PeterForsythMD

Neuro-Oncology

Physician

Overview of Dr. Forsyth

Dr. Peter Forsyth is an oncologist in Tampa, FL and is affiliated with H. Lee Moffitt Cancer Center and Research Institute. He received his medical degree from Michael G. DeGroote School of Medicine and has been in practice 30 years. He is one of 172 doctors at H. Lee Moffitt Cancer Center and Research Institute who specialize in Oncology. He has more than 100 publications and over 500 citings.

Office
12902 USF Magnolia Drive
Tampa, FL 33612
Book by Phone+1(813) 686-7006

Fax+1 813-449-8246
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Education & Training

Mayo Clinic College of Medicine and Science (Rochester)Residency, Neurology, 1988 - 1991
Michael G. DeGroote School of MedicineClass of 1987

Certifications & Licensure

FL State Medical License 2011 - 2025
CT State Medical License 1993 - 1994
American Board of Psychiatry and Neurology Neurology

Clinical Trials

RO4929097 in Treating Patients With Recurrent Invasive Gliomas Start of enrollment: 2011 Jul 01
Terminated
Phase 1
A Trial Looking at Rituximab and Chemotherapy as a Treatment for Follicular Lymphoma in Elderly Patients Start of enrollment: 2009 Oct 01
Unknown status
Phase 3
Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma Start of enrollment: 2011 Sep 01
Completed
Phase 2
Nuvigil or Placebo in Newly Diagnosed Malignant Glioma Start of enrollment: 2010 Dec 01
Terminated
Phase 2
A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB) Start of enrollment: 2013 May 06
Completed
Phase 2
Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases Start of enrollment: 2014 Oct 09
Terminated
Phase 1
Avelumab With Radiotherapy in Patients With Leptomeningeal Disease Start of enrollment: 2019 Jun 10
Active, not recruiting
Phase 1
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma Start of enrollment: 2019 Jul 30
Recruiting
Phase 2, Phase 3
Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease Start of enrollment: 2020 Dec 10
Recruiting
Phase 1, Phase 2
Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases Start of enrollment: 2021 Nov 30
Recruiting
Phase 1, Phase 2
Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases Start of enrollment: 2023 Jun 06
Active, not recruiting
Early Phase 1
Pembrolizumab Plus Bevacizumab for Treatment of Brain Metastases in Metastatic Melanoma or Non-small Cell Lung Cancer Start of enrollment: 2016 May 01
Recruiting
Phase 2
A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV) Start of enrollment: 2023 Aug 22
Recruiting
Phase 1
Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer Start of enrollment: 2022 Dec 19
Recruiting
Phase 2
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Ex Vivo Culture of Circulating Tumor Cells in the Cerebral Spinal Fluid from Melanoma Patients to Study Melanoma-Associated Leptomeningeal Disease.
Vincent Law, Inna Smalley, Brittany R Evernden, Margaret Baldwin, Keiran S M Smalley, Peter A Forsyth> ;Journal of Visualized Experiments. 2024 Mar 29
Factors associated with overall survival in breast cancer patients with leptomeningeal disease (LMD): a single institutional retrospective review.
Ronak Kundalia, Ethan Vallebuona, Biwei Cao, Youngchul Kim, Inna Smalley, Gerald Wallace, Peter Forsyth, Aixa Soyano, Yolanda Pina> ;Breast Cancer Research. 2024 Mar 29
Virtual multi-institutional tumor board: a strategy for personalized diagnoses and management of rare CNS tumors.
James L Rogers, Thomas Wall, Alvina A Acquaye-Mallory, Lisa Boris, Yeonju Kim, Kenneth Aldape, Martha M Quezado, John A Butman, James G Smirniotopoulos, Huma Chaudhry,...> ;Journal of Neuro-Oncology. 2024 Apr 1
