SantiagoBoPluradDOFACOP, FAAP

Pediatrics • Fenton, MO

Adolescent Medicine

Pediatrician, SSM Health Medical Group, Fenton, MO

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Office
SSM Health Medical Group Pediatrics
1345 Smizer Mill Rd
Fenton, MO 63026
Phone+1 636-496-5021

Fax+1 636-496-5015
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Education & Training

St Louis University School of MedicineResidency, Pediatrics, 1988 - 1991
Kansas City University GME Consortium (KCU-GME Consortium)/St Luke's Des PereInternship, Transitional Year, 1987 - 1988
A. T. Still University Kirksville College of Osteopathic MedicineClass of 1987
Washington University in St. LouisAB, psych, biology, 1978 - 1982

Certifications & Licensure

MO State License 1989 - 2025
AOA Board of Pediatrics Adolescent & Young Adult Medicine
AOA Board of Pediatrics Pediatrics

Awards, Honors, & Recognition

Best Doctors of St. Louis St. Louis Magazine, 2008-2016, 2018-2019
Physician Teaching Award Cardinal Glennon Childrens Hospital, 2005-2006

Publications & Presentations

PubMed

56 citations
Non-obese diabetic mice rapidly develop dramatic sympathetic neuritic dystrophy: a new experimental model of diabetic autonomic neuropathy
Robert E. Schmidt, Denise A. Dorsey, Lucie N. Beaudet, Kathy E. Frederick, Curtis A. Parvin, Santiago B. Plurad, Matteo G. Levisetti> ;The American Journal of Pathology. 2003 Nov 1
20 citations
Inhibition of sorbitol dehydrogenase exacerbates autonomic neuropathy in rats with streptozotocin-induced diabetes.
Robert E. Schmidt, Denise A. Dorsey, Lucie N. Beaudet, Santiago B. Plurad, Curtis A. Parvin, Kevin E. Yarasheski, Samuel R. Smith, Hans-Jochen Lang, Joseph R. Williams...> ;Journal of Neuropathology and Experimental Neurology. 2001 Dec 1
6 citations
Effect of IGF-I and neurotrophin-3 on gracile neuroaxonal dystrophy in diabetic and aging rats.
Robert E. Schmidt, Denise A. Dorsey, Lucie N. Beaudet, Santiago B. Plurad, Curtis A. Parvin, Shinji Ohara> ;Brain Research. 2000 Sep 8
67 citations
Insulin-like growth factor I reverses experimental diabetic autonomic neuropathy.
Robert E. Schmidt, Denise A. Dorsey, Lucie N. Beaudet, Santiago B. Plurad, Curtis A. Parvin, Matthew S. Miller> ;The American Journal of Pathology. 1999 Nov 1
18 citations
Effect of sorbitol dehydrogenase inhibition on experimental diabetic autonomic neuropathy.
Robert E. Schmidt, Denise A. Dorsey, Lucie N. Beaudet, Santiago B. Plurad, Joseph R. Williamson, Yasuo Ido> ;Journal of Neuropathology and Experimental Neurology. 1998 Dec 1
9 citations
Vacuolar neuritic dystrophy in aged mouse superior cervical sympathetic ganglia is strain-specific.
Robert E. Schmidt, Denise A. Dorsey, Lucie N. Beaudet, Santiago B. Plurad, Curtis A. Parvin, Leslie A. Bruch> ;Brain Research. 1998 Sep 28
55 citations
Axonal cytoskeletal pathology in aged and diabetic human sympathetic autonomic ganglia.
Robert E. Schmidt, Lucie N. Beaudet, Santiago B. Plurad, Denise A. Dorsey> ;Brain Research. 1997 Sep 26
50 citations
Dystrophic axonal swellings develop as a function of age and diabetes in human dorsal root ganglia.
Robert E. Schmidt, Denise A. Dorsey, Curtis A. Parvin, Lucie N. Beaudet, Santiago B. Plurad, Kevin A. Roth> ;Journal of Neuropathology and Experimental Neurology. 1997 Sep 1
17 citations
Pathologic alterations in pre- and postsynaptic elements in aged mouse sympathetic ganglia.
Robert E. Schmidt, Lucien Beaudet, Santiago B. Plurad, William D. Snider, Kenneth G. Ruit> ;Journal of Neurocytology. 1995 Mar 1
63 citations
Effect of diabetes and aging on human sympathetic autonomic ganglia
