
Pier Paolo Peruzzi MD PhD, FAANS
Brain & Spinal Tumor
Assistant Professor
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60 Fenwood Rd#4186Boston, MA 02115
Phone+1 617-525-6454
Fax+1 617-713-3050
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Summary
- Dr. Pier Paolo Peruzzi is a neurosurgeon in Boston, MA and is affiliated with Brigham and Women's Hospital. He received his medical degree from La Sapienza University of Rome and has been in practice 13 years. He also speaks multiple languages, including Italian. He specializes in brain & spinal tumors. Dr Peruzzi is a NIH-sponsored researcher and his laboratory investigates the role and therapeutic use of non-coding RNAs in malignant brain tumors. He is also the principal investigator of a clinical trial investigating the use of drug-releasing micro devices informing personalized chemotherapy for patients affected by gliomas.
Education & Training
Ohio State University HospitalResidency, Neurological Surgery, 2007 - 2014
Sapienza University of RomeClass of 2004
Certifications & Licensure
MA State Medical License 2015 - 2028
OH State Medical License 2007 - 2016
American Board of Neurological Surgery Neurological Surgery
Awards, Honors, & Recognition
- Academy Award American Academy of Neurological Surgery, 2018
- NREF research fellowship American Association of Neurological Surgeons, 2011
- R25 fellowship NIH, 2010
Clinical Trials
- Implantable Microdevice In Primary Brain Tumors Start of enrollment: 2020 Mar 03
Publications & Presentations
PubMed
- scAAV-based NeuroD1 gene therapy inhibiting glioblastoma growth.Debora Mazzetti, Pier Paolo Peruzzi, Himanshu Soni
Molecular Therapy. Oncology. 2026-09-17 - 1 citationsTreatment Effect Reanalysis of the Randomized Individual Screening Trial of Innovative Glioblastoma Therapy in Newly Diagnosed Glioblastoma With External Control Data.Tulika Rudra Gupta, Mei-Yin C Polley, Robert Redd, Eudocia Q Lee, Isabel Arrillaga-Romany
Journal of Clinical Oncology. 2026-07-20 - Anticoagulation Following Surgery for Glioblastoma: Case Report and Review of the Literature.Zade Akras, David I Nawabi, Noah L A Nawabi, Adam Glaser, Lennard Spanehl
Journal of Neurological Surgery Reports. 2026-07-01
Press Mentions
The Hitchhiker's Guide to Defeating GlioblastomaJanuary 25th, 2019
Grant Support
- Using implantable microdevices for deep phenotyping of multiple drug responses in brain tumor patientsBRIGHAM AND WOMEN'S HOSPITAL2023–2028
- Using implantable microdevices for deep phenotyping of multiple drug responses in brain tumor patientsBRIGHAM AND WOMEN'S HOSPITAL2023–2028
- Harnessing Artificial MicroRNA Clusters Against Glioblastoma Epigenetic Plasticity and Resistance to TherapyBRIGHAM AND WOMEN'S HOSPITAL2020–2026
- Characterization of a microRNA network regulating glioblastoma epigenetics, cell reprogramming and DNA repairNINDS2017–2022
- Characterizing miR-128 as a major regulator of epigenetic programming, and a potent sensitizer to radiation therapy in glioblastoma.NINDS2016–2018
Committees
- Member, Internal Review Board for Neuro-oncology DFCI/HMS Cancer Center 2020 - Present
- Member, Scientific Review Committee at DFCI 2019 - Present
Professional Memberships
- Member
Other Languages
- Italian
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