ScottAWatkinsMD

PubMed

• Improved spatial resolution of matrix-assisted laser desorption/ionization imaging of lipids in the brain by alkylated derivatives of 2,5-dihydroxybenzoic acid.
  Stoyanovsky, D. A.,Sparvero, L. J.,Amoscato, A. A.,He, R. R.,Watkins, S.,Pitt, B. R.,Bayir, H.,Kagan, V. E.> ;Rapid Commun. Mass Spectrom.. 2014 Feb 06
• 30 citations
  Structure-based design of a new class of highly selective aminoimidazo[1,2-a]pyridine-based inhibitors of cyclin dependent kinases.
  Chafiq Hamdouchi, Boyu Zhong, Jose S. Mendoza, Elizabeth Collins, C. Jaramillo, José Eugenio de Diego, Daniel H. Robertson, Charles D. Spencer, Bryan D. Anderson, Scot...> ;Bioorganic & Medicinal Chemistry Letters. 2005 Apr 1
• 81 citations
  Kinetic characterization of novel pyrazole TGF-beta receptor I kinase inhibitors and their blockade of the epithelial-mesenchymal transition.
  Sheng-Bin Peng, Lei Yan, Xiaoling Xia, Scott A. Watkins, Brooks Harold Burns, Beight Douglas W, David Kent Herron, Michael L. Jones, John W. Lampe, William Thomas Mcmi...> ;Biochemistry. 2005 Jan 27
• 20 citations
  Aminoimidazo[1,2-a]pyridines as a new structural class of cyclin-dependent kinase inhibitors. Part 1: Design, synthesis, and biological evaluation.
  Carlos Jaramillo, J. Eugenio de Diego, Chafiq Hamdouchi, Elizabeth Collins, Heather Keyser, Concha Sanchez-Martinez, Miriam del Prado, Bryan H. Norman, Harold B. Brook...> ;Bioorganic & Medicinal Chemistry Letters. 2004 Dec 20
• 10 citations
  Preparation of novel aza-1,7-annulated indoles and their conversion to potent indolocarbazole kinase inhibitors.
  Rima S. Al-awar, James Edward Ray, Kyle Andrew Hecker, Sajan Joseph, Jianping Huang, Chuan Shih, Harold B. Brooks, Charles D. Spencer, Scott A. Watkins, Richard M. Sch...> ;Bioorganic & Medicinal Chemistry Letters. 2004 Aug 2
• 11 citations
  1,7-annulated indolocarbazoles as cyclin-dependent kinase inhibitors.
  Rima S. Al-awar, James Edward Ray, Kyle Andrew Hecker, Jianping Huang, Philip Parker Waid, Chuan Shih, Harold B. Brooks, Charles D. Spencer, Scott A. Watkins, Bharvin ...> ;Bioorganic & Medicinal Chemistry Letters. 2004 Jun 21
• 18 citations
  Synthesis of 1,7-annulated indoles and their applications in the studies of cyclin dependent kinase inhibitors.
  Guoxin Zhu, Scott Eugene Conner, Xun Zhou, Ho-Kit Chan, Chuan Shih, Thomas A. Engler, Rima S. Al-awar, Harold B. Brooks, Scott A. Watkins, Charles D. Spencer, Richard ...> ;Bioorganic & Medicinal Chemistry Letters. 2004 Jun 21
• 24 citations
  The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo[1,2-a]pyridines
  Chafiq Hamdouchi, Heather Keyser, Elizabeth Collins, Carlos Jaramillo, José Eugenio de Diego, Charles D. Spencer, Jack A. Dempsey, Bryan D. Anderson, Tillie Leggett, N...> ;Molecular Cancer Therapeutics. 2004 Jan 1
• 23 citations
  Studies on cyclin-dependent kinase inhibitors: indolo-[2,3-a]pyrrolo[3,4-c]carbazoles versus bis-indolylmaleimides.
