SinaAliasgnarGharibMD

PubMed

• Exploiting meta-analysis of genome-wide interaction with serum 25-hydroxyvitamin D to identify novel genetic loci associated with pulmonary function.
  Jungkyun Seo, Nathan C Gaddis, Bonnie K Patchen, Jiayi Xu, R Graham Barr, George O'Connor, Ani W Manichaikul, Sina A Gharib, Josée Dupuis, Kari E North, Patricia A Cas...> ;The American Journal of Clinical Nutrition. 2024 Mar 12
• A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations.
  Pavithra Nagarajan, Thomas W Winkler, Amy R Bentley, Clint L Miller, Aldi T Kraja, Karen Schwander, Songmi Lee, Wenyi Wang, Michael R Brown, John L Morrison, Ayush Gir...> ;Medrxiv. 2024 Mar 8
• HHV-6B detection and host gene expression implicate HHV-6B as pulmonary pathogen after hematopoietic cell transplant.
  Joshua A Hill, Yeon Joo Lee, Lisa K Vande Vusse, Hu Xie, E Lisa Chung, Alpana Waghmare, Guang-Shing Cheng, Haiying Zhu, Meei-Li Huang, Geoffrey R Hill, Keith R Jerome,...> ;Nature Communications. 2024 Jan 16
• Fatty acid metabolism promotes TRPV4 activity in lung microvascular endothelial cells in pulmonary arterial hypertension.
  Philip, N., Yun, X., Pi, H., Murray, S., Hill, Z., Fonticella, J., Perez, P., Zhang, C., Pathmasiri, W., Sumner, S., Servinsky, L., Jiang, H., Huetsch, J., Oldham, W.,...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2024 Mar 1
• Toll-interacting protein inhibits transforming growth factor beta signaling in mouse lung fibroblasts.
  Chow, Y., López-Martínez, C., Liles, W., Altemeier, W., Gharib, S., Hung, C.> ;FASEB Bioadvances. 2024 Jan 1
• 1 citations
  Genome-wide association study of preserved ratio impaired spirometry (PRISm).
  Higbee, D., Lirio, A., Hamilton, F., Granell, R., Wyss, A., London, S., Bartz, T., Gharib, S., Cho, M., Wan, E., Silverman, E., Crapo, J., Lominchar, J., Hansen, T., G...> ;The European Respiratory Journal. 2024 Jan 1
• 1 citations
  Plasma Metabolomics Reveals Distinct Biological and Diagnostic Signatures for Melioidosis.
  Lu Xia, Viriya Hantrakun, Prapit Teparrukkul, Gumphol Wongsuvan, Taniya Kaewarpai, Adul Dulsuk, Nicholas P J Day, Rozenn N Lemaitre, Narisara Chantratita, Direk Limmat...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Feb 1
• Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary...
  Nick Shrine, Abril G Izquierdo, Jing Chen, Richard Packer, Robert J Hall, Anna L Guyatt, Chiara Batini, Rebecca J Thompson, Chandan Pavuluri, Vidhi Malik, Brian D Hobb...> ;Nature Genetics. 2023 Oct 1
• Associations of Histamine Metabolites with Disease Severity and Mortality in Pulmonary Arterial Hypertension.
  Brandon S Peplinski, Jonathan Buber, Sina A Gharib, Hongyang Pi, Daniel Raftery, Peter J Leary> ;Annals of the American Thoracic Society. 2023 Nov 1
• Reanalysis of Single-Cell RNA-Sequencing Data in Patients with COVID-19: Insights and Limitations.
  Chi F Hung, Sina A Gharib> ;American Journal of Respiratory Cell and Molecular Biology. 2023 Dec 1
• Investigating Associations of Omega-3 Fatty Acids, Lung Function Decline, and Airway Obstruction.
  Bonnie K Patchen, Pallavi Balte, Traci M Bartz, R Graham Barr, Myriam Fornage, Mariaelisa Graff, David R Jacobs Jr, Ravi Kalhan, Rozenn N Lemaitre, George O'Connor, Br...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Oct 15
• 5 citations
  Distinct Epithelial-Innate Immune Cell Transcriptional Circuits Underlie Airway Hyperresponsiveness in Asthma.
  Ryan C Murphy, Ying Lai, Matthew Liu, Taha Al-Shaikhly, Matthew C Altman, William A Altemeier, Charles W Frevert, Jason S Debley, Adrian M Piliponsky, Steven F Ziegler...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Jun 15
• Plasma sphingolipids, lung function and COPD: the Cardiovascular Health Study.
