Tae-HwaChunMDPhD

PubMed

• Safety and effectiveness of metabolic surgery in older Japanese patients.
  Minoru Takemoto, Aiko Hayashi, Yosuke Inaba, Tomohiro Tanaka, Tae-Hwa Chun, Hideki Hayashi, Kazunori Kasama, Atsuhito Saiki, Akira Sasaki, Shinichi Okazumi, Hisahiro M...> ;Annals of Gastroenterological Surgery. 2023 Sep 1
• 1 citations
  Monolithically 3D-Printed Microfluidics with Embedded µTesla Pump.
  Kai Duan, Mohamad Orabi, Alexus Warchock, Zaynab Al-Akraa, Zeinab Ajami, Tae-Hwa Chun, Joe F Lo> ;Micromachines. 2023 Jan 17
• 62 citations
  HIF2A-LOX Pathway Promotes Fibrotic Tissue Remodeling in Thyroid-Associated Orbitopathy.
  Fumihito Hikage, Stephen J. Atkins, Alon Kahana, Terry J. Smith, Tae Hwa Chun> ;Endocrinology. 2019 Jan 1
• 41 citations
  Fibro-Adipogenic Remodeling of the Diaphragm in Obesity-Associated Respiratory Dysfunction
  Eric D. Buras, Kimber Converso-Baran, Carol S. Davis, Takeshi Akama, Fumihito Hikage, Daniel E. Michele, Susan V. Brooks, Tae Hwa Chun> ;Diabetes. 2019 Jan 1
• 18 citations
  Transcription factor 21 (TCF21) promotes proinflammatory interleukin 6 expression and extracellular matrix remodeling in visceral adipose stem cells
  Takeshi Akama, Tae Hwa Chun> ;The Journal of Biological Chemistry. 2018 Apr 27
• 11 citations
  Membrane-tethered metalloproteinase expressed by vascular smooth muscle cells limits the progression of proliferative atherosclerotic lesions
  Richard H. Barnes, Takeshi Akama, Miina K. Öhman, Moon Sook Woo, Julian C. Bahr, Stephen J. Weiss, Daniel T. Eitzman, Tae Hwa Chun> ;Journal of the American Heart Association. 2017 Jul 22
• 8 citations
  Designing 3-D Adipospheres for Quantitative Metabolic Study.
  Takeshi Akama, Brendan M. Leung, Joseph M. Labuz, Shuichi Takayama, Tae Hwa Chun> ;Methods in Molecular Biology. 2017 Jan 1
• 138 citations
  Adipose extracellular matrix remodelling in obesity and insulin resistance.
  De Lin, Tae Hwa Chun, Li Kang> ;Biochemical Pharmacology. 2016 Nov 1
• 2 citations
  Immunomagnetic Separation of Fat Depot-specific Sca1high Adipose-derived Stem Cells (ASCs)
  Richard H. Barnes, Tae Hwa Chun> ;Journal of Visualized Experiments. 2016 Aug 11
• 56 citations
  Thrombospondin 1 as a novel biological marker of obesity and metabolic syndrome
  Yoshiyuki Matsuo, Masashi Tanaka, Hajime Yamakage, Yousuke Sasaki, Kazuya Muranaka, Hiroaki Hata, Iwao Ikai, Akira Shimatsu, Mayumi Inoue, Tae Hwa Chun, Noriko Satoh-A...> ;Metabolism. 2015 Nov 1
• 8 citations
  The Exocyst Complex Regulates Free Fatty Acid Uptake by Adipocytes
  Mayumi Inoue, Takeshi Akama, Yibin Jiang, Tae Hwa Chun> ;Plos One. 2015 Mar 13
• 23 citations
  Fat depot-specific gene signature and ECM remodeling of Sca1high adipose-derived stem cells
  Masakuni Tokunaga, Mayumi Inoue, Yibin Jiang, Richard H. Barnes, David A. Buchner, Tae Hwa Chun> ;Matrix Biology. 2014 Jun 1
• 12 citations
  3-D adipocyte differentiation and peri-adipocyte collagen turnover.
  Tae Hwa Chun, Mayumi Inoue> ;Methods in Enzymology. 2014 Jan 1
• 58 citations
  Thrombospondin 1 mediates high-fat diet-induced muscle fibrosis and insulin resistance in male mice.
