PhillipPaulMinarMD

PubMed

• Precise infliximab exposure and pharmacodynamic control to achieve deep remission in paediatric Crohn's disease (REMODEL-CD): study protocol for a multicentre, open-la...
  Ruben J Colman, Nanhua Zhang, Tomoyuki Mizuno, Alexander A Vinks, Phillip Paul Minar> ;BMJ Open. 2024 Mar 25
• High Body Mass Index and Response to Anti-Tumor Necrosis Factor Therapy in Pediatric Crohn's Disease.
  Dawn R Ebach, Traci W Jester, Joseph A Galanko, Ann M Firestine, Rana Ammoury, Jose Cabrera, Julie Bass, Phillip Minar, Kelly Olano, Peter Margolis, Kelly Sandberg, Ti...> ;The American Journal of Gastroenterology. 2024 Mar 28
• Infliximab Monotherapy vs Combination Therapy for Pediatric Crohn's Disease Exhibit Similar Pharmacokinetics.
  Vuijk, S., Mathôt, R., Van Limbergen, J., Jongsma, M., Schreurs, M., de Ridder, L., D'Haens, G., Colman, R., Minar, P.> ;Inflammatory Bowel Diseases. 2024 Jan 3
• Acute pancreatitis is associated with gut dysbiosis in children.
  Chinenye R Dike, Nicholas J Ollberding, Tyler Thompson, Nicole Kotha, Phillip Minar, David S Vitale, Tom K Lin, Alexander Nasr, Lee A Denson, David B Haslam, Maisam Ab...> ;Digestive and Liver Disease. 2024 Mar 1
• 2 citations
  Precision Dosing of Anti-TNF Therapy in Pediatric Inflammatory Bowel Disease.
  Abigail Samuels, Kaitlin G Whaley, Phillip Minar> ;Current Gastroenterology Reports. 2023 Nov 1
• The Role of Therapeutic Drug Monitoring in Children.
  Alexander Nasr, Phillip Minar> ;Gastroenterology Clinics of North America. 2023 Sep 1
• 2 citations
  Racial Disparities in Pediatric Inflammatory Bowel Disease Care: Differences in Outcomes and Health Service Utilization Between Black and White Children.
  Julia Smith, Chunyan Liu, Andrew Beck, Lin Fei, Cole Brokamp, Syeda Meryum, Kaitlin G Whaley, Phillip Minar, Jennifer Hellmann, Lee A Denson, Peter Margolis, Jasbir Dh...> ;The Journal of Pediatrics. 2023 Sep 1
• 14 citations
  Comparative Effectiveness of Anti-TNF in Combination With Low-Dose Methotrexate vs Anti-TNF Monotherapy in Pediatric Crohn's Disease: A Pragmatic Randomized Trial.
  Michael D Kappelman, David A Wohl, Hans H Herfarth, Ann M Firestine, Jeremy Adler, Rana F Ammoury, Jeanine E Aronow, Dorsey M Bass, Julie A Bass, Keith Benkov, Catalin...> ;Gastroenterology. 2023 Jul 1
• Editorial: achievements and unresolved questions in improving the pharmacokinetics of vedolizumab in adolescents with inflammatory bowel disease-authors' reply.
  Ruben J Colman, Phillip Minar> ;Alimentary Pharmacology & Therapeutics. 2023 Mar 1
• 1 citations
  Transcriptome analysis in acute gastrointestinal graft-host disease reveals a unique signature in children and shared biology with pediatric inflammatory bowel disease.
  Pooja Khandelwal, Dana T Lounder, Allison Bartlett, Yael Haberman, Anil G Jegga, Sudhir Ghandikota, Jane Koo, Nathan Luebbering, Daniel Leino, Sheyar Abdullah, Michael...> ;Haematologica. 2023 Jul 1
• 4 citations
  Model-informed Precision Dosing for Biologics Is Now Available at the Bedside for Patients With Inflammatory Bowel Disease.
  Ruben J Colman, Abigail Samuels, Tomoyuki Mizuno, Nieko Punt, Alexander A Vinks, Phillip Minar> ;Inflammatory Bowel Diseases. 2023 Aug 1
• 7 citations
  Real world population pharmacokinetic study in children and young adults with inflammatory bowel disease discovers novel blood and stool microbial predictors of vedoli...
  Ruben J Colman, Tomoyuki Mizuno, Keizo Fukushima, David B Haslam, Jeffrey S Hyams, Brendan Boyle, Joshua D Noe, Geert R D'Haens, Johan Van Limbergen, Kelly Chun, Jane ...> ;Alimentary Pharmacology & Therapeutics. 2023 Mar 1
• Pilot trial of iBDecide: Evaluating an online tool to facilitate shared decision making for adolescents and young adults with ulcerative colitis.
