RobertAHullMD

PubMed

• Analysis of the variation in the action of L-365,260 at CCKB/gastrin receptors in rat, guinea-pig and mouse isolated gastric tissue assays.
  Roberts, S. P., Harper, E. A., Watt, G. F., Gerskowitch, V. P., Hull, R. A., Shankley, N. P., Black, J. W.> ;Br J Pharmacol. 1996 Aug
• Unexpected relationship between plasma protein binding and the pharmacodynamics of 2-NAP, a CCK1-receptor antagonist.
  Gerskowitch, V. P., Hodge, J., Hull, R. A., Shankley, N. P., Kalindjian, S. B., McEwen, J., Black, J. W.> ;Br J Clin Pharmacol. 2007 May
• Development of peptide 3D structure mimetics: rational design of novel peptoid cholecystokinin receptor antagonists.
  Low, C. M., Black, J. W., Broughton, H. B., Buck, I. M., Davies, J. M., Dunstone, D. J., Hull, R. A., Kalindjian, S. B., McDonald, I. M., Pether, M. J., Shankley, N. P...> ;J Med Chem. 2000 Sep 21
• Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists.
  McDonald, I. M., Austin, C., Buck, I. M., Dunstone, D. J., Gaffen, J., Griffin, E., Harper, E. A., Hull, R. A., Kalindjian, S. B., Linney, I. D., Low, C. M., Patel, D....> ;J Med Chem. 2007 Oct 4
• Optimization of 1,3,4-benzotriazepine-based CCK(2) antagonists to obtain potent, orally active inhibitors of gastrin-mediated gastric acid secretion.
  McDonald, I. M., Black, J. W., Buck, I. M., Dunstone, D. J., Griffin, E. P., Harper, E. A., Hull, R. A., Kalindjian, S. B., Lilley, E. J., Linney, I. D., Pether, M. J....> ;J Med Chem. 2007 Jun 28
• Novel, achiral 1,3,4-benzotriazepine analogues of 1,4-benzodiazepine-based CCK(2) antagonists that display high selectivity over CCK(1) receptors.
  McDonald, I. M., Austin, C., Buck, I. M., Dunstone, D. J., Griffin, E., Harper, E. A., Hull, R. A., Kalindjian, S. B., Linney, I. D., Low, C. M., Pether, M. J., Spence...> ;J Med Chem. 2006 Apr 6
• Optimization of the in vitro and in vivo properties of a novel series of 2,4,5-trisubstituted imidazoles as potent cholecystokinin-2 (CCK2) antagonists.
  Buck, I. M., Black, J. W., Cooke, T., Dunstone, D. J., Gaffen, J. D., Griffin, E. P., Harper, E. A., Hull, R. A., Kalindjian, S. B., Lilley, E. J., Linney, I. D., Low,...> ;J Med Chem. 2005 Nov 3
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