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Office
1301 Morris Park Ave
Bronx, NY 10461- Is this information wrong?
Education & Training
- Harvard Medical SchoolPost-Doctoral Fellowship, Harvard-Longwood Vascular Research Fellowship, 1994 - 1998
- Tufts Medical CenterFellowship, Hematology and Medical Oncology, 1991 - 1994
- Montreal General HospitalInternal Medicine, 1988 - 1991
- Laval UnivClass of 1988
Certifications & Licensure
- NY State Medical License 2007 - 2023
Awards, Honors, & Recognition
- Elected Member The American Association of Physician, 2008
- Elected Member The American Society for Clinical Investigation, 2004
Publications & Presentations
PubMed
- 6 citationsDietary iron restriction protects against vaso-occlusion and organ damage in murine sickle cell disease.Jacob S Kazmi, Sungkyun Lee, Dachuan Zhang, Xin Gao, Maria Maryanovich, Lidiane Torres, Divij Verma, Libusha Kelly, Yelena Z Ginzburg, Paul S Frenette, Deepa Manwani, ...> ;Blood. 2023 Jan 12
- 35 citationsThe microbiota regulates hematopoietic stem cell fate decisions by controlling iron availability in bone marrow.Dachuan Zhang, Xin Gao, Daniel K Borger, Qiaozhi Wei, Eva Yang, Chunliang Xu, Sandra Pinho, Paul S Frenette, Huihui Li> ;Cell Stem Cell. 2022 Feb 3
- 11 citationsOlinciguat, a stimulator of soluble guanylyl cyclase, attenuates inflammation, vaso-occlusion and nephropathy in mouse models of sickle cell disease.Boris Tchernychev, Huihui Li, Sung Kyun Lee, Xin Gao, Raghunath Ramanarasimhaiah, Guang Liu, Katherine C. Hall, Sylvie G. Bernier, Juli E. Jones, Susanne Feil, Robert ...> ;British Journal of Pharmacology. 2021 Sep 1
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Abstracts/Posters
- Macrophage Transfer to HSCs Assigns Residence in Bone MarrowPaul S. Frenette, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
- The Gut Microbiome Regulates Psychological Stress-Induced Inflammation in Sickle Cell DiseasePaul S. Frenette, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
- VCAM1 Confers Innate Immune Tolerance on Hematopoietic and Leukemic Stem CellsPaul S. Frenette, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Press Mentions
- Nociceptive Neurons Shown to Boost HematopoiesisDecember 28th, 2020
- Cygnal Therapeutics Announces Scientific Advisory BoardJanuary 31st, 2020
- Conditions Found That Promote Proliferation of Blood-Forming Cells in Fetal LiverJanuary 11th, 2016
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Grant Support
- Mechanisms Mediating Hematopoietic Stem And Progenitor Cell TraffickingNational Institute Of Diabetes And Digestive And Kidney Diseases2010–2011
- Role Of Mesenchymal Stem Cells In The Blood Stem Cell NicheNational Heart, Lung, And Blood Institute2010–2011
- Mechanisms Mediating Circadian Oscillations Of Leukocyte MigrationNational Heart, Lung, And Blood Institute2010–2011
- Adhesion Mechanisms Mediating Sickle Cell Vasoocclusion In VivoNational Heart, Lung, And Blood Institute2010–2011
- Inhibition Of Platelet-Leukocyte Interactions To Treat TraliNational Heart, Lung, And Blood Institute2010
- Adhesion Mechanisms Mediating Sickle Cell Vasoocclusion In VivoNational Heart, Lung, And Blood Institute2010
- Role Of Mesenchymal Stem Cells In The Blood Stem Cell NicheNational Heart, Lung, And Blood Institute2009
- Mechanisms Mediating Circadian Oscillations Of Leukocyte MigrationNational Heart, Lung, And Blood Institute2009
- Inhibition Of Platelet-Leukocyte Interactions To Treat TraliNational Heart, Lung, And Blood Institute2009
- Adhesion Mechanisms Mediating Sickle Cell Vasoocclusion In VivoNational Heart, Lung, And Blood Institute2008–2009
- Mechanisms Mediating Stem/Progenitor Cell Mobilization From Bone MarrowNational Institute Of Diabetes And Digestive And Kidney Diseases2006–2009
- Clinical Trial: Treatment Of Sickle Cell Vaso-Occlusive Crisis With High Dose IVNational Center For Research Resources2008
- Assay Development For High Throughput Screening Of Selectin Ligand AntagonistsNational Institute Of Allergy And Infectious Diseases2006–2008
- Treatment Of Sickle Cell Vaso-Occlusive Crisis With High Dose IVIGNational Center For Research Resources2007
- HTS Assay Development For Inhibitors Of Sickle CellNational Human Genome Research Institute2005–2006
- In Vivo Sickle Cell Vasoocclusion: Adhesion MechanismsNational Heart, Lung, And Blood Institute2001–2004
- Adhesion Pathways Of Blood/Endothelial ProgenitorsNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2004
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