PatrickThomasGroganMD

PubMed

• 1 citations
  Case report: Radiographic complete response of radiation-induced glioblastoma to front-line radiotherapy: A report and molecular characterization of two unique cases.
  Patrick T Grogan, Jeffrey J Helgager, Dustin A Deming, Steven P Howard, Robert B Jenkins, H Ian Robins> ;Frontiers in Neurology. 2023 Jan 1
• 2 citations
  Entrectinib demonstrates prolonged efficacy in an adult case of radiation-refractoryfusion glioblastoma.
  Patrick T Grogan, Dustin A Deming, Jeffrey Helgager, Theresa Ruszkiewicz, Mustafa K Baskaya, Steven P Howard, H Ian Robins> ;Neuro-Oncology Advances. 2022 Apr 13
• 10 citations
  Novel C-terminal heat shock protein 90 inhibitors target breast cancer stem cells and block migration, self-renewal, and epithelial-mesenchymal transition.
  Chitra Subramanian, Patrick T. Grogan, Ton Wang, Joseph Bazzill, Ang Zuo, Peter T. White, Avinaash Kalidindi, Dawn Kuszynski, Grace M. Wang, Brian S. J. Blagg, Mark S....> ;Molecular Oncology. 2020 Sep 1
• 19 citations
  Therapy after cyclin-dependent kinase inhibition in metastatic hormone receptor-positive breast cancer: Resistance mechanisms and novel treatment strategies
  Marina N. Sharifi, Apoorva Anandan, Patrick T. Grogan, Ruth O'Regan> ;Cancer. 2020 Aug 1
• 9 citations
  Human Colon Organoids and Other Laboratory Strategies to Enhance Patient Treatment Selection.
  Katherine A. Johnson, Rebecca A. DeStefanis, Philip B. Emmerich, Patrick T. Grogan, Jeremy D. Kratz, Sarbjeet K. Makkar, Linda Clipson, Dustin A. Deming> ;Current Treatment Options in Oncology. 2020 Apr 23
• 12 citations
  Novel natural withanolides induce apoptosis and inhibit migration of neuroblastoma cells through down regulation of N-myc and suppression of Akt/mTOR/NF-κB activation.
  Chitra Subramanian, Patrick T. Grogan, Valerie P. Opipari, Barbara N. Timmermann, Mark S. Cohen> ;Oncotarget. 2018 Feb 7
• 53 citations
  Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory m...
  Patrick T. Grogan, Jann N. Sarkaria, Barbara N. Timmermann, Mark S. Cohen> ;Investigational New Drugs. 2014 Apr 10
• 59 citations
  Cytotoxicity of withaferin A in glioblastomas involves induction of an oxidative stress-mediated heat shock response while altering Akt/mTOR and MAPK signaling pathways
  Patrick T. Grogan, Kristina D. Sleder, Abbas Samadi, Huaping Zhang, Barbara N. Timmermann, Mark S. Cohen> ;Investigational New Drugs. 2013 Jun 1
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