Robert John Mentz MD

Heart Failure & Transplantation

Duke University

40 Duke Medicine CirDurham, NC 27710
Phone+1 919-684-8111
Fax+1 919-620-4921

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Summary

Dr. Robert Mentz is an Associate Professor of Medicine and Chief of the Heart Failure Section at Duke University. He is the Editor-in-Chief of the Journal of Cardiac Failure – the official journal of the HFSA. He completed Internal Medicine training at Brigham and Women’s Hospital and Cardiology Fellowship at Duke University Hospital and the Duke Clinical Research Institute (DCRI). Robert spends his clinical time at Duke University Hospital assisting with the care of patients with heart failure, cardiac transplants and ventricular assist devices. He is an NIH and industry funded clinical trialist involved in ongoing trials designed to inform the care of cardiac patients. He has more than 350 peer-reviewed publications. He is an established mentor for medical students, residents and cardiology fellows and was the recipient of the 2021 Clinical Research Mentoring Award from the Duke School of Medicine and the 2017 W. Proctor Harvey Award from the ACC.

Education & Training

Duke University HospitalFellowship, Cardiovascular Disease, 2010 - 2014
Mass General Brigham/Brigham and Women's HospitalResidency, Internal Medicine, 2007 - 2010
Emory University School of MedicineClass of 2007

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Certifications & Licensure

NC State Medical License 2010 - 2027
MA State Medical License 2009 - 2012
American Board of Internal Medicine Advanced Heart Failure and Transplant Cardiology
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

Clinical Research Mentoring Award Duke School of Medicine, 2021
W. Proctor Harvey Award American College of Cardiology, 2017
CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2015-2017

Clinical Trials

TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure Start of enrollment: 2018 Jul 11
COMPLETED
PHASE3
TRANSFORM-HF Ancillary Mechanistic Study Start of enrollment: 2020 Dec 10
COMPLETED
Changes in NT-proBNP, Safety, and Tolerability in HFpEF Patients With a WHF Event (HFpEF Decompensation) Who Have Been Stabilized and Initiated at the Time of or Within 30 Days Post-decompensation (PARAGLIDE-HF) Start of enrollment: 2019 Jun 29
COMPLETED
PHASE3

Publications & Presentations

PubMed

Comparative effectiveness of torsemide vs furosemide in the management of heart failure patients: Win-ratio reanalysis of the TRANSFORM-HF trial.
Guangyu Tong, Yukang Zeng, Stephen J Greene, Kevin J Anstrom, Jeffrey Testani
American Heart Journal. 2026-11-01
Serial assessment of NT-proBNP and high-sensitivity cardiac troponin with glucagon-like peptide-1 receptor agonist therapy in type 2 diabetes: Insights from EXSCEL.
Veraprapas Kittipibul, Maggie Nguyen, Paul Welsh, John B Buse, Harald Sourij
American Heart Journal. 2026-09-01
A validated, modifiable proteomic score from the EXSCEL trial predicts cardiovascular events in diabetes.
Kristin M Corey, Maggie Nguyen, Michael Y Mi, Megan E Ramaker, Ilya Zhbannikov
JCI Insight. 2026-08-24

Journal Articles

Performance of the Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Body Mass Index
Rohan Khera, Vijay Nambi, Stephen L Seliger, Monika M Safford, Robert J Mentz, Donald M Lloyd-Jones, Ian J Neeland, JAMA Network Open
Cost-Effectiveness of Contemporary Statin Use Guidelines with or Without Coronary Artery Calcium Assessment in African American Individuals
Robert J Mentz, Venkatesh L Murthy, JAMA Cardiology
State-of-the-Art Paper Antihyperglycemic Therapies to Treat Patients with Heart Failure and Diabetes Mellitus
Robert J Mentz, Javed Butler, ScienceDirect

Lectures

Hospitalization for Heart Failure: A Bad Omen or an Opportunity?
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
Acute Heart Failure: What Do We Know? Where Can We go?
2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
Young Investigator Awards: Clinical Investigations
2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019

Authored Content

Cost-Effectiveness of Contemporary Statin Use Guidelines with or Without Coronary Artery Calcium Assessment in African American IndividualsMay 2020
Cost-Effectiveness of Contemporary Statin Use Guidelines with or Without Coronary Artery Calcium Assessment in African American IndividualsMay 2020
Cost-Effectiveness of Contemporary Statin Use Guidelines with or Without Coronary Artery Calcium Assessment in African American IndividualsMay 2020

Press Mentions

A Common Word May Be Giving Heart Patients the Wrong IdeaDecember 10th, 2025
Are Eggs on Your Plate Damaging Your Heart Health? Study Claims Higher Consumption of Eggs May Lead to Early Death; Here’s What You Need to KnowOctober 12th, 2025
Shunt System Still Improving HF Symptoms at 2 YearsFebruary 13th, 2025

Grant Support

Research Triangle Center of Excellence in Regulatory Science and InnovationUNIV OF NORTH CAROLINA CHAPEL HILL2023–2026
Research Triangle Center of Excellence in Regulatory Science and InnovationUNIV OF NORTH CAROLINA CHAPEL HILL2023–2026
Research Triangle Center of Excellence in Regulatory Science and InnovationUNIV OF NORTH CAROLINA CHAPEL HILL2023–2026
Research Triangle Center of Excellence in Regulatory Science and InnovationUNIV OF NORTH CAROLINA CHAPEL HILL2023–2026
TRANSFORM-HFYalePresent