  Mayumi Inoue, Yibin Jiang, Richard H. Barnes, Masakuni Tokunaga, Gabriel Martinez-Santibanez, Lynn M. Geletka, Carey N. Lumeng, David A. Buchner, Tae Hwa Chun> ;Endocrinology. 2013 Sep 30
• 98 citations
  On being the right size: scaling effects in designing a human-on-a-chip
  Christopher Moraes, Joseph M. Labuz, Brendan M. Leung, Mayumi Inoue, Tae Hwa Chun, Shuichi Takayama> ;Integrative Biology. 2013 Aug 19
• 71 citations
  Peri-adipocyte ECM remodeling in obesity and adipose tissue fibrosis
  Tae Hwa Chun> ;Adipocyte. 2012 Apr 1
• 18 citations
  Adipogenic histone mark regulation by matrix metalloproteinase 14 in collagen-rich microenvironments.
  Kaori Sato-Kusubata, Yibin Jiang, Yoko Ueno, Tae Hwa Chun> ;Molecular Endocrinology. 2011 Mar 24
• 73 citations
  Genetic link between obesity and MMP14-dependent adipogenic collagen turnover.
  Tae Hwa Chun, Mayumi Inoue, Hiroko Morisaki, Itaru Yamanaka, Yoshihiro Miyamoto, Tomonori Okamura, Kaori Sato-Kusubata, Stephen J. Weiss> ;Diabetes. 2010 Oct 1
• 295 citations
  A pericellular collagenase directs the 3-dimensional development of white adipose tissue
  Stephen J. Weiss, Tae Hwa Chun> ;Cell. 2007 Apr 2
• 105 citations
  MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells
  Sergey Filippov, Gerald C. Koenig, Tae Hwa Chun, Kevin B. Hotary, Ichiro Ota, Thomas H. Bugge, Joseph Roberts, William P. Fay, Henning Birkedal-Hansen, Kenn Holmbeck, ...> ;The Journal of Experimental Medicine. 2005 Sep 5
• 12 citations
  Angiotensin II suppresses growth arrest specific homeobox (Gax) expression via redox-sensitive mitogen-activated protein kinase (MAPK).
  Takatoshi Saito, Hiroshi Itoh, Jun K. Yamashita, Kentaro Doi, Tae Hwa Chun, Tokuji Tanaka, Mayumi Inoue, Ken Masatsugu, Yasutomo Fukunaga, Naoki Sawada, Satsuki Sakagu...> ;Regulatory Peptides. 2005 Apr 15
• 96 citations
  An MT1-MMP-PDGF receptor-β axis regulates mural cell investment of the microvasculature
  Kaisa Lehti, Edward D. Allen, Henning Birkedal-Hansen, Kenn Holmbeck, Yasuhiro Miyake, Tae Hwa Chun, Stephen J. Weiss> ;Genes & Development. 2005 Apr 15
• 38 citations
  Therapeutic potential of thiazolidinediones in activation of peroxisome proliferator-activated receptor γ for monocyte recruitment and endothelial regeneration
  Tokuji Tanaka, Yasutomo Fukunaga, Hiroshi Itoh, Kentaro Doi, Jun K. Yamashita, Tae Hwa Chun, Mayumi Inoue, Ken Masatsugu, Takatoshi Saito, Naoki Sawada, Satsuki Sakagu...> ;European Journal of Pharmacology. 2005 Jan 31
• 257 citations
  MT1-MMP–dependent neovessel formation within the confines of the three-dimensional extracellular matrix
  Tae Hwa Chun, Farideh Sabeh, Ichiro Ota, Hedwig S. Murphy, Kevin T. McDonagh, Kenn Holmbeck, Henning Birkedal-Hansen, Edward D. Allen, Stephen J. Weiss> ;The Journal of Cell Biology. 2004 Nov 22
• 53 citations
  Modification of GATA-2 Transcriptional Activity in Endothelial Cells by the SUMO E3 Ligase PIASy
  Tae Hwa Chun, Hiroshi Itoh, Lalitha Subramanian, Jorge A. Iñiguez-Lluhí, Kazuwa Nakao> ;Circulation Research. 2003 Jun 13
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Books/Book Chapters

