PatrickBJohnstonMD

Hematology • Rochester, MN

Assistant Professor, Internal Medicine, Mayo Medical School

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Office
200 1st Street SW
Rochester, MN 55905
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Education & Training

Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Hematology and Medical Oncology, 1998 - 2001
Mayo Clinic College of Medicine and Science (Rochester)Residency, Internal Medicine, 1995 - 1998
University of Alabama School of MedicineClass of 1995

Certifications & Licensure

AZ State Medical License 1997 - Present
MN State Medical License 1996 - 2024
American Board of Internal Medicine Hematology

Clinical Trials

Trial of Oxaliplatin, Cytosine Arabinoside, Dexamethasone With Rituxan (ROAD) in Patients With Relapsed Non-Hodgkins Lymphoma Start of enrollment: 2005 Mar 01
Completed
Phase 2
Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma Start of enrollment: 2011 Jan 17
Completed
Phase 2
Everolimus, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Untreated Diffuse Large B-Cell Lymphoma Start of enrollment: 2012 Mar 01
Completed
Phase 1
Phase 1 Dose Finding Study of Belinostat for Treatment of Patients With Peripheral T-cell Lymphoma (PTCL) Start of enrollment: 2013 May 01
Completed
Phase 1
Everolimus and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma Start of enrollment: 2016 Feb 04
Terminated
Phase 1
Nivolumab & Brentuximab Vedotin Consolidation After Autologous SCT in Patients With High-Risk Classical Hodgkin Lymphoma Start of enrollment: 2017 Apr 03
Active, not recruiting
Phase 2
A Study of TAK-981 Given With Rituximab in Adults With Relapsed or Refractory CD20-Positive Non-Hodgkin Lymphoma Start of enrollment: 2019 Oct 15
Terminated
Phase 1, Phase 2
Roles: Principal Investigator
Evaluate the Safety and Clinical Activity of HH2853 Start of enrollment: 2020 Sep 08
Recruiting
Phase 1, Phase 2
Roles: Contact
DALY 2.0 USA/ MB-CART2019.1 for DLBCL Start of enrollment: 2021 May 25
Recruiting
Phase 2
Roles: Contact
Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study) Start of enrollment: 2021 Dec 29
Recruiting
Phase 2
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Plain language summary of the TRANSFORM study primary analysis results: lisocabtagene maraleucel as a second treatment regimen for large B-cell lymphoma following fail...
Jeremy S Abramson, Scott R Solomon, Jon Arnason, Patrick B Johnston, Bertram Glass, Veronika Bachanova, Sami Ibrahimi, Stephan Mielke, Pim Mutsaers, Francisco Hernande...> ;Future Oncology. 2024 Mar 28
Patterns of progression after immune checkpoint inhibitors for Hodgkin lymphoma: implications for radiation therapy.
Jessica F Burlile, Kelsey M Frechette, William G Breen, Steven R Hwang, Alexandra S Higgins, Adrienne N Nedved, William S Harmsen, Sydney D Pulsipher, Thomas E Witzig,...> ;Blood Advances. 2024 Mar 12
Serial Evaluation of Preimmunization Antibody Titers in Lymphoma Patients Receiving Chimeric Antigen Receptor T Cell Therapy.
Radhika Bansal, Paschalis Vergidis, Pritish K Tosh, John Wilson, Matthew Hathcock, Arushi Khurana, N Nora Bennani, Jonas Paludo, Jose C Villasboas, Yucai Wang, Stephen...> ;Transplantation and Cellular Therapy. 2024 Apr 1
Pralatrexate injection combined with CHOP for treatment of PTCL: results from the Fol-CHOP dose-finding phase 1 trial.
Stefan K Barta, Iyer, S., Johnston, P.> ;Blood Advances. 2024 Jan 23
Autologous stem cell transplant in fit patients with refractory or early relapsed diffuse large B-cell lymphoma that responded to salvage chemotherapy.
Tun, A., Bisneto, J., Wang, Y., Maliske, S., Micallef, I., Inwards, D., Habermann, T., Porrata, L., Paludo, J., Rosenthal, A., Kharfan-Dabaja, M., Ansell, S., Nowakows...> ;Haematologica. 2024 Jan 18
Day 100 Natural Killer Cell/CD14+HLA-DRratio and survival in lymphoma post-autologous peripheral blood hematopoietic stem cell transplantation.
Luis F Porrata, Stephen M Ansell, Ivana N Micallef, Patrick B Johnston, Jose C Villasboas, Jonas Paludo, Urshila Durani, Svetomir N Markovic> ;Clinical Transplantation. 2024 Jan 1
Real-world associations of cytokine release syndrome and neurotoxicity with efficacy in patients receiving anti-CD-19 chimeric antigen receptor T-cell therapy for larg...
Karan L Chohan, Radhika Bansal, Matthew A Hathcock, Jonas Paludo, Nora N Bennani, Patrick B Johnston, Arushi Khurana, Urshila Durani, Yucai Wang, Michael W Ruff, Jose ...> ;Leukemia & Lymphoma. 2024 Mar 1
2 citations
Metabolic PET/CT analysis of aggressive Non-Hodgkin lymphoma prior to Axicabtagene Ciloleucel CAR-T infusion: predictors of progressive disease, survival, and toxicity.
William G Breen, Jason R Young, Matthew A Hathcock, Roman O Kowalchuk, Matthew P Thorpe, Radhika Bansal, Arushi Khurana, N Nora Bennani, Jonas Paludo, Jose Villasboas ...> ;Blood Cancer Journal. 2023 Aug 18
1 citations
Consolidative radiotherapy for residual fluorodeoxyglucose activity on day +30 post CAR T-cell therapy in non-Hodgkin lymphoma.
Omran Saifi, William G Breen, Scott C Lester, William G Rule, Bradley J Stish, Allison Rosenthal, Javier Munoz, Yi Lin, Radhika Bansal, Matthew A Hathcock, Patrick B J...> ;Haematologica. 2023 Nov 1
Central nervous system involvement (Bing-Neel Syndrome) in patients with Waldenström macroglobulinemia.
