ObaidShakilShaikhMD

PubMed

• Nirmatrelvir/Ritonavir Use and Hospitalizations or Death in a Previously Uninfected Nonhospitalized High-Risk Population With COVID-19: A Matched Cohort Study.
  Adeel A Butt, Peng Yan, Obaid S Shaikh, Victor B Talisa, Saad B Omer, Florian B Mayr> ;The Journal of Infectious Diseases. 2024 Jan 12
• 3 citations
  Molnupiravir Use and 30-Day Hospitalizations or Death in a Previously Uninfected Nonhospitalized High-risk Population With COVID-19.
  Adeel A Butt, Peng Yan, Obaid S Shaikh, Saad B Omer, Florian B Mayr, Victor B Talisa> ;The Journal of Infectious Diseases. 2023 Oct 18
• 13 citations
  Relative Vaccine Effectiveness of a Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine Booster Dose Against the Omicron Variant.
  Adeel A Butt, Victor B Talisa, Obaid S Shaikh, Saad B Omer, Florian B Mayr> ;Clinical Infectious Diseases. 2022 Dec 19
• 5 citations
  Variation in Clinical Treatment and Outcomes by Race Among US Veterans Hospitalized With COVID-19.
  Alexander D Castro, Florian B Mayr, Victor B Talisa, Obaid S Shaikh, Saad B Omer, Sachin Yende, Adeel A Butt> ;JAMA Network Open. 2022 Oct 3
• 16 citations
  Rate and Risk Factors for Severe/Critical Disease Among Fully Vaccinated Persons With Breakthrough Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infecti...
  Adeel A Butt, Peng Yan, Obaid S Shaikh, Florian B Mayr, Saad B Omer> ;Clinical Infectious Diseases. 2022 Aug 24
• 13 citations
  Vaccine Effectiveness of 3 Versus 2 Doses of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA Vaccines in a High-Risk National Population.
  Adeel A Butt, Victor B Talisa, Peng Yan, Obaid S Shaikh, Saad B Omer, Florian B Mayr> ;Clinical Infectious Diseases. 2022 Aug 24
• 2 citations
  Real-World Effectiveness of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA Vaccines in Preventing Confirmed Infection in Patients on Chronic Hem...
  Adeel A Butt, Victor B Talisa, Peng Yan, Obaid S Shaikh, Saad B Omer, Florian B Mayr> ;Clinical Infectious Diseases. 2022 Aug 24
• 8 citations
  Comparative COVID-19 Vaccine Effectiveness Over Time in Veterans.
  Florian B Mayr, Victor B Talisa, Obaid S Shaikh, Saad B Omer, Adeel A Butt, Sachin Yende> ;Open Forum Infectious Diseases. 2022 Jul 1
• 22 citations
  COVID-19 disease severity in US Veterans infected during Omicron and Delta variant predominant periods.
  Florian B Mayr, Victor B Talisa, Alexander D Castro, Obaid S Shaikh, Saad B Omer, Adeel A Butt> ;Nature Communications. 2022 Jun 25
• 34 citations
  Effectiveness of Homologous or Heterologous Covid-19 Boosters in Veterans.
  Florian B Mayr, Victor B Talisa, Obaid Shaikh, Sachin Yende, Adeel A Butt> ;The New England Journal of Medicine. 2022 Apr 7
• 20 citations
  Outcomes among patients with breakthrough SARS-CoV-2 infection after vaccination in a high-risk national population.
  Adeel A. Butt, Peng Yan, Obaid S. Shaikh, Florian B. Mayr> ;Eclinicalmedicine. 2021 Aug 28
• 65 citations
  SARS-CoV-2 Vaccine Effectiveness in a High-Risk National Population in a Real-World Setting.
  Adeel A. Butt, Saad B. Omer, Peng Yan, Obaid S. Shaikh, Florian B. Mayr> ;Annals of Internal Medicine. 2021 Jul 20
• 25 citations
  Mortality is not increased in SARS-CoV-2 infected persons with hepatitis C virus infection.
