NeilDGrahamMD

PubMed

• 41 citations
  Olfactory Outcomes with Dupilumab in Chronic Rhinosinusitis with Nasal Polyps.
  Joaquim Mullol, Claus Bachert, Nikhil Amin, Martin Desrosiers, Peter Hellings, Joseph K. Han, Roger Jankowski, Jan Vodička, Philippe Gevaert, Nadia Daizadeh, Asif H. K...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2021 Oct 7
• 50 citations
  Baseline FeNO as a prognostic biomarker for subsequent severe asthma exacerbations in patients with uncontrolled, moderate-to-severe asthma receiving placebo in the LI...
  William W. Busse, Sally E. Wenzel, Thomas B. Casale, J. Mark FitzGerald, Megan S. Rice, Nadia Daizadeh, Yamo Deniz, Naimish Patel, Sivan Harel, Paul Rowe, Neil M.H. Gr...> ;The Lancet. Respiratory Medicine. 2021 Oct 1
• 67 citations
  Dupilumab suppresses type 2 inflammatory biomarkers across multiple atopic, allergic diseases.
  Jennifer D. Hamilton, Sivan Harel, Brian N. Swanson, William Brian, Zhen Chen, Megan S. Rice, Nikhil Amin, Marius Ardeleanu, Allen Radin, Brad Shumel, Marcella Ruddy, ...> ;Clinical and Experimental Allergy. 2021 Jul 1
• 10 citations
  Dupilumab efficacy in adolescents with uncontrolled, moderate-to-severe asthma: LIBERTY ASTHMA QUEST.
  Jorge Maspero, JM FitzGerald, Ian D. Pavord, Megan S. Rice, Jaman Maroni, Paul Rowe, Gianluca Pirozzi, Nikhil Amin, Marcella Ruddy, Neil M.H. Graham, Ariel Teper, Mega...> ;Allergy. 2021 May 10
• 27 citations
  Dupilumab Improves Asthma and Sinonasal Outcomes in Adults with Moderate-to-Severe Atopic Dermatitis.
  Mark Boguniewicz, Lisa A. Beck, Lawrence Sher, Emma Guttman-Yassky, Diamant Thaçi, Andrew Blauvelt, Margitta Worm, Jonathan Corren, Weily Soong, Peter A. Lio, Ana B. R...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2021 Mar 1
• 45 citations
  Dupilumab improves upper and lower airway disease control in chronic rhinosinusitis with nasal polyps and asthma.
  Tanya M. Laidlaw, Claus Bachert, Nikhil Amin, Martin Desrosiers, Peter Hellings, Joaquim Mullol, Jorge Maspero, Philippe Gevaert, M. Zhang, Xuezhou Mao, Asif H. Khan, ...> ;Annals of Allergy, Asthma & Immunology. 2021 May 1
• 28 citations
  Conjunctivitis in Dupilumab Clinical Trials for Adolescents with Atopic Dermatitis or Asthma
  Ashish Bansal, Eric L. Simpson, Amy S. Paller, Elaine C. Siegfried, Andrew Blauvelt, Marjolein S. de Bruin-Weller, Jonathan Corren, Lawrence Sher, Emma Guttman-Yassky,...> ;American Journal of Clinical Dermatology. 2021 Jan 1
• 13 citations
  Dupilumab Efficacy in Patients Stratified by Baseline Treatment Intensity and Lung Function.
  Ian D. Pavord, Salman Siddiqui, Alberto Papi, Jonathan Corren, Lawrence Sher, Philip G. Bardin, David Langton, Hae-Sim Park, Megan S. Rice, Yamo Deniz, Paul Rowe, Heri...> ;Journal of Asthma and Allergy. 2020 Dec 16
• 3 citations
  Dupilumab Significantly Modulates Pain and Discomfort in Patients With Atopic Dermatitis: A Post Hoc Analysis of 5 Randomized Clinical Trials.
