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3400 Civic Center Blvd# PerelmanPhiladelphia, PA 19104
Phone+1 215-662-4000
Fax+1 215-615-3704
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Summary
- Stephen J. Bagley, MD, MSCE, is an Assistant Professor of Medicine and Neurosurgery and Section Chief of Neuro-Oncology at the University of Pennsylvania Perelman School of Medicine. As a clinician-scientist, Dr. Bagley focuses both his research and clinical efforts on patients with primary brain and spinal cord tumors. He has particular expertise in translational immunotherapy trials for gliomas, as well as an interest in using blood and cerebrospinal fluid for less invasive molecular characterization and monitoring of brain tumors. Dr. Bagley has led retrospective studies, single institution prospective clinical trials, and multicenter prospective trials conducted nationally through the National Cancer Institute sponsored National Clinical Trials Network. In addition, he has chaired numerous Neuro-Oncology committees and workshops with international scope through the Society for Neuro-Oncology (SNO) and the American Society for Clinical Oncology (ASCO). Dr. Bagley earned his MD and MSCE degrees from Penn and completed both his internal medicine residency and hematology/oncology fellowship at the Hospital of the University of Pennsylvania.
Education & Training
University of Pennsylvania Health SystemFellowship, Hematology and Medical Oncology, 2014 - 2017- University of Pennsylvania Health SystemResidency, Internal Medicine, 2011 - 2014
Perelman School of Medicine at the University of PennsylvaniaClass of 2011
Certifications & Licensure
PA State Medical License 2011 - 2026
American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- Inductee Alpha Omega Alpha Honor Medical Society, 2011
Clinical Trials
- ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) Start of enrollment: 2023 Jan 23
- Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent Glioblastoma Start of enrollment: 2020 Jun 23
- CART-EGFR-IL13Ra2 in EGFR Amplified Recurrent GBM Start of enrollment: 2023 Feb 24
Publications & Presentations
PubMed
- Personalized machine learning-guided radiation dose escalation in newly diagnosed glioblastoma: prospective pilot study.Hamed Akbari, Suyash Mohan, Fang Liu, Cecilia Jiang, Anahita Fathi Kazerooni
Nature Communications. 2026-05-13 - Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival.Daniel J Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos
Annals of Clinical and Translational Neurology. 2026-05-05 - Clinical, molecular, and immunologic determinants of survival in WHO-defined IDH-wildtype glioblastoma treated with radiotherapy: a large real-world cohort study.Cole Friedes, Melanie Berger, Lauren Linkowski, Casey Hollawell, Harper Hubbeling
Journal of Neuro-Oncology. 2026-04-25
Journal Articles
- Thoracic Imaging of Non-Small Cell Lung Cancer Treated with Anti-Programmed Death Receptor-1 TherapyJoshua Bauml, Stephen Bagley, Charu Aggarwal, Corey Langer, ScienceDirect
- Perioperative Beta-blocker and Statin use in Patients with Coronary Artery Disease Undergoing Orthotopic Liver TransplantationBagley S, Grzybowski M, Litwack A, and Lilly S, Journal of Clinical Trials in Cardiology, 8/1/2014
Lectures
- Impact of antibiotics (ABX) on overall survival (OS) in patients (pts) with advanced non-small-cell lung cancer (aNSCLC) and melanoma (aMel) treated with first-line im...2019 ASCO Annual Meeting - 6/1/2019
- Comparative effectiveness of carboplatin-pemetrexed (Carbo-Pem) with vs. without bevacizumab (Bev) in patients with advanced non-squamous (Sq) non-small cell lung canc...2018 ASCO Annual Meeting - Chicago, Illinois - 06/3/2018
- Thinking Out of the Box: Novel Therapeutic Approaches2018 ASCO Annual Meeting - Chicago, Illinois - 06/2/2018
Press Mentions
How Future Cures Begin as Ideas in LaboratoriesJuly 10th, 2025- Key Takeaways from World’s Largest Cancer Conference in ChicagoJune 6th, 2025
- Bivalent CAR-T Cells via CSF Injection Show Activity in Recurrent GlioblastomaJune 2nd, 2025
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