SusanLMcelroyMD

Psychosomatic Medicine

Professor of Psychiatry and Chief Research Officer and Director of Psychopharmacology Research at the Lindner Center of HOPE

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Office
234 Goodman St
Cincinnati, OH 45219
Phone+1 513-584-1000

Fax+1 513-584-3755
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Education & Training

Massachusetts General Hospital/McLean HospitalResidency, Psychiatry, 1984 - 1988
New York Presbyterian Hospital (Columbia Campus)Internship, Internal Medicine, 1983 - 1984
Weill Cornell MedicineClass of 1983

Certifications & Licensure

OH State Medical License 1991 - 2026
American Board of Psychiatry and Neurology Psychiatry

Clinical Trials

A Study of Risperidone Monotherapy in Bipolar Anxiety Start of enrollment: 2003 Sep 01
Completed
Phase 4
Zonegran in the Treatment of Binge Eating Disorder Associated With Obesity Start of enrollment: 2005 Aug 01
Completed
Phase 3
Lamotrigine in the Treatment of Binge Eating Disorder Associated With Obesity Start of enrollment: 2006 Mar 01
Completed
Phase 3
Study of Risperidone Monotherapy in Ambulatory Bipolar Disorder With Concurrent Moderately Severe Anxiety and Lifetime Panic or Generalized Anxiety Disorder Start of enrollment: 2004 Feb 01
Completed
Phase 3
Study of Quetiapine Monotherapy in Ambulatory Bipolar Spectrum Disorder With Moderate-to-Severe Hypomanic Symptoms or Mild Manic Symptoms Start of enrollment: 2004 Feb 01
Completed
Phase 3
Study of Divalproex Extended Release Monotherapy in Ambulatory Bipolar Spectrum Disorder With Moderate-to-Severe Hypomania or Mild Mania Start of enrollment: 2003 Aug 01
Completed
Phase 3
Atomoxetine in the Treatment of Binge Eating Disorder Start of enrollment: 2006 May 01
Completed
Phase 4
A Preliminary Study of the Effectiveness and Tolerability of Aripiprazole in Bipolar Depression Start of enrollment: 2006 Aug 01
Completed
Phase 4
Safety and Efficacy Trial of Olanzapine in Outpatients With Pathological Gambling Start of enrollment: 2007 Feb 01
Completed
Phase 3
Acamprosate in the Treatment of Binge-Eating Disorder Start of enrollment: 2007 Apr 01
Completed
Phase 2, Phase 3
Sodium Oxybate in the Treatment of Binge Eating Disorder Start of enrollment: 2007 Aug 01
Completed
Phase 2, Phase 3
Add-On Ramelteon in Bipolar I Disorder With Clinically Significant Sleep Disturbance Start of enrollment: 2007 Dec 01
Terminated
Phase 3
Efficacy and Safety Study of Low-Dose Ondansetron For Adjunctive Therapy In Adult Patients With Obsessive-Compulsive Disorder Start of enrollment: 2011 Jan 01
Terminated
Phase 2
SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder Start of enrollment: 2012 Nov 26
Completed
Phase 3
SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder Start of enrollment: 2012 Nov 26
Completed
Phase 3
Study of Intravenous NRX-1074 in Patients With Major Depressive Disorder Start of enrollment: 2014 Mar 01
Completed
Phase 2
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Publications & Presentations

