PaulJohnGalardyMD

PubMed

• MRD at the End of Induction and EFS in T-cell Lymphoblastic Lymphoma: Children's Oncology Group Trial AALL1231.
  Robert J Hayashi, Michelle L Hermiston, Brent L Wood, David Trent Teachey, Meenakshi Devidas, Zhiguo Chen, Robert D Annett, Barbara L Asselin, Keith August, Steve Cho,...> ;Blood. 2024 Mar 8
• Neonatal hemophagocytic lymphohistiocytosis: A meta-analysis of 205 cases.
  Lincoln A Kranz, Wyatt S Hahn, Whitney S Thompson, Roland Hentz, Nathan L Kobrinsky, Paul Galardy, Jacob R Greenmyer> ;Pediatric Blood & Cancer. 2024 Apr 1
• Attempted desensitization to calaspargase pegol: a familiar approach to a new problem.
  Alexis K Kuhn, Catherine Martin, Paul Galardy, Kristen McCullough, Jacob Greenmyer, Madeleine O'Keefe, Ashley Walter, Christineil Thompson, Asmaa Ferdjallah, Jessica K...> ;Leukemia & Lymphoma. 2024 Mar 1
• An Effective Combination Therapy for the Treatment of Pediatric Monomorphic Post-transplant Lymphoproliferative Disorder With Plasmacytic Differentiation.
  Mihai Dumbrava, Paul Galardy, Andrew L Feldman, Alexis Kuhn, Shakila Khan, Asmaa Ferdjallah, Mira A Kohorst> ;Journal of Pediatric Hematology/oncology. 2023 Jul 1
• 1 citations
  Symptomatic hyperammonemia secondary to recombinant Erwinia asparaginase.
  Catherine E Martin, Mira A Kohorst, Asmaa Ferdjallah, Jessica L Kalmes, Heather M Johnson, Paul J Galardy, Shakila P Khan, Alexis K Kuhn> ;Pediatric Blood & Cancer. 2023 May 1
• 4 citations
  Pediatric Aggressive Mature B-Cell Lymphomas, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology.
  Matthew Barth, Ana C Xavier, Saro Armenian, Anthony N Audino, Lindsay Blazin, David Bloom, Jong Chung, Kimberly Davies, Hilda Ding, James B Ford, Paul J Galardy, Rabi ...> ;Journal of the National Comprehensive Cancer Network. 2022 Nov 1
• 2 citations
  Neonatal familial hemophagocytic lymphohistiocytosis diagnosed with ultrarapid whole-genome sequencing.
  Jacob R Greenmyer, Whitney S Thompson, Stephanie Mavis, Sara Hassan, Jody Weckwerth, Charlotte Hobbs, Kiely James, Shareef Nahas, Paul Galardy, Christopher Collura> ;Pediatric Blood & Cancer. 2023 Jan 1
• 40 citations
  Children's Oncology Group Trial AALL1231: A Phase III Clinical Trial Testing Bortezomib in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia and Lymphoma.
  David T Teachey, Meenakshi Devidas, Brent L Wood, Zhiguo Chen, Robert J Hayashi, Michelle L Hermiston, Robert D Annett, J Hunter Archer, Barbara L Asselin, Keith J Aug...> ;Journal of Clinical Oncology. 2022 Jul 1
• 3 citations
  Chromosome instability in neuroblastoma: A pathway to aggressive disease.
  Lucia Paolini, Sajjad Hussain, Paul J Galardy> ;Frontiers in Oncology. 2022 Jan 1
• 5 citations
  USP44 Stabilizes DDB2 to Facilitate Nucleotide Excision Repair and Prevent Tumors.
  Ying Zhang, Imke K Mandemaker, Syota Matsumoto, Oded Foreman, Christopher P. Holland, Whitney R. Lloyd, Kaoru Sugasawa, Wim Vermeulen, Jurgen A. Marteijn, Paul J. Galardy> ;Frontiers in Cell and Developmental Biology. 2021 Apr 16
• 5 citations
  Optimization and Anti-Cancer Properties of Fluoromethylketones as Covalent Inhibitors for Ubiquitin C-Terminal Hydrolase L1
  Aaron D Krabill, Hao Chen, Sajjad Hussain, Chad S. Hewitt, Ryan D Imhoff, Christine S Muli, Chittaranjan Das, Paul J. Galardy, Michael K. Wendt, Daniel P. Flaherty> ;Molecules. 2021 Feb 25
• 2 citations
  Evolution of pediatric gastrointestinal ulcer disease: Is acute surgical intervention relevant?
  Alyssa D. Brown, Michael D. Traynor, D. Dean Potter, Michael B. Ishitani, Christopher R. Moir, Paul J. Galardy, Denise B. Klinkner> ;Journal of Pediatric Surgery. 2021 Feb 16
• 10 citations
  USP24 Is a Cancer-Associated Ubiquitin Hydrolase, Novel Tumor Suppressor, and Chromosome Instability Gene Deleted in Neuroblastoma
  Tibor Bedekovics, Sajjad Hussain, Ying Zhang, Asma Ali, Young J Jeon, Paul J. Galardy> ;Cancer Research. 2021 Mar 1
