StuartFeinsteinMD

PubMed

• 15 citations
  Differential Morphological and Biochemical Recovery from Chemotherapy-Induced Peripheral Neuropathy Following Paclitaxel, Ixabepilone, or Eribulin Treatment in Mouse S...
  Brett M. Cook, Krystyna M. Wozniak, Duncan A. Proctor, R. B. Bromberg, Ying Wu, Barbara S. Slusher, Bruce A. Littlefield, Mary Ann Jordan, Leslie Wilson, Stuart C. Fei...> ;Neurotoxicity Research. 2018 Jul 26
• 51 citations
  Peripheral Neuropathy Induced by Microtubule-Targeted Chemotherapies: Insights into Acute Injury and Long-term Recovery.
  Krystyna M. Wozniak, James J. Vornov, Ying Wu, Ying Liu, Valentina Alda Carozzi, Virginia Rodriguez-Menendez, Elisa Ballarini, Paola Alberti, Eleonora Pozzi, S. Semper...> ;Cancer Research. 2017 Jan 1
• 10 citations
  Paclitaxel suppresses Tau-mediated microtubule bundling in a concentration-dependent manner
  Myung Chul Choi, Peter J. Chung, Chaeyeon Song, Herbert P. Miller, Erkan Kiris, Youli Li, Leslie Wilson, Stuart C. Feinstein, Cyrus R. Safinya> ;Biochimica Et Biophysica Acta. General Subjects. 2017 Jan 1
• 18 citations
  Opposing Effects of Cucurbit[7]uril and 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranose on Amyloid β25-35 Assembly.
  Natália E. C. de Almeida, Thanh D. Do, Michael Tro, Nichole E. LaPointe, Stuart C. Feinstein, Joan-Emma Shea, Michael T. Bowers> ;ACS Chemical Neuroscience. 2016 Feb 17
• 34 citations
  Direct force measurements reveal that protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules.
  Peter J. Chung, Myung Chul Choi, Herbert P. Miller, H. Eric Feinstein, Uri Raviv, Youli Li, Leslie Wilson, Stuart C. Feinstein, Cyrus R. Safinya> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 Nov 24
• 25 citations
  Tau Aggregation Propensity Engrained in Its Solution State.
  Neil A. Eschmann, Thanh D. Do, Nichole E. LaPointe, Joan-Emma Shea, Stuart C. Feinstein, Michael T. Bowers, Songi Han> ;The Journal of Physical Chemistry. B. 2015 Oct 28
• 113 citations
  Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3.
  Pritam Ganguly, Thanh D. Do, Luca Larini, Nichole E. LaPointe, Alexander J. Sercel, Madeleine F. Shade, Stuart C. Feinstein, Michael T. Bowers, Joan-Emma Shea> ;The Journal of Physical Chemistry. B. 2015 Mar 24
• 132 citations
  Regulation and aggregation of intrinsically disordered peptides.
  Zachary A. Levine, Luca Larini, Nichole E. LaPointe, Stuart C. Feinstein, Joan-Emma Shea> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 Mar 3
• 23 citations
  Factors That Drive Peptide Assembly from Native to Amyloid Structures: Experimental and Theoretical Analysis of [Leu-5]-Enkephalin Mutants
  Thanh D. Do, Nichole E. LaPointe, Smriti Sangwan, David B. Teplow, Stuart C. Feinstein, Michael R. Sawaya, David Eisenberg, Michael T. Bowers> ;The Journal of Physical Chemistry. B. 2014 Jun 18
• 10 citations
  Tau proteins harboring neurodegeneration-linked mutations impair kinesin translocation in vitro.
  Dezhi Yu, Nichole E. LaPointe, Elmer Guzman, Veronica Pessino, Leslie Wilson, Stuart C. Feinstein, Megan T. Valentine> ;Journal of Alzheimer's Disease. 2014 Jan 1
• 20 citations
  A novel MAPT mutation, G55R, in a frontotemporal dementia patient leads to altered Tau function.
  Abhinaya Iyer, Nichole E. LaPointe, Krzysztof Zielke, Mariusz Berdyński, Elmer Guzman, Anna Barczak, Małgorzata Chodakowska-Żebrowska, Maria Barcikowska, Stuart C. Fei...> ;Plos One. 2013 Sep 27
• 27 citations
  Effects of pH and charge state on peptide assembly: the YVIFL model system.
  Thanh D. Do, Nichole E. LaPointe, Nicholas J. Economou, Steven K. Buratto, Stuart C. Feinstein, Joan-Emma Shea, Michael T. Bowers> ;The Journal of Physical Chemistry. B. 2013 Sep 4
• 20 citations
  Factors That Drive Peptide Assembly and Fibril Formation: Experimental and Theoretical Analysis of Sup35 NNQQNY Mutants
  Thanh D. Do, Nicholas J. Economou, Nichole E. LaPointe, William M. Kincannon, Christian Bleiholder, Stuart C. Feinstein, David B. Teplow, Steven K. Buratto, Michael T....> ;The Journal of Physical Chemistry. B. 2013 Jul 9
• 150 citations
  Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced p...