  Concha Sanchez-Martinez, Chuan Shih, Guoxin Zhu, Tiechao Li, Harold B. Brooks, Bharvin K. R. Patel, Richard M. Schultz, Tammy B. DeHahn, Charles D. Spencer, Scott A. W...> ;Bioorganic & Medicinal Chemistry Letters. 2003 Nov 3
• 34 citations
  Aryl[a]pyrrolo[3,4-c]carbazoles as selective cyclin D1-CDK4 inhibitors.
  Concha Sanchez-Martinez, Chuan Shih, Margaret M. Faul, Guoxin Zhu, Michael Paal, Carmen Somoza, Tiechao Li, Christine A. Kumrich, Leonard L. Winneroski, Zhou Xun, Haro...> ;Bioorganic & Medicinal Chemistry Letters. 2003 Nov 3
• 40 citations
  Novel, potent and selective cyclin D1/CDK4 inhibitors: indolo[6,7-a]pyrrolo[3,4-c]carbazoles.
  Thomas A. Engler, Kelly Wayne Furness, Sushant Malhotra, Concha Sanchez-Martinez, Chuan Shih, Walter Xie, Guoxin Zhu, Xun Zhou, Scott Eugene Conner, Margaret M. Faul, ...> ;Bioorganic & Medicinal Chemistry Letters. 2003 Jul 21
• 68 citations
  Synthesis, Structure−Activity Relationship, and Biological Studies of Indolocarbazoles as Potent Cyclin D1-CDK4 Inhibitors
  Guoxin Zhu, Scott Eugene Conner, Xun Zhou, Chuan Shih, Tiechao Li, Bryan D. Anderson, Harold B. Brooks, Robert M. Campbell, Eileen L. Considine, Jack A. Dempsey, Marga...> ;Journal of Medicinal Chemistry. 2003 May 22
• 24 citations
  Synthesis of quinolinyl/isoquinolinyl[a]pyrrolo [3,4-c] carbazoles as cyclin D1/CDK4 inhibitors.
  Guoxin Zhu, Scott Eugene Conner, Xun Zhou, Chuan Shih, Harold B. Brooks, Eileen L. Considine, Jack A. Dempsey, Cathy Ogg, Bharvin K. R. Patel, Richard M. Schultz, Char...> ;Bioorganic & Medicinal Chemistry Letters. 2003 Apr 7
• Cryosectioning.
  Watkins, S.> ;Curr Protoc Pharmacol. 2001 May 01
• 18 citations
  Conditional transformation of rat embryo fibroblast cells by a cyclin D1-cdk4 fusion gene.
  R.Nagaraja Rao, Nancy B. Stamm, Keith A. Otto, Steve Kovacevic, Scott A. Watkins, Pam Rutherford, Stephanie J. Lemke, Kim Cocke, Richard P. Beckmann, Keith A. Houck, D...> ;Oncogene. 1999 Nov 4
• NOX, a novel nitric oxide scavenger, reduces bacterial translocation in rats after endotoxin challenge.
  Dickinson E, Tuncer R, Nadler E, Boyle P, Alber S, Watkins S, Ford H> ;Am. J. Physiol.. 1999-12-01
• Hemorrhagic shock induces G-CSF expression in bronchial epithelium.
  Hierholzer C, Kelly E, Tsukada K, Loeffert E, Watkins S, Billiar TR, Tweardy DJ> ;Am. J. Physiol.. 1997-11-01
• Overexpression of metallothionein decreases sensitivity of pulmonary endothelial cells to oxidant injury.
  Pitt BR, Schwarz M, Woo ES, Yee E, Wasserloos K, Tran S, Weng W, Mannix RJ, Watkins SA, Tyurina YY, Tyurin VA, Kagan VE, Lazo JS> ;Am. J. Physiol.. 1997-10-01
• Nitric oxide inhibits lipopolysaccharide-induced apoptosis in pulmonary artery endothelial cells.
  Ceneviva, G. D., Tzeng, E., Hoyt, D. G., Yee, E., Gallagher, A., Engelhardt, J. F., Kim, Y. M., Billiar, T. R., Watkins, S. A., Pitt, B. R.> ;Am J Physiol. 1998 Oct
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