SamuelIMillerMD

Infectious Disease • Seattle, WA

Professor, Medicine, University of Washington School of Medicine

Join to view full profile

Dr. Miller is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Miller's full profile

Already have an account?

Office
University Of Washington Medical Ctr
1959 Ne Pacific St
Seattle, WA 98195
Phone+1 206-598-7600
Is this information wrong?

Education & Training

Massachusetts General Hospital/Brigham and Women's Hospital/Harvard Medical SchoolFellowship, Infectious Disease, 1982 - 1984
Massachusetts General HospitalResidency, Internal Medicine, 1980 - 1983
Baylor College of MedicineClass of 1979, MD

Certifications & Licensure

WA State Medical License 1996 - 2026
CA State Medical License 2021 - 2025
TX State Medical License 1980 - 1988
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Infectious Disease

Awards, Honors, & Recognition

Elected Member The American Society for Clinical Investigation, 1994

Publications & Presentations

PubMed

2 citations
Toxin Glycan Binding: Lectin Keys Unlocking Host and Tissue Specificity
Erik Petersen, Samuel I. Miller> ;Cell Host & Microbe. 2020 Jun 10
22 citations
Structure of an Inner Membrane Protein Required for PhoPQ-Regulated Increases in Outer Membrane Cardiolipin.
Junping Fan, Erik Petersen, Thomas R. Hinds, Ning Zheng, Samuel I. Miller> ;Mbio. 2020 Feb 11
50 citations
Fecal dysbiosis in infants with cystic fibrosis is associated with early linear growth failure.
Hillary S. Hayden, Alexander Eng, Christopher E. Pope, Mitchell J. Brittnacher, Anh T. Vo, Eli J. Weiss, Kyle R. Hager, Bryan D Martin, Daniel H. Leung, Sonya L. Helts...> ;Nature Medicine. 2020 Jan 20
3 citations
Xenophagy: Pathogen-Containing Vacuoles Are Hard to Digest.
Anu Chaudhary, Samuel I. Miller> ;Current Biology. 2019 Oct 21
21 citations
Salmonella Translocated Effectors Recruit OSBP1 to the Phagosome to Promote Vacuolar Membrane Integrity.
Anna M. Kolodziejek, Melissa A. Altura, Junping Fan, Erik Petersen, Matthew Cook, Peter S. Brzovic, Samuel I. Miller> ;Cell Reports. 2019 May 14
30 citations
Cyclic-di-GMP regulation promotes survival of a slow-replicating subpopulation of intracellular Salmonella Typhimurium.
Erik Petersen, Erez Mills, Samuel I. Miller> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Mar 26
Dietary Therapy for Clostridium Difficile Colonization: A case series.
Suskind, D. L.,Lee, D.,Solan, P.,Wahbeh, G.,Hayden, H.,Brittnacher, M.,Nuding, M.,Miller, S.> ;Anaerobe. 2019 Mar 04
Human and Extracellular DNA Depletion for Metagenomic Analysis of Complex Clinical Infection Samples Yields Optimized Viable Microbiome Profiles.
Nelson, M. T.,Pope, C. E.,Marsh, R. L.,Wolter, D. J.,Weiss, E. J.,Hager, K. R.,Vo, A. T.,Brittnacher, M. J.,Radey, M. C.,Hayden, H. S.,Eng, A.,Miller, S. I.,Borenstein...> ;Cell Rep. 2019 Feb 21
HASH(0x2eae280)
Kamischke, C.,Fan, J.,Bergeron, J.,Kulasekara, H. D.,Dalebroux, Z. D.,Burrell, A.,Kollman, J. M.,Miller, S. I.> ;Elife. 2019 Jan 15
4 citations
β-Barrel outer membrane proteins suppress mTORC2 activation and induce autophagic responses
Anu Chaudhary, Cassandra Kamischke, Mara Leite, Melissa A. Altura, Loren Kinman, Hemantha D. Kulasekara, Marie-Pierre Blanc, Guoxing Wang, Cox Terhorst, Samuel I. Miller> ;Science Signaling. 2018 Nov 27
Identification of Small Molecule Modulators of Diguanylate Cyclase by FRET-based High-Throughput-Screening.
Christen, M.,Kamischke, C.,Kulasekara, H. D.,Olivas, K. C.,Kulasekara, B. R.,Christen, B.,Kline, T.,Miller, S. I.> ;Chembiochem. 2018 Nov 06
Inhibiting the Evolution of Antibiotic Resistance.
Ragheb, M. N.,Thomason, M. K.,Hsu, C.,Nugent, P.,Gage, J.,Samadpour, A. N.,Kariisa, A.,Merrikh, C. N.,Miller, S. I.,Sherman, D. R.,Merrikh, H.> ;Mol. Cell. 2018 Nov 20