  Kelly A Matula, Philip Minar, Nancy M Daraiseh, Li Lin, Marlee Recker, Ellen A Lipstein> ;Health Expectations. 2022 Dec 1
• 7 citations
  Multicenter Cohort Study of Infliximab Pharmacokinetics and Therapy Response in Pediatric Acute Severe Ulcerative Colitis.
  Kaitlin G Whaley, Ye Xiong, Rebekah Karns, Jeffrey S Hyams, Subra Kugathasan, Brendan M Boyle, Thomas D Walters, Judith Kelsen, Neal LeLeiko, Jason Shapiro, Amanda Wad...> ;Clinical Gastroenterology and Hepatology. 2023 May 1
• 2 citations
  Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis.
  Kathryn Clarkston, Rebekah Karns, Anil G Jegga, Mihika Sharma, Sejal Fox, Babajide A Ojo, Phillip Minar, Thomas D Walters, Anne M Griffiths, David R Mack, Brendan Boyl...> ;Journal of Crohn's & Colitis. 2022 Nov 23
• 14 citations
  Antibodies-to-infliximab accelerate clearance while dose intensification reverses immunogenicity and recaptures clinical response in paediatric Crohn's disease.
  Ruben J Colman, Ye Xiong, Tomoyuki Mizuno, Jeffrey S Hyams, Joshua D Noe, Brendan Boyle, Geert R D'Haens, Johan van Limbergen, Kelly Chun, Jane Yang, Michael J Rosen, ...> ;Alimentary Pharmacology & Therapeutics. 2022 Mar 1
• 1 citations
  Quality Improvement Methodology Optimizes Infliximab Levels in Pediatric Patients with Inflammatory Bowel Disease.
  Jennifer Hellmann, Renee K Etter, Lee A. Denson, Phillip Minar, Denise Hill, Dana M. H. Dykes, Michael J. Rosen> ;Pediatric Quality & Safety. 2021 May 5
• 16 citations
  Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease.
  Heyman, M. B., , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Journal of Crohn's & Colitis. 2021 Feb 1
• 31 citations
  Real-World Infliximab Pharmacokinetic Study Informs an Electronic Health Record-Embedded Dashboard to Guide Precision Dosing in Children with Crohn's Disease.
  Ye Xiong, Tomoyuki Mizuno, Ruben J. Colman, Jeffrey S. Hyams, Joshua D. Noe, Brendan M. Boyle, Yi-Ting Tsai, Min Dong, Kimberly Jackson, Nieko Punt, Michael J. Rosen, ...> ;Clinical Pharmacology and Therapeutics. 2021 Jun 1
• 13 citations
  Achieving Target Infliximab Drug Concentrations Improves Blood and Fecal Neutrophil Biomarkers in Crohn's Disease.
  Ruben J. Colman, Yi-Ting Tsai, Kimberly Jackson, Brendan M. Boyle, Joshua D. Noe, Jeffrey S. Hyams, Geert R. D'Haens, Johan Van Limbergen, Michael J. Rosen, Lee A. Den...> ;Inflammatory Bowel Diseases. 2021 Jun 15
• 3 citations
  The Gray Zone: Adolescent and Young Adult Decision Support Needs for Ulcerative Colitis.
  Andrea R. Meisman, Nancy M. Daraiseh, Phil Minar, Marlee Saxe, Ellen A. Lipstein> ;MDM Policy & Practice. 2020 Jul 7
• 15 citations
  Favorable Outcomes and Anti-TNF Durability After Addition of an Immunomodulator for Anti-Drug Antibodies in Pediatric IBD Patients.
  Ruben J. Colman, Andrea Portocarrero-Castillo, Deepika L. Chona, Jennifer Hellmann, Phillip Minar, Michael J. Rosen> ;Inflammatory Bowel Diseases. 2021 Mar 15
• A Micro-longitudinal Approach to Measuring Medication Adherence in Pediatric Inflammatory Bowel Diseases.
  Jill M. Plevinsky, Lee A. Denson, Jenny Hellmann, Phillip Minar, Michael J. Rosen, Kevin A. Hommel> ;Journal of Pediatric Gastroenterology and Nutrition. 2020 Sep 1
• 24 citations
  Elevated Pretreatment Plasma Oncostatin M Is Associated With Poor Biochemical Response to Infliximab.
  Phillip Minar, Christina N. Lehn, Yi-Ting Tsai, Kimberly Jackson, Michael J. Rosen, Lee A. Denson> ;Crohn's & Colitis 360. 2019 Aug 19
• 1 citations
  Implementing a Novel Quality Improvement-Based Approach to Data Quality Monitoring and Enhancement in a Multipurpose Clinical Registry.
  Jesse Pratt, Daniel Jeffers, Eileen C. King, Michael D. Kappelman, Jennifer Collins, Peter A. Margolis, Howard I. Baron, Julie A. Bass, Mikelle D. Bassett, Genie L. Be...> ;EGEMS. 2019 Sep 30
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