RobertM.CooperMD

Pediatric Hematology & Oncology • Los Angeles, CA

Physician

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Office
4950 Sunset Blvd
Los Angeles, CA 90027
Phone+1 323-783-5307
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Summary

Board Certified in Pediatric Hematology/Oncology
Principal Investigator COG trials 2005 - present
Chief of Pediatric Hematology/Oncology Southern California Permanente Medical group 2005- present
Chair of Administrative Cancer Committee and Physician Director Cancer program KP Los Angeles Medical Center 2012- present
Research Interests include Cancer Care Delivery, Disparities outcomes in Cancer, Clinical trials management

Education & Training

Children's Hospital Los AngelesFellowship, Pediatric Hematology/Oncology, 1993 - 1996
Tufts Medical CenterResidency, Pediatrics, 1989 - 1992
Eastern Virginia Medical SchoolClass of 1989

Certifications & Licensure

CA State Medical License 1993 - 2025
UT State Medical License 1992 - 1996
CO State Medical License 1993 - 1993
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing's Sarcoma Start of enrollment: 2001 Feb 01
Unknown status
Phase 3
Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma Start of enrollment: 2001 Oct 18
Active, not recruiting
Phase 3
Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk Rhabdomyosarcoma Start of enrollment: 2004 Sep 04
Completed
Phase 3
Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors Start of enrollment: 2004 Mar 25
Recruiting
Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma Start of enrollment: 2004 Apr 01
Active, not recruiting
Phase 3
Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma Start of enrollment: 2005 Nov 14
Completed
Phase 3
Study to Assess Compliance With Long-Term Mercaptopurine Treatment in Young Patients With Acute Lymphoblastic Leukemia in Remission Start of enrollment: 2005 May 30
Completed
Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal Cancer Start of enrollment: 2006 Feb 20
Completed
Phase 3
Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor Start of enrollment: 2007 May 03
Completed
Phase 3
Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors Start of enrollment: 2006 Jun 01
Completed
Phase 2
Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma Start of enrollment: 2007 Aug 06
Active, not recruiting
Phase 3
Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' Tumor Start of enrollment: 2006 Nov 06
Active, not recruiting
Phase 3
Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma Start of enrollment: 2006 Dec 26
Completed
Phase 3
Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes Start of enrollment: 2007 Mar 01
Completed
Phase 3
Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia Start of enrollment: 2007 Mar 01
Completed
Phase 1, Phase 2
Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed Stage III or Stage IV Wilms' Tumor Start of enrollment: 2007 Feb 26
Active, not recruiting
Phase 3
Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia Start of enrollment: 2007 Mar 01
Completed
Phase 3
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Start of enrollment: 2007 Jan 22
Active, not recruiting
Phase 3
Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia Start of enrollment: 2007 Jan 01
Completed
Assessing Ear Damage in Young Cancer Patients Treated With Cisplatin Start of enrollment: 2007 May 01
Completed
Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radiation Therapy in Treating Young Patients With Extraocular Retinoblastoma Start of enrollment: 2008 Feb 04
Active, not recruiting
Phase 3
Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2008 Jan 15
Active, not recruiting
Phase 3
Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System Start of enrollment: 2009 Feb 10
Completed
Phase 3
