RuthA.KarronMD

Pediatric Infectious Disease • Baltimore, MD

Joint of Pediatrics, Johns Hopkins University School of Medicine

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Office
1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287
Phone+1 410-614-3917
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Education & Training

Johns Hopkins UniversityFellowship, Infectious Disease, 1987 - 1988
National Capital ConsortiumResidency, Pediatrics, 1985 - 1987
Children's National Medical CenterResidency, Pediatrics, 1982 - 1985
New York University School of MedicineClass of 1982

Certifications & Licensure

MD State Medical License 1989 - 2024
American Board of Pediatrics Pediatrics

Clinical Trials

Safety of and Immune Response to a Bird Flu Virus Vaccine (H9N2) in Healthy Adults (Study A) Start of enrollment: 2005 Jun 01
Completed
Phase 1
Safety of and Immune Response to a Human Parainfluenza Virus Vaccine (rHPIV3cp45) in Healthy Infants Start of enrollment: 2006 Jun 01
Completed
Phase 1
Safety of and Immune Response to a Bird Flu Virus Vaccine (H5N1) in Healthy Adults Start of enrollment: 2006 Jun 01
Completed
Phase 1
Safety of and Immune Response to a Cow/Human Parainfluenza Virus Vaccine (rB/HPIV3) in Healthy Infants, Children, and Adults Start of enrollment: 2007 Mar 01
Completed
Phase 1
Safety of and Immune Response to a Bird Flu Virus Vaccine (H9N2) in Healthy Adults (Study B) Start of enrollment: 2006 Oct 01
Completed
Phase 1
Single Group Study of the Safety of and Immune Response to a Bird Flu Virus Vaccine (H5N1) in Healthy Adults Start of enrollment: 2007 Jun 01
Completed
Phase 1
Safety of and Immune Response to Recombinant Live-Attenuated Parainfluenza Type 1 Virus Vaccine Start of enrollment: 2008 Mar 01
Completed
Phase 1
Safety of and Immune Response to Recombinant Live Attenuated Parainfluenza Type 3 Virus Vaccine in Healthy Infants and Children Start of enrollment: 2009 Nov 01
Completed
Phase 1
Safety Study of a Human Metapneumovirus Challenge Virus in Healthy Adults Start of enrollment: 2010 Jun 01
Completed
Phase 1
Safety of a Live Attenuated Human Parainfluenza Virus Type 2 (HPIV2) Vaccine for Adults, Children, and Infants Start of enrollment: 2010 Jun 01
Completed
Phase 1
Evaluation of the Safety and Immunogenicity of a Live Attenuated Human Metapneumovirus Vaccine Start of enrollment: 2011 Jan 01
Completed
Phase 1
Evaluating the Safety and Immune Response to a Respiratory Syncytial Virus (RSV) Vaccine in Adults, RSV-Seropositive Children, and RSV-Seronegative Infants and Children Start of enrollment: 2011 Aug 01
Completed
Phase 1
Evaluating the Safety and Immune Response to a Single Dose of a Respiratory Syncytial Virus (RSV) Vaccine in RSV-Seronegative Infants and Children Start of enrollment: 2013 Oct 01
Completed
Phase 1
Evaluating the Safety and Immune Response to a Single Dose of a Respiratory Syncytial Virus (RSV) Vaccine in Infants and Children Start of enrollment: 2013 Jun 01
Active, not recruiting
Phase 1
Safety and Immune Response to a Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccine in RSV-Seronegative Infants and Children Start of enrollment: 2014 Sep 01
Completed
Phase 1
Infectivity, Safety and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine (RSV LID cp ΔM2-2) in RSV-Seronegative Infants and Children 6 to 24 Months of Age Start of enrollment: 2016 Sep 01
Terminated
Phase 1
Evaluating the Infectivity, Safety, and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine in RSV-Seronegative Infants and Children 6 to 24 Months of Age Start of enrollment: 2016 Aug 01
Completed
Phase 1
Infectivity, Safety and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine (D46/NS2/N/ΔM2-2-HindIII) in RSV-Seronegative Infants and Children 6 to 24 Months of Age Start of enrollment: 2017 Apr 01
Completed
Phase 1
Evaluating the Infectivity, Safety, and Immunogenicity of a Respiratory Syncytial Virus Vaccine (RSV 6120/∆NS2/1030s) in RSV-Seropositive Children and RSV-Seronegative Infants and Children Start of enrollment: 2017 Oct 13
Completed
Phase 1
Evaluating the Infectivity, Safety, and Immunogenicity of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L or RSV 276 in RSV-Seronegative Infants and Children 6 to 24 Months of Age Start of enrollment: 2017 Oct 04
Active, not recruiting
Phase 1
Evaluating the Infectivity, Safety and Immunogenicity of Respiratory Syncytial Virus Vaccines, RSV 6120/∆NS1 and RSV 6120/F1/G2/∆NS1, in RSV-Seropositive Children and RSV-Seronegative Infants and Children Start of enrollment: 2018 Jun 25
Recruiting
Phase 1
Safety and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L, RSV 6120/ΔNS2/1030s, RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Children 6 to 24 Months of Age Start of enrollment: 2019 May 16
Active, not recruiting
Phase 1, Phase 2
Evaluating the Infectivity, Safety and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine, LID/ΔM2-2/1030s, in RSV-Seronegative Infants and Children 6 to 24 Months of Age Start of enrollment: 2022 Feb 23
Active, not recruiting
Phase 1
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Publications & Presentations

