RonaYaegerMD

PubMed

• Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer.
  Rona Yaeger, Nataliya V Uboha, Meredith S Pelster, Tanios S Bekaii-Saab, Minal Barve, Joel Saltzman, Joshua K Sabari, Julio A Peguero, Andrew Scott Paulson, Pasi A Jän...> ;Cancer Discovery. 2024 Apr 8
• Molecular and Clinical Determinants of Acquired Resistance and Treatment Duration for Targeted Therapies in Colorectal Cancer.
  Emily Harrold, Fergus Keane, Henry Walch, Joanne F Chou, Jenna Sinopoli, Silvia Palladino, Duaa H Al-Rawi, Kalyani Chadalavada, Paolo Manca, Sree Chalasani, Jessica Ya...> ;Clinical Cancer Research. 2024 Mar 19
• Alliance for clinical trials in Oncology (Alliance) trial A022101/NRG-GI009: a pragmatic randomized phase III trial evaluating total ablative therapy for patients with...
  Kathryn E Hitchcock, Eric D Miller, Qian Shi, Jesse G Dixon, Sepideh Gholami, Sarah B White, Christina Wu, Christopher C Goulet, Manju George, Kyung-Wook Jee, Chadwick...> ;BMC Cancer. 2024 Feb 13
• 1 citations
  Alveolar Differentiation Drives Resistance to KRAS Inhibition in Lung Adenocarcinoma.
  Li, Z., Zhuang, X., Pan, C., Yan, Y., Thummalapalli, R., Hallin, J., Torborg, S., Singhal, A., Chang, J., Manchado, E., Dow, L., Yaeger, R., Christensen, J., Lowe, S.,...> ;Cancer Discovery. 2024 Feb 8
• Negative Hyperselection of Patients with HER2+ and RAS Wild-Type Metastatic Colorectal Cancer Receiving Dual HER2 Blockade: the PRESSING-HER2 Study.
  Randon, G., Nakamura, Y., Yaeger, R., Lonardi, S., Cremolini, C., Elez, E., Nichetti, F., Ghelardi, F., Nasca, V., Bergamo, F., Conca, V., Ros, J., Bando, H., Maddalen...> ;Clinical Cancer Research. 2024 Jan 17
• 1 citations
  Sotorasib with panitumumab in chemotherapy-refractory KRAS-mutated colorectal cancer: a phase 1b trial.
  Kuboki, Y., Fakih, M., Strickler, J., Yaeger, R., Masuishi, T., Kim, E., Bestvina, C., Kopetz, S., Falchook, G., Langer, C., Krauss, J., Puri, S., Cardona, P., Chan, E...> ;Nature Medicine. 2024 Jan 1
• Alliance for Clinical Trials in Oncology (Alliance) trial A022101/NRG-GI009: A pragmatic randomized phase III trial evaluating total ablative therapy for patients with...
  Hitchcock, K., Miller, E., Shi, Q., Dixon, J., Gholami, S., White, S., Wu, C., Goulet, C., George, M., Jee, K., Wright, C., Yaeger, R., Shergill, A., Hong, T., George,...> ;Research Square. 2023 Dec 23
• Combination Therapy and Appropriate Dosing to Target KRAS in Colorectal Cancer.
  Yaeger, R.> ;The New England Journal of Medicine. 2023 Dec 7
• Effects of KRAS Genetic Interactions on Outcomes in Cancers of the Lung, Pancreas, and Colorectum.
  Isabella N Grabski, John V Heymach, Kenneth L Kehl, Scott Kopetz, Ken S Lau, Gregory J Riely, Deborah Schrag, Rona Yaeger, Rafael A Irizarry, Kevin M Haigis> ;Cancer Epidemiology, Biomarkers & Prevention. 2024 Jan 9
• 1 citations
  Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer.
  Yang Feng, Qingchen Yuan, Rachel C Newsome, Troy Robinson, Robert L Bowman, Ashley N Zuniga, Kendra N Hall, Cassandra M Bernsten, Daniil E Shabashvili, Kathryn I Krajc...> ;The Journal of Experimental Medicine. 2023 Nov 6
• 2 citations
  Neoplasia risk in patients with Lynch syndrome treated with immune checkpoint blockade.
  Emily C Harrold, Michael B Foote, Benoit Rousseau, Henry Walch, Yelena Kemel, Allison L Richards, Fergus Keane, Andrea Cercek, Rona Yaeger, Dana Rathkopf, Neil H Segal...> ;Nature Medicine. 2023 Oct 1
• 1 citations
  KRASinhibition in pancreatic cancer: Fas expression facilitates immune clearance.
  Celine Yeh, Wungki Park, Rona Yaeger> ;Developmental Cell. 2023 Sep 11
• 2 citations
  Combined RAF and MEK Inhibition to Treat Activated Non-V600 BRAF-Altered Advanced Cancers.
  Naryan Rustgi, Ann Maria, Nicolas Toumbacaris, HuiYong Zhao, Katherine Kargus, Morgan Bryant, Alexandra Waksmundzki, Ilinca Aricescu, Robert A Lefkowitz, Bob T Li, Joa...> ;The Oncologist. 2024 Jan 5