Bortezomib and Combination Chemotherapy in Treating Younger Patients With Recurrent, Refractory, or Secondary Acute Myeloid Leukemia Start of enrollment: 2008 Apr 01
Completed
Phase 2
Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy Start of enrollment: 2008 Jun 23
Completed
Phase 3
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies Start of enrollment: 2008 Jul 17
Recruiting
Neuropsychological and Behavioral Testing in Younger Patients With Cancer Start of enrollment: 2009 Feb 27
Recruiting
Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors Start of enrollment: 2009 Jan 01
Completed
Phase 2
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia Start of enrollment: 2009 Mar 09
Completed
Phase 3
Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Start of enrollment: 2009 Mar 01
Completed
Phase 2
Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma Start of enrollment: 2006 Sep 25
Completed
Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer Start of enrollment: 2003 Oct 13
Completed
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
Recruiting
Collecting and Storing Tissue From Young Patients With Cancer Start of enrollment: 2007 Mar 05
Recruiting
Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma Start of enrollment: 2008 Feb 04
Completed
Collecting and Storing Biological Samples From Patients With Ewing Sarcoma Start of enrollment: 2008 Feb 04
Completed
Collecting and Storing Biological Samples From Young Patients With Hodgkin?s Lymphoma Start of enrollment: 2006 Oct 23
Completed
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Start of enrollment: 2000 Nov 06
Recruiting
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Start of enrollment: 1999 Mar 15
Completed
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors Start of enrollment: 2004 Feb 16
Completed
Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor Start of enrollment: 2009 Jul 13
Active, not recruiting
Phase 3
Study of Blood Samples From Newborns With Down Syndrome Start of enrollment: 2009 Feb 23
Completed
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 14
Active, not recruiting
Phase 3
Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma Start of enrollment: 2005 May 30
Completed
Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma Start of enrollment: 2010 Jan 01
Completed
Phase 2
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma Start of enrollment: 2010 May 07
Active, not recruiting
Phase 3
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia Start of enrollment: 2011 Feb 01
Completed
Phase 2
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors Start of enrollment: 2010 Nov 22
Completed
Phase 2
Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma Start of enrollment: 2010 Oct 01
Completed
Phase 2
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Start of enrollment: 2010 Nov 22
Active, not recruiting
Phase 3
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia Start of enrollment: 2011 Apr 04
Completed
Phase 3
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation Start of enrollment: 2011 Sep 01
Completed
Phase 3
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 3
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission Start of enrollment: 2012 Feb 21
Active, not recruiting
Phase 3
Intergroup Trial for Children or Adolescents With B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients Start of enrollment: 2012 Jun 01
Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma Start of enrollment: 2013 Feb 12
Completed
Phase 2
Brentuximab Vedotin or Crizotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma Start of enrollment: 2013 Nov 13
Active, not recruiting
Phase 2
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 01
Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma Start of enrollment: 2019 Jul 08