• Natriuretic Peptides in Health and Disease 
  Chapter: Cellular and Molecular Aspects of C-Type Natriuretic Peptide (CNP) 
  Page 107 - 122Itoh H, Suga S, Ogawa Y, Komatsu Y, Tamura N, Igaki T, Yamashita J, Doi K, Chun T-H, Inoue M, Masatsugu K, Ikeda T, Shirakami G, Matsuda K, Katsuura G, Ueda M, Ban T, ...Editors: Samson W, Levin E.Humana Press1997

Abstracts/Posters

• Adipose ECM-derived Protein Mediates HFD-induced Muscle Fibrosis and Insulin Resistance
  Mayumi Inoue, Yibin Jiang, Carey Lumeng, David Buchner, Tae-Hwa Chun, Keystone Symposia. Challenges and Opportunities in Diabetes Research and Treatment, Vancouver, British Columbia, Canada, 1/13/2014
• Fat Depot-specific Gene Signature and ECM Remodeling
  Masakuni Tokunaga, Mayumi Inoue, Yibin Jiang, Richard Barnes II, David Buchner, Tae-Hwa Chun, Keystone Symposia. Challenges and Opportunities in Diabetes Research and Treatment, Vancouver, British Columbia, Canada, 1/13/2014
• Fat Depot-specific Gene Signature and ECM Remodeling of Adipose Tissue Stem Cells
  Masakuni Tokunaga, Mayumi Inoue, Yibin Jiang, David A. Buchner, Tae-Hwa Chun, Cell Symposia, Using Stem Cells to Model and Treat Human Diseases, Los Angeles, USA, 11/21/2013
• Mmp14-dependent Paradoxical Link between Obesity and Atherosclerosis
  Tae-Hwa Chun, Miina Ohman, Daniel Eitzman, Jiang Yibin, Mayumi Inoue, American Heart Association, Scientific Sessions 2013, Dallas, TX, 11/19/2013
• Stretchable Rectangular Microwells for Single Cell Capture
  Joseph M. Labuz, Msakuni Tokunaga, Tae-Hwa Chun, Shuichi Takayama, 7th International Conference on Microtechnologies in Medicine and Biology (MMB) 2013, Marina del Rey, California, USA, 1/1/2013
• Fat Depot-specific ECM Remodeling and Adipogenesis
  Masakuni Tokunaga, Mayumi Inoue, Yibin Jiang, Tae-Hwa Chun, Plenary Oral Presentation. 20th Annual Research Symposium, Internal Medicine, University of Michigan, Ann Arbor, MI, 3/17/2012
• Thrombospondin 1 as an ECM-derived Modifier of Adipocyte Function in Obesity
  Mayumi Inoue, Masakuni Tokunaga, Yibin Jiang, Tae-Hwa Chun, Keystone Symposia. Emerging Insights into Molecular Mechanisms, Santa Fe, NM, 1/29/2012
• Epigenetic Regulation of Peroxisome Prolieferator-activated Receptor Gamma by MMP14-type I Collagen Axis
  Tae-Hwa Chun, Kaori Sato-Kusubata, Yibin Jiang, Mayumi Inoue, NIDDK, Mechanism of Organ Repair & Regeneration, Turf Valley Hotel, Ellicott City, MD, 9/13/2011
• Epigenetic Adipocyte Gene Regulation by Pericellular Collagenase
  Kaori Sato-Kusubata, Yibin Jiang, Tae-Hwa Chun, San Diego, CA, 6/1/2011
• The Role of Thrombospondin1 in Obesity
  Mayumi Inoue, Yibin Jiang, Tae-Hwa Chun, 71st Scientific Sessions of American Diabetes Association, San Diego, CA, 6/1/2011
• Epigenetic Adipocyte Gene Regulation by Pericellular Collagenase
  Kaori Sato-Kusubata, Yibin Jiang, Tae-Hwa Chun, San Diego, CA, 6/1/2011
• Epigenetic Regulation of Peroxisome Proliferator-Activated Receptor Gamma by MMP14-type I Collagen Axis
  Tae-Hwa Chun, 19th Annual Research Symposium, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 5/20/2011
• Diabetes, Insulin Resistance and Metabolic Dysfunction
  Tae-Hwa Chun, Keystone Symposia, Keystone, Colorado, 1/13/2011
• Plenary Abstract Oral Presentation
  Kaori Sato-Kusubata, Yibin Jiang, Tae-Hwa Chun, 18th Annual Research Symposium, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 5/14/2010
• Plenary Abstract Presentation
  Internal Medicine Research Symposium, University of Michigan, Ann Arbor, MI, 5/1/2005
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Lectures