• Corrigendum: Ubiquitin C-Terminal Hydrolase L1: Biochemical and Cellular Characterization of a Covalent Cyanopyrrolidine-Based Inhibitor.
  Aaron D Krabill, Hao Chen, Sajjad Hussain, Chao Feng, Ammara Abdullah, Chad S Hewitt, Chittaranjan Das, Uma K Aryal, Carol Beth Post, Michael K Wendt, Paul J Galardy, ...> ;Chembiochem. 2020 Sep 14
• 35 citations
  The deubiquitinase USP44 promotes Treg function during inflammation by preventing FOXP3 degradation
  Jing Yang, Ping Wei, Joseph Barbi, Qianru Huang, Evan Yang, Yakun Bai, Jia Nie, Yanhang Gao, Jinhui Tao, Ying Lu, Chichu Xie, Xiaoxia Hou, Jiazi Ren, Xingmei Wu, Jian ...> ;EMBO Reports. 2020 Sep 3
• 59 citations
  Pediatric Aggressive Mature B-Cell Lymphomas, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.
  Kimberly Davies, Matthew J. Barth, Saro H. Armenian, Anthony N. Audino, Phillip Barnette, Branko Cuglievan, Hilda Ding, James B. Ford, Paul J. Galardy, Rebecca Gardner...> ;Journal of the National Comprehensive Cancer Network. 2020 Aug 1
• 5 citations
  Walking the tightrope: UCH-L1 as an mTOR inhibitor and B-cell oncogene.
  Tibor Bedekovics, Sajjad Hussain, Paul J. Galardy> ;Oncotarget. 2019 Aug 27
• 13 citations
  Ubiquitin C-Terminal Hydrolase L1: Biochemical and Cellular Characterization of a Covalent Cyanopyrrolidine-Based Inhibitor.
  Aaron D Krabill, Hao Chen, Sajjad Hussain, Chao Feng, Ammara Abdullah, Chittaranjan Das, Uma K Aryal, Carol Beth Post, Michael K Wendt, Paul J Galardy, Daniel P Flaherty> ;Chembiochem. 2020 Mar 2
• 1 citations
  Lymphoma diagnostics: getting more from less.
  Paul J. Galardy, Tibor Bedekovics, Elizabeth Macintyre, Rodney R. Miles> ;British Journal of Haematology. 2019 Jun 1
• 19 citations
  Excellent outcomes in children and adolescents with CNS+ Burkitt lymphoma or other mature B-NHL using only intrathecal and systemic chemoimmunotherapy: results from FA...
  J. Kimble Frazer, Kevin J. Li, Paul J. Galardy, Sherrie L. Perkins, Anne Auperin, James R. Anderson, Ross Pinkerton, Allen Buxton, Thomas G. Gross, Jean Michon, Guy Le...> ;British Journal of Haematology. 2019 Apr 1
• A cysteine near the C-terminus of UCH-L1 is dispensable for catalytic activity but is required to promote AKT phosphorylation, eIF4F assembly, and malignant B-cell sur...
  Sajjad Hussain, Tibor Bedekovics, Asma Ali, Omar Zaid, Danielle G May, Kyle J Roux, Paul J Galardy> ;Cell Death Discovery. 2019 Jan 1
• 14 citations
  Ibrutinib significantly inhibited Bruton's tyrosine kinase (BTK) phosphorylation,in-vitro proliferation and enhanced overall survival in a preclinical Burkitt lymphoma...
  Yaya Chu, Sanghoon Lee, Tishi Shah, Changhong Yin, Matthew J. Barth, Rodney R. Miles, Janet Ayello, Erin Morris, Lauren Harrison, Carmella van de Ven, Paul J. Galardy,...> ;Oncoimmunology. 2019 Jan 1
• 27 citations
  UCH-L1 bypasses mTOR to promote protein biosynthesis and is required for MYC-driven lymphomagenesis in mice
  Sajjad Hussain, Tibor Bedekovics, Qiuying Liu, Wenqian Hu, Haeseung Jeon, Sarah H. Johnson, George Vasmatzis, Danielle G. May, Kyle J. Roux, Paul J. Galardy> ;Blood. 2018 Dec 13
• 1 citations
  Suspected thrombotic microangiopathy in a child with Epstein–Barr virus-induced hemophagocytic lymphohistiocytosis
  Margaret C Cupit-Link, Mira A. Kohorst, Cheryl L. Tran, Jack J. Bleesing, Paul J. Galardy, Thomas G. Boyce> ;Pediatric Blood & Cancer. 2018 Jun 1
• Keeping an Open Mind: Cognitive Bias in the Evaluation of an Infant with Posterior-Lateral Rib Fractures.
  Katie Johnson, Donald Chris Derauf, Raymond C. Stetson, Paul J. Galardy, Jason H. Homme> ;Case Reports in Pediatrics. 2017 Oct 26
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Journal Articles

• UCH-L1 Bypasses mTOR to Promote Protein Biosynthesis and Is Required for MYC Driven Lymphomagenesis in Mice  
  Paul Galardy, MD, Blood