PubMed

key antecedents and questions for acceptance of a future maternal GBS vaccine: Perspectives of pregnant women, lactating women, and community members in Kenya.
Limaye, R., Singh, P., Fesshaye, B., Lee, C., Schue, J., Karron, R.> ;Human Vaccines & Immunotherapeutics. 2024 Dec 31
Lessons learned from COVID-19 vaccine acceptance among pregnant and lactating women from two districts in Kenya to inform demand generation efforts for future maternal...
Rupali J Limaye, Prachi Singh, Berhaun Fesshaye, Ruth A Karron> ;BMC Pregnancy and Childbirth. 2024 Mar 27
Characterizing Attitudes Toward Maternal RSV Vaccines Among Pregnant and Lactating Persons in Kenya: Key Considerations for Demand Generation Efforts for Vaccine Accep...
Rupali J Limaye, Molly Sauer, Rosemary Njogu, Prachi Singh, Berhaun Fesshaye, Karron, R.> ;Journal of the Pediatric Infectious Diseases Society. 2023 Dec 16
COVID-19 vaccine eligibility of pregnant and lactating women in Bangladesh: Gap between policy and policy interpretation among policymakers and healthcare workers.
Rupali J Limaye, Berhaun Fesshaye, Prachi Singh, Eleonor Zavala, Shirina Akter, Towfida Jahan Siddiqua, Hafizur Rahman, Hasmot Ali, Ruth Karron> ;Vaccine. 2023 Dec 1
1 citations
The full value of immunisation against respiratory syncytial virus for infants younger than 1 year: effects beyond prevention of acute respiratory illness.
Daniel R Feikin, Ruth A Karron, Samir K Saha, Erin Sparrow, Padmini Srikantiah, Daniel M Weinberger, Heather J Zar> ;The Lancet. Infectious Diseases. 2023 Nov 21
Sources of COVID-19 Vaccine Promotion for Pregnant and Lactating Women in Bangladesh.
Berhaun Fesshaye, Sydney A Wade, Clarice Lee, Prachi Singh, Eleonor Zavala, Hasmot Ali, Hafizur Rahman, Towfida Jahan Siddiqua, Shirina Atker, Ruth A Karron, Rupali J ...> ;Vaccines. 2023 Aug 20
1 citations
RSV awareness, risk perception, causes, and terms: Perspectives of pregnant and lactating women in Kenya to inform demand generation efforts for maternal RSV vaccines.
Rupali J Limaye, Berhaun Fesshaye, Prachi Singh, Ruth A Karron> ;Human Vaccines & Immunotherapeutics. 2023 Aug 1
Effect of infant viral respiratory disease on childhood asthma in a non-industrialized setting.
Jessica Atwell, Martha Chico, Maritza Vaca, Andrea Arévalo-Cortes, Ruth Karron, Philip J Cooper> ;Clinical and Translational Allergy. 2023 Aug 1
3 citations
Evaluation of the Live-Attenuated Intranasal Respiratory Syncytial Virus (RSV) Vaccine RSV/6120/ΔNS2/1030s in RSV-Seronegative Young Children.
Ruth A Karron, Cindy Luongo, Suzanne Woods, Jennifer Oliva, Peter L Collins, Ursula J Buchholz> ;The Journal of Infectious Diseases. 2024 Feb 14
5 citations
RSV Among American Indian and Alaska Native Children: 2019 to 2020.
