van de Bruinhorst K, Janis S, Durkalski-Mauldin VL, Neurological Emergencies Treatment Trials ...> ;JAMA.
249 citations
Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-a...
Bruce C.V. Campbell, Charles B. L. M. Majoie, Gregory W. Albers, Bijoy K Menon, Nawaf Yassi, Gagan Sharma, Wim H. van Zwam, Robert J. van Oostenbrugge, Andrew M. Demch...> ;The Lancet. Neurology. 2019 Jan 1
5 citations
Basal ganglia hemorrhage in a case report following spinal surgery.
Brent Berry, Malik Ghannam, Caitlin Bell, Sami Ghazaleh, Sherief Boss, Christopher Streib, Mustapha A. Ezzeddine> ;BMC Neurology. 2018 Dec 14
4 citations
Unplanned 30-Day Hospital Readmissions of Symptomatic Carotid and Vertebral Artery Dissection.
Tapan Mehta, Smit Patel, Shailesh Male, Romil Parikh, Kathan Mehta, Kamakshi Lakshminarayan, Ramachandra P. Tummala, Mustapha A. Ezzeddine> ;Journal of Stroke. 2018 Sep 30
Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data.
Román LS, Menon BK, Blasco J, Hernández-Pérez M, Dávalos A, Majoie CBLM, Campbell BCV, Guillemin F, Lingsma H, Anxionnat R, Epstein J, Saver JL, Marquering H, Wong JH,...> ;The Lancet. Neurology. 2018-09-18
23 citations
A mHealth-based care model for improving hypertension control in stroke survivors: Pilot RCT.
Kamakshi Lakshminarayan, Sarah M. Westberg, Carin Northuis, Candace C. Fuller, Farha S Ikramuddin, Mustapha A. Ezzeddine, Julie Scherber, Stuart M. Speedie> ;Contemporary Clinical Trials. 2018 May 12
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
Johnston SC, Easton JD, Farrant M, Barsan W, Conwit RA, Elm JJ, Kim AS, Lindblad AS, Palesch YY, Clinical Research Collaboration, Neurological Emergencies Treatment Tr...> ;The New England journal of medicine. 2018-05-16
1 citations
Outcomes of early carotid stenting and angioplasty in large-vessel anterior circulation strokes treated with mechanical thrombectomy and intravenous thrombolytics
Tapan Mehta, Ninad Desai, Kathan Mehta, Romil Parikh, Shailesh Male, Mohammed Hussain, Martin Ollenschleger, Gary Spiegel, Andrew W. Grande, Mustapha A. Ezzeddine, Bha...> ;Interventional Neuroradiology. 2018 Apr 26
Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a met...
Campbell BCV, van Zwam WH, Goyal M, Menon BK, Dippel DWJ, Demchuk AM, Bracard S, White P, Dávalos A, Majoie CBLM, van der Lugt A, Ford GA, de la Ossa NP, Kelly M, Bour...> ;The Lancet. Neurology. 2017-12-16
11 citations
Hyperglycemia in acute ischemic stroke: Is it time to re-evaluate our understanding?
Rwoof Reshi, Christopher Streib, Mustapha A. Ezzeddine, Michelle H. Biros, Benjamin R. Miller, Kamakshi Lakshminarayan, David C. Anderson, Agnieszka Ardelt> ;Medical Hypotheses. 2017 Sep 1
Phantom-based standardization of CT angiography images for spot sign detection
Andrea Morotti, Javier Romero, Michael J. Jessel, Andrew M. Hernandez, Anastasia Vashkevich, Kristin Schwab, Joseph D. Burns, Qaisar A. Shah, Thomas A. Bergman, M. Far...> ;Neuroradiology. 2017 Jul 20
Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke.
Saver JL, Goyal M, Bonafe A, Diener HC, Levy EI, Pereira VM, Albers GW, Cognard C, Cohen DJ, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal ...> ;The New England journal of medicine. 2015-04-17
9 citations
Intracranial Vascular Calcification is Protective from Vasospasm after Aneurysmal Subarachnoid Hemorrhage
Haitham M. Hussein, Haralabos Zacharatos, Steve M. Cordina, Kamakshi Lakshminarayan, Mustapha A. Ezzeddine> ;Journal of Stroke and Cerebrovascular Diseases. 2014 Nov 1
6 citations
Human herpesvirus 6 is associated with status epilepticus and hyponatremia after umbilical cord blood transplantation.
Fernanda Leite de Souza Franceschi, Jaime S. Green, Zuzan Cayci, Evan Mariash, Mustapha A. Ezzeddine, Veronika Bachanova, Celalettin Ustun> ;The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Medicale. 2014 May 1
4 citations
Clinical-Radiological Severity Mismatch Phenomenon: Patients with Severe Neurological Deficits Without Matching Infarction on Computed Tomographic Scan
Adnan I Qureshi, Saqib A Chaudhry, Kamesh Sivagnanam, Gustavo J. Rodriguez, M. Fareed K. Suri, Kamakshi Lakshminarayan, Mustapha A. Ezzeddine> ;Journal of Neuroimaging. 2013 Jan 1
2 citations
FLAIR with contrast linked to better correlation with stroke symptoms than diffision-weighted imaging in a patient: detecting hyperintense acute reperfusion injury mar...
Elissaios Karageorgiou, Daniel J. Schwab, Mustapha A. Ezzeddine> ;Cerebrovascular Diseases. 2012 Nov 8
2 citations
Approach to the patient with transient alteration of consciousness
Thomas R. Henry, Mustapha A. Ezzeddine> ;Neurology. Clinical Practice. 2012 Sep 1
10 citations
Agreement in endovascular thrombolysis patient selection based on interpretation of presenting CT and CT-P changes in ischemic stroke patients
Ameer E Hassan, Haralabos Zacharatos, Saqib A Chaudhry, M. Fareed K. Suri, Gustavo J. Rodriguez, Jefferson T. Miley, Alberto Maud, Robert A. Taylor, Mustapha A. Ezzedd...> ;Neurocritical Care. 2012 Feb 1
36 citations
Outcome of the ‘Drip-and-Ship’ Paradigm among Patients with Acute Ischemic Stroke: Results of a Statewide Study
Adnan I. Qureshi, Saqib A Chaudhry, Gustavo J. Rodriguez, M. Fareed K. Suri, Kamakshi Lakshminarayan, Mustapha A. Ezzeddine> ;Cerebrovascular Diseases Extra. 2012 Jan 1
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