RenukaVIyerMD

Oncology • Buffalo, NY

Professor, Medicine, University at Buffalo SUNY School of Medicine & Biomedical Sciences

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Office
Elm And Carlton St
Buffalo, NY 14263
Phone+1 716-845-2300
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Education & Training

University at BuffaloFellowship, Hematology and Medical Oncology, 2001 - 2004
Lincoln Medical and Mental Health CenterResidency, Internal Medicine, 1998 - 2001
Grant Medical CollegeClass of 1995

Certifications & Licensure

NY State Medical License 2001 - 2024

Clinical Trials

Tivozanib in Treating Patients With Liver Cancer That Is Metastatic or Cannot Be Removed by Surgery Start of enrollment: 2013 Jul 11
Completed
Phase 1, Phase 2
Nintedanib in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors Start of enrollment: 2015 May 15
Completed
Phase 2
Sorafenib Tosylate and Pembrolizumab in Treating Patients With Advanced or Metastatic Liver Cancer Start of enrollment: 2017 Dec 07
Active, not recruiting
Phase 1, Phase 2
Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid Tumors Start of enrollment: 2018 Oct 26
Active, not recruiting
Phase 3
Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers Start of enrollment: 2019 Feb 07
Active, not recruiting
Phase 3
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Publications & Presentations

