RomSamuelLeidnerMD

PubMed

• NK-92MI Cells Engineered with Anti-claudin-6 Chimeric Antigen Receptors in Immunotherapy for Ovarian Cancer.
  Junping Li, Hong Hu, Hui Lian, Shuo Yang, Manting Liu, Jinping He, Bihui Cao, Dongni Chen, Yuling Hu, Chen Zhi, Yan Shen, Xiaodie Ye, Bingjia He, Ming Zhao, Weijun Fan...> ;International Journal of Biological Sciences. 2024 Jan 1
• FcγRIIB Is an Immune Checkpoint Limiting the Activity of Treg-Targeting Antibodies in the Tumor Microenvironment.
  Knorr, D., Blanchard, L., Leidner, R., Jensen, S., Meng, R., Jones, A., Ballesteros-Merino, C., Bell, R., Baez, M., Marino, A., Sprott, D., Bifulco, C., Piening, B., D...> ;Cancer Immunology Research. 2024 Mar 4
• 1 citations
  First-in-human phase I/Ib study of NIZ985, a recombinant heterodimer of IL-15 and IL-15Rα, as a single agent and in combination with spartalizumab in patients with adv...
  Rom Leidner, Kevin Conlon, Douglas G McNeel, Andrea Wang-Gillam, Sumati Gupta, Robert Wesolowski, Monica Chaudhari, Nadia Hassounah, Jong Bong Lee, Lang Ho Lee, Jessic...> ;Journal for Immunotherapy of Cancer. 2023 Oct 1
• 2 citations
  Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 1st-3rd, 2022-Naples, Italy).
  Paolo A Ascierto, Sanjiv S Agarwala, Allison Betof Warner, Marc S Ernstoff, Bernard A Fox, Thomas F Gajewski, Jérôme Galon, Claus Garbe, Brian R Gastman, Jeffrey E Ger...> ;Journal of Translational Medicine. 2023 Jul 28
• 2 citations
  Cancer's Dark Matter: Lighting the Abyss Unveils Universe of New Therapies.
  Bernard A Fox, Walter J Urba, Shawn M Jensen, David B Page, Brendan D Curti, Rachel E Sanborn, Rom S Leidner> ;Clinical Cancer Research. 2023 Jun 13
• 3 citations
  Safety of Nivolumab Added to Chemoradiation Therapy Platforms for Intermediate and High-Risk Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: RTOG Founda...
  Maura L Gillison, Robert L Ferris, Jonathan Harris, A Dimitrios Colevas, Loren K Mell, Christina Kong, Richard C Jordan, Kevin L Moore, Minh-Tam Truong, Claudia Kirsch...> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Mar 15
• 5 citations
  Chemoradiation therapy alters the PD-L1 score in locoregional recurrent squamous cell carcinomas of the head and neck.
  Brian J Park, Austin K Mattox, Daniel Clayburgh, Mihir Patel, R Bryan Bell, Bevan Yueh, Rom Leidner, Hong Xiao, Marcus Couey, Shiting Li, Tingting Qin, Maureen A Sarto...> ;Oral Oncology. 2022 Dec 1
• 12 citations
  Mogamulizumab in Combination with Nivolumab in a Phase I/II Study of Patients with Locally Advanced or Metastatic Solid Tumors.
  David S. Hong, Olivier Rixe, Vi K. Chiu, Patrick M. Forde, Tomislav Dragovich, Yanyan Lou, Asha Nayak-Kapoor, Rom Leidner, James N. Atkins, Agron Collaku, Floyd Fox, M...> ;Clinical Cancer Research. 2021 Nov 9
• 22 citations
  Phase I study of single agent NIZ985, a recombinant heterodimeric IL-15 agonist, in adult patients with metastatic or unresectable solid tumors
  Kevin C. Conlon, Dionysios C. Watson, Thomas A. Waldmann, Antonio Valentin, Cristina Bergamaschi, Barbara K. Felber, Cody J. Peer, William D. Figg, E. Lake Potter, Mar...> ;Journal for Immunotherapy of Cancer. 2021 Nov 1
• 28 citations
  Immune-related adverse events are associated with improved response, progression-free survival, and overall survival for patients with head and neck cancer receiving i...
  Corey C. Foster, Marcus Couey, Sara Kochanny, Arun Khattri, Rajesh Acharya, Yi-Hung Carol Tan, Ryan J. Brisson, Rom Leidner, Tanguy Y. Seiwert> ;Cancer. 2021 Sep 21
• 4 citations
  A platform for locoregional T-cell immunotherapy to control HNSCC recurrence following tumor resection
  Shay Sharon, Jason R. Baird, Shelly Bambina, Gwen Kramer, Tiffany C. Blair, Shawn M. Jensen, Rom Leidner, R. Bryan Bell, Nardy Casap, Marka R. Crittenden, Michael J. G...> ;Oncotarget. 2021 Jun 22
• 75 citations
  Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial
  Robert L. Ferris, William C. Spanos, Rom Leidner, Anthony Gonçalves, Uwe M Martens, Chrisann Kyi, William H. Sharfman, Christine H. Chung, Lot A. Devriese, Hélène Gaut...> ;Journal for Immunotherapy of Cancer. 2021 Jun 1