  Jonathan I. Silverberg, Eric L. Simpson, Emma Guttman-Yassky, Michael J. Cork, Marjolein S. de Bruin-Weller, Gil Yosipovitch, Laurent Eckert, Zhen Chen, Marius Ardelea...> ;Dermatitis. 2021 Oct 1
• 154 citations
  Efficacy and safety of dupilumab with concomitant topical corticosteroids in children 6 to 11 years old with severe atopic dermatitis: A randomized, double-blinded, pl...
  Amy S. Paller, Elaine C. Siegfried, Diamant Thaçi, Andreas Wollenberg, Michael J. Cork, Peter D. Arkwright, Melinda Gooderham, Lisa A. Beck, Mark Boguniewicz, Lawrence...> ;Journal of the American Academy of Dermatology. 2020 Nov 1
• 9 citations
  Base and Covariate Population Pharmacokinetic Analyses of Dupilumab Using Phase 3 Data.
  Pavel Kovalenko, John D. Davis, Meng Li, Ronda Rippley, Marius Ardeleanu, Brad Shumel, Neil M.H. Graham, Gianluca Pirozzi, Mohamed A. Kamal, A. Thomas DiCioccio> ;Clinical Pharmacology in Drug Development. 2020 Aug 1
• 55 citations
  Dupilumab Provides Favorable Safety and Sustained Efficacy for up to 3 Years in an Open-Label Study of Adults with Moderate-to-Severe Atopic Dermatitis.
  Lisa A. Beck, Diamant Thaçi, Mette Deleuran, Andrew Blauvelt, Robert Bissonnette, Marjolein S. de Bruin-Weller, Michihiro Hide, Lawrence Sher, Iftikhar Hussain, Zhen C...> ;American Journal of Clinical Dermatology. 2020 Aug 1
• 60 citations
  Dupilumab treatment results in early and sustained improvements in itch in adolescents and adults with moderate to severe atopic dermatitis: Analysis of the randomized...
  Jonathan I. Silverberg, Gil Yosipovitch, Eric L. Simpson, Brian S. Kim, Jashin J. Wu, Laurent Eckert, Isabelle Guillemin, Zhen Chen, Marius Ardeleanu, Ashish Bansal, M...> ;Journal of the American Academy of Dermatology. 2020 Jun 1
• 25 citations
  Efficacy of dupilumab on clinical outcomes in patients with asthma and perennial allergic rhinitis.
  William W. Busse, Jorge Maspero, Yufang Lu, Jonathan Corren, Nicola A. Hanania, Bradley E. Chipps, Constance H. Katelaris, J. Mark FitzGerald, Santiago Quirce, Linda B...> ;Annals of Allergy, Asthma & Immunology. 2020 May 28
• 13 citations
  Dupilumab efficacy and safety in Japanese patients with uncontrolled, moderate-to-severe asthma in the phase 3 LIBERTY ASTHMA QUEST study.
  Yuji Tohda, Yoichi Nakamura, Takao Fujisawa, Motohiro Ebisawa, Kazuhiko Arima, Masanori Miyata, Yoshinori Takahashi, Megan S. Rice, Yamo Deniz, Paul Rowe, Naimish Pate...> ;Allergology International. 2020 Oct 1
• 24 citations
  Association of High Serum Interleukin‐6 Levels With Severe Progression of Rheumatoid Arthritis and Increased Treatment Response Differentiating Sarilumab From Adalimum...
  Anita Boyapati, Sergio Schwartzman, Jerome Msihid, Ernest Choy, Mark C. Genovese, Gerd R Burmester, Gordon K Lam, Toshio Kimura, Jonathan Sadeh, David M. Weinreich, Ge...> ;Arthritis & Rheumatology. 2020 Apr 28
• 20 citations
  Sarilumab and adalimumab differential effects on bone remodelling and cardiovascular risk biomarkers, and predictions of treatment outcomes
  Cem Gabay, Gerd R Burmester, Vibeke Strand, Jerome Msihid, Zilberstein Moshe E, Toshio Kimura, Hubert van Hoogstraten, Susan Boklage, Jonathan Sadeh, Neil M.H. Graham,...> ;Arthritis Research & Therapy. 2020 Apr 7
• 13 citations
  Sarilumab monotherapy or in combination with non-methotrexate disease-modifying antirheumatic drugs in active rheumatoid arthritis: A Japan phase 3 trial (HARUKA).
