TheodorePaulBraunMDPhD

PubMed

• CITEViz: interactively classify cell populations in CITE-Seq via a flow cytometry-like gating workflow using R-Shiny.
  Garth L Kong, Thai T Nguyen, Wesley K Rosales, Anjali D Panikar, John H W Cheney, Theresa A Lusardi, William M Yashar, Brittany M Curtiss, Sarah A Carratt, Julia E Max...> ;BMC Bioinformatics. 2024 Apr 2
• Predicting transcription factor activity using prior biological information.
  William M Yashar, Joseph Estabrook, Hannah D Holly, Julia Somers, Olga Nikolova, Özgün Babur, Theodore P Braun, Emek Demir> ;Iscience. 2024 Mar 15
• Multicancer Early Detection Tests: An Overview of Early Results From Prospective Clinical Studies and Opportunities for Oncologists.
  Carl Post, Theodore P Braun, Ruth Etzioni, Nima Nabavizadeh> ;JCO Oncology Practice. 2023 Dec 1
• 5 citations
  Systematic benchmarking of single-cell ATAC-sequencing protocols.
  Florian V De Rop, Gert Hulselmans, Chris Flerin, Paula Soler-Vila, Albert Rafels, Valerie Christiaens, Carmen Bravo González-Blas, Domenica Marchese, Ginevra Caratù, S...> ;Nature Biotechnology. 2023 Aug 3
• 1 citations
  sciMET-cap: High-throughput single-cell methylation analysis with a reduced sequencing burden.
  Sonia N Acharya, Ruth V Nichols, Lauren E Rylaarsdam, Brendan L O'Connell, Theodore P Braun, Andrew C Adey> ;Biorxiv. 2023 Jul 14
• 1 citations
  Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia.
  William M Yashar, Brittany M Curtiss, Daniel J Coleman, Jake VanCampen, Garth Kong, Jommel Macaraeg, Joseph Estabrook, Emek Demir, Nicola Long, Daniel Bottomly, Shanno...> ;Molecular Cancer Research. 2023 Jul 5
• RUNX1::ETO translocations must precede CSF3R mutations to promote acute myeloid leukemia development.
  Sarah A Carratt, Garth L Kong, Cody Coblentz, Zachary Schonrock, Lauren Maloney, Ben Weeder, Will Yashar, Rowan Callahan, Hunter Blaylock, Colin Coleman, Dan Coleman, ...> ;Leukemia. 2023 May 1
• Asxl1 deletion disrupts MYC and RNA polymerase II function in granulocyte progenitors.
  Theodore P Braun, Joseph Estabrook, Zachary Schonrock, Brittany M Curtiss, Lucie Darmusey, Jommel Macaraeg, Trevor Enright, Cody Coblentz, Rowan Callahan, William Yash...> ;Leukemia. 2023 Feb 1
• Case Report:,, andmutation in tyrosine kinase-independent resistant chronic myeloid leukemia progressing to chronic myelomonocytic leukemia-like accelerated phase.
  Emmanuella Oyogoa, Lukas Streich, Philipp W Raess, Theodore Braun> ;Frontiers in Oncology. 2023 Jan 1
• 13 citations
  Mutated SETBP1 activates transcription of Myc programs to accelerate CSF3R-driven myeloproliferative neoplasms.
  Sarah A Carratt, Garth L Kong, Brittany M Curtiss, Zachary Schonrock, Lauren Maloney, Breanna N Maniaci, Hunter Z Blaylock, Adrian Baris, Brian J Druker, Theodore P Br...> ;Blood. 2022 Aug 11
• 67 citations
  Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.
  Daniel Bottomly, Nicola Long, Anna Reister Schultz, Stephen E Kurtz, Cristina E Tognon, Kara Johnson, Melissa Abel, Anupriya Agarwal, Sammantha Avaylon, Erik Benton, A...> ;Cancer Cell. 2022 Aug 8
• 7 citations
  GoPeaks: histone modification peak calling for CUT&Tag.
  William M Yashar, Garth Kong, Jake VanCampen, Brittany M Curtiss, Daniel J Coleman, Lucia Carbone, Galip Gürkan Yardimci, Julia E Maxson, Theodore P Braun> ;Genome Biology. 2022 Jul 4
• 4 citations
  PU.1 and MYC transcriptional network defines synergistic drug responses to KIT and LSD1 inhibition in acute myeloid leukemia.