  Arya R Gharib, Paul N Jensen, Bruce M Psaty, Andrew N Hoofnagle, David Siscovick, Sina A Gharib, Colleen M Sitlani, Nona Sotoodehnia, Rozenn N Lemaitre> ;ERJ Open Research. 2023 Mar 1
• 15 citations
  Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.
  Nick Shrine, Abril G Izquierdo, Jing Chen, Richard Packer, Robert J Hall, Anna L Guyatt, Chiara Batini, Rebecca J Thompson, Chandan Pavuluri, Vidhi Malik, Brian D Hobb...> ;Nature Genetics. 2023 Mar 1
• 7 citations
  Metabolomic Signatures Associated With Pulmonary Arterial Hypertension Outcomes.
  Hongyang Pi, Lu Xia, David D Ralph, Samuel G Rayner, Ali Shojaie, Peter J Leary, Sina A Gharib> ;Circulation Research. 2023 Feb 3
• 1 citations
  An integrated multi-omics analysis of sleep-disordered breathing traits implicates P2XR4 purinergic signaling.
  Nuzulul Kurniansyah, Danielle A Wallace, Ying Zhang, Bing Yu, Brian Cade, Heming Wang, Heather M Ochs-Balcom, Alexander P Reiner, Alberto R Ramos, Joshua D Smith, Jian...> ;Communications Biology. 2023 Jan 31
• 1 citations
  Nephronectin is required to maintain right lung lobar separation during embryonic development.
  Carole L Wilson, Chi F Hung, Brian M Burkel, Suzanne M Ponik, Sina A Gharib, Lynn M Schnapp> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2023 Mar 1
• 1 citations
  Rhinovirus infection of the airway epithelium enhances mast cell immune responses via epithelial-derived interferons.
  Ryan C Murphy, Ying Lai, Matthew C Altman, Kaitlyn A Barrow, Kimberly A Dill-McFarland, Matthew Liu, Jessica A Hamerman, Adam Lacy-Hulbert, Adrian M Piliponsky, Steven...> ;The Journal of Allergy and Clinical Immunology. 2023 Jun 1
• 5 citations
  Investigating associations of omega-3 fatty acids, lung function decline, and airway obstruction.
  Bonnie K Patchen, Palavi Balte, Traci M Bartz, R Graham Barr, Myriam Fornage, Mariaelisa Graff, David R Jacobs Jr, Ravi Kalhan, Rozenn N Lemaitre, George O'Connor, Bru...> ;Medrxiv. 2023 Jan 18
• 3 citations
  Concomitant western diet and chronic-binge alcohol dysregulate hepatic metabolism.
  Delfin Gerard Buyco, Joseph L Dempsey, Eleonora Scorletti, Sookyoung Jeon, Chelsea Lin, Julia Harkin, Susovon Bayen, Emma E Furth, Jasmin Martin, Monique Delima, Royce...> ;Plos One. 2023 Jan 1
• 3 citations
  Transpulmonary amino acid metabolism in the sugen hypoxia model of pulmonary hypertension.
  Nicolas Philip, Hongyang Pi, Mahin Gadkari, Xin Yun, John Huetsch, Cissy Zhang, Robert Harlan, Aurelie Roux, David Graham, Larissa Shimoda, Anne Le, Scott Visovatti, P...> ;Pulmonary Circulation. 2023 Jan 1
• 5 citations
  Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity.
  Pavan K Bhatraju, Eric D Morrell, Ian B Stanaway, Neha A Sathe, Avantika Srivastava, Radu Postelnicu, Richard Green, Adair Andrews, Martin Gonzalez, Christopher J Krat...> ;Critical Care Explorations. 2023 Jan 1
• 5 citations
  Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits.
  Sung Chun, Sebastian Akle, Athanasios Teodosiadis, Brian E Cade, Heming Wang, Tamar Sofer, Daniel S Evans, Katie L Stone, Sina A Gharib, Sutapa Mukherjee, Lyle J Palme...> ;Plos Genetics. 2022 Dec 1
• 4 citations
  Development and validation of a metabolite index for obstructive sleep apnea across race/ethnicities.
  Ying Zhang, Debby Ngo, Bing Yu, Neomi A Shah, Han Chen, Alberto R Ramos, Phyllis C Zee, Russell Tracy, Peter Durda, Robert Kaplan, Martha L Daviglus, Stephen S Rich, J...> ;Scientific Reports. 2022 Dec 16
• 83 citations
  Genetic diversity fuels gene discovery for tobacco and alcohol use.
  Gretchen R B Saunders, Xingyan Wang, Fang Chen, Seon-Kyeong Jang, Mengzhen Liu, Chen Wang, Shuang Gao, Yu Jiang, Chachrit Khunsriraksakul, Jacqueline M Otto, Clifton A...> ;Nature. 2022 Dec 1
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