StevenR.GrossmanMD

PubMed

• 2 citations
  Evidence for a causal link between intra-pancreatic fat deposition and pancreatic cancer: A prospective cohort and Mendelian randomization study.
  Yamazaki, H., Streicher, S., Wu, L., Fukuhara, S., Wagner, R., Heni, M., Setiawan, V., Le Marchand, L., Huang, B., Grossman, S., Lenz, H.> ;Cell Reports. Medicine. 2024 Feb 20
• Proteasome inhibition paradoxically degrades gain-of-function mutant p53 R273H in NSCLC and could have therapeutic implications.
  Susan T Sharfstein, Larisa Litovchick, Eziafa I Oduah, Nagashree Seetharamu, Steven R Grossman> ;Frontiers in Oncology. 2024 Jan 1
• Coordinate transcriptional regulation of ErbB2/3 by C-terminal binding protein 2 signals sensitivity to ErbB2 inhibition in pancreatic adenocarcinoma.
  Kranthi Kumar Chougoni, Haemin Park, Priyadarshan K Damle, Travis Mason, Bo Cheng, Martin M Dcona, Barbara Szomju, Mikhail G Dozmorov, Michael O Idowu, Steven R Grossman> ;Oncogenesis. 2023 Nov 10
• Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer.
  M Michael Dcona, Kranthi Kumar Chougoni, Diana T Dcona, Jacqueline L West, Sahib J Singh, Keith C Ellis, Steven R Grossman> ;Cancer Research Communications. 2023 Oct 4
• 1 citations
  ADCC's Improving Goal Concordant Care Initiative: Implementing Primary Palliative Care Principles.
  Elizabeth T Loggers, Amy A Case, Marcin Chwistek, William Dale, Marvin O Delgado Guay, Stephen B Edge, Steven R Grossman, Jillian Gustin, Judith Nelson, Sahana Rajasek...> ;Journal of Pain and Symptom Management. 2023 Aug 1
• Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis.
  Tiantian Zhang, Sha Li, Yingcai Adrian Tan, Joseph HyungJoon Na, Zhengming Chen, Priyadarshan Damle, Xiang Chen, Soyoung Choi, Bikash Mishra, Dunrui Wang, Steven R Gro...> ;Biorxiv. 2023 Apr 28
• 12 citations
  Rising Incidence and Racial Disparities of Early-Onset Pancreatic Cancer in the United States, 1995-2018.
  Brian Z Huang, Lihua Liu, Juanjuan Zhang, , Stephen J Pandol, Steven R Grossman, Veronica Wendy Setiawan> ;Gastroenterology. 2022 Jul 1
• 4 citations
  Flower lose, a cell fitness marker, predicts COVID-19 prognosis.
  Michail Yekelchyk, Esha Madan, Jochen Wilhelm, Kirsty R. Short, António M Palma, Linbu Liao, Denise Camacho, Everlyne Nkadori, Michael T. Winters, Emily S Rice, Inês R...> ;EMBO Molecular Medicine. 2021 Nov 8
• 37 citations
  Cell competition in intratumoral and tumor microenvironment interactions.
  Taylor M Parker, Kartik Gupta, António M Palma, Michail Yekelchyk, Paul B. Fisher, Steven R Grossman, Kyoung-Jae Won, Esha Madan, Eduardo Moreno, Rajan Gogna> ;The EMBO Journal. 2021 Sep 1
• 9 citations
  Clinical Activity and Safety of Cediranib and Olaparib Combination in Patients with Metastatic Pancreatic Ductal Adenocarcinoma without BRCA Mutation.
  Joseph Kim, Dana Backlund Cardin, Ulka N. Vaishampayan, Shumei Kato, Steven R. Grossman, Peter M. Glazer, Yu Shyr, S. Percy Ivy, Patricia LoRusso> ;The Oncologist. 2021 Jul 1
• 11 citations
  Cryo-EM structure of CtBP2 confirms tetrameric architecture.
  Anne M. Jecrois, M. Michael Dcona, Xiaoyan Deng, Dipankar Bandyopadhyay, Steven R. Grossman, Celia A. Schiffer, William E. Royer> ;Structure. 2021 Apr 1
• 13 citations
  The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3
  Catherine A. Vaughan, Shilpa Singh, Mark A. Subler, Jolene J. Windle, Kazushi Inoue, Elizabeth A. Fry, Raghavendra Pillappa, Steven R. Grossman, Brad Windle, W. Andrew...> ;Nature Communications. 2021 Jan 29
• 11 citations
  CtBP determines ovarian cancer cell fate through repression of death receptors.
