ShrutiMukundRajaMD

PubMed

• Intravenous Ganaxolone: Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability in Healthy Adults.
  Maciej Gasior, Aatif Husain, Megan E Barra, Shruti M Raja, David MacLeod, Jeffrey T Guptill, Henrikas Vaitkevicius, Eva Rybak> ;Clinical Pharmacology in Drug Development. 2024 Mar 1
• 1 citations
  Experience of Daily Life with Generalized Myasthenia Gravis: A Qualitative Investigation and Assessment of Instrument Content Validity.
  Christopher A Hartford, Steven A Sherman, Stella Karantzoulis, Isabelle Guillemin, Michael G Phinney, Kimberly L Kelly, Kayla E Negron, Shruti M Raja, Diana Rofail> ;Neurology and Therapy. 2023 Dec 1
• 2 citations
  Pregnancy in MuSK-positive myasthenia gravis: A single-center case series.
  Yohei Harada, Margaret Bettin, Vern C Juel, Lisa D Hobson-Webb, Shruti M Raja, Donald B Sanders, Janice M Massey> ;Muscle & Nerve. 2023 Jul 1
• 2 citations
  The Duke Myasthenia Gravis Clinic Registry: II. Analysis of outcomes.
  Donald B Sanders, Michael W Lutz, Shruti M Raja, Vern C Juel, Jeffrey T Guptill, Lisa D Hobson-Webb, Janice M Massey> ;Muscle & Nerve. 2023 Apr 1
• 6 citations
  Safety of Ceftazidime-Avibactam in Combination with Aztreonam (COMBINE) in a Phase I, Open-Label Study in Healthy Adult Volunteers.
  Thomas P Lodise, J Nicholas O'Donnell, Shruti Raja, Jeffrey T Guptill, Smitha Zaharoff, Nyssa Schwager, Vance G Fowler Jr, Tatiana Beresnev, Alison Wall, Katherine Wie...> ;Antimicrobial Agents and Chemotherapy. 2022 Dec 20
• 7 citations
  Pharmacokinetics of Ceftazidime-Avibactam in Combination with Aztreonam (COMBINE) in a Phase 1, Open-Label Study of Healthy Adults.
  Thomas P Lodise, J Nicholas O'Donnell, Stephen Balevic, Xing Liu, Kenan Gu, Jomy George, Shruti Raja, Jeffrey T Guptill, Smitha Zaharoff, Nyssa Schwager, Vance G Fowle...> ;Antimicrobial Agents and Chemotherapy. 2022 Dec 20
• Steroid Use and Perioperative Complications of Thymectomy in Myasthenia Gravis.
  Shruti M Raja> ;The Annals of Thoracic Surgery. 2023 Jun 1
• 16 citations
  Classical Complement Pathway Inhibition in a "Human-On-A-Chip" Model of Autoimmune Demyelinating Neuropathies.
  John W Rumsey, Case Lorance, Max Jackson, Trevor Sasserath, Christopher W McAleer, Christopher J Long, Arindom Goswami, Melissa A Russo, Shruti M Raja, Karissa L Gable...> ;Advanced Therapeutics. 2022 Jun 1
• 6 citations
  First-in-Human Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of Single Doses of NTM-1633, a Novel Mixture of Monoclonal Antibodies against Bot...
  S M Raja, J T Guptill, V C Juel, E B Walter, M Cohen-Wolkowiez, H Hill, E Sendra, B Hauser, P Jackson, M Tomic, Y Espinoza, G K Swamy> ;Antimicrobial Agents and Chemotherapy. 2022 Apr 19
• 2 citations
  Adverse Reactions in a Phase 1 Trial of the Anti-Malarial DM1157: An Example of Pharmacokinetic Modeling and Simulation Guiding Clinical Trial Decisions.
  Stephen J Balevic, Shruti M Raja, Rachel Randell, Gregory A Deye, Thomas Conrad, Aya Nakamura, David H Peyton, Sandra Shotwell, Katherine Liebman, Michael Cohen-Wolkow...> ;Infectious Diseases and Therapy. 2022 Apr 1
• Evaluation of a Digital Handheld Hydrogen Breath Monitor to Diagnose Lactose Malabsorption: Interventional Crossover Study.
  Simon C. Mathews, Sandy Templeton, Stephanie K Taylor, Sten Harris, Margaret Stewart, Shruti M. Raja> ;JMIR Formative Research. 2021 Oct 18
• 7 citations
  Perioperative Outcomes of Thymectomy in Myasthenia Gravis: A Thoracic Surgery Database Analysis
  Shruti M. Raja, Jeffrey T. Guptill, Alec McConnell, Hussein R. Al-Khalidi, Matthew G. Hartwig, Jacob A. Klapper> ;The Annals of Thoracic Surgery. 2021 Jul 30
• 7 citations
  Safety, Tolerability, and Pharmacokinetics of NTM-1632, a Novel Mixture of Three Monoclonal Antibodies against Botulinum Toxin B.
