NorahLynnHenryMDPhD

Oncology • Ann Arbor, MI

Breast Cancer

Associate Professor

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Office
1500 E Medical Center Dr
Ann Arbor, MI 48109
Phone+1 734-936-6000
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Education & Training

University of Michigan Health SystemFellowship, Hematology and Medical Oncology, 2004 - 2007
Brigham and Women's HospitalResidency, Internal Medicine, 2001 - 2004
Washington University in St. Louis School of MedicineClass of 2001
Stanford UniversityPhD, Structural Biology, 1991 - 1996

Certifications & Licensure

MI State Medical License 2004 - 2026
UT State Medical License 2016 - 2020
MA State Medical License 2002 - 2005
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Clinical Trials

Aromatase Inhibitors in Premenopausal Breast Cancer Patients With Chemotherapy-Induced Ovarian Failure Start of enrollment: 2007 Aug 01
Terminated
Phase 2
A Pilot Observational Study to Assess Changes in Biochemical Parameters of Ovarian Reserve With Chemotherapy Start of enrollment: 2007 Sep 01
Completed
Study to Assess Effect of 8 Wks of Duloxetine Therapy on Breast Cancer Patients With Aromatase-Inhibitor Associated Pain Start of enrollment: 2008 Oct 01
Completed
Not Applicable
S1202: Duloxetine Hydrochloride for Muscle/Joint Pain in Early-Stage Breast Cancer Receiving Hormone Therapy Start of enrollment: 2013 May 15
Completed
Phase 3
Pilot Study to Evaluate the Effect of Aromatase Inhibitor Therapy on Pain Threshold in Breast Cancer Patients Start of enrollment: 2009 Jul 01
Completed
Loss of Grip Strength, BMI, and Adjuvant Endocrine Therapy Breast Cancer Start of enrollment: 2009 Sep 01
Completed
Mechanistic Study of Duloxetine in Breast Cancer Patients With Chronic Pain Start of enrollment: 2013 Oct 30
Completed
Phase 2
Pilot Study of Cyclobenzaprine for Treatment of Sleep Disturbance in Aromatase Inhibitor-treated Breast Cancer Patients Start of enrollment: 2013 Aug 01
Terminated
Phase 2
A Study Evaluating Talazoparib (BMN 673), a PARP Inhibitor, in Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (EMBRACA Study) Start of enrollment: 2013 Oct 14
Completed
Phase 3
Effect of Chemotherapy on Pain Sensitivity and Patient-reported Symptoms Start of enrollment: 2013 Nov 01
Completed
Examining the Relationships Between Sleep, Fatigue, and Pain in Aromatase Inhibitor-treated Patients Start of enrollment: 2013 Nov 01
Completed
Study of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast Cancer Start of enrollment: 2013 Nov 01
Completed
Phase 2
Observational Study to Evaluate Mechanisms of Aromatase Inhibitor Associated Musculoskeletal Symptoms Start of enrollment: 2009 Oct 01
Completed
Pilot Functional Imaging Study to Evaluate Mechanisms Underlying Chronic Pain in Breast Cancer Patients Start of enrollment: 2012 Mar 01
Tissue Procurement Protocol for Patients Undergoing Treatment for Early-Stage Breast Cancer Start of enrollment: 2014 May 30
Terminated
Imaging Biomarker for Early Detection of Treatment Efficacy During Breast Cancer Neoadjuvant Chemotherapy Start of enrollment: 2006 Jun 01
Completed
Early Phase 1
Prospective Study Evaluating the Use of PROSPECT to Reduce Insomnia in Patients With Early Stage Breast Cancer Start of enrollment: 2016 Mar 16
Terminated
Not Applicable
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Publications & Presentations

