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Office
8700 Beverly Blvd
Los Angeles, CA 90048- Is this information wrong?
Education & Training
Yale-New Haven Medical CenterResidency, Pediatrics, 2000 - 2003
Yale School of MedicineClass of 2000
Certifications & Licensure
CA State Medical License 2003 - 2025- American Board of Medical Genetics and Genomics Clinical Genetics and Genomics
Awards, Honors, & Recognition
- Fellow (FAAP) American Academy of Pediatrics
Clinical Trials
- Evaluation of Phenotypic and Genetic Properties in Male Subjects Affected by Hypohidrotic Ectodermal Dysplasia - A Start of enrollment: 2011 Feb 01
- A Phase 1, Open-label, Multicenter, Safety and Pharmacokinetic Study of EDI200 Start of enrollment: 2012 May 01
- Phase 2 Study to Evaluate Safety, Pharmacokinetics, Immunogenicity and Pharmacodynamics/Efficacy of EDI200 in Male Infants With X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED) Start of enrollment: 2013 Apr 01
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Publications & Presentations
PubMed
- Sprouty genes regulate activated fibroblasts in mammary epithelial development and breast cancer.Jiyong Li, Rongze Ma, Xuebing Wang, Yunzhe Lu, Jing Chen, Deyi Feng, Jiecan Zhou, Kun Xia, Hao Xie, Pengfei Lu, Ophir Klein> ;Cell Death & Disease. 2024 Apr 10
- 1 citationsProliferation-driven mechanical compression induces signalling centre formation during mammalian organ development.Neha Pincha Shroff, Pengfei Xu, Sangwoo Kim, Elijah R Shelton, Ben J Gross, Yucen Liu, Carlos O Gomez, Qianlin Ye, Tingsheng Yu Drennon, Jimmy K Hu, Jeremy B A Green, ...> ;Nature Cell Biology. 2024 Apr 1
- 2023 ASHG Lifetime Achievement Award: Neil Risch.Ophir Klein> ;American Journal of Human Genetics. 2024 Mar 7
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Journal Articles
- Mechanoresponsive Stem Cells Acquire Neural Crest Fate in Jaw RegenerationRyan C Ransom, Michael L Lopez, Ophir D Klein, Howard Y Chang, Derrick C Wan, Michael T Longaker, Nature
- The Intestinal Epithelial Response to DamageOphir Klein, MD, Science China. Life Sciences
- Publisher Correction: Parasitic Helminths Induce Fetal-like Reversion in the Intestinal Stem Cell NicheOphir D Klein, Richard M Locksley, Nature
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Press Mentions
Prominent Pediatric Surgeon Selected for Key Roles at Cedars-Sinai Guerin Children’sOctober 25th, 2022- May Research Highlights: A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-SinaiMay 26th, 2022
- Mass Resignations at Scientific Journal over Ethically Fraught China Genetics PapersAugust 5th, 2021
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Grant Support
- The Role Of BMI1 In Regulation Of Dental Stem CellsNational Institute Of Dental &Craniofacial Research2011–2012
- The Role Of SPRY2 In Regulation Of Bone FormationNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2010–2012
- The Role Of Sprouty Genes In Development Of The Circumvallate PapillaNational Institute On Deafness And Other Communication Disorders2010–2011
- An Evolutionary-Developmental Approach To Stem Cells Using Teeth As A ModelOffice Of The Director, National Institutes Of Health2010
- The Role Of Micrornas In Tooth Regeneration Using The Mouse Incisor ModelNational Institute Of Dental &Craniofacial Research2009–2010
- Analysis Of The Role Of Sprouty Genes In Tooth DevelopmentNational Institute Of Dental &Craniofacial Research2007–2009
Professional Memberships
- Fellow
Hospital Affiliations
UCSF Medical CenterSan Francisco, California
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