Otto Orlean Yang MD

Professor, Medicine, UCLA School of Medicine

200 Medical Plaza# 365CLos Angeles, CA 90095
Phone+1 310-206-7663
Fax+1 310-206-1609

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Summary

Dr. Otto Yang, based in Los Angeles, CA, is an Infectious Disease specialist affiliated with UCLA Medical Center-Santa Monica and Ronald Reagan UCLA Medical Center. He completed his fellowship in Infectious Disease at Massachusetts General Hospital/Harvard Medical School, and his residency in Internal Medicine at NYU Grossman School of Medicine. Dr. Yang has significant experience in flow cytometry, virology, molecular biology, emerging infectious diseases, and cellular immunology. His recent publications include works in journals such as the Journal of Acquired Immune Deficiency Syndromes, Vaccine, and Scientific Reports. He is also involved in clinical trials, including studies on COVID-19 and HIV. Dr. Yang has been recognized with the CMS Meaningful Use Stage 1 Certification by Epic Systems Corporation.

Education & Training

Mass General Brigham/Massachusetts General Hospital/Brigham and Women's HospitalFellowship, Infectious Disease, 1993 - 1997
NYU Grossman School of MedicineResidency, Internal Medicine, 1990 - 1993
The Warren Alpert Medical School of Brown UniversityClass of 1990

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Certifications & Licensure

CA State Medical License 2000 - 2028
MA State Medical License 1993 - 2000

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Clinical Trials

Specimen Repository for HIV Immunopathogenesis Start of enrollment: 2017 Jul 31
COMPLETED
Evaluation of Activity and Safety of Oral Selinexor in Participants With Severe COVID-19 Infection Start of enrollment: 2020 Apr 17
COMPLETED
PHASE2
Study of Pentasa® for Reducing Residual Systemic Immune Activation in Treated HIV Infection Start of enrollment: 2017 May 01
COMPLETED
PHASE1, PHASE2

Publications & Presentations

PubMed

Atomically Precise Polyanionic Boron Cluster Agents with Broad-Spectrum Antiviral Activity.
Yueying Wang, Balamurugan Arumugam, Evan Doud, David DeLuca, Michael Rebelo
Precision Chemistry. 2026-05-25
Angut mucosal explant assay to compare HIV tissue susceptibility shows increased HIV susceptibility with methamphetamine exposure.
Julie Elliott, Nicholas E Webb, Grace D Cho, Ayub Ali, Peter A Anton
Biorxiv. 2026-02-05
3 citations
A New Approach to In Vivo Transformation of Killer T Cells.
Noe Rodriguez, Christian Hofmann, Otto O Yang, William M Gelbart
Journal of Molecular Biology. 2025-11-15

Journal Articles

Cross-Reactivity Against Multiple HIV-1 Epitopes Is Characteristic of HIV-1-Specific Cytotoxic T Lymphocyte Clones
Otto Yang, MD, mBio
Highly Attenuated Infection with a Vpr-Deleted Molecular Clone of HIV-1
Peter A Anton, Jennifer A Fulcher, Otto O Yang, Joel N Blankson, The Journal of Infectious Diseases

Press Mentions

Researchers Find a Way to Use Antibodies to Direct T Cells to Kill Cytomegalovirus-Infected CellsSeptember 12th, 2025
Antibodies Guide T Cells to Fight Cytomegalovirus | New ResearchSeptember 12th, 2025
Researchers Develop Antibody Therapy to Combat Cytomegalovirus InfectionSeptember 12th, 2025

Grant Support

Harnessing the Pathogenesis of CMV Against HIVUNIVERSITY OF CALIFORNIA LOS ANGELES2024–2029
Addressing Evolving Infectious ThreatsUNIVERSITY OF CALIFORNIA LOS ANGELES2023–2028
Addressing Evolving Infectious ThreatsUNIVERSITY OF CALIFORNIA LOS ANGELES2023–2028
Small Molecule Inhibitors Against HPV-Induced Orophageal CancersUNIVERSITY OF CALIFORNIA LOS ANGELES2025–2027
In vivo CAR-T-cell HIV therapy using in vitro reconstituted virus-like particlesUNIVERSITY OF CALIFORNIA LOS ANGELES2024–2026