PaulineFunchainMD

PubMed

• Clinical and Immunologic Features of Germline Pathogenic Variant-Positive Patients with Melanoma.
  Alan Shen, Michelle Arbesman, Roshan Lodha, Patricia Rayman, Brandon Bungo, Ying Ni, Timothy Chan, Brian Gastman, Jennifer Ko, C Marcela Diaz-Montero, Joshua Arbesman,...> ;Clinical Cancer Research. 2024 Feb 1
• 1 citations
  MC1R signaling through the cAMP-CREB/ATF-1 and ERK-NFκB pathways accelerates G1/S transition promoting breast cancer progression.
  Vipin Shankar Chelakkot, Kiara Thomas, Todd Romigh, Andrew Fong, Lin Li, Shira Ronen, Shuyang Chen, Pauline Funchain, Ying Ni, Joshua Arbesman> ;NPJ Precision Oncology. 2023 Sep 7
• 11 citations
  Systemic Therapy for Melanoma: ASCO Guideline Update.
  Rahul Seth, Sanjiv S Agarwala, Hans Messersmith, Krishna C Alluri, Paolo A Ascierto, Michael B Atkins, Kathryn Bollin, Matias Chacon, Nancy Davis, Mark B Faries, Pauli...> ;Journal of Clinical Oncology. 2023 Oct 20
• 7 citations
  Safety and Activity of Immune Checkpoint Inhibitors in People Living With HIV and Cancer: A Real-World Report From the Cancer Therapy Using Checkpoint Inhibitors in Pe...
  Dobbs, R. W., Talal El Zarif, Amin H Nassar, Elio Adib, Bailey G Fitzgerald, Jiaming Huang, Tarek H Mouhieddine, Paul G Rubinstein, Taylor Nonato, Rana R McKay, Mingji...> ;Journal of Clinical Oncology. 2023 Jul 20
• 1 citations
  Predictors for the development of neurological immune-related adverse events of immune checkpoint inhibitors and impact on mortality.
  Chen Yan, Merry Huang, Carol Swetlik, Karlo Toljan, Ahmad Z Mahadeen, James Bena, Amy Kunchok, Pauline Funchain, Marisa McGinley> ;European Journal of Neurology. 2023 Oct 1
• Melanoma body site distribution: Germline genetics may have a lesser role.
  Lorvens Decosma, Ying Ni, Pauline Funchain, Joshua Arbesman> ;JAAD International. 2023 Jun 1
• Reincarnating autoimmunity: Immune-related adverse events as new diseases.
  Pauline Funchain> ;Cleveland Clinic Journal of Medicine. 2023 May 1
• Characteristics of Immune Checkpoint Inhibitor-Associated Gastritis: Report from a Major Tertiary Care Center.
  Natalie Farha, Muhammad Salman Faisal, Daniela S Allende, Joseph Sleiman, Pauline Funchain, Jessica R Philpott, Farha, N., Shah, R.> ;The Oncologist. 2023 Aug 3
• 101 citations
  Combination Dabrafenib and Trametinib Versus Combination Nivolumab and Ipilimumab for Patients With Advanced-Mutant Melanoma: The DREAMseq Trial-ECOG-ACRIN EA6134.
  Atkins, M., Lee, S., Chmielowski, B., Tarhini, A., Cohen, G., Truong, T., Moon, H., Davar, D., O'Rourke, M., Stephenson, J., Curti, B., Urba, W., Brell, J., Funchain, ...> ;Journal of Clinical Oncology. 2023 Jan 10
• 3 citations
  InterMEL: An international biorepository and clinical database to uncover predictors of survival in early-stage melanoma.
  Irene Orlow, Keimya D Sadeghi, Sharon N Edmiston, Jessica M Kenney, Cecilia Lezcano, James S Wilmott, Anne E Cust, Richard A Scolyer, Graham J Mann, Tim K Lee, Hazel B...> ;Plos One. 2023 Jan 1
• Role of C-Reactive Protein in Predicting the Severity and Response of Immune-Mediated Diarrhea and Colitis in Patients with Cancer.
  Cynthia Liu, Malek Shatila, Antony Mathew, Antonio Pizuorno Machado, Austin Thomas, Hao Chi Zhang, Anusha S Thomas, David Faleck, Pauline Funchain, Jessica Philpott, P...> ;Journal of Cancer. 2023 Jan 1
• 1 citations
  Effectiveness of Adjuvant Pembrolizumab vs High-Dose Interferon or Ipilimumab for Quality-of-Life Outcomes in Patients With Resected Melanoma: A Secondary Analysis of ...
  Joseph M Unger, Amy Darke, Megan Othus, Thach-Giao Truong, Nikhil Khushalani, Kari Kendra, Karl D Lewis, Bryan Faller, Pauline Funchain, Elizabeth I Buchbinder, Ahmad ...> ;JAMA Oncology. 2023 Feb 1
• 5 citations
  Immune checkpoint inhibitor induced myocarditis, myasthenia gravis, and myositis: A single-center case series.
  Joshua Longinow, Mohammad Zmaili, Warren Skoza, Nicholas Kondoleon, Robert Marquardt, Cassandra Calabrese, Pauline Funchain, Rohit Moudgil> ;Cancer Medicine. 2023 Feb 1
