SandiAlexanderKweeMD

Nuclear Medicine • Honolulu, HI

Physician

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Office
1301 Punchbowl St
Nuclear Medicine Dept.
Honolulu, HI 96813
Phone+1 808-585-5466

Fax+1 808-537-7813
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Education & Training

University of HawaiiResidency, Internal Medicine, 1996 - 1999
University of Pittsburgh School of MedicineClass of 1996

Certifications & Licensure

HI State Medical License 1999 - 2026
WA State Medical License 2000 - 2002
American Board of Nuclear Medicine Nuclear Medicine

Clinical Trials

Measurement of Anti-Androgen Response Using Fluorine-18 Fluorocholine PET/CT in Androgen-Insensitive Prostate Cancer Start of enrollment: 2009 Jun 01
Completed
Phase 1, Phase 2
Chemotherapy Response Monitoring With 18F-choline PET/CT in Hormone Refractory Prostate Cancer Start of enrollment: 2009 Jun 01
Completed
Phase 1, Phase 2
PET/CT in Diagnosing Patients With Liver Cancer Undergoing Surgical Resection Start of enrollment: 2011 Aug 15
Completed
Phase 2
Evaluation of Treatment Predictors Reflecting Beta-catenin Activation in Hepatocellular Carcinoma Start of enrollment: 2022 Mar 28
Recruiting
Phase 2
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

