SuhaylSamihDhib-JalbutMD

Neurology • New Brunswick, NJ

Neuroimmunology/Multiple Sclerosis

Professor and Chairman, Department of Neurology, Rutgers-RWJ Medical School and New Jersey Medical School

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Office
125 Paterson Street
CAB 6200
New Brunswick, NJ 08901
Phone+1 732-235-7335

Fax+1 732-235-8115
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Education & Training

University of Cincinnati Medical Center/College of MedicineResidency, Neurology, 1981 - 1985
American University of BeirutB.S., 1976 - 1980
American University of Beirut Faculty of MedicineClass of 1980

Certifications & Licensure

NJ State Medical License 2003 - 2025
MD State Medical License 1986 - 2008
OH State Medical License 1984 - 1992
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

Edward J. Ill Excellence in Medicine Award for Outstanding Medical Research Scientist 2013
Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2011
Medical Excellence Award The National Multiple Sclerosis Society-NJ Metro Chapter, 2009
The Norman Edelman Clinical Science Mentoring Award for 2008 UMDNJ-Robert Wood Johnson Medical School, 2009
Best Doctors in America 2009
Chair of the Scientific Program Committee World Congress on Multiple Sclerosis, 2008
Board of Trustees member The NJ Metro Chapter of the National Multiple Sclerosis Society, 2006
Co-Chair program committee Congress of the combined Americas and European Committees for Treatment and Research in Multiple Sclerosis, 2002
Mid-career Investigator Award (K-24) National Institute of Neurological Disorders and Stroke (NINDS), 1999
Mid-career Investigator Award (K-24) National Institutes of Health (NIH), 1999
Fellow American Academy of Neurology, 1998
Research Training Award University of Maryland School of Medicine, 1994
VA Career Development Award (Research Associate) 1992
The Muscular Dystrophy Association Fellowship Award University of Cincinnati Medical Center, 1984
Alpha Omega Alpha (A.O.A.) Honor Medical Society 1980
The Richard Jebara Medical Grant American University of Beirut, 1979
The Annual Munib Shahid Medical Award American University of Beirut, 1979
Dean's Honor List American University of Beirut, 1976
Whos Who in Medicine and Healthcare Marquis Whos Who
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Clinical Trials

A Combination Trial of Copaxone Plus Estriol in Relapsing Remitting Multiple Sclerosis (RRMS) Start of enrollment: 2007 Mar 01
Completed
Phase 2