PubMed

Question: What Is the Current State of Evidence Regarding Any Mood-Improving Properties of GLP-1 Receptor Agonists, and Are Psychiatrists Prescribing Them?
Susan L McElroy> ;Journal of Clinical Psychopharmacology. 2024 Apr 18
Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study.
Anna H Ou, Sara B Rosenthal, Mazda Adli, Kazufumi Akiyama, Nirmala Akula, Martin Alda, Azmeraw T Amare, Raffaella Ardau, Bárbara Arias, Jean-Michel Aubry, Lena Backlun...> ;Translational Psychiatry. 2024 Feb 23
Standard Binge Eating Treatments Are Not Effective for My Patient: What Should I Try Next?
McElroy, S.> ;Journal of Clinical Psychopharmacology. 2023 Dec 15
16 citations
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.
Anna R Docherty, Niamh Mullins, Allison E Ashley-Koch, Xuejun Qin, Jonathan R I Coleman, Andrey Shabalin, JooEun Kang, Balasz Murnyak, Frank Wendt, Mark Adams, Adrian ...> ;The American Journal of Psychiatry. 2023 Oct 1
2 citations
Efficacy, safety, and tolerability of nivasorexant in adults with binge-eating disorder: A randomized, Phase II proof of concept trial.
Susan L McElroy, Preciosa M Coloma, Benjamin Berger, Anna I Guerdjikova, J Mark Joyce, Michael R Liebowitz, Scott Pain, Cristina Rabasa> ;The International Journal of Eating Disorders. 2023 Nov 1
5 citations
Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder.
Azmeraw T Amare, Anbupalam Thalamuthu, Klaus Oliver Schubert, Janice M Fullerton, Muktar Ahmed, Simon Hartmann, Sergi Papiol, Urs Heilbronner, Franziska Degenhardt, Fa...> ;Molecular Psychiatry. 2023 Dec 1
KIOS: A smartphone app for self-monitoring for patients with bipolar disorder.
Mehak Pahwa, Susan L McElroy, Richard Priesmeyer, Gregg Siegel, Phyllis Siegel, Sharon Nuss, Charles L Bowden, Rif S El-Mallakh> ;Bipolar Disorders. 2024 Feb 1
1 citations
Clinical characterization of patients with bipolar disorder and a history of asthma: An exploratory study.
Francisco Romo-Nava, Thomas Blom, Alfredo B Cuellar-Barboza, Francisco J Barrera, Alessandro Miola, Nicole N Mori, Miguel L Prieto, Marin Veldic, Balwinder Singh, Manu...> ;Journal of Psychiatric Research. 2023 Aug 1
17 citations
World Federation of Societies of Biological Psychiatry (WFSBP) guidelines update 2023 on the pharmacological treatment of eating disorders.
Hubertus Himmerich, Yael Doreen Lewis, Chiara Conti, Hiba Mutwalli, Andreas Karwautz, Jan Magnus Sjögren, María Mercedes Uribe Isaza, Marta Tyszkiewicz-Nwafor, Martin ...> ;The World Journal of Biological Psychiatry. 2023 Apr 24
4 citations
Insulin resistance in bipolar disorder: A systematic review of illness course and clinical correlates.
Alessandro Miola, Neri A Alvarez-Villalobos, Fernando Gerardo Ruiz-Hernandez, Eleanna De Filippis, Marin Veldic, Miguel L Prieto, Balwinder Singh, Jorge A Sanchez Ruiz...> ;Journal of Affective Disorders. 2023 Aug 1
2 citations
Weight changes in adults with major depressive disorder: A systematic review and meta-analysis of prospective studies.
Andrés Marcelo Treviño-Alvarez, Jorge Andrés Sánchez-Ruiz, Francisco J Barrera, Mario Rodríguez-Bautista, Francisco Romo-Nava, Susan L McElroy, Alfredo B Cuéllar-Barboza> ;Journal of Affective Disorders. 2023 Jul 1
2 citations
Pharmacotherapy exposure as a marker of disease complexity in bipolar disorder: Associations with clinical & genetic risk factors.
Jorge A Sanchez Ruiz, Brandon J Coombes, Richard S Pendegraft, Aysegul Ozerdem, Susan L McElroy, Alfredo B Cuellar-Barboza, Miguel L Prieto, Mark A Frye, Stacey J Winh...> ;Psychiatry Research. 2023 May 1
5 citations
Long-Term Lithium Therapy and Thyroid Disorders in Bipolar Disorder: A Historical Cohort Study.
Boney Joseph, Nicolas A Nunez, Vanessa Pazdernik, Rakesh Kumar, Mehak Pahwa, Aysegul Ozerdem, Alfredo B Cuellar-Barboza, Francisco Romo-Nava, Susan L McElroy, Brandon ...> ;Brain Sciences. 2023 Jan 12
6 citations
Real-World Clinical Practice Among Patients With Bipolar Disorder and Chronic Kidney Disease on Long-term Lithium Therapy.
Rakesh Kumar, Boney Joseph, Vanessa M Pazdernik, Jennifer Geske, Nicolas A Nuñez, Mehak Pahwa, Kianoush B Kashani, Marin Veldic, Hannah K Betcher, Katherine M Moore, P...> ;Journal of Clinical Psychopharmacology. 2022 Dec 30