Jessica E Atwell, Rachel M Hartman, Dennie Parker, Kim Taylor, Laura B Brown, Marqia Sandoval, Nina Ritchie, Christine Desnoyers, Amy Swango Wilson, Melissa Hammes, Ja...> ;Pediatrics. 2023 Aug 1
1 citations
Vaccine Value Profiles.
Birgitte Giersing, Ruth Karron, Marta Tufet-Bayona, Caroline Trotter, Philipp Lambach, Mark Jit> ;Vaccine. 2023 Nov 3
2 citations
Value profile for respiratory syncytial virus vaccines and monoclonal antibodies.
Jessica A Fleming, Ranju Baral, Deborah Higgins, Sadaf Khan, Sonali Kochar, You Li, Justin R Ortiz, Thomas Cherian, Daniel Feikin, Mark Jit, Ruth A Karron, Rupali J Li...> ;Vaccine. 2023 Nov 3
COVID-19 vaccine decision-making among pregnant and lactating women in Bangladesh.
Rupali J Limaye, Prachi Singh, Alicia Paul, Berhaun Fesshaye, Clarice Lee, Eleonor Zavala, Sydney Wade, Hasmot Ali, Hafizur Rahman, Shirina Akter, Ruth Karron, Towfida...> ;Vaccine. 2023 Jun 13
1 citations
Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Antibody Responses After Community Infections in Children and Adults.
Fatimah S Dawood, Alexia Couture, Xueyan Zhang, Melissa S Stockwell, Christina A Porucznik, Joseph B Stanford, Marissa Hetrich, Vic Veguilla, Natalie Thornburg, Christ...> ;Open Forum Infectious Diseases. 2023 May 1
6 citations
RSV Illness in the Young and the Old - The Beginning of the End?
Ruth A Karron> ;The New England Journal of Medicine. 2023 Apr 20
2 citations
Safety, immunogenicity, and effectiveness of COVID-19 vaccines for pregnant persons: A protocol for systematic review and meta analysis.
Agustín Ciapponi, Mabel Berrueta, Jamile Ballivian, Ariel Bardach, Agustina Mazzoni, Steven Anderson, Fernando J Argento, Karin Bok, Daniel Comandé, Erin Goucher, Beat...> ;Medicine. 2023 Mar 3
1 citations
The Pregnancy, Arsenic, and Immune Response (PAIR) Study in rural northern Bangladesh.
Lindsay N Avolio, Tyler J S Smith, Ana Navas-Acien, Kate Kruczynski, Nora Pisanic, Pranay R Randad, Barbara Detrick, Rebecca C Fry, Alexander van Geen, Walter Goessler...> ;Paediatric and Perinatal Epidemiology. 2023 Feb 1
1 citations
Evaluation of a Live-Attenuated Human Parainfluenza Virus Type 2 Vaccine in Adults and Children.
Ruth A Karron, Kristi Herbert, Kimberli Wanionek, Alexander C Schmidt, Anne Schaap-Nutt, Peter L Collins, Ursula J Buchholz> ;Journal of the Pediatric Infectious Diseases Society. 2023 Apr 18
1 citations
Epidemiology of Human Parainfluenza Virus Type 3 and Respiratory Syncytial Virus Infections in the Time of Coronavirus Disease 2019: Findings From a Household Cohort i...
Marissa K Hetrich, Jennifer Oliva, Kimberli Wanionek, Maria Deloria Knoll, Matthew Lamore, Ignacio Esteban, Vic Veguilla, Fatimah S Dawood, Ruth A Karron> ;Clinical Infectious Diseases. 2023 Apr 17
6 citations
A socio-ecological exploration to identify factors influencing the COVID-19 vaccine decision-making process among pregnant and lactating women: Findings from Kenya.