  Boxiao Ding, Fang Yuan, Priyadarshan K. Damle, Larisa Litovchick, Ronny Drapkin, Steven R. Grossman> ;Cell Death & Disease. 2020 Apr 24
• 9 citations
  Harnessing the vulnerabilities of p53 mutants in lung cancer - Focusing on the proteasome: a new trick for an old foe?
  Eziafa I Oduah, Steven R. Grossman> ;Cancer Biology & Therapy. 2020 Feb 10
• 3 citations
  Extraction of high-quality RNA from mouse pancreatic tumors.
  Kranthi Kumar Chougoni, Steven R. Grossman> ;Methodsx. 2020 Jan 1
• 12 citations
  p53-inducible SESTRINs might play opposite roles in the regulation of early and late stages of lung carcinogenesis.
  Boxiao Ding, Alexander Haidurov, Ayesha Chawla, Anita Parmigiani, Gerarda van de Kamp, Alexandra A. Dalina, Fang Yuan, Jun Hee Lee, Peter M. Chumakov, Steven R. Grossm...> ;Oncotarget. 2019 Dec 10
• 14 citations
  CtBP-a targetable dependency for tumor-initiating cell activity and metastasis in pancreatic adenocarcinoma.
  Ayesha Chawla, Kranthi Kumar Chougoni, Prashant J. Joshi, Agnes D Cororaton, Patrick Memari, John C. Stansfield, Haemin Park, Rashmi Seth, Barbara Szomju, Adam Sima, M...> ;Oncogenesis. 2019 Oct 4
• 2 citations
  Phase 1 Study of Neoadjuvant Short-Course Radiation Therapy Concurrent With Infusional 5-Fluorouracil for the Treatment of Locally Advanced Rectal Cancer.
  Emma C. Fields, Brian J. Kaplan, Jeremy Karlin, Jennifer Myers, Nitai D. Mukhopadhyay, Xiaoyan Deng, Heidi Sankala, Steven R. Grossman, Khalid Matin> ;Advances in Radiation Oncology. 2019 May 11
• 12 citations
  DBC1 Regulates p53 Stability via Inhibition of CBP-Dependent p53 Polyubiquitination
  Oluwatoyin Akande, Priyadarshan K. Damle, Marius S. Pop, Nicholas E. Sherman, Barbara Szomju, Larisa Litovchick, Steven R. Grossman> ;Cell Reports. 2019 Mar 19
• 6 citations
  Active-Site Tryptophan, the Target of Antineoplastic C-Terminal Binding Protein Inhibitors, Mediates Inhibitor Disruption of CtBP Oligomerization and Transcription Cor...
  M. Michael Dcona, Priyadarshan K Damle, Francisco Zarate-Perez, Benjamin L. Morris, Zaid Nawaz, Michael J Dennis, Xiaoyan Deng, Sudha Korwar, Sahib J. Singh, Keith C E...> ;Molecular Pharmacology. 2019 Jan 1
• 6 citations
  An intestinal stem cell niche in Apc mutated neoplasia targetable by CtBP inhibition
  Ayesha Chawla, Agnes D Cororaton, Michael O. Idowu, Priyadarshan K. Damle, Barbara Szomju, Keith C. Ellis, Bhaumik B. Patel, Steven R. Grossman> ;Oncotarget. 2018 Aug 21
• 22 citations
  Classification of gastrointestinal stromal tumor syndromes.
  Priya Gopie, Lin Mei, Anthony C. Faber, Steven R. Grossman, Steven C. Smith, Sosipatros A. Boikos> ;Endocrine-Related Cancer. 2018 Feb 1
• 53 citations
  CtBP- an emerging oncogene and novel small molecule drug target: Advances in the understanding of its oncogenic action and identification of therapeutic inhibitors.
  M. Michael Dcona, Benjamin L. Morris, Keith C. Ellis, Steven R. Grossman> ;Cancer Biology & Therapy. 2017 Jun 14
• 27 citations
  Mutant p53 establishes targetable tumor dependency by promoting unscheduled replication
  Shilpa Singh, Catherine A. Vaughan, Rebecca Frum, Steven R. Grossman, Sumitra Deb, Swati Palit Deb> ;The Journal of Clinical Investigation. 2017 May 1
• 13 citations
  Gain-of-function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cells.
  Catherine A. Vaughan, Shilpa Singh, Steven R. Grossman, Brad Windle, Swati Palit Deb, Sumitra Deb> ;Molecular Oncology. 2017 Jun 1
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