3 citations
Liver Transplantation vs Partial Hepatectomy for Stage T2 Multifocal Hepatocellular Carcinoma <3 cm Without Vascular Invasion: A Propensity Score-Matched Survival Anal...
Linda L Wong, Douglas P Landsittel, Sandi A Kwee> ;Journal of the American College of Surgeons. 2023 Sep 1
Hepatocellular carcinoma in Pacific Islanders: comparison of Pacific Island-born. US-born.
Shelby K Yee, Brenda Y Hernandez, Sandi Kwee, Linda L Wong> ;Hepatoma Research. 2023 Jan 1
1 citations
Target Trial Emulation: A Design Tool for Cancer Clinical Trials.
Sandi A Kwee, Linda L Wong, Christina Ludema, Chris K Deng, Deborah Taira, Todd Seto, Douglas Landsittel> ;JCO Clinical Cancer Informatics. 2023 Jan 1
Immunotherapy biomarkers for HCC: contemporary challenges and emerging opportunities.
Sandi Kwee, Xin Chen> ;Hepatoma Research. 2022 Jan 1
5 citations
Transarterial Radioembolization for Hepatocellular Carcinoma with Major Vascular Invasion: A Nationwide Propensity Score-Matched Analysis with Target Trial Emulation.
Sandi A. Kwee, Linda L. Wong, Miles M. Sato, Jared David Acoba, Young Soo Rho, Avantika Srivastava, Douglas Landsittel> ;Journal of Vascular and Interventional Radiology. 2021 Jul 6
1 citations
Factors and Survival Implications associated with biopsy of hepatocellular carcinoma.
Young S. Rho, Ian Pagano, Linda L. Wong, Sandi A. Kwee, Jared David Acoba> ;HPB. 2021 Jul 1
15 citations
Beta-catenin activation and immunotherapy resistance in hepatocellular carcinoma: mechanisms and biomarkers.
Sandi A. Kwee, Maarit Tiirikainen> ;Hepatoma Research. 2021 Jan 7
29 citations
Serum metabolite profiles are associated with the presence of advanced liver fibrosis in Chinese patients with chronic hepatitis B viral infection
Guoxiang Xie, Xiaoning Wang, Runmin Wei, Jingye Wang, Aihua Zhao, Tianlu Chen, Yixing Wang, Hua Zhang, Zhun Xiao, Xinzhu Liu, Youping Deng, Linda Wong, Cynthia Rajani,...> ;BMC Medicine. 2020 Jun 5
9 citations
Phospholipids are A Potentially Important Source of Tissue Biomarkers for Hepatocellular Carcinoma: Results of a Pilot Study Involving Targeted Metabolomics.
Erin B Evangelista, Sandi A. Kwee, Miles M. Sato, Lu Wang, Christoph Rettenmeier, Guoxiang Xie, Wei Jia, Linda L. Wong> ;Diagnostics. 2019 Oct 29
42 citations
Ursodeoxycholic acid accelerates bile acid enterohepatic circulation.
Yunjing Zhang, Runqiu Jiang, Xiaojiao Zheng, Sha Lei, Fengjie Huang, Guoxiang Xie, Sandi A. Kwee, Herbert Yu, Christine Farrar, Beicheng Sun, Aihua Zhao, Wei Jia> ;British Journal of Pharmacology. 2019 Aug 1
22 citations
Underlying liver disease and advanced stage liver cancer are associated with elevated neutrophil-lymphocyte ratio.
Linda Wong, Kliment Bozhilov, Brenda Y. Hernandez, Sandi A. Kwee, Owen Chan, Luke Ellis, Loic LeMarchand> ;Clinical and Molecular Hepatology. 2019 Apr 19
10 citations
Transcriptomics Associates Molecular Features with 18F-Fluorocholine PET/CT Imaging Phenotype and Its Potential Relationship to Survival in Hepatocellular Carcinoma.
Sandi A. Kwee, Maarit Tiirikainen, Miles M. Sato, Jared David Acoba, Runmin Wei, Wei Jia, Loic Le Marchand, Linda L. Wong> ;Cancer Research. 2019 Apr 1
83 citations
Gender differences in hepatocellular cancer: disparities in nonalcoholic fatty liver disease/steatohepatitis and liver transplantation.
Eric M. Wu, Linda L. Wong, Brenda Y. Hernandez, Jun-Fang Ji, Wei Jia, Sandi A. Kwee, Sumodh Kalathil> ;Hepatoma Research. 2018 Oct 18
47 citations
Clinical prediction of HBV and HCV related hepatic fibrosis using machine learning.
Runmin Wei, Jingye Wang, Xiaoning Wang, Guoxiang Xie, Yixing Wang, Hua Zhang, Cheng Yuan Peng, Cynthia Rajani, Sandi A. Kwee, Ping Liu, Wei Jia> ;Ebiomedicine. 2018 Sep 1
15 citations
Clinical and molecular sub-classification of hepatocellular carcinoma relative to alpha-fetoprotein level in an Asia-Pacific island cohort
Scott T. Nishioka, Miles M. Sato, Linda L. Wong, Maarit Tiirikainen, Sandi A. Kwee> ;Hepatoma Research. 2018 Jan 12
11 citations
PET/CT with 18F Fluorocholine as an Imaging Biomarker for Chronic Liver Disease: A Preliminary Radiopathologic Correspondence Study in Patients with Liver Cancer
Sandi A. Kwee, Linda Wong, Owen T. M. Chan, Sumodh Kalathil, Naoky Tsai> ;Radiology. 2018 Jan 9
11 citations
Late recurrence of hepatocellular carcinoma after liver transplantation.
Julia A Zhang, Sandi A. Kwee, Linda L. Wong> ;Hepatoma Research. 2017 Apr 10
13 citations
Soft Tissue Response on 18F-Fluorocholine PET/CT in Metastatic Castrate-Resistant Prostate Cancer Treated With 223Ra-Dichloride: A Possible Abscopal Effect?
Sandi A. Kwee, John Lim, Marc N. Coel> ;Clinical Nuclear Medicine. 2017 Nov 1
35 citations
Pitfalls in surveillance for hepatocellular carcinoma: How successful is it in the real world?
Linda L. Wong, Ruel Reyes, Sandi A. Kwee, Brenda Y. Hernandez, Sumodh Kalathil, Naoky Tsai> ;Clinical and Molecular Hepatology. 2017 Jul 14
17 citations
[ 18 F]Fluorocholine PET/CT Imaging of Liver Cancer: Radiopathologic Correlation with Tissue Phospholipid Profiling.
Sandi A. Kwee, Miles M. Sato, Yu Kuang, Adrian A. Franke, L J Custer, Kyle Miyazaki, Linda L. Wong> ;Molecular Imaging and Biology. 2017 Jun 1
3 citations
Metabolic positron emission tomography imaging of cancer: Pairing lipid metabolism with glycolysis.
Sandi A. Kwee, John Lim> ;World Journal of Radiology. 2016 Nov 28
5 citations
Joint analysis of multiple high-dimensional data types using sparse matrix approximations of rank-1 with applications to ovarian and liver cancer
Gordon Okimoto, Ashkan Zeinalzadeh, Tom Wenska, Michael Loomis, James B. Nation, Tiphaine Fabre, Maarit Tiirikainen, Brenda Y. Hernandez, Owen Chan, Linda Wong, Sandi ...> ;Biodata Mining. 2016 Jul 29
11 citations
Comparison of genome-scale DNA methylation profiles in hepatocellular carcinoma by viral status.
Min-Ae Song, Sandi A. Kwee, Maarit Tiirikainen, Brenda Y. Hernandez, Gordon Okimoto, Naoky Tsai, Linda L. Wong, Herbert Yu> ;Epigenetics. 2016 Jun 1
4 citations
Metabolic characteristics distinguishing intrahepatic cholangiocarcinoma: a negative pilot study of (18)F-fluorocholine PET/CT clarified by transcriptomic analysis.
Sandi A. Kwee, Gordon Okimoto, Owen Tm Chan, Maarit Tiirikainen, Linda L. Wong> ;American Journal of Nuclear Medicine and Molecular Imaging. 2016 Jan 28
12 citations
Prediction of PSA Progression in Castration-Resistant Prostate Cancer Based on Treatment-Associated Change in Tumor Burden Quantified by 18F-Fluorocholine PET/CT
Joohee Lee, Miles M. Sato, Marc N. Coel, Kyung-Han Lee, Sandi A. Kwee> ;Journal of Nuclear Medicine. 2016 Feb 16
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Hospital Affiliations

The Queen's Medical CenterHonolulu, Hawaii
Straub Medical CenterHonolulu, Hawaii

SandiAlexanderKweeMD

Dr. Kwee is on Doximity

Education & Training

Certifications & Licensure

Clinical Trials

Publications & Presentations

Hospital Affiliations

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