PubMed

Dynamic Risk Prediction of Treatment Discontinuation Using Patient-Reported Outcomes Data in the Phase III NSABP B-35 Trial.
Vinicius F Calsavara, Norah L Henry, Ron D Hays, Sungjin Kim, Michael Luu, Márcio A Diniz, Gillian Gresham, Reena S Cecchini, Greg Yothers, Patricia A Ganz, André Roga...> ;Cancer Prevention Research. 2023 Nov 1
Toxicity Index, patient-reported outcomes, and persistence of breast cancer chemotherapy-associated side effects in NRG Oncology/NSABP B-30.
N Lynn Henry, Sungjin Kim, Ron D Hays, Marcio A Diniz, Mourad Tighiouart, Gillian Gresham, Michael Luu, Reena S Cecchini, Greg Yothers, André Rogatko, Patricia A Ganz> ;NPJ Breast Cancer. 2022 Nov 19
Association between nociplastic pain and premature endocrine therapy discontinuation in breast cancer patients.
Elizabeth Joyce, Grant Carr, Sidi Wang, Chad M Brummett, Kelley M Kidwell, N Lynn Henry> ;Breast Cancer Research and Treatment. 2023 Jan 1
14 citations
Inclusion of a core patient-reported outcomes battery in adolescent and young adult cancer clinical trials.
Michael E Roth, Susan K Parsons, Patricia A Ganz, Lynne I Wagner, Pamela S Hinds, Sarah Alexander, Kristin Bingen, Sharon L Bober, Julienne Brackett, David Cella, N Ly...> ;Journal of the National Cancer Institute. 2023 Jan 10
Simulation study comparing analytical methods for single-item longitudinal patient-reported outcomes data.
Vinicius F Calsavara, Márcio A Diniz, Mourad Tighiouart, Patricia A Ganz, N Lynn Henry, Ron D Hays, Greg Yothers, André Rogatko> ;Quality of Life Research. 2023 Mar 1
14 citations
NCCN Guidelines® Insights: Survivorship, Version 1.2022.
Tara Sanft, Andrew Day, Lindsay Peterson, M Alma Rodriguez, Shannon Ansbaugh, Saro Armenian, K Scott Baker, Tarah Ballinger, Gregory Broderick, Wendy Demark-Wahnefried...> ;Journal of the National Comprehensive Cancer Network. 2022 Oct 1
3 citations
A Multimodal Approach to Discover Biomarkers for Taxane-Induced Peripheral Neuropathy (TIPN): A Study Protocol.
Anukriti Sharma, Ken B Johnson, Bihua Bie, Emily E Rhoades, Alper Sen, Yuri Kida, Jennifer Hockings, Alycia Gatta, Jacqueline Davenport, Connie Arcangelini, Jennifer R...> ;Technology in Cancer Research & Treatment. 2022 Sep 29
1 citations
Unintended Negative Consequences of Managing Chemotherapy Toxicity.
N Lynn Henry, Patricia A Ganz> ;Journal of the National Cancer Institute. 2022 Dec 8
2 citations
Biomarkers for Systemic Therapy in Metastatic Breast Cancer: ASCO Guideline Update Q and A.
Amy S Clark, Erin F Cobain, Zoneddy Dayao, Mark R Somerfield, Angela DeMichele, N Lynn Henry> ;JCO Oncology Practice. 2022 Dec 1
Co-occurrence and metabolic biomarkers of sensory and motor subtypes of peripheral neuropathy from paclitaxel.
Ciao-Sin Chen, Ellen M Lavoie Smith, Kathleen A Stringer, N Lynn Henry, Daniel L Hertz> ;Breast Cancer Research and Treatment. 2022 Aug 1
1 citations
Factors influencing scalp cooling discussions and use at a large academic institution: a single-center retrospective review.
Taylor Novice, David Portney, Joshua Goyert, N Lynn Henry, Jacqueline S Jeruss, Monika L Burness, Madison Novice> ;Supportive Care in Cancer. 2022 Oct 1
2 citations
Genome-wide association study of aromatase inhibitor discontinuation due to musculoskeletal symptoms.
Daniel L Hertz, Julie A Douglas, Robert M Miller, Kelley M Kidwell, Christina L Gersch, Zeruesenay Desta, Anna Maria Storniolo, Vered Stearns, Todd C Skaar, Daniel F H...> ;Supportive Care in Cancer. 2022 Oct 1
2 citations
Muscle mass affects paclitaxel systemic exposure and may inform personalized paclitaxel dosing.
Daniel L Hertz, Li Chen, N Lynn Henry, Jennifer J Griggs, Daniel F Hayes, Brian A Derstine, Grace L Su, Stewart C Wang, Manjunath P Pai> ;British Journal of Clinical Pharmacology. 2022 Jul 1
28 citations
Biomarkers for Systemic Therapy in Metastatic Breast Cancer: ASCO Guideline Update.
N Lynn Henry, Mark R Somerfield, Zoneddy Dayao, Anthony Elias, Kevin Kalinsky, Lisa M McShane, Beverly Moy, Ben Ho Park, Kelly M Shanahan, Priyanka Sharma, Rebecca Sha...> ;Journal of Clinical Oncology. 2022 Sep 20
