StefanCostineanMD

PubMed

• 2 citations
  Author Correction: Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes.
  Norman L Lehman, Nathalie Spassky, Müge Sak, Amy Webb, Cory T Zumbar, Aisulu Usubalieva, Khaled J Alkhateeb, Joseph P McElroy, Kirsteen H Maclean, Paolo Fadda, Tom Liu...> ;Nature Communications. 2023 Jan 31
• 1 citations
  Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes.
  Norman L Lehman, Nathalie Spassky, Müge Sak, Amy Webb, Cory T Zumbar, Aisulu Usubalieva, Khaled J Alkhateeb, Joseph P McElroy, Kirsteen H Maclean, Paolo Fadda, Tom Liu...> ;Nature Communications. 2022 Apr 19
• 45 citations
  MicroRNA-29b mediates altered innate immune development in acute leukemia
  Bethany L. Mundy-Bosse, Steven D. Scoville, Li Chen, Kathleen McConnell, Hsiaoyin C. Mao, Elshafa H. Ahmed, Nicholas Zorko, Sophia Harvey, Jordan P. Cole, Xiaoli Zhang...> ;The Journal of Clinical Investigation. 2016 Dec 1
• 29 citations
  Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a
  Staci L. Haney, G. Michael Upchurch, Jana Opavska, David Klinkebiel, Ryan A. Hlady, Abhinav Suresh, Samuel J. Pirruccello, Vipul Shukla, Runqing Lu, Stefan Costinean, ...> ;Cell Reports. 2016 May 10
• 83 citations
  miR-15b/16-2 deletion promotes B-cell malignancies.
  Francesca Lovat, Matteo Fassan, Pierluigi Gasparini, Lara Rizzotto, Luciano Cascione, Marco Pizzi, Caterina Vicentini, Veronica Balatti, Dario Palmieri, Stefan Costine...> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 Sep 15
• 3 citations
  Gradual Rarefaction of Hematopoietic Precursors and Atrophy in a Depleted microRNA 29a, b and c Environment.
  Lauren Rachel Kauffman, Veronica Balatti, Luciano Cascione, Paolo Fadda, Frederick Racke, Ramasamy Santhanam, Stefan Costinean> ;Plos One. 2015 Jul 6
• 51 citations
  Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature
  Leah Cushing, Stefan Costinean, Wei Xu, Zhihua Jiang, Lindsey H. Madden, Ping-Ping Kuang, Jingshu Huang, Alexandra S. Weisman, Akiko Hata, Carlo M. Croce, Jining Lu> ;Plos Genetics. 2015 May 28
• 21 citations
  Regulated Expression of miR-155 is Required for iNKT Cell Development
  Alessia Burocchi, Paola Pittoni, Esmerina Tili, Alice Rigoni, Stefan Costinean, Carlo M. Croce, Mario P. Colombo> ;Frontiers in Immunology. 2015 Mar 30
• 125 citations
  MicroRNA 29 Targets Nuclear Factor-κB–Repressing Factor and Claudin 1 to Increase Intestinal Permeability
  QiQi Zhou, Stefan Costinean, Carlo M. Croce, Alan R. Brasier, Shehzad Merwat, Scott A. Larson, Sarpreet Basra, G. Nicholas Verne> ;Gastroenterology. 2015 Jan 1
• 87 citations
  Pluripotent Stem Cell miRNAs and Metastasis in Invasive Breast Cancer
  Stefano Volinia, Gerard J. Nuovo, Alessandra Drusco, Stefan Costinean, Ramzey Abujarour, Caroline Desponts, Michela Garofalo, Raffaele Baffa, Rami Aeqilan, Kati Maharr...> ;Journal of the National Cancer Institute. 2014 Dec 1
• 153 citations
  Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation
  Pierluigi Gasparini, Francesca Lovat, Matteo Fassan, Lucia Casadei, Luciano Cascione, Naduparambil K. Jacob, Stefania Carasi, Dario Palmieri, Stefan Costinean, Charles...> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Mar 25
• 25 citations
  Hepatic Loss of miR-122 Predisposes Mice to Hepatobiliary Cyst and Hepatocellular Carcinoma upon Diethylnitrosamine Exposure
  Shu-Hao Hsu, Bo Wang, Huban Kutay, Hemant K. Bid, Julia Shreve, Xiaoli Zhang, Stefan Costinean, Anna Bratasz, Peter J. Houghton, Kalpana Ghoshal> ;The American Journal of Pathology. 2013 Dec 1
• 50 citations
  Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells
  Rossana Trotta, Li Chen, Stefan Costinean, Srirama Josyula, Bethany L. Mundy-Bosse, David Ciarlariello, Charlene Mao, Edward L. Briercheck, Kathleen McConnell, Anjali ...> ;Blood. 2013 Apr 18
• 106 citations
  miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model.