• A New Biological Process That Links Obesity to Diabetes 
  Michael E. DeBakey VA Medical Center, Houston, TX - 5/21/2013
• The Role of MMP14 and Thbs1 in the Regulation of Adipose Tissue Function 
  Copenhagen, Denmark - 8/30/2012
• Peri-Adipocyte ECM Remodeling in Adipose Tissue Fibrosis and Metabolic Syndrome 
  Brigham and Women’s Hospital, Harvard Medical School, Boson, MA - 2/7/2012
• MMP14-Dependent Epigenetic Regulation of Adipogenesis in Collagen-Rich Environments 
  Chicago, IL - 4/15/2011
• Regulation of Adipose Tissue Mass and Function by MMP-Dependent Collagenolysis 
  Joslin Diabetes Center, Harvard Medical School, Boston, MA - 10/19/2010
• Genetic Link of Obesity to Adipogenic Collagen Turnover in Mice and Humans 
  San Diego, CA - 6/20/2010
• Genetic and Epigenetic Regulation of Obesity by ECM Remodeling 
  Kyoto, Japan - 3/28/2010
• Proteolytic Regulation of Stromal Cell Function in Collagen-Rich Microenvironment 
  Yokohama, Japan - 12/11/2009
• Proteolytic Regulation of Chromatin Signature and Cell Differentiation 
  University of Tokyo, Tokyo, Japan - 12/10/2009
• Role of Pericellular Collagenolysis in Obesity Initiation 
  Maebashi, Gunma, Japan - 4/24/2009
• 3-Dimensional Regulation of Adipose Tissue Mass & Function by Matrix Metalloproteinases 
  San Francisco, CA - 6/18/2008
• Collagenolytic Remodeling of Fat Tissue Architecture during Obesity Progression 
  Bethesda, MD - 5/21/2008
• Pericellular Collagenolysis as a Rheostat of Obesity Progression 
  Banff, Canada - 2/22/2008
• 3-Dimensional, Proteolytic Regulation of Cell Morphology and Differentiation 
  University of Tokyo, The Institute of Medical Science, Tokyo, Japan - 11/19/2007
• Proteolytic Regulation of Adipocyte Differentiation in a 3-D Microenvironment 
  Johns Hopkins University, Baltimore, MD - 5/9/2007
• 3-Dimensional Regulation of Angiogenesis & Adipogenesis by a Pericellular Collagenase 
  National Cancer Institute, Frederick, MD - 4/17/2007
• MT1-MMP Regulates Three-Dimensional Adipogenesis in Vitro and in Vivo 
  Bethesda, MD - 11/2/2006
• Regulation of Angiogenesis and Adipogenesis by a Pericellular Collagenase 
  Merck, Rahway, NJ - 9/11/2006
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Other

• Obesity Doesn't Always Guarantee Heart Disease 
  Businessweek.com
  6/21/2010
• Fat-Fighting Chemical Holds Promise 
  MSN.com
  8/27/2009
• Obese May Be Less Likely to Survive Pancreatic Cancer 
  CNN.com
  3/17/2009
• Blood Test Warns of Dangerous ‘Deep Belly’ Fat 
  Washington Post
  7/12/2007
• Immune System Protein Tied to Weight Loss 
  Washington Post
  6/19/2007
• Enzyme Gives Fat Cells Room to Grow 
  The Scientist
  5/4/2006
• Thesis: Role of Shear and Oxidative Stress in the Expression of Vasoactive Peptides, C-type Natriuretic Peptide and Adrenomedullin 
  Chun TH, Kyoto University
  1/1/2001
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