5 citations
Antidepressants that increase mitochondrial energetics may elevate risk of treatment-emergent mania.
Manuel Gardea-Resendez, Brandon J Coombes, Marin Veldic, Susannah J Tye, Francisco Romo-Nava, Aysegul Ozerdem, Miguel L Prieto, Alfredo Cuellar-Barboza, Nicolas A Nune...> ;Molecular Psychiatry. 2023 Mar 1
15 citations
Predictors of functional impairment in bipolar disorder: Results from 13 cohorts from seven countries by the global bipolar cohort collaborative.
Katherine E Burdick, Caitlin E Millett, Anastasia K Yocum, Cara M Altimus, Ole A Andreassen, Valerie Aubin, Raoul Belzeaux, Michael Berk, Joanna M Biernacka, Hilary P ...> ;Bipolar Disorders. 2022 Nov 1
1 citations
An exploratory machine learning approach to identify placebo responders in pharmacological binge eating disorder trials.
Rahul K Goyal, Shamir N Kalaria, Susan L McElroy, Mathangi Gopalakrishnan> ;Clinical and Translational Science. 2022 Dec 1
5 citations
The genetics of bipolar disorder with obesity and type 2 diabetes.
Alessandro Miola, Eleanna De Filippis, Marin Veldic, Ada Man-Choi Ho, Stacey J Winham, Mariana Mendoza, Francisco Romo-Nava, Nicolas A Nunez, Manuel Gardea Resendez, M...> ;Journal of Affective Disorders. 2022 Sep 15
4 citations
Quantification of diet quality utilizing the rapid eating assessment for participants-shortened version in bipolar disorder: Implications for prospective depression an...
Manuel Gardea-Resendez, Stacey J Winham, Francisco Romo-Nava, Alfredo Cuellar-Barboza, Matthew M Clark, Ana Cristina Andreazza, Alejandra Cabello-Arreola, Marin Veldic...> ;Journal of Affective Disorders. 2022 Aug 1
Correction: Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients.
Klaus Oliver Schubert, Anbupalam Thalamuthu, Azmeraw T Amare, Joseph Frank, Fabian Streit, Mazda Adl, Nirmala Akula, Kazufumi Akiyama, Raffaella Ardau, Bárbara Arias, ...> ;Translational Psychiatry. 2022 Jul 11
1 citations
Are personality disorders in bipolar patients more frequent in the US than Europe?
Robert M Post, Gabriele S Leverich, Susan L McElroy, Ralph Kupka, Trisha Suppes, Lori L Altshuler, Willem A Nolen, Mark A Frye, Paul E Keck, Heinz Grunze, Michael Rowe> ;European Neuropsychopharmacology. 2022 May 1
6 citations
Cardiometabolic risk markers during mood-stabilizing treatment: Correlation with drug-specific effects, depressive symptoms and treatment response.
Maya Kuperberg, Ole Köhler-Forsberg, Alec P Shannon, Nevita George, Sophie Greenebaum, Charles L Bowden, Joseph R Calabrese, Michael Thase, Richard C Shelton, Melvin M...> ;Journal of Affective Disorders. 2022 Mar 1
12 citations
Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach.
Micah Cearns, Azmeraw T Amare, Klaus Oliver Schubert, Anbupalam Thalamuthu, Joseph Frank, Fabian Streit, Mazda Adli, Nirmala Akula, Kazufumi Akiyama, Raffaella Ardau, ...> ;The British Journal of Psychiatry. 2022 Feb 28
Clinical Phenotype of Tardive Dyskinesia in Bipolar Disorder.
Manuel Gardea-Resendez, Monica J Taylor-Desir, Francisco Romo-Nava, David Bond, Eric J Vallender, Alfredo B Cuellar-Barboza, Miguel L Prieto, Nicolas Nunez, Marin Veld...> ;Journal of Clinical Psychopharmacology. 2022 Feb 25
5 citations
Lithium plus antipsychotics or anticonvulsants for bipolar disorder: Comparing clinical response and metabolic changes.
Ole Köhler-Forsberg, Louisa G Sylvia, Michael Thase, Joseph R Calabrese, Mauricio Tohen, Charles L Bowden, Melvin McInnis, Dan V Iosifescu, James H Kocsis, Edward S Fr...> ;The Australian and New Zealand Journal of Psychiatry. 2023 Jan 1
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Press Mentions

How to Treat Binge Eating by Patients with Bipolar DisorderJuly 4th, 2019
High Rate of Eating Disorders in Bipolar PatientsJune 17th, 2019
Sunovion Announces Positive Top-Line Results from Pivotal Study Evaluating Dasotraline in Adults with Binge Eating DisorderAugust 31st, 2018
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Hospital Affiliations

University of Cincinnati Medical CenterCincinnati, Ohio
Lindner Center of HOPEMason, Ohio