• 5 citations
  Thromboembolism in Patients with Metastatic Urothelial Cancer Treated with Immune Checkpoint Inhibitors.
  Iris Y Sheng, Shilpa Gupta, Chandana A Reddy, Dana Angelini, Pauline Funchain, Tamara A Sussman, Joseph Sleiman, Moshe C Ornstein, Keith McCrae, Alok A Khorana> ;Targeted Oncology. 2022 Sep 1
• 3 citations
  A phase II study of TAS-117 in patients with advanced solid tumors harboring germline-inactivating mutations.
  Jordi Rodón, Pauline Funchain, Theodore W Laetsch, Hendrik-Tobias Arkenau, Alice Hervieu, Christian F Singer, Yonina R Murciano-Goroff, Sant P Chawla, Kristin Anthony,...> ;Future Oncology. 2022 Sep 1
• 3 citations
  Outcomes of stage IV melanoma in the era of immunotherapy: a National Cancer Database (NCDB) analysis from 2014 to 2016.
  Tamara A Sussman, Rebecca Knackstedt, Wei Wei, Pauline Funchain, Brian R Gastman> ;Journal for Immunotherapy of Cancer. 2022 Aug 1
• 6 citations
  Landscape of mutations in early stage primary cutaneous melanoma: An InterMEL study.
  Li Luo, Ronglai Shen, Arshi Arora, Irene Orlow, Klaus J Busam, Cecilia Lezcano, Tim K Lee, Eva Hernando, Ivan Gorlov, Christopher Amos, Marc S Ernstoff, Venkatraman E ...> ;Pigment Cell & Melanoma Research. 2022 Nov 1
• 1 citations
  Characterizing melanoma in the setting of oculocutaneous albinism: an analysis of the literature.
  S Ravichandran, P Funchain, J Arbesman> ;Archives of Dermatological Research. 2023 Oct 1
• 4 citations
  Systemic Therapy for Melanoma: ASCO Guideline Rapid Recommendation Update.
  Rahul Seth, Hans Messersmith, Pauline Funchain> ;Journal of Clinical Oncology. 2022 Jul 20
• 2 citations
  Gastrointestinal Toxicities of Immune Checkpoint Inhibitors Are Associated With Enhanced Tumor Responsiveness and Improved Survival.
  Mohammad Alomari, Suleiman Al Ashi, Pravallika Chadalavada, Shrouq Khazaaleh, Fahrettin Covut, Laith Al Momani, Ahmed Elkafrawy, Vinay Padbidri, Pauline Funchain, Dona...> ;Gastroenterology Research. 2022 Apr 1
• 28 citations
  A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients.
  Chuan Li, Yee Peng Phoon, Keaton Karlinsey, Ye F Tian, Samjhana Thapaliya, Angkana Thongkum, Lili Qu, Alyssa Matz, Mark J. Cameron, Cheryl M. Cameron, Antoine Ménoret,...> ;The Journal of Experimental Medicine. 2022 Jan 3
• Circulating Tumor DNA Testing Supports Rapid Therapeutic Decision-Making in Metastatic Melanoma: A Case Report.
  Tapas Ranjan Behera, Jung Min Song, Jennifer Ko, Donald Eicher, Joshua Arbesman, Brian Gastman, Daniel H Farkas, Pauline Funchain> ;Frontiers in Oncology. 2022 Jan 1
• 17 citations
  Adjuvant pembrolizumab versus interferon alfa-2b or ipilimumab in resected high-risk melanoma.
  Kenneth F. Grossmann, Megan Othus, Sapna Pradyuman Patel, Ahmad A. Tarhini, Vernon K. Sondak, Michael V. Knopp, Teresa M. Petrella, Thach-Giao Truong, Nikhil I. Khusha...> ;Cancer Discovery. 2021 Nov 11
• 9 citations
  Thromboembolism in Patients with Metastatic Renal Cell Carcinoma Treated with Immunotherapy.
  Iris Yeong Fung Sheng, Shilpa Gupta, Chandana A. Reddy, Dana E. Angelini, Pauline Funchain, Tamara A. Sussman, Joseph Sleiman, Moshe Chaim Ornstein, Keith R. McCrae, A...> ;Targeted Oncology. 2021 Nov 6
• 454 citations
  Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: ASCO Guideline Update.
  Bryan J. Schneider, Jarushka Naidoo, Bianca Santomasso, Christina Lacchetti, Sherry Adkins, Milan J. Anadkat, Michael B. Atkins, Kelly J. Brassil, Jeffrey M. Caterino,...> ;Journal of Clinical Oncology. 2021 Nov 1
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Abstracts/Posters

• Biomarker Assessment of Venous Thromboembolism in Cancer Patients Receiving Checkpoint Blockade
  Pauline Funchain, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

• Multiplex germline testing in selected melanomas presenting to oncology clinic. 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/2/2018