Saurabh Zanwar, Jithma P Abeykoon, Stephen M Ansell, Morie A Gertz, Michelle Mauermann, Thomas E Witzig, Patrick Johnston, Robert A Kyle, Rebecca L King, Thomas M Habe...> ;Leukemia & Lymphoma. 2023 Jun 10
CAR-T Therapy in Lymphoma Patients With Coexisting Cardiomyopathy or Cardiac Lymphomatous Involvement.
Choon Ta Ng, Hilda M Gonzalez Bonilla, Ian Chang, M Tun Aung, Naveen L Pereira, Jose C Villasboas Bisneto, Patrick B Johnston, Hector R Villarraga, Martin G Rodriguez-...> ;JACC. Case Reports. 2023 Jun 7
2 citations
Response to COVID-19 Vaccination Post-CAR T Therapy in Patients With Non-Hodgkin Lymphoma and Multiple Myeloma.
Wiedmeier-Nutor, J., Iqbal, M., Rosenthal, A., Bezerra, E., Garcia-Robledo, J., Bansal, R., Johnston, P., Hathcock, M., Larsen, J., Bergsagel, P., Wang, Y., Reeder, C....> ;Clinical Lymphoma, Myeloma & Leukemia. 2023 Jun 1
4 citations
Barriers to enrollment in clinical trials of patients with aggressive B-cell NHL that progressed after CAR T-cell therapy.
Bezerra, E., Iqbal, M., Munoz, J., Khurana, A., Wang, Y., Maurer, M., Bansal, R., Hathcock, M., Bennani, N., Murthy, H., Rosenthal, A., Paludo, J., Villasboas, J., Joh...> ;Blood Advances. 2023 Apr 25
1 citations
Outcomes of Patients With Classic Hodgkin Lymphoma Who Relapsed After Autologous Stem Cell Transplant.
Yucai Wang, Aasiya Matin, David J Inwards, Thomas M Habermann, Ivana Micallef, Patrick B Johnston, Luis Porrata, Jonas Paludo, Jose Villasboas Bisneto, Allison Rosenth...> ;Hemasphere. 2023 Apr 1
6 citations
Procalcitonin as a biomarker for predicting bacterial infection in chimeric antigen receptor T-cell therapy recipients.
Marissa Z Powell, Kristin C Mara, Radhika Bansal, Matthew A Hathcock, Arushi Khurana, N Nora Bennani, Yucai Wang, Jonas Paludo, Jose Villasboas Bisneto, Stephen M Anse...> ;Cancer Medicine. 2023 Apr 1
2 citations
Pre-lymphodepletion & infusion endothelial activation and stress index as predictors of clinical outcomes in CAR-T therapy for B-cell lymphoma.
Aldo A Acosta-Medina, Isla McKerrow Johnson, Radhika Bansal, Matthew Hathcock, Saad J Kenderian, Urshila Durani, Arushi Khurana, Yucai Wang, Jonas Paludo, Jose C Villa...> ;Blood Cancer Journal. 2023 Jan 5
End-of-treatment PET in early-stage Hodgkin lymphoma: valuable in addition to interim PET.
Karan L Chohan, Jason R Young, Scott Lester, Muhamad Alhaj Moustafa, Allison Rosenthal, Han W Tun, Bradford S Hoppe, Patrick B Johnston, Ivana N Micallef, Thomas M Hab...> ;Haematologica. 2023 Jun 1
60 citations
Lisocabtagene maraleucel as second-line therapy for large B-cell lymphoma: primary analysis of the phase 3 TRANSFORM study.
Jeremy S Abramson, Scott R Solomon, Jon Arnason, Patrick B Johnston, Bertram Glass, Veronika Bachanova, Sami Ibrahimi, Stephan Mielke, Pim Mutsaers, Francisco Hernande...> ;Blood. 2023 Apr 6
6 citations
Don't Put the CART Before the Horse: The Role of Radiation Therapy in Peri-CAR T-cell Therapy for Aggressive B-cell Non-Hodgkin Lymphoma.
Omran Saifi, William G Breen, Scott C Lester, William G Rule, Bradley J Stish, Allison Rosenthal, Javier Munoz, Yi Lin, Radhika Bansal, Matthew A Hathcock, N Nora Benn...> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Aug 1
1 citations
Outcomes of Older Adults with Non-Hodgkin Lymphoma Undergoing Autologous Stem Cell Transplantation: A Mayo Clinic Cohort Analysis.
Kitsada Wudhikarn, Bradley M Johnson, David J Inwards, Luis F Porrata, Ivana N Micallef, Stephen M Ansell, Willam J Hogan, Jonas Paludo, Jose C Villasboas, Patrick B J...> ;Transplantation and Cellular Therapy. 2023 Mar 1
5 citations
Central nervous system involvement by mantle cell lymphoma.
Nicole McLaughlin, Yucai Wang, Thomas Witzig, Jose Villasboas, Thomas Habermann, David Inwards, Nora Bennani, Gita Thanarajasingam, Grzegorz Nowakowski, Luis Porrata, ...> ;Leukemia & Lymphoma. 2023 Feb 1
13 citations
Brentuximab vedotin plus nivolumab after autologous haematopoietic stem-cell transplantation for adult patients with high-risk classic Hodgkin lymphoma: a multicentre,...
Alex F Herrera, Lu Chen, Yago Nieto, Leona Holmberg, Patrick Johnston, Matthew Mei, Leslie Popplewell, Saro Armenian, Thai Cao, Leonardo Farol, Firoozeh Sahebi, Ricard...> ;The Lancet. Haematology. 2023 Jan 1
1 citations
High-Dose Methotrexate in Patients With Lymphoma: Predictors of a Complicated Course.
Darragh F O'Donoghue, Huong L Truong, Heidi D Finnes, Jennifer S McDonald, Heather P May, Stephen M Ansell, N Nora Bennani, Thomas M Habermann, David J Inwards, Patric...> ;JCO Oncology Practice. 2022 Dec 1
5 citations
Health-related quality of life with lisocabtagene maraleucel vs standard of care in relapsed or refractory LBCL.
Jeremy S Abramson, Patrick B Johnston, Manali Kamdar, Sami Ibrahimi, Koji Izutsu, Jon Arnason, Bertram Glass, Pim Mutsaers, Matthew Lunning, Julia Braverman, Fei Fei L...> ;Blood Advances. 2022 Dec 13
3 citations
Clinical characteristics, prognostic indicators, and survival outcomes in intravascular lymphoma: Mayo Clinic experience (2003-2018).
Karan Seegobin, Zhuo Li, Muhamad Alhaj Moustafa, Umair Majeed, Jing Wang, Liuyan Jiang, Justin Kuhlman, David Menke, Ke Li, Mohamed A Kharfan-Dabaja, Ernesto Ayala, Ma...> ;American Journal of Hematology. 2022 Sep 1
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Journal Articles