Clinical outcomes of melanoma brain metastases treated with nivolumab and ipilimumab alone versus nivolumab and ipilimumab with stereotactic radiosurgery.
Tang, J., Liu, J., Mills, M., Nakashima, J., Dohm, A., Khushalani, N., Forsyth, P., Vogelbaum, M., Wuthrick, E., Yu, H., Oliver, D., Ahmed, K.> ;Journal of Neuro-Oncology. 2024 Feb 1
Spatial transcriptomics analysis identifies a unique tumor-promoting function of the meningeal stroma in melanoma leptomeningeal disease.
Hasan Alhaddad, Oscar E Ospina, Mariam Lotfy Khaled, Yuan Ren, Peter Forsyth, Yolanda Pina, Robert Macaulay, Vincent Law, Kenneth Y Tsai, W Douglas Cress, Brooke Fridl...> ;Biorxiv. 2023 Dec 19
Branched-chain keto acids promote an immune-suppressive and neurodegenerative microenvironment in leptomeningeal disease.
Khaled, M., Ren, Y., Kundalia, R., Alhaddad, H., Chen, Z., Wallace, G., Evernden, B., Ospina, O., Hall, M., Liu, M., Darville, L., Izumi, V., Chen, Y., Pilon-Thomas, S...> ;Biorxiv. 2023 Dec 18
Differential requirements for CD4+ T cells in the efficacy of the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank and brain metastasis models.
Phadke, M., Li, J., Chen, Z., Rodriguez, P., Mandula, J., Karapetyan, L., Forsyth, P., Chen, Y., Smalley, K.> ;Journal for Immunotherapy of Cancer. 2023 Dec 6
HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis.
Michael F Emmons, Richard L Bennett, Alberto Riva, Kanchan Gupta, Larissa Anastasio Da Costa Carvalho, Chao Zhang, Robert Macaulay, Daphne Dupéré-Richér, Bin Fang, Edw...> ;Nature Communications. 2023 Nov 29
1 citations
Leptomeningeal disease in melanoma: An update on the developments in pathophysiology and clinical care.
Inna Smalley, Adrienne Boire, Priscilla Brastianos, Harriet M Kluger, Eva Hernando-Monge, Peter A Forsyth, Kamran A Ahmed, Keiran S M Smalley, Sherise Ferguson, Michae...> ;Pigment Cell & Melanoma Research. 2024 Jan 1
1 citations
Tucatinib and stereotactic radiosurgery in the management of HER2 positive breast cancer brain metastases.
Vaseem M Khatri, Matthew N Mills, Daniel E Oliver, Hsiang-Hsuan Michael Yu, Michael A Vogelbaum, Peter A Forsyth, Hatem H Soliman, Hyo S Han, Kamran A Ahmed> ;Journal of Neuro-Oncology. 2023 Aug 1
Factors improving overall survival in breast cancer patients with leptomeningeal disease (LMD): A single institutional retrospective review.
Gerald Wallace, Ronak Kundalia, Biwei Cao, Youngchul Kim, Inna Smalley, Peter Forsyth, Aixa Soyano, Yolanda Pina> ;Research Square. 2023 Jun 8
A Brain, A Heart, and the Courage: Balancing Benefit and Toxicity of Immunotherapy in Melanoma.
Yen-Chou Chen, Muhammad Jaffer, Lylybell Zhou, Javid Moslehi, Peter A Forsyth, Leslie A Fecher> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2023 May 1
3 citations
Leptomeningeal Disease (LMD) in Patients with Melanoma Metastases.
Mariam Lotfy Khaled, Ahmad A Tarhini, Peter A Forsyth, Inna Smalley, Yolanda Piña> ;Cancers. 2023 Mar 21
4 citations
Clinical outcomes of non-small cell lung cancer brain metastases treated with stereotactic radiosurgery and immune checkpoint inhibitors, EGFR tyrosine kinase inhibito...
Ammoren E Dohm, Joseph D Tang, Matthew N Mills, Casey L Liveringhouse, Maria L Sandoval, Bradford A Perez, Timothy J Robinson, Benjamin C Creelan, Jhanelle E Gray, Arn...> ;Journal of Neurosurgery. 2022 Nov 11
2 citations
Patient satisfaction and cost savings analysis of the telemedicine program within a neuro-oncology department.
James K C Liu, Richard Kang, Arkady Bilenkin, Rachel Prorok, Junmin Whiting, Krupal B Patel, Andre Beer-Furlan, Cristina Naso, Andrea Rogers, Xavier Baez Castro, Edwin...> ;Journal of Neuro-Oncology. 2022 Nov 1
