
Sophie J Bakri MD
Retinal Disease
Professor & Chair of Ophthalmology, Mayo Clinic, Rochester MN
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- 200 1st St SWRochester, MN 55905 
- Phone+1 507-284-2511 
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Summary
- Clinical Expertise
 
 Dr. Sophie Bakri is a specialist in diseases and surgery of the retina and vitreous, in particular, age-related macular degeneration, diabetic retinopathy, venous occlusive disease, and repair of complex retinal detachments. She undertakes both clinical and translational research in the pathogenesis and treatment of retinal diseases.
 
 Research Focus areas
 -Clinical trials in retinal diseases focusing on pharmacotherapy for age-related macular degeneration, diabetic retinopathy, venous occlusive disease
 -Pharmacokinetics and tissue dynamics of intravitreal medications
 -Outcomes of pharmacotherapy in retinal disease
 
 Significance to patient care
 
 The goal of Dr. Bakri’s research is to understand how and why individuals differ in their response to medications to treat retinal disease. Through her work on drug pharmacokinetics and tissue dynamics, she is contributing to a better understanding of the effects of these drugs on tissues. This will help in understanding and mitigating drug side effects in patients, as well as selecting optimal drug delivery routes.
Education & Training
 Cleveland Clinic FoundationFellowship, Surgical Retina and Vitreous, 2003 - 2005 Cleveland Clinic FoundationFellowship, Surgical Retina and Vitreous, 2003 - 2005
 Albany Medical CenterResidency, Ophthalmology, 2000 - 2003 Albany Medical CenterResidency, Ophthalmology, 2000 - 2003
 University of Nottingham Medical SchoolClass of 1998 University of Nottingham Medical SchoolClass of 1998
Certifications & Licensure
 MN State Medical License 2005 - 2026 MN State Medical License 2005 - 2026
 OH State Medical License 2003 - 2005 OH State Medical License 2003 - 2005
 American Board of Ophthalmology Ophthalmology American Board of Ophthalmology Ophthalmology
Awards, Honors, & Recognition
- Senior Honor Award American Society of Retina Specialists
- Senior Honor Award American Academy of Ophthalmology
- Young Investigator Award American Society of Retina Specialists
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Clinical Trials
- Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD Start of enrollment: 2022 Jan 13
Publications & Presentations
PubMed
- Novel targets beyond vascular endothelial growth factor-A inhibition: improving vision with neovascular age-related macular degeneration treatment.Arshad M Khanani, Sophie J Bakri, Carl Regillo, Christina Y Weng, Tien Y Wong
 Eye. 2025-10-11
- Erratum to "An Analysis of Solicitations From Predatory Journals in Ophthalmology," Am J Ophthalmol 2024; 264:216-223.Grant A Justin, Charles Huang, Michael K Nguyen, Jessica Lee, Ian Seddon
 American Journal of Ophthalmology. 2025-09-01
- Corrigendum to "An Analysis of Solicitations From Predatory Journals in Ophthalmology," Am J Ophthalmol 2024; 264:216-223.Grant A Justin, Charles Huang, Michael K Nguyen, Jessica Lee, Ian Seddon
 American Journal of Ophthalmology. 2025-09-01
Press Mentions
 Early Steroid Switch May Improve Visual Acuity for Some DME PatientsOctober 11th, 2021 Early Steroid Switch May Improve Visual Acuity for Some DME PatientsOctober 11th, 2021
 ASRS Guidance on Managing COVID-19 Risk in Retinal ProceduresMarch 24th, 2020 ASRS Guidance on Managing COVID-19 Risk in Retinal ProceduresMarch 24th, 2020
 Ophthalmology Times® Announces Winners of 3rd Annual Research Scholar Honoree ProgramOctober 30th, 2019 Ophthalmology Times® Announces Winners of 3rd Annual Research Scholar Honoree ProgramOctober 30th, 2019
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Committees
- Organizer, AAO Retina Subspecialty Day 2021 - Present
Professional Memberships
- Fellow
- Member
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