• 63 citations
  Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamo...
  Rom Leidner, Marka R. Crittenden, Kristina H. Young, Hong Xiao, Yaping Wu, Marcus Couey, Ashish A. Patel, Allen C. Cheng, Amber L. Watters, Carlo Bifulco, George Morri...> ;Journal for Immunotherapy of Cancer. 2021 May 1
• 36 citations
  Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor.
  Brendan D. Curti, Yoshinobu Koguchi, Rom Leidner, Annah S Rolig, Elizabeth Sturgill, Zhaoyu Sun, Yaping Wu, Venkatesh Rajamanickam, Brady Bernard, Ian Hilgart-Martiszu...> ;Journal for Immunotherapy of Cancer. 2021 Apr 1
• 84 citations
  Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells.
  Rebekka Duhen, Carmen Ballesteros-Merino, Alexandra K. Frye, Eric Tran, Venkatesh Rajamanickam, Shu-Ching Chang, Yoshinobu Koguchi, Carlo Bifulco, Brady Bernard, Rom L...> ;Nature Communications. 2021 Feb 16
• 5 citations
  Explant Modeling of the Immune Environment of Head and Neck Cancer.
  Shay Sharon, Thomas Duhen, Shelly Bambina, Jason R. Baird, Rom Leidner, Bryan Bell, Nardy Casap, Marka R. Crittenden, Swetha Vasudevan, Maria R Jubran, Nataly Kravchen...> ;Frontiers in Oncology. 2021 Jun 17
• 28 citations
  Safety and clinical activity of MEDI0562, a humanized OX40 agonist monoclonal antibody, in adult patients with advanced solid tumors
  Bonnie S. Glisson, Rom Leidner, Robert L. Ferris, John D. Powderly, Naiyer A. Rizvi, Bhumsuk Keam, Reva Schneider, Sanjay Goel, James Ohr, Jennifer Burton, Yanan Zheng...> ;Clinical Cancer Research. 2020 Oct 15
• 9 citations
  Transoral robotic surgery and neck dissection for HPV-positive oropharyngeal carcinoma: Importance of nodal count in survival
  Chi T. Viet, Eric J. Dierks, Allen C. Cheng, Ashish A. Patel, Shu-Ching Chang, Marcus Couey, Amber L. Watters, Thien Hoang, Hong D. Xiao, Marka R. Crittenden, Rom Leid...> ;Oral Oncology. 2020 Oct 1
• 41 citations
  First-In-Human Study of Cemiplimab Alone or In Combination with Radiotherapy and/or Low Dose Cyclophosphamide in Patients with Advanced Malignancies.
  Kyriakos P. Papadopoulos, Melissa Lynne Johnson, Albert C. Lockhart, Kathleen N. Moore, Gerald Steven Falchook, Silvia C. Formenti, Aung Naing, Richard D. Carvajal, Le...> ;Clinical Cancer Research. 2020 Mar 1
• 75 citations
  Safety and Efficacy of Durvalumab and Tremelimumab Alone or in Combination in Patients with Advanced Gastric and Gastroesophageal Junction Adenocarcinoma.
  Ronan J. Kelly, Jeeyun Lee, Yung-Jue Bang, Khaldoun Almhanna, Mariela Blum-Murphy, Daniel V.T. Catenacci, Hyun Cheol Chung, Zev A. Wainberg, Michael K. Gibson, Keun Wo...> ;Clinical Cancer Research. 2019 Nov 1
• 360 citations
  The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC)
  Ezra E.W. Cohen, R. Bryan Bell, Carlo Bifulco, Barbara Burtness, Maura L. Gillison, Kevin J. Harrington, Quynh-Thu Le, Nancy Y. Lee, Rom Leidner, Rebecca L. Lewis, Lis...> ;Journal for Immunotherapy of Cancer. 2019 Jul 15
• The role of antimicrobial prophylaxis in patients with head and neck cancer undergoing chemoradiation.
  Alina T Jaeger, James E Connelly, Ruyun Jin, Samuel N Jacobson, Rom Leidner> ;Journal of Oncology Pharmacy Practice. 2020 Apr 1
• 120 citations
  Delayed immune-related events (DIRE) after discontinuation of immunotherapy: diagnostic hazard of autoimmunity at a distance
  Marcus Couey, R. Bryan Bell, Ashish A. Patel, Marka R. Crittenden, Brendan D. Curti, Walter J. Urba, Rom Leidner> ;Journal for Immunotherapy of Cancer. 2019 Jul 3
• 21 citations
  Immunotherapy for Head and Neck Cancer.
  Felix Sim, Rom Leidner, R.B. Bell> ;Hematology/oncology Clinics of North America. 2019 Apr 1
• 23 citations
  Immunotherapy for Head and Neck Cancer
  Felix Sim, Rom Leidner, R.B. Bell> ;Oral and Maxillofacial Surgery Clinics of North America. 2019 Feb 1
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Lectures

• A phase 2, multicenter study to evaluate the efficacy and safety of autologous tumor infiltrating lymphocytes (LN-145) for the treatment of patients with recurrent and... 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/2/2018