Publications & Presentations

PubMed

1 citations
Interaction of the Gut Microbiome and Immunity in Multiple Sclerosis: Impact of Diet and Immune Therapy.
Sudhir Kumar Yadav, Kouichi Ito, Suhayl Dhib-Jalbut> ;International Journal of Molecular Sciences. 2023 Sep 29
2 citations
Monthly triple-dose gadolinium administration: potential associations with leukopenia, hypophosphatemia, and bone marrow T1 hyperintensity.
Daniel Chen, Ivan Wolansky, Jaime Imitola, Carl Malchoff, Rong Wu, Suhayl Dhib-Jalbut, Ketan Bulsara, Leo Wolansky> ;The Journal of International Medical Research. 2022 Feb 1
9 citations
Fecal Lcn-2 level is a sensitive biological indicator for gut dysbiosis and intestinal inflammation in multiple sclerosis.
Sudhir K Yadav, Naoko Ito, John E Mindur, Hetal Kumar, Mysra Youssef, Shradha Suresh, Ratuja Kulkarni, Yaritza Rosario, Konstantin E Balashov, Suhayl Dhib-Jalbut, Koui...> ;Frontiers in Immunology. 2022 Jan 1
1 citations
Effect of switching glatiramer acetate formulation from 20 mg daily to 40 mg three times weekly on immune function in multiple sclerosis.
Kouichi Ito, Naoko Ito, Sudhir K. Yadav, Shradha Suresh, Yong Lin, Suhayl Dhib-Jalbut> ;Multiple Sclerosis Journal - Experimental, Translational and Clinical. 2021 Jul 28
10 citations
Dimethyl Fumarate Suppresses Demyelination and Axonal Loss through Reduction in Pro-Inflammatory Macrophage-Induced Reactive Astrocytes and Complement C3 Deposition.
Sudhir K. Yadav, Naoko Ito, Kouichi Ito, Suhayl Dhib-Jalbut> ;Journal of Clinical Medicine. 2021 Feb 19
11 citations
Potential Risks and Benefits of Multiple Sclerosis Immune Therapies in the COVID-19 Era: Clinical and Immunological Perspectives.
Vikram Bhise, Suhayl Dhib-Jalbut> ;Neurotherapeutics. 2021 Feb 2
5 citations
MRI demonstration of gadolinium deposition in bone after monthly triple-dose gadopentetate dimeglumine and correlation with frequency of hypophosphatemia
John J. Debevits, Reshma Munbodh, Joshua Kaplan, Rong Wu, Paul A. Dicamillo, Chaoran Hu, Yanlin Wang, David Karimeddini, Robert T. Naismith, Suhayl Dhib-Jalbut, Leo J....> ;Clinical Imaging. 2021 Feb 1
7 citations
Surface Layer Protein A Expressed in Clostridioides difficile DJNS06-36 Possesses an Encephalitogenic Mimotope of Myelin Basic Protein.
John E. Mindur, Sudhir K. Yadav, Naoko Ito, Mitsutoshi Senoh, Haru Kato, Suhayl Dhib-Jalbut, Kouichi Ito> ;Microorganisms. 2020 Dec 24
7 citations
Gray Matter Nucleus Hyperintensity After Monthly Triple-Dose Gadopentetate Dimeglumine With Long-term Magnetic Resonance Imaging.
John J. Debevits, Reshma Munbodh, Rong Wu, Paul A. Dicamillo, Chaoran Hu, Lihong Wang, Robert T. Naismith, David Karimeddini, Suhayl Dhib-Jalbut, Sviatoslav Redko, Stu...> ;Investigative Radiology. 2020 Oct 1
3 citations
Fibrinolysis induced clinical improvement in a patient with multiple sclerosis exacerbation.
Konstantin E. Balashov, Suhayl Dhib-Jalbut, Igor Rybinnik> ;Multiple Sclerosis and Related Disorders. 2020 Aug 1
44 citations
Insight into the mechanism of action of dimethyl fumarate in multiple sclerosis.