105 citations
Biomarkers for Adjuvant Endocrine and Chemotherapy in Early-Stage Breast Cancer: ASCO Guideline Update.
Fabrice Andre, Nofisat Ismaila, Kimberly H Allison, William E Barlow, Deborah E Collyar, Senthil Damodaran, N Lynn Henry, Komal Jhaveri, Kevin Kalinsky, Nicole M Kuder...> ;Journal of Clinical Oncology. 2022 Jun 1
6 citations
Survey of US Medical Oncologists' Practices and Beliefs RegardingTesting Before Fluoropyrimidine Chemotherapy.
Kyoin Koo, Amy L Pasternak, N Lynn Henry, Vaibhav Sahai, Daniel L Hertz> ;JCO Oncology Practice. 2022 Jun 1
2 citations
Cardiovascular disease risk in long-term breast cancer survivors: A population-based cohort study.
Alzina Koric, Chun-Pin Chang, Bayarmaa Mark, Kerry Rowe, John Snyder, Mark Dodson, Vikrant G Deshmukh, Michael G Newman, Alison M Fraser, Ken R Smith, Ankita P Date, L...> ;Cancer. 2022 Jul 15
74 citations
Sex Differences in Risk of Severe Adverse Events in Patients Receiving Immunotherapy, Targeted Therapy, or Chemotherapy in Cancer Clinical Trials.
Joseph M Unger, Riha Vaidya, Kathy S Albain, Michael LeBlanc, Lori M Minasian, Carolyn C Gotay, N Lynn Henry, Michael J Fisch, Shing M Lee, Charles D Blanke, Dawn L He...> ;Journal of Clinical Oncology. 2022 May 1
21 citations
Immune Checkpoint Inhibitors and Risk of Type 1 Diabetes.
Xuan Chen, Alison H Affinati, Yungchun Lee, Adina F Turcu, Norah Lynn Henry, Elena Schiopu, Angel Qin, Megan Othus, Dan Clauw, Nithya Ramnath, Lili Zhao> ;Diabetes Care. 2022 May 1
Evaluating the Association of Adverse Events and Patient-Reported Symptoms to Endocrine Therapy Tolerability.
N Lynn Henry, André Rogatko, Patricia A Ganz> ;Journal of Clinical Oncology. 2022 Feb 1
Predictors of Pain Reduction in Trials of Interventions for Aromatase Inhibitor-Associated Musculoskeletal Symptoms
N. Lynn Henry, Joseph M. Unger, Cathee Till, Katherine D. Crew, Michael J. Fisch, Dawn L. Hershman> ;JNCI Cancer Spectrum. 2021 Oct 30
6 citations
SWOG 1918: A phase II/III randomized study of R-miniCHOP with or without oral azacitidine (CC-486) in participants age 75 years or older with newly diagnosed aggressiv...
Elizabeth Brem, Hongli Li, Anne W. Beaven, Paolo F. Caimi, Leandro Cerchietti, Ash A. Alizadeh, Rebecca L. Olin, N. Lynn Henry, Hildy Dillon, Richard F. Little, Cara L...> ;Journal of Geriatric Oncology. 2021 Oct 19
3 citations
Toxicity Index, Patient-Reported Outcomes, and Early Discontinuation of Endocrine Therapy for Breast Cancer Risk Reduction in NRG Oncology/NSABP B-35
N. Lynn Henry, Sungjin Kim, Ron D. Hays, Marcio A. Diniz, Michael Luu, Reena S. Cecchini, Greg Yothers, Andre Rogatko, Patricia A. Ganz> ;Journal of Clinical Oncology. 2021 Sep 23
1 citations
Identifying Barriers and Facilitators to Scalp Cooling Therapy Through a National Survey of the Awareness, Practice Patterns, and Attitudes of Oncologists
Taylor Novice, N. Lynn Henry, Kyle Johnson, Jacqueline S. Jeruss, Kelley M. Kidwell, Monika L. Burness, Madison L. Novice> ;JCO Oncology Practice. 2021 Sep 16
2 citations
Genome-wide association study of letrozole plasma concentrations identifies non-exonic variants that may affect CYP2A6 metabolic activity.
Daniel L. Hertz, Julie A. Douglas, Kelley M. Kidwell, Christina L. Gersch, Zeruesenay Desta, Ana Maria Storniolo, Vered Stearns, Todd C. Skaar, Daniel F. Hayes, N. Lyn...> ;Pharmacogenetics and Genomics. 2021 Jul 1
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Lectures

Mindfulness and concerns about adjuvant endocrine therapy (AET).
2019 ASCO Annual Meeting - 6/1/2019

Press Mentions

A Complete Guide to the Five Stages of Breast Cancer and How to Recognize Each StageNovember 8th, 2021
New Research on Treating Hormone Receptor-Positive Breast Cancer from SABCS 2020January 29th, 2021
Why Supporting the Fight Against Breast Cancer Is More Important Than Ever This YearOctober 26th, 2020
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