• 1 citations
  Phase Ib/II Study of the Efficacy and Safety of Binimetinib (MEK162) Plus Panitumumab for Mutant or Wild-Type RAS Metastatic Colorectal Cancer.
  Eric Van Cutsem, Rona Yaeger, Jean-Pierre Delord, Josep Tabernero, Lillian L Siu, Michel Ducreux, Salvatore Siena, Elena Elez, Stefan Kasper, Thomas Zander, Neeltje St...> ;The Oncologist. 2023 Dec 11
• Prevalence and Clinical Implications of Mismatch Repair-Proficient Colorectal Cancer in Patients With Lynch Syndrome.
  Megha Ranganathan, Rosalba E Sacca, Magan Trottier, Anna Maio, Yelena Kemel, Erin Salo-Mullen, Amanda Catchings, Sarah Kane, Chiyun Wang, Vignesh Ravichandran, Ryan Pt...> ;JCO Precision Oncology. 2023 May 1
• 19 citations
  Adagrasib in Advanced Solid Tumors Harboring aMutation.
  Tanios S Bekaii-Saab, Rona Yaeger, Alexander I Spira, Meredith S Pelster, Joshua K Sabari, Navid Hafez, Minal Barve, Karen Velastegui, Xiaohong Yan, Aditya Shetty, Hir...> ;Journal of Clinical Oncology. 2023 Sep 1
• 18 citations
  ANCHOR CRC: Results From a Single-Arm, Phase II Study of Encorafenib Plus Binimetinib and Cetuximab in Previously Untreated-Mutant Metastatic Colorectal Cancer.
  Eric Van Cutsem, Julien Taieb, Rona Yaeger, Takayuki Yoshino, Axel Grothey, Evaristo Maiello, Elena Elez, Jeroen Dekervel, Paul Ross, Ana Ruiz-Casado, Janet Graham, Ta...> ;Journal of Clinical Oncology. 2023 May 10
• 1 citations
  Clinical Importance of Clonal Hematopoiesis in Metastatic Gastrointestinal Tract Cancers.
  Bill H Diplas, Ryan Ptashkin, Joanne F Chou, Shalom Sabwa, Michael B Foote, Benoit Rousseau, Guillem Argilés, James Robert White, Caitlin M Stewart, Kelly Bolton, Sree...> ;JAMA Network Open. 2023 Feb 1
• 4 citations
  KRAS inhibition in metastatic colorectal cancer: An update.
  Maliha Nusrat, Rona Yaeger> ;Current Opinion in Pharmacology. 2023 Feb 1
• 5 citations
  Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers.
  Walid K Chatila, Henry Walch, Jaclyn F Hechtman, Sydney M Moyer, Valeria Sgambati, David M Faleck, Amitabh Srivastava, Laura Tang, Jamal Benhamida, Dorina Ismailgeci, ...> ;Nature Communications. 2023 Jan 7
• 81 citations
  Adagrasib with or without Cetuximab in Colorectal Cancer with MutatedG12C.
  Rona Yaeger, Jared Weiss, Meredith S Pelster, Alexander I Spira, Minal Barve, Sai-Hong I Ou, Ticiana A Leal, Tanios S Bekaii-Saab, Cloud P Paweletz, Grace A Heavey, Ja...> ;The New England Journal of Medicine. 2023 Jan 5
• 8 citations
  Molecular Classification of Appendiceal Adenocarcinoma.
  Michael B Foote, Henry Walch, Walid Chatila, Efsevia Vakiani, Chris Chandler, Felix Steinruecke, Garrett M Nash, Zsofia Stadler, Sebastian Chung, Rona Yaeger, Maria Ig...> ;Journal of Clinical Oncology. 2023 Mar 10
• 12 citations
  Molecular Characterization of Acquired Resistance to KRASG12C-EGFR Inhibition in Colorectal Cancer.
  Rona Yaeger, Riccardo Mezzadra, Jenna Sinopoli, Yu Bian, Michelangelo Marasco, Esther Kaplun, Yijun Gao, HuiYong Zhao, Arnaud Da Cruz Paula, Yingjie Zhu, Almudena Chav...> ;Cancer Discovery. 2023 Jan 9
• 1 citations
  Natural Language Processing of Computed Tomography Reports to Label Metastatic Phenotypes With Prognostic Significance in Patients With Colorectal Cancer.
  Pamela Causa Andrieu, Jennifer S Golia Pernicka, Rona Yaeger, Kaelan Lupton, Karen Batch, Farhana Zulkernine, Amber L Simpson, Michio Taya, Lior Gazit, Huy Nguyen, Kev...> ;JCO Clinical Cancer Informatics. 2022 Sep 1
• 205 citations
  Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy.
  Julio Garcia-Aguilar, Sujata Patil, Marc J Gollub, Jin K Kim, Jonathan B Yuval, Hannah M Thompson, Floris S Verheij, Dana M Omer, Meghan Lee, Richard F Dunne, Jorge Ma...> ;Journal of Clinical Oncology. 2022 Aug 10
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Lectures

• Practical Application of Tumor Mutation Analysis and Profiling 
  ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/25/2020