Robert E. Schmidt, Santiago B. Plurad, Curtis A. Parvin, Kevin A. Roth> ;The American Journal of Pathology. 1993 Jul 1
21 citations
Fine structure of presynaptic axonal terminals in sympathetic autonomic ganglia of aging and diabetic human subjects.
Jo Anna Schroer, Santiago B. Plurad, Robert E. Schmidt> ;Synapse. 1992 Sep 1
24 citations
Effects of Sorbinil, Dietary myo-Inositol Supplementation, and Insulin on Resolution of Neuroaxonal Dystrophy in Mesenteric Nerves of Streptozocin-Induced Diabetic Rats
Robert E. Schmidt, Santiago B. Plurad, Bill D. Coleman, Joseph R. Williamson, Ronald G. Tilton> ;Diabetes. 1991 May 1
9 citations
The effect of pancreatic islet transplantation and insulin therapy on neuroaxonal dystrophy in sympathetic autonomic ganglia of chronic streptozocin-diabetic rats.
Robert E. Schmidt, Santiago B. Plurad, Barbara Olack, David W. Scharp> ;Brain Research. 1989 Sep 18
32 citations
Ultrastructural and immunohistochemical characterization of autonomic neuropathy in genetically diabetic Chinese hamsters.
Robert E. Schmidt, D A Plurad, Santiago B. Plurad, B E Cogswell, A R Diani, K A Roth> ;Laboratory Investigation; a Journal of Technical Methods and Pathology. 1989 Jul 1
32 citations
Effects of aldose reductase inhibitor sorbinil on neuroaxonal dystrophy and levels of myo-inositol and sorbitol in sympathetic autonomic ganglia of streptozocin-induce...
Robert E. Schmidt, Santiago B. Plurad, William R. Sherman, Joseph R. Williamson, Ronald G. Tilton> ;Diabetes. 1989 May 1
5 citations
Sympathetic neuronal destruction in macaque monkeys by guanethidine and guanacline.
Margaret A. Palmatier, Robert E. Schmidt, Santiago B. Plurad, Eugene M. Johnson> ;Annals of Neurology. 1987 Jan 1
72 citations
Ultrastructural and Biochemical Characterization of Autonomic Neuropathy in Rats with Chronic Streptozotocin Diabetes
Robert E. Schmidt, Santiago B. Plurad> ;Journal of Neuropathology and Experimental Neurology. 1986 Sep 1
36 citations
Retrograde axonal transport of 125I-nerve growth factor in rat ileal mesenteric nerves: effect of streptozocin diabetes
Robert E. Schmidt, Santiago B. Plurad, Jeffrey E. Saffitz, Gary G. Grabau, Henry K. Yip> ;Diabetes. 1985 Dec 1
26 citations
Ultrastructural appearance of intentionally frustrated axonal regeneration in rat sciatic nerve.
Robert E. Schmidt, Santiago B. Plurad> ;Journal of Neuropathology and Experimental Neurology. 1985 Mar 1
74 citations
Experimental diabetic autonomic neuropathy characterization in streptozotocin-diabetic Sprague-Dawley rats.
Robert E. Schmidt, S B Plurad, C W Modert> ;Laboratory Investigation; a Journal of Technical Methods and Pathology. 1983 Nov 1
41 citations
Neuroaxonal dystrophy in the autonomic ganglia of aged rats.
Robert E. Schmidt, Santiago B. Plurad, Christopher W. Modert> ;Journal of Neuropathology and Experimental Neurology. 1983 Jul 1
54 citations
The Effect of Pancreatic Islet Transplantation and Insulin Therapy on Experimental Diabetic Autonomic Neuropathy
Robert E. Schmidt, Santiago B. Plurad, Barbara Olack, David W. Scharp> ;Diabetes. 1983 Jun 1
81 citations
Mutations in the unc-54 myosin heavy chain gene of caenorhabditis elegans that alter contractility but not muscle structure
Donald G. Moerman, Santiago B. Plurad, Robert H. Waterston, David L. Baillie> ;Cell. 1982 Jul 1
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Professional Memberships

American Osteopathic Association - AOA
Member
American Academy of Pediatrics - AAP
Fellow

Other Languages

Spanish

Hospital Affiliations

SSM Health Cardinal Glennon Children’s HospitalSaint Louis, Missouri
SSM Health St. Clare Hospital - FentonFenton, Missouri