Paul H Hayashi MD

Hepatology & Liver Transplantation

Assistant Professor, Medicine, University of North Carolina-Chapel Hill School of Medicine

101 Manning DrChapel Hill, NC 27514
Phone+1 919-966-4996
Fax+1 919-843-5515

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Education & Training

Saint Louis UniversityM.P.H., 2003 - 2006
University of California Davis HealthFellowship, Gastroenterology, 1990 - 1993
University of California Davis HealthResidency, Internal Medicine, 1987 - 1990
University of California San Diego School of MedicineClass of 1987
University of California, Los AngelesB.A., Microbiology, Summa Cum Laude, 1979 - 1983

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Certifications & Licensure

CA State Medical License 1988 - Present
NC State Medical License 2006 - 2020
CO State Medical License 2002 - 2005
American Board of Internal Medicine Transplant Hepatology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification WebCIS, UNC Health Care, 2012, 2014-2017
CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014-2017
CMS Meaningful Use Stage 2 Certification EpicCare Inpatient 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014-2017

Clinical Trials

Uncertainty Management Intervention
COMPLETED
NA

Publications & Presentations

PubMed

R Value-Based Criteria Outperform Alkaline Phosphatase Less than Twice Normal in Identifying Hy's Law Cases in Clinical Trials.
Jasmine Amirzadegan, Edwige Chiogo Vouffo, Ling Lan, Eileen Navarro Almario, Mark I Avigan
Drug Safety. 2026-02-01
2 citations
Emerging Tools to Support DILI Assessment in Clinical Trials with Abnormal Baseline Serum Liver Tests or Pre-existing Liver Diseases.
Jasmine Amirzadegan, Bereket Tesfaldet, Y Veronica Pei, Eileen Navarro Almario, Mark I Avigan
Drug Safety. 2025-05-01
7 citations
The Clinical Spectrum and Diagnosis of Oxaliplatin Liver Injury in the Era of Nonalcoholic Fatty Liver Disease.
Hannah P. Kim, Victor Navarro, Steven Zacks, Joseph A. Odin, David E. Kleiner
Clinical Gastroenterology and Hepatology. 2021-10-01

Journal Articles

DILIN Network Idiosyncratic Drug-Induced Liver Injury Is Associated With Substantial Morbidity and Mortality Within 6 Months From Onset
Fontana RJ, Hayashi PH, Gu J, Reddy KR, Barnhart H, Watkins PB, Serrano J, Lee WM, Chalasani N, Stolz A, Davern T, Talwakar JA, Gastroenterology, 1/27/2014
Reliability of causality assessment for drug, herbal and dietary supplement hepatotoxicity in the Drug Induced Liver Injury Network (DILIN)
Hayashi PH, Barnhart HX, Fontana RJ, Chalasani N, Davern TJ, Talwalkar JA, Reddy KR, Stolz AA, Hoofnagle JH, Rockey DC, Liver International, 1/24/2014
ACG Clinical Guideline: The Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury
Chalasani NP, Hayashi PH, Bonkovsky HL, Navarro VJ, Lee WM, Fontana RJ, Am J Gastroenterol, 1/17/2014

Books/Book Chapters

Transplantation of the Liver
Chapter: Adult Living Donor and Recipient Evaluation and Selection.
Trotter JF, Hayashi PH, Kam IEditors: Busuttil RW, Klintmalm GB.W.B. Saunders, Philadelphia, PAEdition 2nd,2005
Pocket ICU Management
Chapter: Hepatopulmonary Syndrome.
Hayashi PHEditors: Farmer JC, Wall MH.PocketMedicine.com, Inc., New York, NY2003
Pocket ICU Management
Chapter: Ascites and Hepatorenal Syndrome.
Hayashi PHEditors: Farmer JC, Wall MH.PocketMedicine.com, Inc., New York, NY2003

Abstracts/Posters

Decreased Inpatient Mortality Amongst U.S. Cirrhotic Patients from 2002-2010: Evidence of Improving Inpatient Cirrhosis Care. Poster Presentation
Schmidt M, Barritt AS, Orman ES, Hayashi PH, 1/1/2013
Poor Adherence to Isoniazid (INH) Monitoring Guidelines is Common in Cases of INH Hepatotoxicity and is Associated with More Severe Liver Injury: Experience of The Dr...
Hayashi PH, Davern TJ, Fontana RJ, Chalasani NP, Stolz AA, Talwalker JA, Navarro VJ, Lee WM, Kleiner DE, Gu J, Hoofnagle JH for the Drug Induced Liver Injury Network (..., 1/1/2013
Use of Hemodialysis for Cirrhotic Patients with Acute Kidney Injury in the US: Trends from 2002-2010. Poster Presentation
Schmidt M, Barritt AS, Hayashi PH, Orman ES, 1/1/2013

Lectures

Update in Cirrhosis Care and Transplantation
1/14/2013
Update in Hepatology
New Hanover Regional Medical Center, Wilmington, NC - 1/10/2013
Review and Update in the Treatment of Hepatocellular Carcinoma: Triumphs and Pitfalls of Technology.
1/2/2013