15 citations
Multidrug-Resistant Acinetobacter baumannii Chloramphenicol Resistance Requires an Inner Membrane Permease.
Andrew P.-A. Karalewitz, Samuel I. Miller> ;Antimicrobial Agents and Chemotherapy. 2018 Jul 27
29 citations
Adaptation of commensal proliferating Escherichia coli to the intestinal tract of young children with cystic fibrosis.
Susana Matamouros, Hillary S. Hayden, Kyle R. Hager, Mitchell J. Brittnacher, K. Lachance, Eli J. Weiss, Christopher E. Pope, Anne-Flore Imhaus, Colin P. McNally, Elha...> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Feb 13
The gram-negative bacterial periplasm: Size matters.
Miller, S. I.,Salama, N. R.> ;PLoS Biol.. 2018 Jan 18
Multi-drug resistant non-typhoidal Salmonella associated with invasive disease in western Kenya.
Akullian, A.,Montgomery, J. M.,John-Stewart, G.,Miller, S. I.,Hayden, H. S.,Radey, M. C.,Hager, K. R.,Verani, J. R.,Ochieng, J. B.,Juma, J.,Katieno, J.,Fields, B.,Bigo...> ;PLoS Negl Trop Dis. 2018 Jan 13
92 citations
Antibiotic Resistance and Regulation of the Gram-Negative Bacterial Outer Membrane Barrier by Host Innate Immune Molecules.
Samuel I. Miller> ;Mbio. 2016 Nov 2
7 citations
Human Diversity in a Cell Surface Receptor that Inhibits Autophagy
Anu Chaudhary, Mara Leite, Bridget R. Kulasekara, Melissa A. Altura, Cassandra Ogahara, Eli J. Weiss, Wenqing Fu, Marie-Pierre Blanc, Michael O'Keeffe, Cox Terhorst, J...> ;Current Biology. 2016 Jul 25
6 citations
A Cellular GWAS Approach to Define Human Variation in Cellular Pathways Important to Inflammation.
Samuel I. Miller, Anu Chaudhary> ;Pathogens. 2016 Apr 26
17 citations
Genomic Analysis of Salmonella enterica Serovar Typhimurium Characterizes Strain Diversity for Recent U.S. Salmonellosis Cases and Identifies Mutations Linked to Loss ...
Hillary S. Hayden, Susana Matamouros, Kyle R. Hager, Mitchell J. Brittnacher, Laurence Rohmer, Matthew C. Radey, Eli J. Weiss, Katie B. Kim, Michael A. Jacobs, Elizabe...> ;Mbio. 2016 May 4
74 citations
Metagenomic evidence for taxonomic dysbiosis and functional imbalance in the gastrointestinal tracts of children with cystic fibrosis.
Ohad Manor, Roie Levy, Christopher E. Pope, Hillary S. Hayden, Mitchell J. Brittnacher, Rogan Carr, Matthew C. Radey, Kyle R. Hager, Sonya L. Heltshe, Bonnie W. Ramsey...> ;Scientific Reports. 2016 Mar 4
49 citations
S. Typhimurium strategies to resist killing by cationic antimicrobial peptides.
Susana Matamouros, Samuel I. Miller> ;Biochimica Et Biophysica Acta. 2015 Jan 30
53 citations
Low Level Engraftment and Improvement following a Single Colonoscopic Administration of Fecal Microbiota to Patients with Ulcerative Colitis
Christopher J. Damman, Mitchell J. Brittnacher, Maria Westerhoff, Hillary S. Hayden, Matthew C. Radey, Kyle R. Hager, Sara R. Marquis, Samuel I. Miller, Timothy L. Zisman> ;Plos One. 2015 Aug 19
58 citations
A direct screen for c-di-GMP modulators reveals a Salmonella Typhimurium periplasmic ʟ-arginine-sensing pathway.
Erez Mills, Erik Petersen, Bridget R. Kulasekara, Samuel I. Miller> ;Science Signaling. 2015 Jun 9
38 citations
HAMP Domain Rotation and Tilting Movements Associated with Signal Transduction in the PhoQ Sensor Kinase
Susana Matamouros, Kyle R. Hager, Samuel I. Miller> ;Mbio. 2015 Jul 1
Join now to see all

Journal Articles

Short Article Inhibiting the Evolution of Antibiotic Resistance
Samuel I Miller, Mark N Ragheb, ScienceDirect
Adaptation of Commensal Proliferating Escherichia Coli to the Intestinal Tract of Young Children with Cystic Fibrosis
Samuel I Miller, Lucas R Hoffman, Proceedings of the National Academy of Sciences

Hospital Affiliations

UW Medicine/University of Washington Medical CenterSeattle, Washington