  Adeel A. Butt, Peng Yan, Rashid A Chotani, Obaid S. Shaikh> ;Liver International. 2021 Feb 3
• 34 citations
  Rate and Risk Factors for Breakthrough SARS-CoV-2 infection After Vaccination.
  Adeel A. Butt, Tasnim Khan, Peng Yan, Obaid S. Shaikh, Saad B. Omer, Florian B. Mayr> ;The Journal of Infection. 2021 Jan 1
• 2 citations
  Spontaneous Regression of Advanced Hepatocellular Carcinoma.
  Dhiraj J Sonbare, Rupal Bandi, Vivek Sharma, Thomas V. Cacciarelli, Obaid S. Shaikh> ;Case Reports in Gastroenterology. 2020 Oct 15
• 10 citations
  Precore and Basal Core Promoter Hepatitis B Virus (HBV) Variants Are Present From a Young Age and Differ Across HBV Genotypes.
  Daryl T.-Y. Lau, Lilia Ganova-Raeva, Junyao Wang, Douglas Mogul, Raymond T. Chung, Mauricio Lisker-Melman, Kyong-Mi Chang, Obaid S. Shaikh, Harry L.A. Janssen, Abdus S...> ;Hepatology. 2021 May 1
• 28 citations
  Treatment of HCV reduces viral hepatitis-associated liver-related mortality in patients: An ERCHIVES study.
  Adeel A. Butt, Peng Yan, Obaid S. Shaikh, Vincent Lo Re, Abdul-Badi Abou-Samra, Kenneth E. Sherman> ;Journal of Hepatology. 2020 Aug 1
• 7 citations
  Liver Fibrosis Progression and Mortality in Hepatitis B– and C–Coinfected Persons Treated With Directly Acting Antiviral Agents: Results From ERCHIVES
  Adeel A. Butt, Peng Yan, Samia Aslam, Abdul-Badi Abou-Samra, Kenneth E. Sherman, Obaid S. Shaikh> ;Clinical Infectious Diseases. 2020 Jul 27
• 11 citations
  Provider Perceptions of Hepatitis C Treatment Adherence and Initiation
  Grace Zhang, Krupa Patel, Akshata Moghe, Andrea Reid, Marina Serper, Linda Calgaro, Sandra Gibson, Susan Zickmund, Obaid S. Shaikh, Shari S. Rogal> ;Digestive Diseases and Sciences. 2020 May 1
• 3 citations
  Deferred treatment with a fixed-dose combination of sofosbuvir-velpatasvir for chronic hepatitis C virus genotype 1, 2, 4 and 6 infection.
  Tarik Asselah, Stephen D. Shafran, Suzanne Bourgeois, Ching-Lung Lai, Philippe Mathurin, Bernard Willems, Mindie H. Nguyen, M. Davis, K.C. Huang, Evguenia S. Svarovska...> ;Journal of Viral Hepatitis. 2019 Oct 1
• 2 citations
  Liver Transplant From Increased-Risk Donors in the Era of Direct-Acting Antivirals for Hepatitis C.
  Obaid S. Shaikh, Shari S. Rogal, Anam Malik, Vivek Sharma, Thomas V. Cacciarelli> ;Experimental and Clinical Transplantation. 2020 Oct 1
• 29 citations
  Hepatitis C Virus (HCV) Treatment With Directly Acting Agents Reduces the Risk of Incident Diabetes: Results From Electronically Retrieved Cohort of HCV Infected Veter...
  Adeel A. Butt, Peng Yan, Samia Aslam, Obaid S Shaikh, Abdul-Badi Abou-Samra> ;Clinical Infectious Diseases. 2019 Apr 12
• 11 citations
  Trends in Treatment Uptake and Provider Specialty for Hepatitis C Virus (HCV) Infection in the Veterans Affairs Healthcare System: Results From the Electronically Retr...
