PeterJSiekmeierMDMS

PubMed

• 1 citations
  An in Silico, Biomarker-Based Method for the Evaluation of Virtual Neuropsychiatric Drug Effects.
  Peter J. Siekmeier> ;Neural Computation. 2017 Mar 23
• 7 citations
  Computational modeling of psychiatric illnesses via well-defined neurophysiological and neurocognitive biomarkers.
  Peter J. Siekmeier> ;Neuroscience and Biobehavioral Reviews. 2015 Oct 1
• 4 citations
  Dopaminergic Contributions to Hippocampal Pathophysiology in Schizophrenia: A Computational Study
  Peter J. Siekmeier, David P. vanMaanen> ;Neuropsychopharmacology. 2014 Jan 28
• 15 citations
  Development of Antipsychotic Medications with Novel Mechanisms of Action Based on Computational Modeling of Hippocampal Neuropathology
  Peter J. Siekmeier, David P. vanMaanen> ;Plos One. 2013 Mar 19
• 36 citations
  Patterns of spontaneous magnetoencephalographic activity in patients with schizophrenia.
  Peter J. Siekmeier, Steven M. Stufflebeam> ;Journal of Clinical Neurophysiology. 2010 Jun 1
• 7 citations
  Evidence of multistability in a realistic computer simulation of hippocampus subfield CA1
  Peter J. Siekmeier> ;Behavioural Brain Research. 2009 Jun 8
• 134 citations
  Modeling GABA Alterations in Schizophrenia: A Link Between Impaired Inhibition and Altered Gamma and Beta Range Auditory Entrainment
  Dorea Vierling-Claassen, Peter J. Siekmeier, Steven M. Stufflebeam, Nancy Kopell> ;Journal of Neurophysiology. 2008 Feb 20
• 30 citations
  Modeling of context-dependent retrieval in hippocampal region CA1: implications for cognitive function in schizophrenia.
  Peter J. Siekmeier, Michael E. Hasselmo, Marc W. Howard, Joseph T. Coyle> ;Schizophrenia Research. 2007 Jan 1
• 27 citations
  Enhanced semantic priming in schizophrenia: a computer model based on excessive pruning of local connections in association cortex.
  Peter J. Siekmeier, Ralph E. Hoffman> ;The British Journal of Psychiatry. 2002 Apr 1
• 5 citations
  Design for a bioreactor with sunlight supply and operations systems for use in the space environment.
  Kei Mori, Haruhiko Ohya, Kanji Matsumoto, Hiroyuki Furuune, Kyôko Isozaki, Peter J. Siekmeier> ;Advances in Space Research. 1989 Jan 1
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Abstracts/Posters

• Increased beta-gamma power ratio in MEG auditory steady-state responses: A potential biomarker for chronic schizophrenia
  Siekmeier, P.J., Stufflebeam, S.M., Spencer, S.K., Hamalainen, M., McCarley, R., Neuropsychopharmacology, 12/10/2014
• Treatment of dopaminergic dysfunction in schizophrenia using non-dopaminergic mechanisms: A computational modeling approach
  Siekmeier, P.J. and vanMaanen, D.P., Neuropsychopharmacology, 12/9/2013
• Novel EEG biomarkers for the a priori identification of responders to the experimental antipsychotic agen pomaglumetad methionil
  Siekmeier, P.J. and Lowen, S.B., Neuropsychopharmacology, Florida, 12/11/2019
• Computational modeling of hippocampus in schizophrenia and novel antipsychotic development
  Siekmeier, P.J. and vanMaanen, D.P., Neuropsychopharmacology, 12/3/2012
• Computational modeling of prefrontal cortex neuropathology in schizophrenia
  Shaskan, N. K., Woo, T., Siekmeier, P., and vanMaanen, D., Neuroscience Meeting Planner, Society for Neuroscience, New Orleans, LA, 10/14/2012
• Relating neuropathological findings in hippocampus to schizophrenic symptomatology: A computational modeling approach
  Siekmeier, P.J. and VanMaanen, D., Biological Psychiatry, 5/5/2012
• Computational approach to understanding prefrontal cortex circuit deficits in schizophrenia
  Siekmeier, P.J. and Woo, W., 3rd Biennial Schizophrenia International Research Society Convention, Florence, Italy, 4/15/2012
• Modeling GABA Alterations in Schizophrenia
  Vierling-Claasen, D., Siekmeier, P., Stufflebeam, S., Kopell, N., Schizophrenia Research, 6/21/2008
• Altered GABA receptor dynamics explains abnormal rhythmic auditory neuromagnetic response in schizophrenia
  Stufflebeam, S., Vierling-Claassen, D., Lin, F-H., Siekmeier, P., Hamalainen, M., Kopell, N., McCarley, R., Proceedings of the 15 th International Conference on Biomagnetism, Vancouver, British Columbia, Canada, 8/22/2006
• The use of an attractor neural network model to explore normal brain function and the pathogenesis of schizophrenia
  Siekmeier, P.J., Yale Journal of Biology and Medicine, 5/1/1997
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Other

• Apparatuses and methods for identification and treatment of patients responsive to antipsychotic agent therapy. WO Patent Application No. PCT/US2020/49194. 
  P. J. Siekmeier, S.B. Lowen, and J.T. Coyle
  https://patentimages.storage.googleapis.com/eb/a4/a9/7fbc05f4a335c2/WO2021046215A1.pdf
  9/3/2020
• Method of increasing cognitive function with glutamate receptor agonist. WO Patent Application No. PCT/US2020/49283. 
  P. Siekmeier, S. Lowen, and J.T. Coyle.
  https://patentimages.storage.googleapis.com/d0/97/bc/3b8faf78d14b41/WO2021046273A1.pdf
  9/3/2020
• Systems and methods for modeling and predicting effective treatments for schizophrenia and other disorders. U.S. Patent No. 10,720,242. 
  P. Siekmeier, McLean Hospital assignee
  https://patentimages.storage.googleapis.com/60/b7/7c/a9d737b20ebfbe/US10720242.pdf
  7/21/2020
• Methods and systems for drug screening and computational modeling based on biologically realistic neurons. U.S. Patent No. 7,945,392. 
  P. Siekmeier and S. Matthysse
  https://patentimages.storage.googleapis.com/34/1c/ec/c64279efed5185/US7945392.pdf
  5/17/2011
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