Dr. Klempner is on Doximity
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Office
MGH Cancer Center
55 Fruit Street
Boston, MA 02114- Is this information wrong?
Education & Training
- Beth Israel Deaconess Medical CenterFellowship, Hematology and Medical Oncology, 2010 - 2013
- Brigham and Women's HospitalResidency, Internal Medicine, 2007 - 2010
- University of Massachusetts Medical SchoolClass of 2007
- Hamilton CollegeB.A., Magna Cum Laude, 2003
Certifications & Licensure
- MA State Medical License 2010 - 2025
- ME State Medical License 2021 - 2024
- CA State Medical License 2013 - 2020
- American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- Standing Ovation Award Cedars-Sinai Medical Center, 2016
- SuperDoctors Southern CA Rising Star 2016-2017
- Top Physician Communicator UC Irvine, 2015
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Publications & Presentations
PubMed
- 205 citationsReal-Time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations That Might Be Targeted With Existing Drugs or Used as Bi...Aatur D. Singhi, Ben George, Joel R. Greenbowe, Jon Chung, James Suh
Gastroenterology. 2019-06-01 - 107 citationsAdagrasib with or without Cetuximab in Colorectal Cancer with MutatedG12C.Rona Yaeger, Jared Weiss, Meredith S Pelster, Alexander I Spira, Minal Barve
The New England Journal of Medicine. 2023-01-05 - 61 citationsCorrelating programmed death ligand 1 (PD-L1) expression, mismatch repair deficiency, and outcomes across tumor types: implications for immunotherapy.Seung Tae Kim, Samuel J. Klempner, Se Hoon Park, Joon Oh Park, Young Suk Park
Oncotarget. 2017-08-26
Journal Articles
- PD-1 as an emerging target in gastric cancer: current evidenceTran PN, Sarkissian S, Chao J, Klempner SJ, Gastrointestinal Cancer: Targets and Therapy, 1/1/2017
- Moving Molecular Subtypes to the Clinic in Gastric CancerChao J, Lee J, Klempner SJ, Transl Cancer Res, 1/1/2016
- ROS1 (c-ros oncogene 1)Klempner SJ, Ou, SH, Atlas Genet Cytogenet Oncol Haematol, 1/1/2014
Books/Book Chapters
Abstracts/Posters
- Neoadjuvant Chemotherapy Improves Survival In Patients With Clinical T4b Colon Cancer.Dehal A, Graff-Baker AN, Voung B, Fischer T, Klempner SJ, et al, Digestive Disease Week, Chicago, IL, 1/6/2017
- A Phase 1 Study of LY3022855 (A Colony-Stimulating Factor-1 receptor [CSF-1R] inhibitor) in Patients (pts) With Advanced Solid TumorsDowlati A, Rugo HS, et al, ASCO, 1/1/2017
- Comprehensive genomic profiling (CGP) of esophageal and tubular GI tumors identifies differing frequencies of ErbB family member amplifications with therapeutic implic...Bailey M, Ali SM, Schrock AB, Klempner SJ, George B, Lipson D, et al, GI ASCO, 1/1/2017
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Lectures
- DKN-01 in combination with pembrolizumab in patients with advanced gastroesophageal adenocarcinoma (GEA): Tumoral DKK1 expression as a predictor of response and survival.ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/23/2020
- Early Is Better: The Roles of Prevention, Screening, and Early DetectionASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/23/2020
- Help From Within: DNA to Personalized Therapy for Gastric Cancer1/18/2017
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Authored Content
- Immunotherapies as a Targeted Therapy to Accelerate Personalized CareFebruary 2020
- Immunotherapies as a Targeted Therapy to Accelerate Personalized CareFebruary 2020
Press Mentions
- Immunotherapy Is Now the First Choice for Esophageal CancerMay 31st, 2022
- Leap Therapeutics to Present New Data from the DisTinGuish Study of DKN-01 plus Tislelizumab at the ESMO 2021 CongressSeptember 13th, 2021
- Leap Therapeutics to Present at the ESMO 2021 Virtual CongressJuly 26th, 2021
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Professional Memberships
- Member
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- ESMOMember
Hospital Affiliations
- Massachusetts General HospitalBoston, Massachusetts
- Dana-Farber Cancer InstituteBoston, Massachusetts
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