  Adeel A. Butt, Peng Yan, Vincent Lo Re, Obaid S Shaikh, David B Ross> ;Clinical Infectious Diseases. 2019 Feb 15
• 87 citations
  Direct-Acting Antiviral Therapy for HCV Infection Is Associated With a Reduced Risk of Cardiovascular Disease Events
  Adeel A. Butt, Peng Yan, Ashfaq Shuaib, Abdul-Badi Abou-Samra, Obaid S. Shaikh, Matthew S. Freiberg> ;Gastroenterology. 2019 Mar 1
• 124 citations
  The short-term incidence of hepatocellular carcinoma is not increased after hepatitis C treatment with direct-acting antivirals: An ERCHIVES study.
  Darrick K. Li, Yanjie Ren, Daniel S. Fierer, Stephanie M. Rutledge, Obaid S. Shaikh, Vincent Lo Re, Tracey G. Simon, Abdul-Badi Abou-Samra, Raymond T. Chung, Adeel A. ...> ;Hepatology. 2018 Jun 1
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Journal Articles

• Trends in Treatment Uptake and Provider Specialty for HCV Infection in the VA Healthcare System: Results from ERCHIVES  
  Obaid S Shaikh, Adeel A Butt, Clinical Infectious Diseases
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  Terrault N, Reddy R, Poordad F, Curry M, Schiano T , Shaikh O, Dove L, Shetty K, Millis M, Schiff E, Regenstein F, Barnes D, Barin B, Peters M, Roland M, Stock P for t..., Am J Transpl, 5/1/2014
• Steroid use in acute liver failure  
  Karkhanis J, Verna EC, Chang MS, Stravitz RT, Schilsky M, Lee WM, Brown RS Jr; Acute Liver Failure Study Group, Hepatology, 2/1/2014
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  Court MH, Peter I, Hazarika S, Vasiadi M, Greenblatt DJ, Lee WM; Acute Liver Failure Study Group, Drug Metab Dispos, 1/1/2014
• Management of chronic hepatitis C in cirrhosis and liver transplant population  
  Habib S, Shaikh OS, N A J Med Sci, 1/1/2014
• Interferon Treatment Improves Survival among Liver Transplant Recipients with Recurrent Hepatitis C  
  J Surgery, 9/1/2013
• Telaprevir for previously untreated chronic hepatitis C virus infection  
  Jacobson IM, McHutchison JG, Dusheiko G, Di Bisceglie AM, Reddy KR, Bzowej NH, Marcellin P, Muir AJ, Ferenci P, Flisiak R, George J, Rizzetto M, Shouval D, Sola R, Ter..., N Engl J Med, 6/1/2011
• Telaprevir for previously treated chronic HCV infection  
  McHutchison JG, Manns MP, Muir AJ, Terrault NA, Jacobson IM, Afdhal NH, Heathcote EJ, Zeuzem S, Reesink HW, Garg J, Bsharat M, George S, Kauffman RS, Adda N, Di Bisceg..., N Engl J Med, 4/1/2010
• Outcome of acute liver failure in the elderly  
  Schiodt FV, Chung RT, Schilsky ML, Hay JE, Christensen E, Lee WM; Acute Liver Failure Study Group, LiverTranspl, 11/1/2009
• Outcome after liver transplantation for NASH cirrhosis  
  Malik SM, de Vera ME, Fontes P, Shaikh OS, Ahmad J, Am J Transplant, 4/1/2009
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  HIV Clin Trials, 1/1/2009
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  Int J Infect Dis, 1/1/2009
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  El Hajj II, Malik SM, Alwakeel HR, Shaikh OS, Sasatomi E, Kandil HM, World J Gastroenterol, 1/1/2009
• False positive acetaminophen concentrations in patients with liver injury  
  Polson J, Wians FH Jr, Orsulak P, Fuller D, Murray NG, Koff JM, Khan AI, Balko JA, Hynan LS, Lee WM; Acute Liver Failure Study Group, Clin Chim Acta, 5/1/2008
