PinelopiKapitsinouMD

PubMed

• Post-ischemic inactivation of HIF prolyl hydroxylases in endothelium promotes maladaptive kidney repair by inducing glycolysis.
  Ratnakar Tiwari, Rajni Sharma, Ganeshkumar Rajendran, Gabriella S Borkowski, Si Young An, Michael Schonfeld, James O'Sullivan, Matthew J Schipma, Yalu Zhou, Guillaume ...> ;Biorxiv. 2023 Oct 3
• 1 citations
  Chemical inhibition of oxygen-sensing prolyl hydroxylases impairs angiogenic competence of human vascular endothelium through metabolic reprogramming.
  Ratnakar Tiwari, Prashant V Bommi, Peng Gao, Matthew J Schipma, Yalu Zhou, Susan E Quaggin, Navdeep S Chandel, Pinelopi P Kapitsinou> ;Iscience. 2022 Oct 21
• 6 citations
  Role of Endothelial Prolyl-4-Hydroxylase Domain Protein/Hypoxia-Inducible Factor Axis in Acute Kidney Injury.
  Ratnakar Tiwari, Pinelopi P. Kapitsinou> ;Nephron. 2021 Sep 1
• 22 citations
  Hypoxic preconditioning protects against ischemic kidney injury through the IDO1/kynurenine pathway
  Rafael Torosyan, Shengping Huang, Prashant V. Bommi, Ratnakar Tiwari, Si Young An, Michael Schonfeld, Ganeshkumar Rajendran, Matthew A. Kavanaugh, Benjamin Gibbs, Agni...> ;Cell Reports. 2021 Aug 17
• 97 citations
  Iron Deficiency in Chronic Kidney Disease: Updates on Pathophysiology, Diagnosis, and Treatment.
  Elizabeth Katherine Batchelor, Pinelopi P. Kapitsinou, Pablo E. Pergola, Csaba P. Kovesdy, Diana I. Jalal> ;Journal of the American Society of Nephrology. 2020 Feb 10
• 16 citations
  Tissue-specific Fixation Methods Are Required for Optimal In Situ Visualization of Hyaluronan in the Ovary, Kidney, and Liver.
  Jennifer E. Rowley, Gillian E. Rubenstein, Sharrόn L. Manuel, Natalie L. Johnson, Jordan Surgnier, Pinelopi P. Kapitsinou, Francesca E. Duncan, Michele T. Pritchard> ;The Journal of Histochemistry and Cytochemistry. 2020 Jan 1
• 24 citations
  Inhibition of Endothelial PHD2 Suppresses Post-Ischemic Kidney Inflammation through Hypoxia-Inducible Factor-1.
  Ganeshkumar Rajendran, Michael Schonfeld, Ratnakar Tiwari, Shengping Huang, Rafael Torosyan, Timothy A. Fields, Jihwan Park, Katalin Susztak, Pinelopi P. Kapitsinou> ;Journal of the American Society of Nephrology. 2020 Jan 29
• 93 citations
  The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice.
  Pinelopi P. Kapitsinou, Ganeshkumar Rajendran, Lindsay Astleford, Mark Michael, Michael Schonfeld, Timothy A. Fields, Sheila Shay, Jaketa L. French, James West, Volker...> ;Molecular and Cellular Biology. 2016 May 15
• 78 citations
  Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin
  Hanako Kobayashi, Qingdu Liu, Thomas C. Binns, Andres A. Urrutia, Olena Davidoff, Pinelopi P. Kapitsinou, Andrew S. Pfaff, Hannes Olauson, Annika Wernerson, Agnes B. F...> ;The Journal of Clinical Investigation. 2016 May 2
• 59 citations
  Molecular mechanisms of ischemic preconditioning in the kidney
  Pinelopi P. Kapitsinou, Volker H. Haase> ;American Journal of Physiology. Renal Physiology. 2015 Nov 15
• 136 citations
  Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury
  Pinelopi P. Kapitsinou, Hideto Sano, Mark Michael, Hanako Kobayashi, Olena Davidoff, Aihua Bian, Bing Yao, Ming-Zhi Zhang, Raymond C. Harris, Kevin J. Duffy, Connie L....> ;The Journal of Clinical Investigation. 2014 Jun 2
• 77 citations
  Myeloid Cell-Derived Hypoxia-Inducible Factor Attenuates Inflammation in Unilateral Ureteral Obstruction-Induced Kidney Injury
  Hanako Kobayashi, Victoria Gilbert, Qingdu Liu, Pinelopi P. Kapitsinou, Travis L. Unger, Jennifer Rha, Stefano Rivella, Detlef Schlöndorff, Volker H. Haase> ;Journal of Immunology. 2012 May 15
• 90 citations
  Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury.
  Pinelopi P. Kapitsinou, Jonathan Jaffe, Mark Michael, Christina E. Swan, Kevin J. Duffy, Connie L. Erickson-Miller, Volker H. Haase> ;American Journal of Physiology. Renal Physiology. 2012 May 1
• 2 citations
  HO-1 in Control of a Self-Eating Kidney
  Pinelopi P. Kapitsinou, Volker H. Haase> ;Journal of the American Society of Nephrology. 2010 Oct 1
• 227 citations
  Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia
  Pinelopi P. Kapitsinou, Qingdu Liu, Travis L. Unger, Jennifer Rha, Olena Davidoff, Brian Keith, Jonathan A. Epstein, Sheri L. Moores, Connie L. Erickson-Miller, Volker...> ;Blood. 2010 Oct 21
• 57 citations
  Human and murine kidneys show gender- and species-specific gene expression differences in response to injury.
  Han Si, Ramandeep S. Banga, Pinelopi P. Kapitsinou, Manjunath Ramaiah, Janis Lawrence, Ganesh Kambhampati, Antje Gruenwald, Erwin P. Bottinger, Daniel Glicklich, V Tel...> ;Plos One. 2009 Mar 11
• 24 citations
  Kidney transplantation in lupus patients: A case-control study from a single centre
  Sophia Lionaki, Pinelopi P. Kapitsinou, Aliki G. Iniotaki, A Kostakis, H. M. Moutsopoulos, John Boletis> ;Lupus. 2008 Jul 1
• 117 citations
  The VHL tumor suppressor and HIF: insights from genetic studies in mice
  Pinelopi P. Kapitsinou, Volker H. Haase> ;Cell Death and Differentiation. 2008 Jan 25
• 23 citations
  Acute renal failure in an AIDS patient on tenofovir: a case report
  Pinelopi P. Kapitsinou, Naheed Ansari> ;Journal of Medical Case Reports. 2008 Mar 31
• 68 citations
  Lupus nephritis: treatment with mycophenolate mofetil
  Pinelopi P. Kapitsinou, John Boletis, Fotini N. Skopouli, Kyriaki A. Boki, Haralampos M. Moutsopoulos> ;Rheumatology. 2003 Nov 17
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Lectures

• Anemia, the Hypoxia-Inducible Factor System, and CKD 
  American Society of Nephrology Kidney Week 2019 - Washington, D.C. - 11/9/2019
• Cellular Metabolism in Kidney and Urologic Diseases 
  American Society of Nephrology Kidney Week 2019 - Washington, D.C. - 11/8/2019