Active, not recruiting
Phase 2
Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia Start of enrollment: 2020 Apr 06
Active, not recruiting
Phase 1, Phase 2
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Use of Cancer-Directed therapy at the end of life among adolescents and young adults.
Cernik, C., Xu, L., Laurent, C., Fisher, L., Cannizzaro, N., Munneke, J., Lakin, J., Schwartz, C., Casperson, M., Altschuler, A., Wiener, L., Kushi, L., Chao, C., Uno,...> ;Journal of the National Cancer Institute. 2024 Feb 20
Development and validation of the COVID-19 Hospitalized Patient Deterioration Index.
Cooper, R. M., Claudia Nau, Rebecca K Butler, Cheng-Wei Huang, Vang Kou Khang, Aiyu Chen, Beth Creekmur, Benjamin Broder, Christopher Subject, Adam L Sharp, Luis M Mor...> ;The American Journal of Managed Care. 2023 Dec 1
Quality of End-of-Life Care Among Adolescents and Young Adults With Cancer.
Jennifer W Mack, Colin Cernik, Hajime Uno, Cecile A Laurent, Lauren Fisher, Lanfang Xu, Julie Munneke, Nancy Cannizzaro, Mallory Casperson, Corey M Schwartz, Joshua R ...> ;Journal of Clinical Oncology. 2024 Feb 20
Influence of Comorbidity Burden, Socioeconomic Status, and Race and Ethnicity on Survival Disparities in Patients With Cancer.
Robert M Cooper, Chun Chao, Amrita Mukherjee, Zimin Zhuang, Reina Haque> ;Cancer Control. 2023 Sep 29
Discussions About Goals of Care and Advance Care Planning Among Adolescents and Young Adults With Cancer Approaching the End of Life.
Jennifer W Mack, Colin Cernik, Hajime Uno, Lanfang Xu, Cecile A Laurent, Lauren Fisher, Nancy Cannizzaro, Julie Munneke, Robert M Cooper, Joshua R Lakin, Corey M Schwa...> ;Journal of Clinical Oncology. 2023 Oct 20
1 citations
Investigating Mortality Disparities Among Insured Patients With Colon Cancer Treated in an Integrated Health care System and Other Private Settings.
Jay Patel, Vikram Attaluri, Motahar Basam, Joan Ryoo, David Wu, Amrita Mukherjee, Joanie Chung, Robert M Cooper, Reina Haque> ;The American Surgeon. 2023 Dec 1
6 citations
Disparities in melanoma-specific mortality by race/ethnicity, socioeconomic status, and health care systems.
Amanda Rosenthal, Shivani Reddy, Robert Cooper, Joanie Chung, Jing Zhang, Reina Haque, Christina Kim> ;Journal of the American Academy of Dermatology. 2023 Mar 1
2 citations
Patient, Family, and Clinician Perspectives on Location of Death for Adolescents and Young Adults With Cancer.
Oreofe O Odejide, Lauren Fisher, Lawrence H Kushi, Chun R Chao, Brenda Vega, Gilda Rodrigues, Isabel Josephs, Katharine E Brock, Susan Buchanan, Mallory Casperson, Rob...> ;JCO Oncology Practice. 2022 Oct 1
Pediatric Acute Lymphoblastic Leukemia With Hypereosinophilia and IDH2 Gene Mutation: A Case Report and Literature Review.
Deborah S Gho, Cooper, R. M., Robert M Cooper> ;Journal of Pediatric Hematology/oncology. 2022 Mar 1
24 citations
Patient, Family, and Clinician Perspectives on End-of-Life Care Quality Domains and Candidate Indicators for Adolescents and Young Adults With Cancer.
Jennifer W. Mack, Lauren B. Fisher, Lawrence H. Kushi, Chun Chao, Brenda Vega, Gilda Rodrigues, Isabel Josephs, Katharine E. Brock, Susan Buchanan, Mallory Casperson, ...> ;JAMA Network Open. 2021 Aug 2
2 citations
Influence of health care systems on mortality in adult patients with cancer.
Robert Cooper, Joanie Chung, Tiffany Hogan, Reina Haque> ;The American Journal of Managed Care. 2021 May 1
5 citations
Patterns of overall mortality by race/ethnicity and socioeconomic status in insured cancer patients in Southern California
Robert Cooper, Joanie Chung, Tiffany Hogan, Reina Haque> ;Cancer Causes & Control. 2021 Mar 30
4 citations
Preventive health service use among survivors of adolescent and young adult cancer.
