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University of Minnesota Physicians424 Harvard Street SE First floor Suite M100Minneapolis, MN 55455
Phone+1 612-625-5411
Fax+1 612-625-6919
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Education & Training
University of MinnesotaFellowship, Hematology and Medical Oncology, 1994 - 1997
University of Iowa Health Care Medical CenterResidency, Internal Medicine, 1991 - 1994- University of Minnesota Medical SchoolClass of 1991
Certifications & Licensure
OK State Medical License 2008 - 2027
MN State Medical License 1995 - 2008
IA State Medical License 1991 - 1995
Clinical Trials
Publications & Presentations
PubMed
- Identification and evaluation of 41 risk loci for juvenile idiopathic arthritis informs precision medicine: mechanistic implications of DNA topology and an HLA-A*02:01...Hannah C Ainsworth, Ekaterina S Khvatkova, Marc Sudman, Miranda C Marion, Kaiyu Jiang
Medrxiv. 2026-09-17 - 2 citationsVariants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland.Mandi M Wiley, Marcin Radziszewski, Bhuwan Khatri, Michelle L Joachims, Kandice L Tessneer
Annals of the Rheumatic Diseases. 2025-09-01 - 1 citationsDefining three dimensional chromatin structures of pediatric and adolescent B cells using primary B cell and EBV-immortalized B cell reference genomes.Kaiyu Jiang, Yao Fu, Jennifer A Kelly, Patrick M Gaffney, Lucy C Holmes
BMC Medical Genomics. 2025-05-28
Journal Articles
- From Association to Mechanism in Complex Disease Genetics: The Role of the 3D GenomePatrick Gaffney, MD, BioMed Central
- Site-1 Protease Deficiency Causes Human Skeletal Dysplasia Due to Defective Inter-Organelle Protein TraffickingRodger P McEver, Sara Cathey, Patrick M Gaffney, The Journal of Clinical Investigation
- Genetic Variants at the 16p13 Locus Confer Risk for Eosinophilic EsophagitisRobert P Kimberly, Marc E Rothenberg, Patrick M Gaffney, Hugh A Sampson, J Pablo Abonia, Mirna Chehade, Philip E Putnam, Brian P Vickery, Glenn T Furuta, John B Harley, Nature
Press Mentions
Faster, More Precise Genetic Diagnoses Possible with OMRF TechnologySeptember 17th, 2026- Oklahoma Medical Research Foundation Scientist Receives $2.4 Million to Study Genetic MutationsJuly 24th, 2024
- OMRF Scientist Receives $2.4 Million to Study Genetic MutationsJuly 23rd, 2024
Grant Support
- Disease and Race Specific Single-cell Epigenetic Mechanisms in Human SLEOKLAHOMA MEDICAL RESEARCH FOUNDATION2021–2026
- Epigenome-Guided Causal Variant Discovery and MechanismsOKLAHOMA MEDICAL RESEARCH FOUNDATION2019–2025
- Molecular Mechanisms And Genetics Of AutoimmunityNational Institute Of General Medical Sciences2012
- Core D: Recruiting CoreNational Center For Research Resources2011
- Core A: Administrative CoreNational Center For Research Resources2011
Professional Memberships
- Member
- American Society of Human GeneticsMember
- Research Member
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