  Jeffrey T. Guptill, Shruti M. Raja, Vern C. Juel, Emmanuel B. Walter, Michael Cohen-Wolkowiez, Heather Hill, Eli A. Sendra, B Hauser, Pearce Jackson, Geeta K. Swamy> ;Antimicrobial Agents and Chemotherapy. 2021 Jun 17
• 7 citations
  First-in-Human Studies of MW01-6-189WH, a Brain-Penetrant, Antineuroinflammatory Small-Molecule Drug Candidate: Phase 1 Safety, Tolerability, Pharmacokinetic, and Phar...
  Linda J. Van Eldik, Lumy Sawaki, Karen Bowen, Daniel T. Laskowitz, Robert J. Noveck, Byron Hauser, Lynn Jordan, Tracy Spears, Huali Wu, Kevin M. Watt, Shruti M. Raja, ...> ;Clinical Pharmacology in Drug Development. 2021 Feb 1
• 15 citations
  The Duke myasthenia gravis clinic registry: I. Description and demographics.
  Donald B. Sanders, Shruti M. Raja, Jeffrey T. Guptill, Lisa D. Hobson-Webb, Vern C. Juel, Janice M. Massey> ;Muscle & Nerve. 2021 Feb 1
• 2 citations
  Reduced plasmablast frequency is associated with seronegative myasthenia gravis.
  Jeffrey T. Guptill, Richard Barfield, Cliburn Chan, Melissa A. Russo, Doug Emmett, Shruti M. Raja, Janice M. Massey, Vern C. Juel, Lisa D. Hobson-Webb, Karissa L. Gabl...> ;Muscle & Nerve. 2020 Dec 24
• 11 citations
  KNOWLEDGE AND PERCEPTIONS OF THE COVID-19 PANDEMIC AMONG PATIENTS WITH MYASTHENIA GRAVIS
  Yingkai Li, C Douglas Emmett, Marjan Cobbaert, Donald B. Sanders, Vern C. Juel, Lisa D. Hobson-Webb, Janice M. Massey, Karissa L. Gable, Shruti M. Raja, Natalia Gonzal...> ;Muscle & Nerve. 2021 Mar 1
• 17 citations
  Imbalance in T follicular helper cells producing IL-17 promotes pro-inflammatory responses in MuSK antibody positive myasthenia gravis
  Yingkai Li, Jeffrey T. Guptill, Melissa A. Russo, James F. Howard, Janice M. Massey, Vern C. Juel, Lisa D. Hobson-Webb, Doug Emmett, Manisha Chopra, Shruti M. Raja, We...> ;Journal of Neuroimmunology. 2020 Aug 15
• 9 citations
  Inhibition of the transcription factor ROR-γ reduces pathogenic Th17 cells in acetylcholine receptor antibody positive myasthenia gravis.
  John S. Yi, Melissa A. Russo, Shruti M. Raja, Janice M. Massey, Vern C. Juel, Jay Shin, Lisa D. Hobson-Webb, Karissa L. Gable, Jeffrey T. Guptill> ;Experimental Neurology. 2020 Mar 1
• 10 citations
  Clinical outcome measures following plasma exchange for MG exacerbation.
  Shruti M. Raja, James F. Howard, Vern C. Juel, Janice M. Massey, Manisha Chopra, Jeffrey T. Guptill> ;Annals of Clinical and Translational Neurology. 2019 Oct 1
• 4 citations
  Validation of the triple timed up-and-go test in Lambert-Eaton myasthenia.
  Shruti M. Raja, Donald B. Sanders, Vern C. Juel, Yadollah Harati, A. Gordon Smith, Robert M. Pascuzzi, David P. Richman, Angie Wu, Kathy L. Aleš, Laura R. Jacobus, Dav...> ;Muscle & Nerve. 2019 Sep 1
• 5 citations
  Validation of a simple disease-specific, quality-of-life measure for diabetic polyneuropathy: CAPPRI
  Kelly G. Gwathmey, Reza Sadjadi, William B. Horton, Mark R. Conaway, Carolina Barnett-Tapia, Vera Bril, James W. Russell, Aziz Shaibani, Michelle L. Mauermann, Michael...> ;Neurology. 2018 Jun 5
• 3 citations
  Comparative effectiveness clinical trials to advance treatment of myasthenia gravis.
  Jeffrey T. Guptill, Shruti M. Raja, Donald B. Sanders, Pushpa Narayanaswami> ;Annals of the New York Academy of Sciences. 2018 Feb 1
• 9 citations
  Reliability of the triple-timed up-and-go test.
  Donald B. Sanders, Jeffrey T. Guptill, Kathy L. Aleš, Lisa D. Hobson-Webb, David P. Jacobus, Riaz Mahmood, Janice M. Massey, Melissa M. Pittman, Kristi Prather, Shruti...> ;Muscle & Nerve. 2018 Jan 1
• 30 citations
  Phase 1 Randomized, Double-Blind, Placebo-Controlled Study to Determine the Safety, Tolerability, and Pharmacokinetics of a Single Escalating Dose and Repeated Doses o...
  Jeffrey T. Guptill, Shruti M. Raja, Felix Boakye-Agyeman, Robert J. Noveck, Sarah Ramey, Tian Ming Tu, Daniel T. Laskowitz> ;Journal of Clinical Pharmacology. 2017 Jun 1
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