Robert McWilliams MD

Oncology•Rochester, MN

Gastrointestinal Cancer, Hematologic Oncology, Melanoma

Professor of Oncology

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200 1st St SWRochester, MN 55905
Phone+1 507-284-2511

Education & Training

Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Hematology and Medical Oncology, 2001 - 2005
Johns Hopkins UniversityResidency, Internal Medicine, 1997 - 2000
Georgetown University School of MedicineClass of 1997

Certifications & Licensure

SD State Medical License Active through 2027
IA State Medical License 2012 - 2026
ID State Medical License 2012 - 2026
IL State Medical License 2012 - 2026
MT State Medical License 2012 - 2026
NY State Medical License 2012 - 2026
MI State Medical License 2012 - 2025
MN State Medical License 2001 - 2025
ND State Medical License 2012 - 2025
TX State Medical License 2015 - 2025
WI State Medical License 2013 - 2025
KY State Medical License 2012 - 2020
MO State Medical License 2012 - 2020
NH State Medical License 2012 - 2020
MD State Medical License 2000 - 2001
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology
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Clinical Trials

Irinotecan, Fluorouracil, Leucovorin, and Oxaliplatin as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer Start of enrollment: 2004 Mar 01
Completed
Phase 2
Carboplatin and ABI-007 in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery Start of enrollment: 2006 Oct 01
Completed
Phase 2
Irinotecan, Oxaliplatin, and Capecitabine as First-Line Therapy in Treating Patients With Metastatic or Unresectable Locally Advanced Small Bowel Cancer Start of enrollment: 2007 May 01
Completed
Phase 2
Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer Start of enrollment: 2008 Jun 01
Completed
Phase 1
Carboplatin, Paclitaxel, and Bevacizumab With or Without Everolimus in Treating Patients With Metastatic Malignant Melanoma Start of enrollment: 2010 Apr 01
Completed
Phase 2
Safety and Efficacy Study of PRI-724 Plus Gemcitabine in Subjects With Advanced or Metastatic Pancreatic Adenocarcinoma Start of enrollment: 2013 Apr 01
Completed
Phase 1
Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Metastatic Melanoma of the Eye That Cannot Be Removed by Surgery Start of enrollment: 2013 Jul 31
Completed
Phase 2
Safety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer Setting Start of enrollment: 2014 Feb 05
Completed
Phase 2
Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations Start of enrollment: 2016 Jan 01
Completed
Early Phase 1
Pembrolizumab in Treating Patients With Small Bowel Adenocarcinoma That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery Start of enrollment: 2017 Mar 24
ACTIVE_NOT_RECRUITING
PHASE2
Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic Cancer Start of enrollment: 2020 Dec 28
ACTIVE_NOT_RECRUITING
PHASE2
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Publications & Presentations

PubMed

Neoadjuvant cobimetinib and atezolizumab with or without vemurafenib for stage III melanoma: outcomes and the impact of the microbiome from the NeoACTIVATE trial.
Matthew S Block, Garth D Nelson, Jun Chen, Stephen Johnson, Lu Yang
Journal for Immunotherapy of Cancer. 2025-04-15
ASO Visual Abstract: Molecular KRAS ctDNA Predicts Metastases and Survival in Pancreatic Cancer-A Prospective Cohort Study.
Jennifer L Leiting, Roberto Alva-Ruiz, Jennifer A Yonkus, Amro M Abdelrahman, Isaac Lynch
Annals of Surgical Oncology. 2025-04-10
Fatty acid synthase (FASN) inhibition cooperates with BH3 mimetic drugs to overcome resistance to mitochondrial apoptosis in pancreatic cancer.
Travis Vander Steen, Ingrid Espinoza, Cristina Duran, Guillem Casadevall, Eila Serrano-Hervás
Neoplasia. 2025-04-01

Journal Articles

Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer
Pashtoon M Kasi, Robert R McWilliams, JAMA
Female Chromosome X Mosaicism Is Age-Related and Preferentially Affects the Inactivated X Chromosome
Chu Chen, J Michael Gaziano, Robert C Kurtz, Anthony M Magliocco, Amy Hutchinson, Robert R McWilliams, Nature

Press Mentions

Palliative Care for Cancer PatientsNovember 22nd, 2024
People with Pancreatic Cancer Are Living Longer, Thanks to Improved ApproachesNovember 30th, 2022
The Topic of CancerJuly 1st, 2022
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Professional Memberships

External Links

Mayo Sitehttp://www.mayo.edu/research/faculty/mcwilliams-robert-r-m-d/bio-00027338