26 citations
Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses.
Jessica K Mandula, Shiun Chang, Eslam Mohamed, Rachel Jimenez, Rosa A Sierra-Mondragon, Darwin C Chang, Alyssa N Obermayer, Carlos M Moran-Segura, Satyajit Das, Julio ...> ;Cancer Cell. 2022 Oct 10
3 citations
Training cancer caregiver navigators: experiences from implementing the eSNAP and caregiver navigator intervention.
Maija Reblin, Heraldo D'Almeida, Veronica Barrios-Monroy, Rachael McCormick, Laura Rodriguez, Kerie Walters, Steven K Sutton, Bradley Zebrack, Peter Forsyth, Margaret ...> ;Supportive Care in Cancer. 2022 Dec 1
4 citations
Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities.
Alcida Karz, Maya Dimitrova, Kevin Kleffman, Christopher Alvarez-Breckenridge, Michael B Atkins, Adrienne Boire, Marcus Bosenberg, Priscilla Brastianos, Daniel P Cahil...> ;Pigment Cell & Melanoma Research. 2022 Nov 1
1 citations
Surgical and anatomic factors predict development of leptomeningeal disease in patients with melanoma brain metastases.
Stephen R Lowe, Christopher P Wang, Amanda Brisco, Junmin Whiting, John Arrington, Kamran Ahmed, Michael Yu, Timothy Robinson, Daniel Oliver, Arnold Etame, Nam Tran, A...> ;Neuro-Oncology. 2022 Aug 1
4 citations
Addressing a critical need for caregiver support in neuro-oncology: development of a caregiver navigation intervention using eSNAP social resource visualization.
Maija Reblin, Kristen J Wells, Amy Otto, Rachael McCormick, Laura Rodriguez, Kerie Walters, Steven K Sutton, Bradley Zebrack, Peter Forsyth, Margaret M Byrne> ;Supportive Care in Cancer. 2022 Jun 1
7 citations
Evolving management of HER2+ breast cancer brain metastases and leptomeningeal disease.
Matthew N Mills, Whitney King, Aixa Soyano, Yolanda Pina, Brian J Czerniecki, Peter A Forsyth, Hatem Soliman, Hyo S Han, Kamran A Ahmed> ;Journal of Neuro-Oncology. 2022 Apr 1
10 citations
Emerging Systemic Treatment Perspectives on Brain Metastases: Moving Toward a Better Outlook for Patients.
Christopher Alvarez-Breckenridge, Jordi Remon, Yolanda Piña, Edwin Nieblas-Bedolla, Peter Forsyth, Lizza Hendriks, Priscilla K Brastianos> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2022 Apr 1
Revisiting the Concept of Recurrence of Primary Central Nervous System Lymphomas After Complete Response to Methotrexate-Based Therapy: Periventricular Reseeding as th...
Tugce Kutuk, G Daniel Grass, Daniel Oliver, Sepideh Mokhtari, Solmaz Sahebjam, Sungjune Kim, Jose Penagaricano, Hsiang-Hsuan Michael Yu, Nam Tran, Arnold Etame, Jennif...> ;Advances in Radiation Oncology. 2022 Mar 9
5 citations
A preclinical model of patient-derived cerebrospinal fluid circulating tumor cells for experimental therapeutics in leptomeningeal disease from melanoma.
Vincent Law, Zhihua Chen, Francesca Vena, Inna Smalley, Robert Macaulay, Brittany R Evernden, Nam Tran, Yolanda Pina, John Puskas, Gisela Caceres, Simon Bayle, Joseph ...> ;Neuro-Oncology. 2022 Oct 3
10 citations
Prospective validation of a new imaging scorecard to assess leptomeningeal metastasis: A joint EORTC BTG and RANO effort.
Emilie Le Rhun, Patrick Devos, Sebastian Winklhofer, Hafida Lmalem, Dieta Brandsma, Priya Kumthekar, Antonella Castellano, Annette Compter, Frederic Dhermain, Enrico F...> ;Neuro-Oncology. 2022 Oct 3
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Press Mentions

Molecular Characteristics of Leptomeningeal Melanoma MetastasesJanuary 10th, 2020
Molecular Characteristics of Leptomeningeal Melanoma MetastasesJanuary 10th, 2020
Shop TalkOctober 20th, 2019
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