Primary Systemic Amyloidosis in Patients with Waldenström Macroglobulinemia
Angela Dispenzieri, Eli Muchtar, Ronald Go, Saurabh Zanwar, Surbhi Sidana, Francis Buadi, Stephen M Ansell, Prashant Kapoor, David Dingli, Thomas Habermann, Shaji Kuma..., Nature
Phase 2 Study of Everolimus for Relapsed or Refractory Classical Hodgkin Lymphoma
Patrick B. Johnston, Radhakrishnan Ramchandren, Lauren C. Pinter-Brown, BioMed Central
Phase I Study of Pomalidomide and Dexamethasone for relapsed/refractory Primary CNS or Vitreo-Retinal Lymphoma
Lisa M DeAngelis, Han W Tun, David Schiff, Kurt A Jaeckle, Christian Grommes, Patrick B Johnston, Craig B Reeder, Thomas E Witzig, Blood

Abstracts/Posters

Clinical Features and Treatment for Neurolymphomatosis in the Rituximab Era: Single Institution Experience
Patrick Johnston, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Peak Lymphocyte Count after CAR T Infusion Is a Clinically Accessible Test That Correlates with Clinical Response in Axicabtagene Ciloleucel Therapy for Lymphoma
Patrick Johnston, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Event-Free Survival at 24 Months Following Autologous Stem Cell Transplant in Diffuse Large B-Cell Lymphoma
Patrick Johnston, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

Hematologic Malignancies: New Therapies and the Evolving Role of Transplant
Mayo School of Continuous Professional Development, Chicago, Illinois - 10/11/2013
Hematologic Malignancies: New Therapies and the Evolving Role of Transplant
Mayo School of Continuous Professional Development, Chicago, Illinois - 10/11/2013