• The coagulopathy of acute liver failure and implications for intracranial pressure monitoring  
  Munoz SJ, Rajender Reddy K, Lee W; Acute Liver Failure Study Group, Neurocrit Care, 1/1/2008
• Intensive care of patients with acute liver failure: recommendations of the US Acute Liver Failure Study Group (Recommendations)  
  Stravitz RT, Kramer AH, Davern T, Shaikh AO, Caldwell SH, Mehta RL, Blei AT, Fontana RJ, McGuire BM, Rossaro L, Smith AD, Lee WM; Acute Liver Failure Study Group, Crit Care Med, 11/1/2007
• Idiopathic posttransplantation hepatitis? Editorial  
  Shaikh OS, Demetris AJ, Liver Transpl, 7/1/2007
• Hepatitis B Immune Globulin Review article  
  Habib S, Shaikh OS, Drugs Today, 6/1/2007
• Alloimmune hepatitis following peripheral stem cell transplantation  
  Habib S, Nalesnik MA, Ahmad J, BuchBarker D, Shakil AO, BMT, 5/1/2007
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  Butt AA, Tsevat J, Ahmad J, Shakil AO, Mrus JM, Am J Med Sci, 5/1/2007
• Hepatitis C virus infection following liver transplantation: natural history and treatment Review article  
  Shaikh OS, Medscape, 1/1/2007
• Survival of liver transplant patients coinfected with HIV and HCV is adversely impacted by recurrent hepatitis C  
  de Vera ME, Dvorchik I, Tom K, Eghtesad B, Thai N, Shakil O, Marcos A, Demetris A, Jain A, Fung JJ, Ragni MV, Am J Transplant, 12/1/2006
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  Clin Pharmacol Ther, 9/1/2006
• Comorbid medical and psychiatric conditions and substance abuse in HCV infected persons on dialysis  
  Butt AA, Evans R, Skanderson M, Shakil AO, J Hepatol, 5/1/2006
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  Kesturu GS, Colleton BA, Liu Y, Heath L, Shaikh OS, Rinaldo CR Jr, Shankarappa R, Virology, 5/1/2006
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Books/Book Chapters

• Gastrointestinal and Hepatobiliary Pathophysiology. 
  Chapter: Orthotopic liver transplantation. 
  Shakil AOEditors: Rose S.Fence Creek Publishing, Madison1998

Abstracts/Posters

• AO Shakil, 1st Annual SKMC International Conference, Advances in Medicine and Subspecialties (AIMS), Abu Dhabi, 2/1/2013
• The Role of Hepatitis E Virus infection in Adult American patients with Acute Liver Failure. Poster Presentation
  Fontana RJ, Engle RE, Trivedi S, Scaglione SJ,Shaikh OS, Attar N, Lee WL, Araya V, Purcell RH, Battenhouse H, American Association for the Study of Liver Diseases - 63rd Annual Meeting, Boston, MA, 11/1/2012
• Hepatitis B in North America: Patients screened for the Hepatitis B Research Network (HBRN) Adult Cohort Study. Poster Presentation
  Wong DK & Hepatitis B Research Network, American Association for the Study of Liver Diseases - 63rd Annual Meeting, Boston, MA, 11/1/2012
• Phenotypes of North American children with hepatitis B virus (HBV) infection. Poster Presentation
  Schwarz KB & Hepatitis B Research Network, American Association for the Study of Liver Diseases - 63rd Annual Meeting, Boston, MA, 11/1/2012
• Risk factors for allograft steatosis in patients with recurrent hepatitis C after liver transplantation - poster presentation.