  Brittany M Curtiss, Jake VanCampen, Jommel Macaraeg, Garth L Kong, Akram Taherinasab, Mitsuhiro Tsuchiya, William M Yashar, Yiu H Tsang, Wesley Horton, Daniel J Colema...> ;Leukemia. 2022 Jul 1
• 1 citations
  Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia.
  Theodore P Braun, Mariam Okhovat, Cody Coblentz, Sarah A Carratt, Amy Foley, Zachary Schonrock, Brittany M Curtiss, Kimberly Nevonen, Brett Davis, Brianna Garcia, Dori...> ;Nature Communications. 2022 Jun 16
• 2 citations
  Navigating Challenges in Monitoring Chronic Myeloid Leukemia with Multiple BCR-ABL1 Transcripts
  Brittany M. Smith, Diana Brewer, Brian J. Druker, Theodore P. Braun> ;Case Reports in Oncology. 2021 Nov 29
• 25 citations
  Chronic cerebral lipocalin 2 exposure elicits hippocampal neuronal dysfunction and cognitive impairment.
  Brennan Olson, Xinxia Zhu, Mason A. Norgard, Parham Diba, Peter R. Levasseur, Abby C. Buenafe, Christian Huisman, Kevin G. Burfeind, Garth L. Kong, Theodore P. Braun, ...> ;Brain, Behavior, and Immunity. 2021 Jul 7
• 13 citations
  Mutant SETBP1 enhances NRAS-driven MAPK pathway activation to promote aggressive leukemia
  Sarah A. Carratt, Theodore P. Braun, Cody Coblentz, Zachary Schonrock, Rowan Callahan, Brittany M. Smith, Lauren Maloney, Amy Foley, Julia E. Maxson> ;Leukemia. 2021 May 17
• 97 citations
  An expanded universe of cancer targets.
  William C. Hahn, Joel S. Bader, Theodore P. Braun, Andrea Califano, Paul A. Clemons, Brian J. Druker, Andrew J. Ewald, Haian Fu, Subhashini Jagu, Christopher J. Kemp, ...> ;Cell. 2021 Mar 4
• BCR-ABL+ Chronic Myeloid Leukemia Arising in a Family With Inherited ANKRD26-Related Thrombocytopenia.
  Aaron M. Tsumura, Brian J. Druker, Diana Brewer, Richard D. Press, Theodore P. Braun> ;JCO Precision Oncology. 2021 Feb 19
• Outgrowth of a CSF3R-mutant clone drives a second myeloproliferative neoplasm in a chronic myeloid leukemia patient: a case report.
  Sarah A. Carratt, Diana Brewer, Julia E. Maxson, Brian J. Druker, Theodore P. Braun> ;Biomarker Research. 2021 Jan 30
• 1 citations
  Tyrosine Kinase Inhibitor Discontinuation in Patients With Chronic Myeloid Leukemia: Updates From the LAST Study on Patient-Reported Outcomes and Biomarkers for Relapse.
  Theodore P. Braun, Brian J. Druker> ;JAMA Oncology. 2021 Jan 1
• 20 citations
  Combined inhibition of JAK/STAT pathway and lysine-specific demethylase 1 as a therapeutic strategy in CSF3R/CEBPA mutant acute myeloid leukemia.
  Theodore P. Braun, Cody Coblentz, Brittany M. Smith, Daniel J. Coleman, Zachary Schonrock, Sarah A. Carratt, Rowan Callahan, Breanna Maniaci, Brian J. Druker, Julia E....> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Jun 16
• 205 citations
  Response and Resistance to BCR-ABL1-Targeted Therapies.
  Theodore P. Braun, Christopher A. Eide, Brian J. Druker> ;Cancer Cell. 2020 Apr 13
• 19 citations
  Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia
  Theodore P. Braun, Mariam Okhovat, Cody Coblentz, Sarah A. Carratt, Amy Foley, Zachary Schonrock, Brittany M. Smith, Kimberly A. Nevonen, Brett Davis, Brianna Garcia, ...> ;Nature Communications. 2019 Nov 29
• 41 citations
  MyD88 signalling is critical in the development of pancreatic cancer cachexia.
  Xinxia Zhu, Kevin G. Burfeind, Katherine A. Michaelis, Theodore P. Braun, Brennan Olson, Katherine R. Pelz, Terry K. Morgan, Daniel L. Marks> ;Journal of Cachexia, Sarcopenia and Muscle. 2019 Apr 1
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Abstracts/Posters

• SETBP1 Mutations Accelerate NRAS-Mutant Leukemia
  Theodore Braun, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019