Hilary C. Tanenbaum, Lanfang Xu, Erin E. Hahn, Julie A. Wolfson, Kim Cannavale, Robert Cooper, Chun Chao> ;Preventive Medicine Reports. 2020 Dec 1
3 citations
Immune-related Adverse Effects Associated with Programmed Death-1 Inhibitor Therapy in the Treatment of Non-Small Cell Lung Cancer: Incidence, Management, and Effect o...
Timothy Chiu, Christopher Yamamoto, Fang Niu, Helen Moon, Thach-Giao Truong, Robert Cooper, Rita Hui> ;The Permanente Journal. 2020 Dec 1
2 citations
Adherence to cardiomyopathy screening guidelines among adolescent and young adult cancer survivors exposed to chest radiation and/or anthracyclines.
Hilary C. Tanenbaum, Julie A. Wolfson, Lanfang Xu, Erin E. Hahn, Kimberly L. Cannavale, Robert Cooper, Chun Chao> ;Journal of Cancer Survivorship. 2021 Oct 1
65 citations
Chronic Comorbidities Among Survivors of Adolescent and Young Adult Cancer.
Chun Chao, Lanfang Xu, Kimberly L. Cannavale, F. Lennie Wong, Po-Yin Samuel Huang, Robert Cooper, Saro H. Armenian> ;Journal of Clinical Oncology. 2020 Jul 16
36 citations
Incidence, Risk Factors, and Mortality Associated With Second Malignant Neoplasms Among Survivors of Adolescent and Young Adult Cancer.
Chun Chao, Lanfang Xu, Kimberly L. Cannavale, F. Lennie Wong, Po-Yin Samuel Huang, Robert Cooper, Saro H. Armenian> ;JAMA Network Open. 2019 Jun 5
37 citations
Sustained response of three pediatric BRAF V600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy.
Stephanie A. Toll, Hung N Tran, Jennifer A. Cotter, Alexander R. Judkins, Benita Tamrazi, Jaclyn A. Biegel, Girish Dhall, Nathan Robison, Kaaren Waters, Palak Patel, R...> ;Oncotarget. 2019 Jan 11
3 citations
Heterozygosity for CMT Type 4 Predicts a Severe Vincristine-induced Polyneuropathy Phenotype: A Case Report and Review of Literature.
Andrew Sy, Jerry Cheng, Robert Cooper, Lisa Mueller> ;Journal of Pediatric Hematology/oncology. 2019 Jan 1
19 citations
Use of recommended posttreatment services for adolescent and young adult survivors of Hodgkin lymphoma
Erin E. Hahn, Yi-Lin Wu, Corrine Munoz-Plaza, Jazmine Garcia Delgadillo, Robert Cooper, Chun Chao> ;Cancer. 2019 May 1
29 citations
A task-based assessment of parental occupational exposure to pesticides and childhood acute lymphoblastic leukemia.
Robert B. Gunier, Alice Kang, S. Katharine Hammond, Kyndaron Reinier, C. Suzanne Lea, Jeffrey S. Chang, Monique Does, Ghislaine Scelo, Janice Kirsch, Vonda Crouse, Rob...> ;Environmental Research. 2017 Jul 1
20 citations
Care in the Final Month of Life among Adolescent and Young Adult Cancer Patients in Kaiser Permanente Southern California.
Jennifer W. Mack, Kimberly L. Cannavale, Olivia Sattayapiwat, Bianca Cheung, Lie H. Chen, Robert Cooper, Chun Chao> ;Journal of Palliative Medicine. 2016 Nov 1
3 citations
Tobacco Smoke and Ras Mutations Among Latino and Non-Latino Children with Acute Lymphoblastic Leukemia.
Maneet Kaur, Adam J. de Smith, Steve Selvin, Luoping Zhang, Marc J. Cunningham, Michelle Kang, Helen M. Hansen, Robert Cooper, Roberta McKean-Cowdin, Joseph L. Wiemels...> ;Archives of Medical Research. 2016 Nov 1
102 citations
Cardiovascular Disease Risk Profiles in Survivors of Adolescent and Young Adult (AYA) Cancer: The Kaiser Permanente AYA Cancer Survivors Study
Chun Chao, Lanfang Xu, Robert Cooper, Somjot Brar, F. Lennie Wong, Saro H. Armenian> ;Journal of Clinical Oncology. 2016 Sep 27
77 citations
End-of-Life Care Intensity Among Adolescent and Young Adult Patients With Cancer in Kaiser Permanente Southern California
Jennifer W. Mack, Lie H. Chen, Kimberley Cannavale, Olivia Sattayapiwat, Robert Cooper, Chun Chao> ;JAMA Oncology. 2015 Aug 1
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Professional Memberships

American Society of Clinical Oncology - ASCO
Member

Hospital Affiliations

Kaiser Permanente Los Angeles Medical CenterLos Angeles, California