Sudhir K. Yadav, Kouichi Ito, Suhayl Dhib-Jalbut> ;Journal of Molecular Medicine. 2019 Feb 28
42 citations
Gut dysbiosis breaks immunological tolerance toward the central nervous system during young adulthood
Sudhir K. Yadav, Sridhar Boppana, Naoko Ito, John E. Mindur, Martin T. Mathay, Ankoor Patel, Suhayl Dhib-Jalbut, Kouichi Ito> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 Oct 31
11 citations
IL-27: a potential biomarker for responders to glatiramer acetate therapy
John E. Mindur, Reuben M. Valenzuela, Sudhir K. Yadav, Sridhar Boppana, Suhayl Dhib-Jalbut, Kouichi Ito> ;Journal of Neuroimmunology. 2017 Mar 15
Obituary-Omar Khan, MD, Professor and Chair of Neurology and Neurologist-in-Chief of the Detroit Medical Center.
Lisak RP, Dhib-Jalbut S> ;Mult. Scler.. 2016-10-01
Obituary-Omar Khan, MD, Professor and Chair of Neurology and Neurologist-in-Chief of the Detroit Medical Center.
Robert P Lisak, Suhayl Dhib-Jalbut> ;Multiple Sclerosis. 2016 Oct 1
224 citations
Brain health: time matters in multiple sclerosis
Gavin Giovannoni, Helmut Butzkueven, Suhayl Dhib-Jalbut, Jeremy Hobart, Gisela Kobelt, George Pepper, Maria Pia Sormani, Christoph Thalheim, Anthony Traboulsee, Timoth...> ;Multiple Sclerosis and Related Disorders. 2016 Sep 1
3 citations
Friend or foe? Targeting microglia in Alzheimer’s disease
Suhayl Dhib-Jalbut> ;Cytokine. 2016 Oct 1
13 citations
Further understanding of the immunopathology of multiple sclerosis: impact on future treatments
Vikram Bhise, Suhayl Dhib-Jalbut> ;Expert Review of Clinical Immunology. 2016 Jun 23
128 citations
Estriol combined with glatiramer acetate for women with relapsing-remitting multiple sclerosis: a randomised, placebo-controlled, phase 2 trial.
Rhonda R. Voskuhl, He-Jing Wang, T. C. Jackson Wu, Nancy L. Sicotte, Kunio Nakamura, Florian Kurth, Noriko Itoh, Jenny Bardens, Jacqueline Bernard, John R. Corboy, Ann...> ;The Lancet. Neurology. 2016 Jan 1
16 citations
Microglia and necroptosis: The culprits of neuronal cell death in multiple sclerosis.
Suhayl Dhib-Jalbut, Dhan V. Kalvakolanu> ;Cytokine. 2015 Dec 1
91 citations
Advances in the immunopathogenesis of multiple sclerosis.
Sudhir K. Yadav, John E. Mindur, Kouichi Ito, Suhayl Dhib-Jalbut> ;Current Opinion in Neurology. 2015 Jun 1
3 citations
The choroid plexus and the paradox of interferons in the aging brain.
Suhayl Dhib-Jalbut> ;Cytokine. 2015 Feb 1
47 citations
MMP-9 expression is increased in B lymphocytes during multiple sclerosis exacerbation and is regulated by microRNA-320a
Latt Latt Aung, M. Maral Mouradian, Suhayl Dhib-Jalbut, Konstantin E. Balashov> ;Journal of Neuroimmunology. 2015 Jan 15
1 citations
Introduction to a special issue on cytokines in neuroinflammation and immunity.
Suhayl Dhib-Jalbut, Dhan V. Kalvakolanu> ;Journal of Interferon & Cytokine Research. 2014 Aug 1
6 citations
Biomarkers of interferon Beta therapy in multiple sclerosis.
Jerome J. Graber, Suhayl Dhib-Jalbut> ;Journal of Interferon & Cytokine Research. 2014 Aug 1
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Journal Articles

