Purna C Kashyap MD AGAF
Gastrointestinal Functional & Motility Disorders
Associate Professor, Medicine, Physiology and Biomedical Engineering, Mayo Clinic
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200 1st St SwRochester, MN 55905
Phone+1 507-284-2511
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Education & Training
Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Gastroenterology, 2007 - 2010
University of Texas Medical Branch HospitalsResidency, Internal Medicine, 2004 - 2007
Bangalore Medical CollegeClass of 1999
Certifications & Licensure
MN State Medical License 2007 - 2027
American Board of Internal Medicine Gastroenterology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 2 Certification Mayo Clinic Patient Lists, Mayo Clinic, 2013-2017
- CMS Meaningful Use Stage 2 Certification Mayo Clinic Electronic Notes, Mayo Clinic, 2013-2017
- CMS Meaningful Use Stage 2 Certification Centricity Patient Online, GE Healthcare, 2013-2017
Clinical Trials
- Developing Novel Microbiota-Targeted Therapies for Irritable Bowel Syndrome Start of enrollment: 2014 Sep 19
- Small Bowel Microbiota Characterization in Healthy Individuals Before and After Consumption of a Western Diet Start of enrollment: 2017 Jan 09
- Effect of Gum Arabic on Gastrointestinal Transit and Permeability Start of enrollment: 2018 Dec 18
Publications & Presentations
PubMed
- Compositional and functional differences of gut microbiome and metabolome inform pathogenesis of cholestatic liver disease.Marios Nikolaidis, Chang Hu, Brian D Juran, Bryan M McCauley, Erik M Schlicht
Gut Microbes. 2026-12-31 - Ecological and dietary strategies to constrain Clostridioides difficile.Melinda A Engevik, Aaron L Hecht, Jessica R Allegretti, Purna C Kashyap
Cell Host & Microbe. 2026-07-08 - Butyrate Regulates the Blood-Brain Barrier Transport and Intraendothelial Accumulation of Alzheimer's Disease Amyloid-Beta Peptides.Vaishnavi Veerareddy, Zengtao Wang, Purna C Kashyap, Karunya K Kandimalla
Molecular Pharmaceutics. 2026-07-06
Press Mentions
The Future Will Be Personalized: Accelerating Microbiome ResearchNovember 24th, 2022- How the Ecosystems in Our Guts Could Be Linked to Brain DisordersAugust 28th, 2021
- Mayo Clinic Analysis Shows How Disease, Diet, and Genomics Interact with Gut ViromeAugust 25th, 2021
Grant Support
- MECHANISMS OF VISCERAL PAIN DRIVEN BY SMALL INTESTINAL MICROBIOTAMAYO CLINIC ROCHESTER2023–2028
- Mechanisms of alteration of gastrointestinal physiology by gut microbesMAYO CLINIC ROCHESTER2017–2027
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