NathanJeromeSmischneyMD

Anesthesiology • Rochester, MN

Critical Care Medicine

Instructor, Anesthesiology, Mayo Medical School

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Office
200 1st St Sw
Rochester, MN 55905
Phone+1 507-284-2511
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Education & Training

Dartmouth-Hitchcock/Mary Hitchcock Memorial HospitalResidency, Anesthesiology, 2007 - 2011
University of Minnesota Medical SchoolClass of 2007

Certifications & Licensure

WI State Medical License 2013 - 2025
MN State Medical License 2011 - 2024
NH State Medical License 2019 - 2021
GA State Medical License 2015 - 2020
VT State Medical License 2019 - 2020
American Board of Anesthesiology Anesthesiology
American Board of Anesthesiology Critical Care Medicine

Clinical Trials

A Comparison of Ketofol (Ketamine and Propofol Admixture) Versus Propofol as Induction Agents on Hemodynamic Parameters Start of enrollment: 2010 Dec 01
Completed
Not Applicable
Ketamine / Propofol Admixture "Ketofol" at Induction in the Critically Ill Against Etomidate: KEEP PACE Trial Start of enrollment: 2014 Apr 01
Completed
Phase 2, Phase 3
Endotracheal Intubation Among the Critically Ill: HEMAIR Pilot Study Start of enrollment: 2015 Aug 01
Completed
Cardiac Output Monitoring in Critically Ill Patient Undergoing Intubation Start of enrollment: 2018 Jun 27
Completed
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Publications & Presentations