  Sukhinder K. Sandhu, Stefano Volinia, Stefan Costinean, Marco Galasso, Reid Neinast, Ramasamy Santhanam, Mark R. Parthun, Danilo Perrotti, Guido Marcucci, Ramiro Garzo...> ;Proceedings of the National Academy of Sciences of the United States of America. 2012 Dec 4
• 7 citations
  Primary intrathyroidal paraganglioma: histopathology and novel molecular alterations
  Stefan Costinean, Veronica Balatti, Arianna Bottoni, M. Old, Carlo M. Croce, Paul E. Wakely> ;Human Pathology. 2012 Dec 1
• 47 citations
  Hepatic miR-29ab1 expression modulates chronic hepatic injury
  Takayuki Kogure, Stefan Costinean, Irene Yan, Chiara Braconi, Carlo M. Croce, Tushar Patel> ;Journal of Cellular and Molecular Medicine. 2012 Nov 1
• 144 citations
  miR-29ab1 Deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias That Is Dysregulated in Multiple Sclerosis
  Kristen Smith, Mireia Guerau-de-Arellano, Stefan Costinean, Jessica Williams, Arianna Bottoni, Gina Mavrikis Cox, Abhay R. Satoskar, Carlo M. Croce, Michael K. Racke, ...> ;Journal of Immunology. 2012 Aug 15
• 639 citations
  Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver
  Shu-Hao Hsu, Bo Wang, Janaiah Kota, Jianhua Yu, Stefan Costinean, Huban Kutay, Lianbo Yu, Shoumei Bai, Krista M. D. La Perle, Raghu R. Chivukula, Hsiaoyin Mao, Min Wei...> ;The Journal of Clinical Investigation. 2012 Aug 1
• 155 citations
  miR-155 regulates IFN-γ production in natural killer cells.
  Rossana Trotta, Li Chen, David Ciarlariello, Srirama Josyula, Charlene Mao, Stefan Costinean, Lianbo Yu, Jonathan P. Butchar, Susheela Tridandapani, Carlo M. Croce, Mi...> ;Blood. 2012 Apr 12
• 33 citations
  Stem cell-related markers in primary breast cancers and associated metastatic lesions
  Gulnur Guler, Serdar Balci, Stefan Costinean, Cigdem Himmetoglu Ussakli, Cigdem Irkkan, Dinc Suren, Ebru Sari, Kadri Altundag, Yavuz Ozisik, Susie Jones, Jason Bacher,...> ;Modern Pathology. 2012 Mar 2
• 40 citations
  Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies.
  Eugenio Gaudio, Riccardo Spizzo, Francesco Paduano, Zhenghua Luo, Alexey Efanov, Alexey Palamarchuk, Amanda S. Leber, Mohamed Kaou, Nicola Zanesi, Arianna Bottoni, Ste...> ;Blood. 2012 Jan 5
• 542 citations
  microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer.
  Chiara Braconi, Takayuki Kogure, Nicola Valeri, Nianyuan Huang, Gerard J. Nuovo, Stefan Costinean, Massimo Negrini, Elena Miotto, Carlo M. Croce, Tushar Patel> ;Oncogene. 2011 Nov 24
• 42 citations
  Aberrant expression of DNA damage response proteins is associated with breast cancer subtype and clinical features.
  Gulnur Guler, Cigdem Himmetoglu, Rafael E. Jimenez, Susan Geyer, Wenle P Wang, Stefan Costinean, Robert Pilarski, Carl Morrison, Dinc Suren, Jianhua Liu, Jingchun Chen...> ;Breast Cancer Research and Treatment. 2011 Sep 1
• 19 citations
  Common fragile site tumor suppressor genes and corresponding mouse models of cancer.
  Yuri Pekarsky, Stefan Costinean, Anna Antenucci, Laura Conti, Stefano Volinia, Rami I. Aqeilan, Kay Huebner, Nicola Zanesi, Alessandra Drusco> ;Journal of Biomedicine & Biotechnology. 2011 Jan 1
• 43 citations
  Loss of metallothionein predisposes mice to diethylnitrosamine-induced hepatocarcinogenesis by activating NF-kappaB target genes.
  Sarmila Majumder, Satavisha Roy, Thomas Kaffenberger, Bo Wang, Stefan Costinean, Wendy L. Frankel, Anna Bratasz, Periannan Kuppusamy, Tsonwin Hai, Kalpana Ghoshal, Sam...> ;Cancer Research. 2010 Dec 15
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