  Hideto Kameda, Kazuteru Wada, Yoshinori Takahashi, Owen Hagino, Hubert van Hoogstraten, Neil M.H. Graham, Yoshiya Tanaka> ;Modern Rheumatology. 2020 Mar 3
• 33 citations
  Dupilumab Efficacy in Uncontrolled, Moderate-to-Severe Asthma with Self-Reported Chronic Rhinosinusitis
  Jorge Maspero, Constance H. Katelaris, William W. Busse, Mario Castro, Jonathan Corren, Bradley E. Chipps, Anju T. Peters, Ian D. Pavord, Linda B. Ford, Lawrence Sher,...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2020 Feb 1
• 117 citations
  Dupilumab Shows Long-Term Safety and Efficacy in Patients With Moderate to Severe Atopic Dermatitis Enrolled in a Phase 3 Open-Label Extension Study
  Mette Deleuran, Diamant Thaçi, Lisa A. Beck, Marjolein S. de Bruin-Weller, Andrew Blauvelt, Seth Forman, Robert Bissonnette, Kristian Reich, Weily Soong, Iftikhar Huss...> ;Journal of the American Academy of Dermatology. 2020 Feb 1
• 99 citations
  Dupilumab Efficacy in Patients with Uncontrolled, Moderate-to-Severe Allergic Asthma.
  Jonathan Corren, Mario Castro, Thomas G. O'Riordan, Nicola A. Hanania, Ian D. Pavord, Santiago Quirce, Bradley E. Chipps, Sally E. Wenzel, Karthinathan Thangavelu, Meg...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2020 Feb 1
• 43 citations
  Clinically Meaningful Responses to Dupilumab in Adolescents with Uncontrolled Moderate-to-Severe Atopic Dermatitis: Post-hoc Analyses from a Randomized Clinical Trial
  Amy S. Paller, Ashish Bansal, Eric L. Simpson, Mark Boguniewicz, Andrew Blauvelt, Elaine C. Siegfried, Emma Guttman-Yassky, Thomas Hultsch, Zhen Chen, Paola Mina-Osori...> ;American Journal of Clinical Dermatology. 2020 Feb 1
• 82 citations
  Efficacy and Safety of Multiple Dupilumab Dose Regimens After Initial Successful Treatment in Patients With Atopic Dermatitis: A Randomized Clinical Trial.
  Margitta Worm, Eric L. Simpson, Diamant Thaçi, Robert Bissonnette, Jean-Philippe Lacour, Stefan Beissert, M. Kawashima, Carlos Ferrándiz, Catherine H. Smith, Lisa A. B...> ;JAMA Dermatology. 2020 Feb 1
• 108 citations
  IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis.
  Chris Callewaert, Teruaki Nakatsuji, Rob Knight, Tomasz Kosciolek, Alison Vrbanac, Paul Kotol, Marius Ardeleanu, Thomas Hultsch, Emma Guttman-Yassky, Robert Bissonnett...> ;The Journal of Investigative Dermatology. 2020 Jan 1
• 53 citations
  Dupilumab improves health-related quality of life in patients with chronic rhinosinusitis with nasal polyposis.
  Claus Bachert, Peter Hellings, Joaquim Mullol, Daniel L. Hamilos, P. Gevaert, Robert M. Naclerio, Vijay N. Joish, Jingdong Chao, Leda Mannent, Nikhil Amin, Adeline Abb...> ;Allergy. 2020 Jan 1
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Journal Articles

• Dupilumab Reduces Severe Exacerbation Rate and Improves Lung Function in Adolescent Patients with Uncontrolled, Moderate-to-Severe Asthma: From the Liberty Asthma Ques...  
  Sally Wenzel, Neil Graham, Jaman Maroni, Nikhil Amin, Maspero J, Fitzgerald M, Pavord I, et al.