PubMed

Association of Shock Indices with Peri-Intubation Hypotension and Other Outcomes: A Sub-Study of the KEEP PACE Trial.
Nathan J Smischney, Mohamed O Seisa, Darrell R Schroeder> ;Journal of Intensive Care Medicine. 2024 Feb 25
Noninvasive Cardiac Output Monitoring (NICOM) in the Critically Ill Patient Undergoing Endotracheal Intubation: A Prospective Observational Study.
Nathan J Smischney, Anita D Stoltenberg, Darrell R Schroeder, Jillian L DeAngelis, David A Kaufman> ;Journal of Intensive Care Medicine. 2023 Dec 1
4 citations
Trajectory of PaO/FiORatio in Shock After Angiotensin II.
Patrick M Wieruszewski, Patrick J Coleman, Andrea R Levine, Danielle Davison, Nathan J Smischney, Shravan Kethireddy, Yanglin Guo, Jason Hecht, Michael A Mazzeffi, Jon...> ;Journal of Intensive Care Medicine. 2023 Oct 1
Clonidine use during dexmedetomidine weaning: A systematic review.
Sanu Rajendraprasad, Molly Wheeler, Erin Wieruszewski, Joseph Gottwald, Lindsey A Wallace, Danielle Gerberi, Patrick M Wieruszewski, Nathan J Smischney> ;World Journal of Critical Care Medicine. 2023 Jan 9
Pro: The Best Induction for the Physiologically Difficult Airway is Ketamine-Propofol Admixture ("Ketofol").
Benjamin D Brakke, Nathan J Smischney> ;Journal of Cardiothoracic and Vascular Anesthesia. 2023 Aug 1
2 citations
Thromboelastography Parameters do not Discriminate for Thrombotic Events in Hospitalized Patients With COVID-19.
Susan Kartiko, Naoru Koizumi, David Yamane, Babak Sarani, Abu B Siddique, Andrea R Levine, Amanda M Jackson, Patrick M Wieruszewski, Nathan J Smischney, Ashish K Khann...> ;Journal of Intensive Care Medicine. 2023 May 1
3 citations
Hypotension Prediction Score for Endotracheal Intubation in Critically Ill Patients: A Post Hoc Analysis of the HEMAIR Study.
Nathan J Smischney, Salim R Surani, Ashley Montgomery, Pablo Moreno Franco, Cynthia Callahan, Gozde Demiralp, Rudy Tedja, Sarah Lee, Santhi I Kumar, Ashish K Khanna> ;Journal of Intensive Care Medicine. 2022 Nov 1
1 citations
Intensive Care Unit Sedation Practices at a Large, Tertiary Academic Center.
Mikaela M Hofer, Patrick M Wieruszewski, Scott D Nei, Kristin Mara, Nathan J Smischney> ;Journal of Intensive Care Medicine. 2022 Oct 1
15 citations
Intraoperative hypotension is associated with persistent acute kidney disease after noncardiac surgery: a multicentre cohort study.
Andrew D Shaw, Ashish K Khanna, Nathan J Smischney, Apeksha V Shenoy, Isabel J Boero, Michael Bershad, Seungyoung Hwang, Qinyu Chen, Wolf H Stapelfeldt> ;British Journal of Anaesthesia. 2022 Jul 1
6 citations
Endotracheal intubation sedation in the intensive care unit.
Nathan J Smischney, Pritee Tarwade> ;World Journal of Critical Care Medicine. 2022 Jan 9
2 citations
Acute exacerbation of interstitial lung disease in the intensive care unit.
Antonios Charokopos, Teng Moua, Jay H Ryu, Nathan J Smischney> ;World Journal of Critical Care Medicine. 2022 Jan 9
6 citations
Association of perioperative hypotension with subsequent greater healthcare resource utilization.
Wolf H. Stapelfeldt, Ashish Khanna, Andrew D. Shaw, Apeksha V. Shenoy, Seungyoung Hwang, Mitali Stevens, Nathan J. Smischney> ;Journal of Clinical Anesthesia. 2021 Sep 15
21 citations
Postoperative Hypotension and Adverse Clinical Outcomes in Patients Without Intraoperative Hypotension, After Noncardiac Surgery.
Ashish Khanna, Andrew D. Shaw, Wolf H. Stapelfeldt, Isabel J. Boero, Qinyu Chen, Mitali Stevens, Anne Gregory, Nathan J. Smischney> ;Anesthesia and Analgesia. 2021 May 1
4 citations
Reintubation Summation Calculation: A Predictive Score for Extubation Failure in Critically Ill Patients.
Vikas Bansal, Nathan J Smischney, Rahul Kashyap, Zhuo Li, Alberto Marquez, Daniel A Diedrich, Jason L Siegel, Ayan Sen, Amanda D Tomlinson, Carla P Venegas-Borsellino,...> ;Frontiers in Medicine. 2021 Jan 1
4 citations
Vasopressin in vasoplegic shock: A systematic review
Andrew J Webb, Mohamed O. Seisa, Tarek Nayfeh, Patrick M. Wieruszewski, Scott D Nei, Nathan J. Smischney> ;World Journal of Critical Care Medicine. 2020 Dec 18
32 citations
Postoperative hypotension in patients discharged to the intensive care unit after non-cardiac surgery is associated with adverse clinical outcomes.
Nathan J. Smischney, Andrew D. Shaw, Wolf H. Stapelfeldt, Isabel J. Boero, Qinyu Chen, Mitali Stevens, Ashish Khanna> ;Critical Care. 2020 Dec 7
110 citations
Intraoperative Hypotension Is Associated With Adverse Clinical Outcomes After Noncardiac Surgery.
Anne Gregory, Wolf H. Stapelfeldt, Ashish Khanna, Nathan J. Smischney, Isabel J. Boero, Qinyu Chen, Mitali Stevens, Andrew D. Shaw> ;Anesthesia and Analgesia. 2021 Jun 1
4 citations
Risk Factors for and Outcomes Associated With Peri-Intubation Hypoxemia: A Multicenter Prospective Cohort Study
Nathan J. Smischney, Ashish Khanna, Ernesto Brauer, Lee E. Morrow, Uchenna R. Ofoma, David A. Kaufman, Ayan Sen, Chakradhar Venkata, Peter E. Morris, Vikas Bansal> ;Journal of Intensive Care Medicine. 2020 Oct 1
23 citations
Risk factors for and prediction of post-intubation hypotension in critically ill adults: A multicenter prospective cohort study.
Nathan J. Smischney, Rahul Kashyap, Ashish Khanna, Ernesto Brauer, Lee E. Morrow, Mohamed O. Seisa, Darrell R. Schroeder, Daniel A. Diedrich, Ashley A. Montgomery, Pab...> ;Plos One. 2020 Aug 31
3 citations
Description of Pharmacogenomic Testing Among Patients Admitted to the Intensive Care Unit After Cardiovascular Surgery.
Pamela E. Peterson, Wayne T. Nicholson, Ann M. Moyer, Christopher J. Arendt, Nathan J. Smischney, Troy G. Seelhammer, Catherine Krecke, Rory M. Haney, Elissa J. Yaw, L...> ;Journal of Intensive Care Medicine. 2021 Oct 1
3 citations
Effect of Ketamine/Propofol Admixture on Peri-Induction Hemodynamics: A Systematic Review and Meta-Analysis
Nathan J. Smischney, Mohamed O. Seisa, Allison S. Morrow, Oscar J. Ponce, Zhen Wang, Muayad A Alzuabi, Katherine J. Heise, Mohammad Hassan Murad> ;Anesthesiology Research and Practice. 2020 May 8
8 citations
Machine learning in data abstraction: A computable phenotype for sepsis and septic shock diagnosis in the intensive care unit
Prabij Dhungana, Laura Piccolo Serafim, Arnaldo Lopez Ruiz, Danette L. Bruns, Timothy J. Weister, Nathan J. Smischney, Rahul Kashyap> ;World Journal of Critical Care Medicine. 2019 Nov 19
36 citations
Anticoagulation with direct thrombin inhibitors during extracorporeal membrane oxygenation.
Barry Burstein, Patrick M. Wieruszewski, Yan-Jun Zhao, Nathan J. Smischney> ;World Journal of Critical Care Medicine. 2019 Oct 16
22 citations
Ketamine/propofol admixture vs etomidate for intubation in the critically ill: KEEP PACE Randomized clinical trial.
Nathan J. Smischney, Wayne T. Nicholson, Daniel R. Brown, Alice Gallo De Moraes, Sumedh S. Hoskote, Brian W. Pickering, Richard A. Oeckler, Vivek N. Iyer, Ognjen Gajic...> ;The Journal of Trauma and Acute Care Surgery. 2019 Apr 1
8 citations
The Incidence of and Risk Factors for Postintubation Hypotension in the Immunocompromised Critically Ill Adult.
Nathan J. Smischney, Mohamed O. Seisa, John Cambest, Robert A. Wiegand, Kyle D. Busack, Theodore O. Loftsgard, Darrell R. Schroeder, Daniel A. Diedrich> ;Journal of Intensive Care Medicine. 2019 Jul 1
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