  Nichole E. LaPointe, Gerardo Morfini, Scott T. Brady, Stuart C. Feinstein, Leslie Wilson, Mary Ann Jordan> ;Neurotoxicology. 2013 Jul 1
• 43 citations
  Initiation of assembly of tau(273-284) and its ΔK280 mutant: an experimental and computational study
  Luca Larini, Megan Murray Gessel, Nichole E. LaPointe, Thanh D. Do, Michael T. Bowers, Stuart C. Feinstein, Joan-Emma Shea> ;Physical Chemistry Chemical Physics. 2013 May 22
• 69 citations
  Amyloid β-Mediated Cell Death of Cultured Hippocampal Neurons Reveals Extensive Tau Fragmentation without Increased Full-length Tau Phosphorylation
  Jack Reifert, DeeAnn Hartung-Cranston, Stuart C. Feinstein> ;The Journal of Biological Chemistry. 2011 Jun 10
• 9 citations
  Nanoscale assembly in biological systems: from neuronal cytoskeletal proteins to curvature stabilizing lipids.
  Cyrus R. Safinya, Uri Raviv, Daniel J. Needleman, Alexandra Zidovska, Myung Chul Choi, Miguel A. Ojeda-Lopez, Kai K. Ewert, Youli Li, Herbert P. Miller, Joel Quispe, B...> ;Advanced Materials. 2011 May 24
• 29 citations
  Combinatorial Tau Pseudophosphorylation: MARKEDLY DIFFERENT REGULATORY EFFECTS ON MICROTUBULE ASSEMBLY AND DYNAMIC INSTABILITY THAN THE SUM OF THE INDIVIDUAL PARTS
  Erkan Kiris, Donovan Ventimiglia, M.E. Sargin, Michelle R. Gaylord, Alphan Altinok, Kenneth Rose, B.S. Manjunath, Mary Ann Jordan, Leslie Wilson, Stuart C. Feinstein> ;The Journal of Biological Chemistry. 2011 Apr 22
• 25 citations
  Tau isoform-specific modulation of kinesin-driven microtubule gliding rates and trajectories as determined with tau-stabilized microtubules.
  Austin Peck, M. Emre Sargin, Nichole E. LaPointe, Kenneth Rose, B.S. Manjunath, Stuart C. Feinstein, Leslie Wilson> ;Cytoskeleton. 2011 Jan 1
• 22 citations
  The Neuroprotective Peptide NAP Does Not Directly Affect Polymerization or Dynamics of Reconstituted Neural Microtubules
  Mythili Yenjerla, Nichole E. LaPointe, Manu Lopus, Corey Cox, Mary Ann Jordan, Stuart C. Feinstein, Leslie Wilson> ;Journal of Alzheimer's Disease. 2010 Jan 1
• 21 citations
  Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of β-tubulin at Cys 12 and suppression of microtubule dynamics
  Wanhong Xu, Biao Xi, Jieying Wu, Haoyun An, Jenny Zhu, Yama A. Abassi, Stuart C. Feinstein, Michelle R. Gaylord, Baoqin Geng, Huifang Yan, Weimin Fan, Meihua Sui, Xiao...> ;Molecular Cancer Therapeutics. 2009 Dec 1
• 199 citations
  Kinetic Cell-Based Morphological Screening: Prediction of Mechanism of Compound Action and Off-Target Effects
  Yama A. Abassi, Biao Xi, Wenfu Zhang, Peifang Ye, Shelli L. Kirstein, Michelle R. Gaylord, Stuart C. Feinstein, Xiaobo Wang, Xiao Xu> ;Chemistry & Biology. 2009 Jul 31
• 59 citations
  Human Microtubule-Associated-Protein Tau Regulates the Number of Protofilaments in Microtubules: A Synchrotron X-Ray Scattering Study
  Myung Chul Choi, Uri Raviv, Herbert P. Miller, Michelle R. Gaylord, Erkan Kiris, Donovan Ventimiglia, Daniel J. Needleman, Mahn Won Kim, Leslie Wilson, Stuart C. Feins...> ;Biophysical Journal. 2009 Jul 22
• 35 citations
  FTDP-17 mutations in Tau alter the regulation of microtubule dynamics: an "alternative core" model for normal and pathological Tau action.
  Adria C LeBoeuf, Sasha F. Levy, Michelle R. Gaylord, Arnab Bhattacharya, Ambuj K. Singh, Mary Ann Jordan, Leslie Wilson, Stuart C. Feinstein> ;The Journal of Biological Chemistry. 2008 Dec 26
• 1 citations
  A general modeling and visualization tool for comparing different members of a group: application to studying tau-mediated regulation of microtubule dynamics.
  Arnab Bhattacharya, Sasha F. Levy, Adria C LeBoeuf, Michelle R. Gaylord, Leslie Wilson, Ambuj K. Singh, Stuart C. Feinstein> ;BMC Bioinformatics. 2008 Aug 12
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