  AO Shakil, American Association for the Study of Liver Diseases - 58th Annual Meeting, San Franscisco, CA, 10/1/2008
• Progression of Fibrosis with Interferon Treatment in Liver Transplant Recipients with Hepatitis C Infection. Poster Presentation
  American Association for the Study of Liver Diseases - 57th Annual Meeting, Boston, MA, 10/1/2006
• Impact of HCV in patient and graft survival in renal transplant recipients. Poster Presentation
  M Morshedi, R Shapiro, J Fung, M Rohaninejad, AO Shakil, American Association for the Study of Liver Diseases - 56th Annual Meeting, San Francisco, CA, 11/1/2005
• Racial disparities in the probability of death on the liver transplant list in the United States. Poster Presentation
  J Behari, V Swaminatha, AO Shakil, J Ahmad, American Association for the Study of Liver Diseases - 56th Annual Meeting, San Francisco, CA, 11/1/2005
• J Behari, V Swaminatha, C Bryce, TV Cacciarelli, AO Shakil, J Ahmad, American Association for the Study of Liver Diseases - 56th Annual Meeting, San Francisco, CA, 11/1/2005
• Viral quasispecies and severity of recurrent hepatitis C. Poster Presentation
  AO Shakil, LF Wang, R Shankarappa, AJ Demetris, CCH Chang, JJ Fung, American Association for the Study of Liver Diseases - 56th Annual Meeting, San Francisco, CA, 11/1/2005
• High Mobility Group B1 matures Dendritic Cells and is a DAMP Elevated in the Serum of Hepatoma Patients with Chronic Hepatitis C Diminishing Following Resection and Or...
  Lotze MT, DeMarco RA, Hovarth K, Gouttefangeas C, Demetris AJ, DeVera ME, Day R, Pereira PL, Shakil O, International Society for Biological Therapy of Cancer - 20th Annual Meeting, Alexandria, VA, 11/1/2005
• A trial of pegylated interferon and ribavirin among liver transplant recipients with hepatitis C: reasons for screening failure and enrollment - poster presentation.
  AO Shakil, S Habib, B Berk, B Eghtesad, A Marcos, JJ Fung, American Association for the Study of Liver Diseases - 55th Annual Meeting, Boston, MA, 10/1/2004
• American Association for the Study of Liver Diseases - 55th Annual Meeting, Boston, MA, 10/1/2004
• MELD as predictor of post-transplantation survival - oral presentation.
  S Habib, I Dvorchik, J Ahmad, K Chopra, P Fontes, A Marcos, JJ Fung, AO Shakil, American Association for the Study of Liver Diseases - 55th Annual Meeting, Boston, MA, 10/1/2004
• The use of alemtuzumab induction and tacrolimus monotherapy in liver transplantation -poster presentation.
  B Eghtesad, A Marcos, J Fung, P Fontes, K Tom, M DeVera, W Marsh, T Gayowski, O Shakil A Demetris, N Murase, T Starzl, American Association for the Study of Liver Diseases - 55th Annual Meeting, Boston, MA, 10/1/2004
• Risk of diabetes mellitus in hepatitis C and HIV infected patients.
  Butt AA, Ahmad J, Wagener M, Singh N, AO Shakil, Infectious Diseases Society of America - 41st Annual Meeting, San Diego, CA, 1/1/2003
• TJ Davern, RS Brown, AO Shakil, RT Stravitz, J Polson, E Lalani, WM Lee, Acute Liver Failure Study Group, American Association for the Study of Liver Diseases - 54th Annual Meeting, Boston, MA, 1/1/2003
• Applicability of MELD scoring system to predict prognosis in patients with acute liver failure - poster presentation.
  C Aydin, B Berk, J J Fung, AO Shakil, American Association for the Study of Liver Diseases - 54th Annual Meeting, Boston, MA, 1/1/2003
• AO Shakil, SHINE Annual Meeting, Orlando, FL, 1/1/2002
• Entecavir significantly reduces viral load in liver transplant recipients failing lamivudine therapy for chronic hepatitis B infection - poster presentation.
  AO Shakil, L Lilly, P Angus, G Gerken, N Thomas, M Jean, S Joshi, European Association for the Study of the Liver- 37th Annual Meeting, Madrid, Spain, 1/1/2002
• AB Jain, RS Kashyap, F Dodson, A Khan, O Shakil, JF Fung, Transplant Joint Meeting, 1/1/2001
• Need for ribavirin dose adjustment in relation to renal function for treatment of HCV infection in post liver transplant patients - poster presentation.