Current use of biomarkers to guide MS therapies
Dhib-Jalbut SS, IJMSC, 10/1/2013
From emerging agents to biomarkers: Integrating scientific advances into MS management
Dhib-Jalbut SS, Markowitz CE, Miller A, IJMSC, 1/1/2013
Immune response during Interferon-beta-1b treatment in patients with multiple sclerosis who experienced relapses and those who were relapse free in the START study
Dhib-Jalbut SS, Sumandeep S, Valenzuela RM, Ito K, Patel P, Rametta M, J Neuroimmunol, 1/1/2013
Effect if interferon beta-1a on B71 and B72 B-cell expression and its impact on T-cell proliferation
Huang H, Ito K, Dangond F, Dhib-Jalbut SS, J Neuroimmunol, 1/1/2013
Hematopietic progenitors expree myelin basic protein and ensheath axons in Shiverer brain
Goolsby J, Makar T, Dhib-Jalbut SS, Bever C, Pessac B, Trisler D, J Neuroimmunol, 1/1/2013
Are Periventricular lesions specific for MS?
Casini G, Yurashevich M, Dash S, Dhib-Jalbut SS, Gerhardstein B, Balashov K, J Neurology & Neurophysiology, 1/1/2013
HLA Dr and DQ alleles and Haplotypes associated with clinical response to Glatiramer Acetate in multiple Sclerosis
Dhib-Jalbut SS, Valenzuela RM, Ito K, Kaufman M, Picone MA, Buyske S, Multiple Sclerosis, 1/1/2013
Comparison of IFN-B inducible gene expression in primary progressive and relapsing-remitting multiple sclerosis
Boppana S, Mindur JE, Balashov KE, Dhib-Jalbut SS, Ito K, J Neuroimmunol, 1/1/2013
Use of Magnetic resonance imaging as well as clinical disease activity in the clinical classification of multiple sclerosis and assessment of its course
Cook SD, Dhib-Jalbut SS. et. Al, IJMSC, 1/1/2012
The combined effect of nursing support and Adverse event mitigation on adherence to Interferon Beta-1b therapy in early multiple sclerosis
Dhib-Jalbut SS, Markowitz C, Patel P, Boateng F, Rametta M, for the START Study Group, IJMSC, 1/1/2012
Immunologic aspects of multiple sclerosis
Boppana S, Huang H, Ito K, Dhib-Jalbut SS, Mount Sinai Journal of Medicine, 1/1/2011
Biomarkers in Multiple Sclerosis
Graber J and Dhib-Jalbut SS, J Neurological Sciences, 1/1/2011
Overlapping and distinct mechanisms of action of multiple sclerosis therapies
Graber J, McGraw CA, Kimbrough D, Dhib-Jalbut SS, Clinical Neurology and Neurosurgery, 9/1/2010
Multiple Sclerosis Disease-Modifying Therapies: Mechanisms of Action and Practical Implications
Dhib-Jalbut SS, Neurology, 1/1/2010
Protective immunity in the nervous system
Graber J, Dhib-Jalbut SS, Pharmacology & Therapeutics, 1/1/2009
Recognizing and treating suboptimally controlled multiple sclerosis:steps toward regaining command
Freedman M, Cohen B, Dhib-Jalbut SS, Jeffrey D, Reder A, Sandberg-Wolheim M, Weinstock-Guttman B, Current Medical Research & Opinion, 1/1/2009
Brain-derived neurotrophic factor gene delivery in an animal model of multiple sclerosis using bone marrow cells as a vehicle
Makar T, Bever C, Singh I, Royal W, Sahu S, Sura T, Sultana S, Sura K, Patel N, Dhib-Jalbut SS, Trisler D, J Neuroimmunol, 1/1/2009
Stem cell-based delivery of IFN-B reduces relapses in Experimental Autoimmune Encephalomyelitis
Makar TK, Trisler D, Bever CT, Goolsby KT, Sura KT, Balasubramanian S, Sultana S, Patel N, Ford D, Singh IS, Gupta A, Valenzuela RM, Dhib-Jalbut SS, J Neuroimmunology, 1/1/2008
Protective Autoimmunity
Dhib-Jalbut SS, Johns Hopkins Advanced Studies in Medicine, 1/1/2007
Cytokine changes during interferon-beta therapy in multiple sclerosis: Correlation with interferon dose and MRI response
Graber J, Ford D, Zhan M, Francis G, Panitch H, Dhib-Jalbut SS, J Neuroimmunol, 1/1/2007
Ex-Vivo cellular IL-4/IFN-gamma correlates with clinical response to Glatiramer acetate in multiple sclerosis
Valenzuela R, Costello K, Johnson KP, Dhib-Jalbut SS, Multiple Sclerosis, 1/1/2007
Pathogenesis of Myelin/Olgodendrocyte damage in Multiple Sclerosis
Dhib-Jalbut SS, Neurology, 1/1/2007
Immunomodulation and the basis for multiple sclerosis therapy
Dhib-Jalbut SS, International Journal of MS care, 1/1/2006
Neuroprotection iin multiple sclerosis
Dhib-Jalbut SS, International Journal of MS care, 1/1/2006
Cellular immunological biomarkers of therapeutic response in multiple sclerosis
Dhib-Jalbut SS, International Journal of MS care, 1/1/2006
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Lectures

Minimizing Risks and Maximizing Efficacy for Management of Multiple Sclerosis
CMEducation Resources, LLC, San Jose, California - 4/20/2013
Minimizing Risks and Maximizing Efficacy for Management of Multiple Sclerosis
CMEducation Resources, LLC, Dallas, Texas - 4/13/2013
Minimizing Risks and Maximizing Efficacy for Management of Multiple Sclerosis
CMEducation Resources, LLC, Atlanta, Georgia - 4/6/2013

Press Mentions

Rutgers to Open Alzheimer’s and Dementia Clinical Research and Treatment CenterFebruary 1st, 2023
What to Expect at CMSC 2016May 31st, 2016

Grant Support

Bdnf-Engineered Stem Cell Mediated Neuroprotection In EAENational Institute Of Neurological Disorders And Stroke2009–2010
Interferon-B And Copolymer-I In Multiple Sclerosis.National Institute Of Neurological Disorders And Stroke2003
Interferon-B And Copolymer-I In Multiple Sclerosis.National Institute Of Neurological Disorders And Stroke1999–2002
Regulation &Function Of Class-Ii HLA Molecules In Measles Infected Human GliaNational Institute Of Neurological Disorders And Stroke1992–1996