PubMed

YIA24-003: A Phase I Study of TAS102 Plus Talazoparib in Advanced Colorectal (CRC) and Esophagogastric (EGC) Adenocarcinomas.
Sarah Chatley, Victoria Fitzpatrick, Justin Zonneville, Mohammed Alruwaili, Hanna Rosenheck, Donald Mager, Jianxin Wang, Kristopher Attwood, Andrei Bakin, Christos Fou...> ;Journal of the National Comprehensive Cancer Network. 2024 Apr 5
Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update.
John D Gordan, Erin B Kennedy, Ghassan K Abou-Alfa, Eliza Beal, Richard S Finn, Terence P Gade, Laura Goff, Shilpi Gupta, Jennifer Guy, Hang T Hoang, Renuka Iyer, Ishm...> ;Journal of Clinical Oncology. 2024 Mar 19
A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers.
Mohammed M Alruwaili, Justin Zonneville, Maricris N Naranjo, Hannah Serio, Thomas Melendy, Robert M Straubinger, Bryan Gillard, Barbara A Foster, Priyanka Rajan, Krist...> ;Cell Reports. Medicine. 2024 Mar 19
Evaluation of the serotonin pathway as a biomarker in cholangiocarcinoma.
Christos Fountzilas, Sylvia Alarcon Velasco, Wiam Bshara, Charles M LeVea, Medhavi Gupta, Wenyan Ji, Anthony George, Kristopher Attwood, Renuka V Iyer> ;Journal of Gastrointestinal Oncology. 2023 Oct 31
2 citations
The extracellular matrix in hepatocellular carcinoma: Mechanisms and therapeutic vulnerability.
Arya Mariam Roy, Renuka Iyer, Sayan Chakraborty> ;Cell Reports. Medicine. 2023 Sep 19
15 citations
NCCN Guidelines® Insights: Biliary Tract Cancers, Version 2.2023.
Al B Benson, Michael I D'Angelica, Thomas Abrams, Daniel E Abbott, Aijaz Ahmed, Daniel A Anaya, Robert Anders, Chandrakanth Are, Melinda Bachini, David Binder, Mitesh ...> ;Journal of the National Comprehensive Cancer Network. 2023 Jul 1
5 citations
Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of gastrointestinal cancer.
Kelly, R., Bever, K., Chao, J., Ciombor, K., Eng, C., Fakih, M., Goyal, L., Hubbard, J., Iyer, R., Kemberling, H., Krishnamurthi, S., Ku, G., Mordecai, M., Morris, V.,...> ;Journal for Immunotherapy of Cancer. 2023 Jun 1
2 citations
Immunotherapy in malignant peritoneal mesothelioma (Review).
Sabah Alaklabi, Arya Mariam Roy, Joseph J Skitzki, Renuka Iyer> ;Molecular and Clinical Oncology. 2023 Apr 1
1 citations
A multicenter, phase Ib/II, open-label study of tivozanib with durvalumab in advanced hepatocellular carcinoma (DEDUCTIVE).
Sharmeen Mahmood, Daneng Li, Arielle Lee, Julie Rowe, Muhammed Beg, Vijay Kasturi, Renuka Iyer, Thomas Abrams, Farshid Dayyani> ;Future Oncology. 2022 Dec 1
1 citations
PET Imaging of Hepatocellular Carcinoma Using ZD2-(Ga-NOTA).
Olga Sergeeva, Yifan Zhang, Songqi Gao, E Ricky Chan, Maxim Sergeev, Renuka Iyer, Sandra Sexton, Norbert Avril, Zheng-Rong Lu, Zhenghong Lee> ;Journal of Hepatocellular Carcinoma. 2023 Jan 1
15 citations
Phase 1 Randomized Trial of Stereotactic Body Radiation Therapy Followed by Nivolumab plus Ipilimumab or Nivolumab Alone in Advanced/Unresectable Hepatocellular Carcin...
Aditya Juloori, Rohan R Katipally, Jeffrey M Lemons, Anurag K Singh, Renuka Iyer, Jared R Robbins, Ben George, William A Hall, Sean P Pitroda, Fauzia Arif, John Fung, ...> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Jan 1
Updates in Biliary Tract Cancers.
Daneng Li, Ya-Han Zhang, Christiana J Crook, Renuka V Iyer> ;Cancers. 2022 Jun 1
5 citations
Health-Related Quality of Life (HRQoL) in Neuroendocrine Tumors: A Systematic Review.
Rohit Gosain, Medhavi Gupta, Arya Mariam Roy, Jonathan Strosberg, Kathryn M Glaser, Renuka Iyer> ;Cancers. 2022 Mar 10
Imaging of Tumor-Associated Vascular Prostate-Specific Membrane Antigen in Woodchuck Model of Hepatocellular Carcinoma.
Olga Sergeeva, Yifan Zhang, Willian Julian, Arun Sasikumar, Amad Awadallah, Jonathan Kenyon, Wuxian Shi, Maxim Sergeev, Steve Huang, Sandra Sexton, Renuka Iyer, Wei Xi...> ;Gastro Hep Advances. 2022 Jan 1
13 citations
Mutant- and-Driven Hematopoiesis Populates the Hematopoietic Compartment in Response to Peptide Receptor Radionuclide Therapy.
Abhay Singh, Nuria Mencia-Trinchant, Elizabeth A Griffiths, Alaa Altahan, Mahesh Swaminathan, Medhavi Gupta, Matthew Gravina, Rutaba Tajammal, Mark G Faber, LunBiao Ya...> ;JCO Precision Oncology. 2022 Jan 1
5 citations
Phase Ib/II study of Cetuximab Plus Pembrolizumab in Patients with Advanced RAS wild-type Colorectal Cancer.
Christos Fountzilas, David L. Bajor, Sarbajit Mukherjee, Joel N. Saltzman, Agnieszka K. Witkiewicz, Orla Maguire, Hans Minderman, Ram Nambiar, Hanna R. Rosenheck, Erik...> ;Clinical Cancer Research. 2021 Oct 13
8 citations
A phase I study of the anaplastic lymphoma kinase inhibitor ceritinib in combination with gemcitabine-based chemotherapy in patients with advanced solid tumors.
Christos Fountzilas, Alex A. Adjei, Mateusz Opyrchal, Rachel Evans, Mohammad Ghasemi, Kristopher Attwood, Adrienne Groman, Wiam Bshara, Andrew Goey, John Wilton, Wen W...> ;International Journal of Cancer. 2021 Jul 28
5 citations
Selective therapeutic strategy for p53-deficient cancer by targeting dysregulation in DNA repair.
Justin Zonneville, Moyi Wang, Mohammed M. Alruwaili, Brandon E. Smith, Megan Melnick, Kevin H. Eng, Thomas Melendy, Ben Ho Park, Renuka Iyer, Christos Fountzilas, Andr...> ;Communications Biology. 2021 Jul 12
2 citations
Detection of Hepatocellular Carcinoma in a High-Risk Population by a Mass Spectrometry-Based Test.
Devalingam Mahalingam, Leonidas Chelis, Imran Nizamuddin, Sunyoung S. Lee, Stylianos Kakolyris, Glenn A. Halff, Kenneth Washburn, Kristopher Attwood, Ibnshamsah Fahad,...> ;Cancers. 2021 Jun 22
406 citations
Hepatobiliary cancers, Version 2.2021
Al B. Benson, Michael I. D’Angelica, Daniel E. Abbott, Daniel A. Anaya, Robert A. Anders, Chandrakanth Are, Melinda Bachini, Mitesh J. Borad, Daniel B. Brown, Adam M. ...> ;Journal of the National Comprehensive Cancer Network. 2021 May 1
16 citations
Targeting the NTRK Fusion Gene in Pancreatic Acinar Cell Carcinoma: A Case Report and Review of the Literature.
Medhavi Gupta, Christopher Sherrow, Maghan E. Krone, Edik M. Blais, Michael J. Pishvaian, Emanuel F. Petricoin, Lynn M. Matrisian, Patricia DeArbeloa, Gary Gregory, Al...> ;Journal of the National Comprehensive Cancer Network. 2021 Jan 6
Immunotherapy in hepatocellular cancer.
Christos Fountzilas, Rachel Evans, Sabah Alaklabi, Renuka Iyer> ;Advances in Cancer Research. 2021 Jan 1
11 citations
Phase Ib Study of Enzalutamide with or Without Sorafenib in Patients with Advanced Hepatocellular Carcinoma.
James J. Harding, Robin Kate Kelley, Benjamin R. Tan, Marinela Capanu, Gian Kinh Do, Jinru Shia, Joanne F. Chou, Christine S. Ferrer, Chayma Boussayoud, Kerri E. Muenk...> ;The Oncologist. 2020 Dec 1
304 citations
Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline
John D. Gordan, Erin B. Kennedy, Ghassan K. Abou-Alfa, Muhammad Shaalan Beg, Steven Brower, Terence P. Gade, Laura W. Goff, Shilpi Singh Gupta, Jennifer File Guy, Will...> ;Journal of Clinical Oncology. 2020 Nov 16
3 citations
Liver background uptake of [ 18 F]FLT in PET imaging
Olga A. Sergeeva, Yifan Zhang, Jonathan Kenyon, Galen A. Miller-Atkins, Maxim Sergeev, Emily Verbus, Renuka Iyer, Sandra Sexton, Vladimir Kepe, Norbert Avril, Yogen Sa...> ;American Journal of Nuclear Medicine and Molecular Imaging. 2020 Oct 15
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Hospital Affiliations

Roswell Park Comprehensive Cancer CenterBuffalo, New York