Rupali J Limaye, Alicia Paul, Rachel Gur-Arie, Eleonor Zavala, Clarice Lee, Berhaun Fesshaye, Prachi Singh, Wincate Njagi, Paul Odila, Paul Munyao, Rosemary Njogu, Ste...> ;Vaccine. 2022 Nov 28
3 citations
Lack of clear national policy guidance on COVID-19 vaccines influences behaviors in pregnant and lactating women in Kenya.
Eleonor Zavala, Berhaun Fesshaye, Clarice Lee, Stephen Mutwiwa, Wincate Njagi, Paul Munyao, Rosemary Njogu, Rachel Gur-Arie, Alicia M Paul, Taylor A Holroyd, Prachi Si...> ;Human Vaccines & Immunotherapeutics. 2022 Nov 30
Predictors of Severe Acute Respiratory Syndrome Coronavirus 2 Seropositivity Before Coronavirus Disease 2019 Vaccination Among Children 0-4 Years and Their Household M...
Maria Garcia Quesada, Marissa K Hetrich, Scott Zeger, Jayati Sharma, Yu Bin Na, Vic Veguilla, Ruth A Karron, Fatimah S Dawood, Maria D Knoll> ;Open Forum Infectious Diseases. 2022 Oct 1
3 citations
Conceptualizing the COVID-19 Pandemic: Perspectives of Pregnant and Lactating Women, Male Community Members, and Health Workers in Kenya.
Alicia M Paul, Clarice Lee, Berhaun Fesshaye, Rachel Gur-Arie, Eleonor Zavala, Prachi Singh, Ruth A Karron, Rupali J Limaye> ;International Journal of Environmental Research and Public Health. 2022 Aug 30
3 citations
Impact of Age and Symptom Development on SARS-CoV-2 Transmission in Households With Children-Maryland, New York, and Utah, August 2020-October 2021.
Kelsey M Sumner, Ruth A Karron, Melissa S Stockwell, Fatimah S Dawood, Joseph B Stanford, Alexandra Mellis, Emily Hacker, Priyam Thind, Maria Julia E Castro, John Paul...> ;Open Forum Infectious Diseases. 2022 Aug 1
7 citations
Assessment of Clinical and Virological Characteristics of SARS-CoV-2 Infection Among Children Aged 0 to 4 Years and Their Household Members.
Ruth A Karron, Marissa K Hetrich, Yu Bin Na, Maria Deloria Knoll, Elizabeth Schappell, Jennifer Meece, Erika Hanson, Suxiang Tong, Justin S Lee, Vic Veguilla, Fatimah ...> ;JAMA Network Open. 2022 Aug 1
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Journal Articles

Informing Randomized Clinical Trials of Respiratory Syncytial Virus Vaccination During Pregnancy to Prevent Recurrent Childhood Wheezing: A Sample Size Analysis
Tina V Hartert, Niranjan Bhat, Ruth A Karron, Justin R Ortiz, ScienceDirect

Authored Content

An ‘Indefensible’ Decision: Not Vaccinating Pregnant and Lactating Women in an Ebola OutbreakAugust 2018

Press Mentions

We’ll Soon Have Tools To Protect Infants Against RSV. Can We Put Them To Good Use?May 24th, 2023
FDA Approves World’s First RSV Vaccine for Adults 60 and OlderMay 3rd, 2023
FDA Approves First Vaccine for RSV, a Moment Six Decades in the MakingMay 3rd, 2023
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