Stuart Jon Spechler MD
Esophagus Disease
Chief, Division of Gastroenterology Co-Director, Center for Esophageal Diseases Baylor University Medical Center at Dallas Co-Director, Center for Esophageal Research Baylor Scott & White Research Institute
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3434 Swiss AveSte 200Dallas, TX 75204
Phone+1 469-800-7050
Fax+1 469-800-7060
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Summary
- Dr. Stuart Spechler is a gastroenterologist based in Dallas, TX, specializing in esophageal disease. He graduated from Boston University School of Medicine in 1974 and completed both his residency and fellowship at the Boston VA Healthcare System. Currently, he serves as the Chief of the Division of Gastroenterology at Baylor University Medical Center. Dr. Spechler has expertise in general gastroenterology, gastroesophageal reflux, pancreatic cancer, and esophageal disease. He has authored multiple publications on esophageal conditions and has been involved in clinical trials focusing on reflux esophagitis, GERD, Barrett's Esophagus, and eosinophilic esophagitis. He is recognized as a Fellow by both the American Gastroenterological Association and the American College of Gastroenterology. In 2026, Dr. Spechler became president of the American Foregut Society, and he received the William Beaumont Prize in Gastroenterology from the American Gastroenterological Association, a prize that honors a senior investigator who has made a major contribution that has significantly advanced care of patients with digestive diseases through clinical or translational research.
Education & Training
Boston VA Healthcare System (Brockton-West Roxbury)Fellowship, Gastroenterology, 1977 - 1979- Boston VA Healthcare System (Brockton-West Roxbury)Residency, Internal Medicine, 1974 - 1977
Boston University School of MedicineClass of 1974
Certifications & Licensure
MA State Medical License 1976 - 2027
TX State Medical License 1999 - 2027
American Board of Internal Medicine Internal Medicine- American Board of Internal Medicine Gastroenterology
Awards, Honors, & Recognition
- Named President American Foregut Society, 2026
- William Beaumont Prize in Gastroenterology American Gastroenterological Association, 2026
- Fellow (AGAF) American Gastroenterological Association, 2006
Clinical Trials
- Clinical Studies on Bile Acids in Barrett's Esophagus
- A Randomized Trial of Medical and Surgical Treatments for Patients With GERD Symptoms That Are Refractory to Proton Pump Inhibitors Start of enrollment: 2012 Aug 13
- The Frequency of Eosinophilic Esophagitis in Patients With Heartburn That is Refractory to Proton Pump Inhibitors
Publications & Presentations
PubMed
- Beyond the Surface: Exploring Altered Esophageal Distensibility and Compliance in Eosinophilic Esophagitis.Chanakyaram A Reddy, Melissa Nelson, Rhonda F Souza, Stuart J Spechler, Anh D Nguyen
Digestive Diseases and Sciences. 2026-09-23 - 1 citationsAchalasia and Risk of Esophageal Squamous Cell Carcinoma and Adenocarcinoma in a Multinational Study.Wilhelm Leijonmarck, Giola Santoni, Dag Holmberg, Stuart Spechler, My von Euler-Chelpin
Gastroenterology. 2026-09-01 - Discordance Between Functional Lumen Imaging Probe and Timed Barium Esophagram in Patients With a Chicago Classification v4.0 Manometric Diagnosis of Esophagogastric J...Roma N Ahuja, Mehr Hakim, Ashton C Ellison, Chanakyaram A Reddy, Vani J A Konda
Neurogastroenterology and Motility. 2026-09-01
Journal Articles
- Can Eosinophilic Esophagitis Cause Achalasia and Other Esophageal Motility Disorders?Stuart Jon Spechler, Rhonda Souza, Nature
Lectures
- Contemporary Review of PPI Therapy: What You and Your Patients Need to KnowAGC 2018 Annual Scientific Meeting, Philadelphia, PA - 10/5/2018
- Proton Pump Inhibitors: What the Internist Needs to KnowAmerican Gastroenterological Association (AGA) Institute, San Diego, California - 5/19/2012
Other
- Proton Pump Inhibitors: What the Internist Needs to KnowStuart Spechler, MD, ScienceDirect
https://www.doximity.com/articles/8ad152a3-26a9-43e1-8598-a6a7b947fedd
UpToDate, Wolters Kluwer Health - 2013-04-17 - Proton Pump Inhibitors: What the Internist Needs to KnowStuart Spechler, MD, ScienceDirect
https://www.doximity.com/articles/8ad152a3-26a9-43e1-8598-a6a7b947fedd
UpToDate, Wolters Kluwer Health - 2012-12-18 - Proton Pump Inhibitors: What the Internist Needs to KnowStuart Spechler, MD, ScienceDirect
https://www.doximity.com/articles/8ad152a3-26a9-43e1-8598-a6a7b947fedd
UpToDate, Wolters Kluwer Health - 2012-04-27
Press Mentions
AGA Clinical Practice Update Says P-cABs Can Help When Patients Fail PPI TherapyJanuary 10th, 2025- Phathom Pharmaceuticals Presents Data on Novel Potassium-Competitive Acid Blocker (PCAB) Vonoprazan from a Range of Studies at Digestive Disease Week® (DDW) 2022May 24th, 2022
Surgery Helps Tough-to-Treat Acid RefluxJanuary 11th, 2020
Grant Support
- Stratification of Cancer Risk in Patients with Non-Dysplastic Barrett's Esophagus using TissueCypher: The SCRiBE studyBAYLOR RESEARCH INSTITUTE2023–2027
- The Role of APE1/Ref-1 in Reflux-Induced Epithelial-Mesenchymal Transition in Benign Barrett's Metaplasia: A Novel Target for Preventing Recurrent Barrett's Esophagus After Radiofrequency AblationBAYLOR RESEARCH INSTITUTE2020–2025
- Clinical Studies On Bile Acids In Barrett'S EsophagusVeterans Affairs2011–2012
- Basic And Clinical Studies On The Role Of Bile Acids In Barrett'S EsophagusNational Cancer Institute2009–2012
- Clinical Studies On Bile Acids In Barrett'S EsophagusClinical Science Research &Development2009
Professional Memberships
- Fellow
- Fellow
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