StevenMCorselloMD

PubMed

• Proteomics-Based Discovery of First-in-Class Chemical Probes for Programmed Cell Death Protein 2 (PDCD2).
  Wenzhi Ji, Woong Sub Byun, Wenchao Lu, Xijun Zhu, Katherine A Donovan, Brendan G Dwyer, Jianwei Che, Linjie Yuan, Xianmixinuer Abulaiti, Steven M Corsello, Eric S Fisc...> ;Angewandte Chemie. 2023 Oct 23
• 4 citations
  Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors.
  Wenchao Lu, Mengyang Fan, Wenzhi Ji, Jason Tse, Inchul You, Scott B Ficarro, Isidoro Tavares, Jianwei Che, Audrey Y Kim, Xijun Zhu, Andrew Boghossian, Matthew G Rees, ...> ;Journal of Medicinal Chemistry. 2023 Apr 13
• 2 citations
  Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer.
  Rachel B Keller, Tali Mazor, Lynette Sholl, Andrew J Aguirre, Harshabad Singh, Nilay Sethi, Adam Bass, Ankur K Nagaraja, Lauren K Brais, Emma Hill, Connor Hennessey, M...> ;JCO Precision Oncology. 2023 Jan 1
• 6 citations
  Virtual screening for small-molecule pathway regulators by image-profile matching.
  Mohammad H Rohban, Ashley M Fuller, Ceryl Tan, Jonathan T Goldstein, Deepsing Syangtan, Amos Gutnick, Ann DeVine, Madhura P Nijsure, Megan Rigby, Joshua R Sacher, Stev...> ;Cell Systems. 2022 Sep 21
• 15 citations
  RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.
  Lishan Fang, Dane Ford-Roshon, Max Russo, Casey O'Brien, Xiaozhe Xiong, Carino Gurjao, Maximilien Grandclaudon, Srivatsan Raghavan, Steven M Corsello, Steven A Carr, N...> ;Nature Communications. 2022 Jun 8
• 184 citations
  The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K
  Mikolaj Slabicki, Zuzanna Kozicka, Georg Petzold, Yen-Der Li, Manisha Manojkumar, Richard D. Bunker, Katherine A. Donovan, Quinlan L. Sievers, Jonas Koeppel, Dakota Su...> ;Nature. 2020 Jun 3
• 321 citations
  Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling.
  Steven M. Corsello, Rohith T. Nagari, Ryan Spangler, Jordan Rossen, Mustafa Kocak, Jordan Bryan, Ranad Humeidi, David Peck, Xiaoyun Wu, Anna Tang, Vickie M. Wang, Sam ...> ;Nature Cancer. 2020 Jan 20
• 52 citations
  Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair Deficient Colorectal Cancer
  Carino Gurjao, David Liu, Matan Hofree, Saud H. AlDubayan, Isaac Wakiro, Mei-Ju Su, Kristen Felt, Evisa Gjini, Lauren K. Brais, Asaf Rotem, Michael H. Rosenthal, Orit ...> ;Cancer Immunology Research. 2019 Jan 1
• 1615 citations
  A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
  Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, David Peck, Ted Natoli, Xiaodong Lu, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. ...> ;Cell. 2017 Nov 30
• 471 citations
  The Drug Repurposing Hub: a next-generation drug library and information resource
  Steven M. Corsello, Joshua A. Bittker, Zihan Liu, Joshua Gould, Patrick McCarren, Jodi E. Hirschman, Stephen Johnston, Anita Vrcic, Bang Wong, Mariya Khan, Jacob K. As...> ;Nature Medicine. 2017 Apr 7
• 38 citations
  Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study.
  Arezou A. Ghazani, Nelly Oliver, Joseph P. St. Pierre, Andrea Garofalo, Irene Rainville, Elaine Hiller, Daniel J. Treacy, Vanesa Rojas-Rudilla, Sam Wood, Elizabeth Bai...> ;Genetics in Medicine. 2017 Jan 26
• 116 citations
  Systematic functional interrogation of rare cancer variants identifies oncogenic alleles
  Eejung Kim, Nina Ilic, Yashaswi Shrestha, Lihua Zou, Atanas Kamburov, Cong Zhu, Xiaoping Yang, Rakela Lubonja, Nancy Tran, Cindy Nguyen, Michael S. Lawrence, Federica ...> ;Cancer Discovery. 2016 Jul 1
• 129 citations
  A functional landscape of resistance to ALK inhibition in lung cancer.
  Frederick H. Wilson, Cory M. Johannessen, Federica Piccioni, Pablo Tamayo, Jong Wook Kim, Eliezer M. Van Allen, Steven M. Corsello, Marzia Capelletti, Antonio Calles, ...> ;Cancer Cell. 2015 Mar 9
• 33 citations
  Identification of AML1-ETO modulators by chemical genomics.
  Steven M. Corsello, Giovanni Roti, Kenneth N. Ross, Kwan T. Chow, Ilene Galinsky, Daniel J. DeAngelo, Richard Stone, Andrew L. Kung, Todd R. Golub, Kimberly Stegmaier> ;Blood. 2009 Jun 11
• 1 citations
  Does androgen deprivation therapy in men with prostate cancer increase cardiovascular morbidity
  Steven M. Corsello, Philip W. Kantoff> ;Nature Clinical Practice. Urology. 2008 Feb 1
• 91 citations
  Gefitinib induces myeloid differentiation of acute myeloid leukemia.
  Kimberly Stegmaier, Steven M. Corsello, Kenneth N. Ross, Jenny S. Wong, Daniel J. DeAngelo, Todd R. Golub> ;Blood. 2005 Oct 15
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