  A Kumar B. Jani, RS Kashttap, A Khan, O Shakil, JJ Fung, American Association for the Study of Liver Diseases - 52nd Annual Meeting, Dallas, TX, 1/1/2001
• J Ahmad, K Weck, AO Shakil, American Association for the Study of Liver Diseases Single Topic Symposium, Chicago, IL, 1/1/2001
• AM Larson, G Ostapowicz, RJ Fontana, O Shakil, WM Lee, Acute Liver Failure Study Group, American Association for the Study of Liver Diseases - 51st Annual Meeting, Dallas, TX, 1/1/2000
• Risk factors and disease severity among US war veterans with chronic hepatitis C - poster presentation.
  AO Shakil, H Vargas, K Gartner, K Downey, American Association for the Study of Liver Diseases - 51st Annual Meeting, Dallas, TX, 1/1/2000
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Lectures

• Management of hepatitis B in 2011 - Invited Speaker. 
  Mercy Medical Center, Baltimore, MD - 9/1/2011
• Acute liver failure - Invited Speaker. 
  Mercy Medical Center, Baltimore, MD - 9/1/2011
• Sepsis in acute liver failure - invited speaker. 
  Karachi, Pakistan - 12/1/2009
• Postgraduate course: Pathophysiology of portal hypertension. 
  Karachi, Pakistan - 12/1/2006
• Postgraduate course: Liver Transplantation: an overview. 
  Karachi, Pakistan - 12/1/2006
• Postgraduate course: Management of the post liver transplant patient. 
  Karachi, Pakistan - 12/1/2006
• Liver transplantation for hepatitis C. 
  Karachi, Pakistan - 12/1/2006
• An overview of liver transplantation. 
  Sindh Institute of Urology and Transplantation (SIUT), Karachi, Pakistan - 12/1/2006
• Update on Liver Transplantation: Hepatitis C - the medical journey. Course Director & Speaker 
  University of Pittsburgh & Thomas E. Starzl Transplantation Institute, Pittsburgh, PA - 10/1/2006
• Liver transplantation candidacy in the MELD era - Speaker. 
  Pittsburgh, PA - 10/1/2006
• Discussant, Clinicopathologic conference. 
  Nagpur, India - 2/1/2006
• Breakfast workshop, Managing fulminant hepatic failure without liver transplantation. 
  Nagpur, India - 2/1/2006
• The marginal graft: assessment, utilization and outcome. 
  Nagpur, India - 2/1/2006
• Hepatitis C pathogenesis: role of viral quasispecies (course director and speaker). 
  12/1/2005
• Liver transplant candidacy in the MELD era (invited speaker). 
  Danville, PA - 11/1/2005
• Impact of obesity, steatosis, diabetes mellitus and hyperinsulinemia on HCV treatment response (invited speaker). 
  Alma Illery Medical Center, Pittsburgh, PA - 11/1/2005
• Consequences of advanced liver disease. 
  Mercy Hospital, Pittsburgh, PA - 10/1/2005
• An update on acute liver failure. 
  Dow Medical University, Karachi, Pakistan - 12/1/2004
• Current strategies for common medical problems: common gastrointestinal problems seen in the primary care office. 
  11/20/2004
• Update in GI and Hepatology, what's new and what to do: advances in hepatitis B. (invited speaker) 
  11/13/2004
• Current perspectives in hepatitis C. 
  UPMC McKeesport, Pittsburgh, PA; Uniontown Hospital, Uniontown - 4/1/2002
• Recent Advances in HCV Therapy: a Specialist's Perspective. (invited lecture) 
  Omni William Penn, Pittsburgh, PA - 1/1/2002
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  Pittsburgh, PA - 1/1/2001
• Overview of Hepatitis C (invited lecture). 
  UPMC Shadyside, Pittsburgh, PA - 1/1/2001
• Recent Advances in Hepatitis C (invited lecture). 
  Marshall University, Huntington, WV - 1/1/2001
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