Sunil Singhal MD

Thoracic Surgery•Philadelphia, PA

Cardiovascular Surgery

Professor, Surgery, University of Pennsylvania Perelman School of Medicine

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3400 Spruce StFl 6Philadelphia, PA 19104
Phone+1 215-662-4767
Fax+1 215-349-5798

Education & Training

University of Pennsylvania Health SystemFellowship, Thoracic Surgery - Independent, 2005 - 2007
Johns Hopkins UniversityResidency, Surgery, 1998 - 2005
Perelman School of Medicine at the University of PennsylvaniaClass of 1998

Certifications & Licensure

NJ State Medical License 2010 - 2027
PA State Medical License 2001 - 2026
GA State Medical License 2007 - 2009
American Board of Surgery Surgery
American Board of Thoracic Surgery Thoracic and Cardiac Surgery

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012
Fellow (FACS) American College of Surgeons

Clinical Trials

Intraoperative Imaging of Thoracic Malignancies With Indocyanine Green Start of enrollment: 2011 May 01
Completed
Phase 1
Pilot and Feasibility Study of the Imaging Potential of EC17: Intraoperative Folate-fluorescein Conjugate (EC17) Lung Cancer (CA) Start of enrollment: 2012 Apr 01
Completed
Phase 1
Intraoperative Imagery of Renal Nodules With Folate-fluorescein Conjugate(EC17) Start of enrollment: 2013 May 01
Completed
Early Phase 1
Intraoperative Imaging of Breast Cancer With Indocyanine Green Start of enrollment: 2011 Jul 01
Completed
Early Phase 1
Intraoperative Imagery of Breast Cancer With Folate-FITC (EC17) Start of enrollment: 2014 May 01
Completed
Phase 1
EC17 for Intraoperative Imaging for Parathyroidectomy Start of enrollment: 2013 Nov 01
Completed
Phase 1
EC17 for Intraoperative Imaging in Occult Ovarian Cancer Start of enrollment: 2013 Nov 01
Completed
Phase 1
Intraoperative Imaging of Pituitary Adenomas by OTL Start of enrollment: 2015 Oct 01
Terminated
Phase 1
Intraoperative Imaging With ICG Registry Start of enrollment: 2016 Jul 01
Completed
Optional Sub-study to Intraoperative Imaging With ICG Registry Start of enrollment: 2015 Dec 01
Completed
Intraoperative Imaging of Pulmonary Adenocarcinoma Start of enrollment: 2016 Jan 01
Withdrawn
Phase 1
A Pilot & Feasibility Study of Intraoperative Imaging With OTL38 In Patients With Lung and Pleural Nodules Start of enrollment: 2015 Jun 01
A Phase 1, Single Dose, Open-Label Study to Investigate the Safety and Efficacy of OTL38 Injection (OTL38) for Intra-operative Imaging of Folate Receptor-alpha Positive Pituitary Adenoma Start of enrollment: 2015 Sep 01
Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer Start of enrollment: 2019 Jun 17
Recruiting
Phase 3
OTL38 Injection (OTL38) for Intra-Operative Imaging of Folate Receptor Positive Ovarian Cancer Start of enrollment: 2022 May 28
Withdrawn
Phase 1
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Publications & Presentations

PubMed

Characterizing the Clinical and Molecular Profile of SETD2-Mutated Lung Adenocarcinoma.
Omar Bushara, David Devaro, Shawn S Ahn, Jordan Dourlain, Mohammad S Farooq
Cancers. 2025-11-01
Pulmonary Sclerosing Pneumocytoma Masquerading as a Carcinoid Tumor.
Rucha Alur, Omar Bushara, Anna Garcia Whitlock, Alessandro Brunetti, Roseann Wu
Clinical Lung Cancer. 2025-11-01
Epithelial Cell Adhesion Molecule Is an Accurate Target for Fluorescence Guided Imaging of Lymph Nodes.
Kelly Anne McGovern, Katherine O Welch, Ryan Krouse, Michael Brown, Lydia Chen
Molecular Imaging and Biology. 2025-10-14

Journal Articles

Implications of Hospital Volume on Costs Following Esophagectomy in the United States
Gregory T Kennedy, Sunil Singhal, John C Kucharczuk, Jarrod D Predina, Andrew D Newton, Journal of gastrointestinal surgery

Press Mentions

Vergent Bioscience Presents Phase 2B VISUALIZE Results Demonstrating Abenacianine for Injection (VGT-309) with Intraoperative Molecular Imaging Improved Tumor Visualization During Lung SurgeryMay 22nd, 2025
Artificial Intelligence Guided Intraoperative Molecular Imaging Biopsy of Indeterminate Pulmonary Nodules During Robotic SurgeryMay 8th, 2023
FDA Approves Drug Which Makes Lung Cancer GlowDecember 29th, 2022
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Grant Support

Clinical Translation of a Choline-targeted NIR dye to guide lung cancer resectionUNIVERSITY OF PENNSYLVANIA2025–2030
Intraoperative Near Infrared Molecular Imaging of Lung CancerUNIVERSITY OF PENNSYLVANIA2022–2027
Intraoperative Near Infrared Molecular Imaging of Lung CancerUNIVERSITY OF PENNSYLVANIA2022–2027
Translating phospholipase activatable fluorophores for the sensitive detection of non-small cell lung cancerUNIVERSITY OF PENNSYLVANIA2022–2027